The generation and application of antigen-specific T cell therapies for cancer and viral-associated disease

Authors: Hont, Amy B., Powell, Allison B., Sohai, Danielle K., Valdez, Izabella K., Stanojevic, Maja, Geiger, Ashley E., Chaudhary, Kajal, Dowlati, Ehsan, Bollard, Catherine M., Cruz, Conrad Russell Y.

Source: In Molecular Therapy 1 June 2022 30(6):2130-2152

Engineered Antigen-Specific T Cells Secreting Broadly Neutralizing Antibodies: Combining Innate and Adaptive Immune Response against HIV

Authors: Powell, Allison B., Ren, Yanqin, Korom, Maria, Saunders, Devin, Hanley, Patrick J., Goldstein, Harris, Nixon, Douglas F., Bollard, Catherine M., Lynch, Rebecca M., Jones, R. Brad, Cruz, Conrad Russell Y.

Source: In Molecular Therapy - Methods & Clinical Development 11 December 2020 19:78-88

Human papilloma virus–specific T cells can be generated from naïve T cells for use as an immunotherapeutic strategy for immunocompromised patients

Authors: McCormack, Sarah E. ^*, Cruz, Conrad Russell Y. ^*, Wright, Kaylor E., Powell, Allison B., Lang, Haili, Trimble, Cornelia, Keller, Michael D., Fuchs, Ephraim, Bollard, Catherine M. ^*

Source: In Cytotherapy March 2018 20(3):385-393

Gene-modified, cell-based therapies—an overview

Authors: Powell, Allison B., Williams, Kiara, Cruz, Conrad Russell Y. ^*

Source: In Cytotherapy November 2016 18(11):1351-1359

Nanodepots Encapsulating a Latency Reversing Agent and Broadly Neutralizing Antibody Enhance Natural Killer Cell Cytotoxicity Against an in vitro Model of Latent HIV.

Authors: Ghofrani, Joshua, Bowen, Allan, Chen, Jie, Balakrishnan, Preethi Bala, Powell, Allison B, Cherukula, Kondareddy, Cruz, Conrad Russell Y, Jones, R Brad, Lynch, Rebecca M, Sweeney, Elizabeth E, Fernandes, Rohan

Source: International Journal of Nanomedicine; Jul2023, Vol. 18, p4055-4066, 12p

PLGA nanodepots co-encapsulating prostratin and anti-CD25 enhance primary natural killer cell antiviral and antitumor function.

Authors: Sweeney, Elizabeth E., Balakrishnan, Preethi B., Powell, Allison B., Bowen, Allan, Sarabia, Indra, Burga, Rachel A., Jones, R. Brad, Bosque, Alberto, Cruz, C. Russell Y., Fernandes, Rohan

Source: Nano Research; Mar2020, Vol. 13 Issue 3, p736-744, 9p

Endocytic Markers Associated with the Internalization and Processing of Aspergillus fumigatus Conidia by BEAS-2B Cells.

Authors: Clark, Helen R., Powell, Allison B., Simmons, Kelsey A., Ayubi, Tariq, Kale, Shiv D.

Source: MSphere; Jan/Feb2019, Vol. 4 Issue 1, p1-21, 21p

Human Papillomavirus (HPV)–Specific T-Cells Can be Generated from Unimmunized Donors for Third Party Cell Therapy of HPV-Associated Neoplasms

Authors: Cruz, Conrad Russell Young, McCormack, Sarah, Wright, Kaylor Elizabeth, Powell, Allison B ^*, Lang, Haili ^*, Barese, Cecilia ^*, Trimble, Connie ^*, Keller, Michael ^*, Fuchs, Ephraim J., Bollard, Catherine M.

Source: In Blood 8 December 2017 130 Supplement 1:1923-1923

Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization.

Authors: Powell, Allison B.¹ (AUTHOR), Yadavilli, Sridevi² (AUTHOR), Saunders, Devin³ (AUTHOR), Van Pelt, Stacey¹ (AUTHOR), Chorvinsky, Elizabeth² (AUTHOR), Burga, Rachel A.¹ (AUTHOR), Albihani, Shuroug³ (AUTHOR), Hanley, Patrick J.³ (AUTHOR), Xu, Zhenhua³ (AUTHOR), Pei, Yanxin³ (AUTHOR), Yvon, Eric S.¹ (AUTHOR), Hwang, Eugene I.³ (AUTHOR), Bollard, Catherine M.^1,2 (AUTHOR), Nazarian, Javad² (AUTHOR), Cruz, Conrad Russell Y.^1,3 (AUTHOR) ccruz@childrensnational.org

Source: Journal of Translational Medicine. 9/23/2019, Vol. 17 Issue 1, pN.PAG-N.PAG. 1p.

Subject Terms: *MEDULLOBLASTOMA, *KILLER cells, *CORD blood, *BRAIN cancer, *CHILDHOOD cancer, *BIOCHEMISTRY, *RESEARCH, *HOMOGRAFTS, *GROWTH factors, *RESEARCH methodology, *GLIOMAS, *CELL receptors, *EVALUATION research, *MEDICAL cooperation, *BRAIN tumors, *PHENOMENOLOGY, *COMPARATIVE studies, *NEUTRALIZATION tests, *CELL lines