IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases.

Authors: Richard Seonghun Nho, Polla Hergert

Source: PLoS ONE, Vol 9, Iss 4, p e94616 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3984186?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cef77604a4684a9db3d50b466d0a77dc

FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.

Authors: Richard Seonghun Nho, Mark Peterson, Polla Hergert, Craig A Henke

Source: PLoS ONE, Vol 8, Iss 4, p e61017 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3620276?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/82b7b17e6bc041ba9395f315f88ec1f4

Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.

Authors: G, DeLuca Jennifer, Yimin, Dong, Polla, Hergert, Joshua, Strauss, M, Hickey Jennifer, D, Salmon E, F, McEwen Bruce

Source: Molecular Biology of the Cell; February 2005, Vol. 16 Issue: 2 p519-31, 13p

Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments.

Authors: L, Kline-Smith Susan, Alexey, Khodjakov, Polla, Hergert, E, Walczak Claire

Source: Molecular Biology of the Cell; March 2004, Vol. 15 Issue: 3 p1146-59, 14p