Genome-wide CRISPR/Cas9 screen identifies AraC-daunorubicin-etoposide response modulators associated with outcomes in pediatric AML

Authors: Nguyen, Nam H. K. ¹, Rafiee, Roya ¹, Parcha, Phani K. ¹, Tagmount, Abderrahmane ², Rubnitz, Jeffrey ³, Ribeiro, Raul ³, Cao, Xueyuan ⁴, Pounds, Stanley B. ⁵, Vulpe, Christopher D. ², Lamba, Jatinder K. ^{1, ∗}

Source: In Blood Advances 11 March 2025 9(5):1078-1091

The St. Jude STEM Clubs: An Afterschool STEM Club for Upper Elementary School Students in Memphis, TN

Authors: Ayers, Katherine A., Wade-Jaimes, Katherine, Wang, Lei, Pennella, Robyn A., Pounds, Stanley B.

Source: Journal of STEM Outreach. Nov 2020 3(1).

Peer Reviewed: Y

Page Count: 14

Sponsoring Agency: National Institutes of Health (NIH) (DHHS)

Descriptors: STEM Education, Clubs, After School Programs, Elementary School Students, Program Effectiveness, Minority Group Students, Program Development

Geographic Terms: Tennessee (Memphis)

Statistical selection of biological models for genome-wide association analyses

Authors: Bi, Wenjian, Kang, Guolian, Pounds, Stanley B.

Source: 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2017 IEEE International Conference on. :150-157 Nov, 2017

Relation: 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

POST: A framework for set-based association analysis in high-dimensional data

Authors: Cao, Xueyuan, George, E. Olusegun, Wang, Mingjuan, Armstrong, Dale B., Cheng, Cheng, Raimondi, Susana, Rubnitz, Jeffrey E., Downing, James R., Kundu, Mondira, Pounds, Stanley B.

Source: 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2017 IEEE International Conference on. :332-338 Nov, 2017

Relation: 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

Statistical Methods Inspired by Challenges in Pediatric Cancer Multi-omics

Authors: Cao, Xueyuan, Elsayed, Abdelrahman H., Pounds, Stanley B.

Source: Methods in molecular biology. 2629:349-373

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633031159&indx=1&recIds=ETOCRN633031159

Clinical characteristics and outcomes of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis managed with different cytoreductive methods

Authors: Christakopoulos, Georgios E., Walker, Kendra N., Smith, Jesse, Takemoto, Clifford M., Zheng, Yan, Pui, Ching‐Hon, Ribeiro, Raul C., Wang, Lei, Pounds, Stanley B., Rubnitz, Jeffrey E., Inaba, Hiroto

Source: Cancer. 129(12):1873-1884

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185467279.0x000001&indx=1&recIds=ETOCvdc_100185467279.0x000001

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Authors: Gao, Qingsong, Ryan, Sarra L., Iacobucci, Ilaria, Ghate, Pankaj S., Cranston, Ruth E., Schwab, Claire, Elsayed, Abdelrahman H., Shi, Lei, Pounds, Stanley, Lei, Shaohua, Baviskar, Pradyuamna, Pei, Deqing, Cheng, Cheng, Bashton, Matthew, Sinclair, Paul, Bentley, David R., Ross, Mark T., Kingsbury, Zoya, James, Terena, Roberts, Kathryn G., Devidas, Meenakshi, Fan, Yiping, Chen, Wenan, Chang, Ti-Cheng, Wu, Gang, Carroll, Andrew, Heerema, Nyla, Valentine, Virginia, Valentine, Marcus, Yang, Wenjian, Yang, Jun J., Moorman, Anthony V., Harrison, Christine J., Mullighan, Charles G.

Source: In Blood 24 August 2023 142(8):711-723

Clinical impact of minimal residual disease in blood and bone marrow of children with acute myeloid leukemia

Authors: Karol, Seth E., Coustan-Smith, Elaine, Pounds, Stanley, Wang, Lei, Inaba, Hiroto, Ribeiro, Raul C., Pui, Ching-Hon, Klco, Jeffery M., Rubnitz, Jeffrey E.

Source: In Blood Advances 25 July 2023 7(14):3651-3657

SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia

Authors: Marrero, Richard J., Cao, Xueyuan, Wu, Huiyun, Elsayed, Abdelrahman H., Klco, Jeffery M., Ribeiro, Raul C., Rubnitz, Jeffrey E., Ma, Xiaotu, Meshinchi, Soheil, Aplenc, Richard, Kolb, E. Anders, Ries, Rhonda E., Alonzo, Todd A., Pounds, Stanley B., Lamba, Jatinder K.

Source: In Blood Advances 13 June 2023 7(11):2538-2550

Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML

Authors: Nguyen, Nam H. K., Rafiee, Roya, Tagmount, Abderrahmane, Sobh, Amin, Loguinov, Alex, de Jesus Sosa, Angelica K., Elsayed, Abdelrahman H., Gbadamosi, Mohammed, Seligson, Nathan, Cogle, Christopher R., Rubnitz, Jeffery, Ribeiro, Raul, Downing, James, Cao, Xueyuan, Pounds, Stanley B., Vulpe, Christopher D., Lamba, Jatinder K.

Source: In Blood Advances 9 May 2023 7(9):1769-1783

Polygenic Ara-C Response Score Identifies Pediatric Patients With Acute Myeloid Leukemia in Need of Chemotherapy Augmentation

Authors: Elsayed, Abdelrahman H., Cao, Xueyuan, Mitra, Amit K., Wu, Huiyun, Raimondi, Susana, Cogle, Christopher, Al-Mansour, Zeina, Ribeiro, Raul C., Gamis, Alan, Kolb, Edward Anders, Aplenc, Richard, Alonzo, Todd A., Meshinchi, Soheil, Rubnitz, Jeffrey, Pounds, Stanley, Lamba, Jatinder K.

Source: Journal of clinical oncology. 40(7):772-783

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151750083.0x000001&indx=1&recIds=ETOCvdc_100151750083.0x000001

Changes in body mass index, weight, and height in children with acute myeloid leukemia and the associations with outcome

Authors: Iijima, Mayuko ^*, Stall, Melanie ^*, Wang, Lei, Panetta, John C., Triplett, Brandon M., Pui, Ching-Hon, Ribeiro, Raul C., Rubnitz, Jeffrey E., Pounds, Stanley B., Inaba, Hiroto ^*

Source: In Blood Advances 10 May 2022 6(9):2824-2834

Molecular classification improves risk assessment in adult BCR-ABL1–negative B-ALL

Authors: Paietta, Elisabeth ^*, Roberts, Kathryn G. ^*, Wang, Victoria, Gu, Zhaohui, Buck, Georgina A.N., Pei, Deqing, Cheng, Cheng, Levine, Ross L., Abdel-Wahab, Omar, Cheng, Zhongshan, Wu, Gang, Qu, Chunxu, Shi, Lei, Pounds, Stanley, Willman, Cheryl L., Harvey, Richard, Racevskis, Janis, Barinka, Jan, Zhang, Yanming, Dewald, Gordon W., Ketterling, Rhett P., Alejos, David, Lazarus, Hillard M., Luger, Selina M., Foroni, Letizia, Patel, Bela, Fielding, Adele K., Melnick, Ari, Marks, David I., Moorman, Anthony V., Wiernik, Peter H., Rowe, Jacob M., Tallman, Martin S., Goldstone, Anthony H., Mullighan, Charles G. ^{†, *}, Litzow, Mark R. ^{†, *}

Source: In Blood 16 September 2021 138(11):948-958

Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma

Authors: Shaw, Timothy I., Pounds, Stanley, Cao, Xueyuan, Ma, Jing, Palacios, Gustavo, Mason, John, Perkins, Sherrie, Wu, Gang, Fan, Yiping, Wang, Jian, Zhou, Xin, Obermayer, Alyssa, Kinney, Marsha C., Kraveka, Jacqueline, Gross, Thomas, Sandlund, John, Zhang, Jinghui, Mullighan, Charles, Lim, Megan S., Leventaki, Vasiliki

Source: Leukemia; January 2025, Vol. 39 Issue: 1 p199-210, 12p

Pediatric Myeloid Neoplasms With UBTF Tandem Duplications: Morphologic, Immunophenotypic, and Clinical Characterization.

Authors: Khanlari, Mahsa, Wang, Wei, Ni, Yonghui, Mead, Paul E., Umeda, Masayuki, Westover, Tami, Ma, Jing, Rubnitz, Jeffrey E., Barajas, Juan M., Pounds, Stanley, Klco, Jeffery M.

Source: American Journal of Surgical Pathology; Apr2025, Vol. 49 Issue 4, p353-362, 10p

DNA Methylation‐Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia

Authors: Buelow, Daelynn R., Anderson, Jason T., Pounds, Stanley B., Shi, Lei, Lamba, Jatinder K., Hu, Shuiying, Gibson, Alice A., Goodwin, Emily A., Sparreboom, Alex, Baker, Sharyn D.

Source: Clinical and translational science. 14(1):137-142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114836746.0x000001&indx=1&recIds=ETOCvdc_100114836746.0x000001

Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia.

Authors: Chang, Ti-Cheng, Chen, Wenan, Qu, Chunxu, Cheng, Zhongshan, Hedges, Dale, Elsayed, Abdelrahman, Pounds, Stanley B., Shago, Mary, Rabin, Karen R., Raetz, Elizabeth A., Devidas, Meenakshi, Cheng, Cheng, Angiolillo, Anne, Baviskar, Pradyuamna, Borowitz, Michael, Burke, Michael J., Carroll, Andrew, Carroll, William L., Chen, I-Ming, Harvey, Richard

Source: Journal of Clinical Oncology; 10/10/2024, Vol. 42 Issue 29, p3491-3503, 15p

Comparison of DNA methylation based classification models for precision diagnostics of central nervous system tumors.

Authors: Tran, Quynh T., Breuer, Alex, Lin, Tong, Tatevossian, Ruth, Allen, Sariah J., Clay, Michael, Furtado, Larissa V., Chen, Mark, Hedges, Dale, Michael, Tylman, Robinson, Giles, Northcott, Paul, Gajjar, Amar, Azzato, Elizabeth, Shurtleff, Sheila, Ellison, David W., Pounds, Stanley, Orr, Brent A.

Source: NPJ Precision Oncology; 10/2/2024, Vol. 8 Issue 1, p1-12, 12p

Subject Terms: CENTRAL nervous system tumors, K-nearest neighbor classification, DEEP learning, CHILDREN'S hospitals, TUMOR classification

Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study

Authors: Karol, Seth E, Alexander, Thomas B, Budhraja, Amit, Pounds, Stanley B, Canavera, Kristin, Wang, Lei, Wolf, Joshua, Klco, Jeffery M, Mead, Paul E, Das Gupta, Soumyasri, Kim, Su Y, Salem, Ahmed Hamed, Palenski, Tammy, Lacayo, Norman J, Pui, Ching-Hon, Opferman, Joseph T, Rubnitz, Jeffrey E ^*

Source: In The Lancet Oncology April 2020 21(4):551-560

Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia

Authors: Autry, Robert J., Paugh, Steven W., Carter, Robert, Shi, Lei, Liu, Jingjing, Ferguson, Daniel C., Lau, Calvin E., Bonten, Erik J., Yang, Wenjian, McCorkle, J. Robert, Beard, Jordan A., Panetta, John C., Diedrich, Jonathan D., Crews, Kristine R., Pei, Deqing, Coke, Christopher J., Natarajan, Sivaraman, Khatamian, Alireza, Karol, Seth E., Lopez-Lopez, Elixabet, Diouf, Barthelemy, Smith, Colton, Gocho, Yoshihiro, Hagiwara, Kohei, Roberts, Kathryn G., Pounds, Stanley, Kornblau, Steven M., Stock, Wendy, Paietta, Elisabeth M., Litzow, Mark R., Inaba, Hiroto, Mullighan, Charles G., Jeha, Sima, Pui, Ching-Hon, Cheng, Cheng, Savic, Daniel, Yu, Jiyang, Gawad, Charles, Relling, Mary V., Yang, Jun J., Evans, William E.

Source: Nature cancer. 1(3):329-344

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172463486.0x000001&indx=1&recIds=ETOCvdc_100172463486.0x000001