SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

Authors: Lachiondo-Ortega, Sofia ^{1, 30}, Rejano-Gordillo, Claudia M. ^{1, 2, 3, 30}, Simon, Jorge ^{1, 4}, Lopitz-Otsoa, Fernando ¹, C. Delgado, Teresa ¹, Mazan-Mamczarz, Krystyna ⁵, Goikoetxea-Usandizaga, Naroa ¹, Zapata-Pavas, L. Estefanía ¹, García-del Río, Ana ⁶, Guerra, Pietro ⁷, Peña-Sanfélix, Patricia ¹, Hermán-Sánchez, Natalia ⁸, Al-Abdulla, Ruba ^{9, 10}, Fernandez-Rodríguez, Carmen ¹, Azkargorta, Mikel ^{4, 11}, Velázquez-Cruz, Alejandro ¹², Guyon, Joris ^{13, 14}, Martín, César ³, Zalamea, Juan Diego ¹⁵, Egia-Mendikute, Leire ⁶, Sanz-Parra, Arantza ¹, Serrano-Maciá, Marina ¹, González-Recio, Irene ¹, Gonzalez-Lopez, Monika ¹⁶, Martínez-Cruz, Luis Alfonso ¹, Pontisso, Patrizia ⁷, Aransay, Ana M. ¹⁶, Barrio, Rosa ¹⁷, Sutherland, James D. ¹⁷, Abrescia, Nicola G.A. ^{15, 18}, Elortza, Félix ^{4, 11}, Lujambio, Amaia ^{19, 20, 21, 22}, Banales, Jesus M. ^{4, 18, 23, 24}, Luque, Raúl M. ⁸, Gahete, Manuel D. ⁸, Palazón, Asís ^{6, 18}, Avila, Matias A. ^{4, 25, 26}, G. Marin, Jose J. ^{4, 27}, De, Supriyo ⁵, Daubon, Thomas ²⁸, Díaz-Quintana, Antonio ¹², Díaz-Moreno, Irene ¹², Gorospe, Myriam ⁵, Rodríguez, Manuel S. ²⁹, Martínez-Chantar, María Luz ^{1, 4, 31, ∗}

Source: In Cell Reports 26 March 2024 43(3)

The protease activated receptor 2 - CCAAT/enhancer-binding protein beta - SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis

Authors: Villano, Gianmarco, Novo, Erica, Turato, Cristian, Quarta, Santina, Ruvoletto, Mariagrazia, Biasiolo, Alessandra, Protopapa, Francesca, Chinellato, Monica, Martini, Andrea, Trevellin, Elisabetta, Granzotto, Marnie, Cannito, Stefania, Cendron, Laura, De Siervi, Silvia, Guido, Maria, Parola, Maurizio, Vettor, Roberto, Pontisso, Patrizia

Source: In Molecular Metabolism March 2024 81

SerpinB3: A Multifaceted Player in Health and Disease—Review and Future Perspectives.

Authors: Cagnin, Silvia¹ (AUTHOR) silvia.cgn@gmail.com, Pontisso, Patrizia¹ (AUTHOR) patrizia@unipd.it, Martini, Andrea¹ (AUTHOR)

Source: Cancers. Jul2024, Vol. 16 Issue 14, p2579. 15p.

Subject Terms: *PROTEIN metabolism, *CANCER invasiveness, *NEOPLASTIC cell transformation, *TUMOR markers, *PROTEASE inhibitors, *GENE expression, *LIVER diseases, *FIBROSIS, *CELL death, *CELL survival, *DISEASE progression

Hepatocyte-Specific Deletion of HIF2α Prevents NASH-Related Liver Carcinogenesis by Decreasing Cancer Cell Proliferation

Authors: Foglia, Beatrice, Sutti, Salvatore, Cannito, Stefania, Rosso, Chiara, Maggiora, Marina, Autelli, Riccardo, Novo, Erica, Bocca, Claudia, Villano, Gianmarco, Ramavath, Naresh Naik, Younes, Ramy, Tusa, Ignazia, Rovida, Elisabetta, Pontisso, Patrizia, Bugianesi, Elisabetta, Albano, Emanuele, Parola, Maurizio

Source: In Cellular and Molecular Gastroenterology and Hepatology 2022 13(2):459-482

Coronary artery calcium on standard chest computed tomography predicts cardiovascular events after liver transplantation

Authors: Zorzi, Alessandro, Brunetti, Giulia, Cardaioli, Francesco, D'Arcangelo, Francesca, Fabris, Tommaso, Gambato, Martina, Iliceto, Sabino, Martini, Andrea, Mattesi, Giulia, Peluso, Claudia, Polacco, Marina, Sartori, Chiara, Lorenzoni, Giulia, Feltracco, Paolo, Angeli, Paolo, Burra, Patrizia, Cillo, Umberto, Pontisso, Patrizia

Source: In International Journal of Cardiology 15 September 2021 339:219-224

Natural history of acute kidney disease in patients with cirrhosis

Authors: Tonon, Marta, Rosi, Silvia, Gambino, Carmine Gabriele, Piano, Salvatore, Calvino, Valeria, Romano, Antonietta, Martini, Andrea, Pontisso, Patrizia, Angeli, Paolo

Source: In Journal of Hepatology March 2021 74(3):578-583

Le complexe antigène de carcinome à cellules squameuses-IgM (SCCA-IgM) est associé à la pneumopathie interstitielle diffuse dans la sclérodermie systémique

Authors: Zanatta, Elisabetta, Martini, Andrea, Scarpieri, Elena, Biasiolo, Alessandra, Ortolan, Augusta, Benvenuti, Francesco, Cozzi, Franco, Pontisso, Patrizia, Doria, Andrea ^*

Source: In Revue du rhumatisme December 2020 87(6):472-476

Labelled micelles for the delivery of cytotoxic Cu(II) and Ru(III) compounds in the treatment of aggressive orphan cancers: Design and biological in vitro data

Authors: Brustolin, Leonardo, Pettenuzzo, Nicolò, Nardon, Chiara, Quarta, Santina, Montagner, Isabella, Pontisso, Patrizia, Rosato, Antonio, Conte, Pierfranco, Merigliano, Stefano, Fregona, Dolores

Source: In Journal of Inorganic Biochemistry December 2020 213

Squamous cell carcinoma antigen-IgM (SCCA-IgM) is associated with interstitial lung disease in systemic sclerosis

Authors: Zanatta, Elisabetta, Martini, Andrea, Scarpieri, Elena, Biasiolo, Alessandra, Ortolan, Augusta, Benvenuti, Francesco, Cozzi, Franco, Pontisso, Patrizia, Doria, Andrea

Source: In Joint Bone Spine July 2020 87(4):331-335

Hyperdynamic circulatory syndrome in a mouse model transgenic for SerpinB3

Authors: Villano, Gianmarco, Verardo, Alberto, Martini, Andrea, Brocco, Silvia, Pesce, Paola, Novo, Erica, Parola, Maurizio, Sacerdoti, David, Di Pascoli, Marco, Fedrigo, Marny, Castellani, Chiara, Angelini, Annalisa, Pontisso, Patrizia, Bolognesi, Massimo

Source: In Annals of Hepatology January-February 2020 19(1):36-43

PreS1 peptide-functionalized gold nanostructures with SERRS tags for efficient liver cancer cell targeting

Authors: Biscaglia, Francesca, Quarta, Santina, Villano, Gianmarco, Turato, Cristian, Biasiolo, Alessandra, Litti, Lucio, Ruzzene, Maria, Meneghetti, Moreno, Pontisso, Patrizia, Gobbo, Marina

Source: In Materials Science & Engineering C October 2019 103

1-Piperidine Propionic Acid Protects from Septic Shock Through Protease Receptor 2 Inhibition.

Authors: Luisetto, Roberto, Scarpa, Marco, Villano, Gianmarco, Martini, Andrea, Quarta, Santina, Ruvoletto, Mariagrazia, Guerra, Pietro, Scarpa, Melania, Chinellato, Monica, Biasiolo, Alessandra, Campigotto, Edoardo, Basso, Daniela, Fassan, Matteo, Pontisso, Patrizia

Source: International Journal of Molecular Sciences; Nov2024, Vol. 25 Issue 21, p11662, 19p

Subject Terms: SEPTIC shock, PROTEASE-activated receptors, PROPIONIC acid, SMALL molecules, ENDOTOXEMIA

Protease activated receptor 2 as a novel druggable target for the treatment of metabolic dysfunction-associated fatty liver disease and cancer.

Authors: Villano, Gianmarco, Pontisso, Patrizia

Source: Frontiers in Immunology; 2024, p1-8, 8p

Subject Terms: HEPATITIS, PROTEASE-activated receptors, METABOLIC disorders, LIVER diseases, INSULIN resistance

SerpinB3 induces dipeptidyl-peptidase IV/CD26 expression and its metabolic effects in hepatocellular carcinoma

Authors: Fasolato, Silvano, Trevellin, Elisabetta, Ruvoletto, Mariagrazia, Granzotto, Marnie, Zanus, Giacomo, Boscaro, Elisa, Babetto, Enrico, Terrin, Liliana, Battocchio, Maria Alberta, Ciscato, Francesco, Turato, Cristian, Quarta, Santina, Cillo, Umberto, Pontisso, Patrizia, Vettor, Roberto

Source: In Life Sciences 1 May 2018 200:134-141

New molecular targets for functionalized nanosized drug delivery systems in personalized therapy for hepatocellular carcinoma

Authors: Turato, Cristian, Balasso, Anna, Carloni, Vinicio, Tiribelli, Claudio, Mastrotto, Francesca, Mazzocca, Antonio, Pontisso, Patrizia

Source: In Journal of Controlled Release 28 December 2017 268:184-197

Serum Vascular Adhesion Protein-1 and Endothelial Dysfunction in Hepatic Cirrhosis: Searching for New Prognostic Markers.

Authors: Fasolato, Silvano, Bonaiuto, Emanuela, Rossetto, Monica, Vanzani, Paola, Ceccato, Fabio, Vittadello, Fabio, Zennaro, Lucio, Rigo, Adelio, Mammano, Enzo, Angeli, Paolo, Pontisso, Patrizia, Di Paolo, Maria Luisa

Source: International Journal of Molecular Sciences; Jul2024, Vol. 25 Issue 13, p7309, 17p

Subject Terms: PROGNOSIS, ENDOTHELIAL cells, VASCULAR cell adhesion molecule-1, ENDOTHELIUM diseases, CIRRHOSIS of the liver, CD54 antigen

Inhibition of Protease-Activated Receptor-2 Activation in Parkinson's Disease Using 1-Piperidin Propionic Acid.

Authors: Quarta, Santina, Sandre, Michele, Ruvoletto, Mariagrazia, Campagnolo, Marta, Emmi, Aron, Biasiolo, Alessandra, Pontisso, Patrizia, Antonini, Angelo

Source: Biomedicines; Jul2024, Vol. 13 Issue 7, p1623, 10p

Subject Terms: PARKINSON'S disease, PROPIONIC acid, NEUROGLIA, FIBROBLASTS, MICROGLIA

Re-programming pullulan for targeting and controlled release of doxorubicin to the hepatocellular carcinoma cells

Authors: Balasso, Anna, Salmaso, Stefano, Pontisso, Patrizia, Rosato, Antonio, Quarta, Santina, Malfanti, Alessio, Mastrotto, Francesca, Caliceti, Paolo

Source: In European Journal of Pharmaceutical Sciences 30 May 2017 103:104-115

AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)

Authors: Alisi, Anna, Balsano, Clara, Bernabucci, Veronica, Berzigotti, Annalisa, Brunetto, Maurizia, Bugianesi, Elisabetta, Burra, Patrizia, Calvaruso, Vincenza, Cariani, Elisabetta, Coco, Barbara, Colle, Isabelle, Critelli, Rosina, De Martin, Eleonora, Del Buono, Mariagrazia, Fabregat, Isabel, Faillaci, Francesca, Fattovich, Giovanna, Floreani, Annarosa, Garcia-Tsao, Guadalupe, Housset, Chantal, Karampatou, Aimilia, Lei, Barbara, Mangia, Alessandra, Martinez-Chantar, Maria Luz, Milosa, Fabiola, Morisco, Filomena, Nasta, Paola, Ozben, Tomris, Pollicino, Teresa, Ponti, Maria Laura, Pontisso, Patrizia, Reeves, Helen, Rendina, Maria, Rodríguez-Castro, Kryssia Isabel, Sagnelli, Caterina, Sebastiani, Giada, Smedile, Antonella, Taliani, Gloria, Vandelli, Carmen, Vanni, Ester, Villa, Erica, Vukotic, Ranka, Zignego, Anna Linda, Rodríguez-Castro, Kryssia, Guarino, Maria, Mazzella, Giuseppe

Source: In Digestive and Liver Disease August 2016 48(8):860-868

Squamous cell carcinoma antigen-IgM is associated with hepatocellular carcinoma in patients with cirrhosis: A prospective study

Authors: Biasiolo, Alessandra, Trotta, Elisa, Fasolato, Silvano, Ruvoletto, Mariagrazia, Martini, Andrea, Gallotta, Andrea, Fassina, Giorgio, Angeli, Paolo, Gatta, Angelo, Pontisso, Patrizia

Source: In Digestive and Liver Disease February 2016 48(2):197-202