The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice

Authors: Yura, Yoshimitsu, Miura-Yura, Emiri, Katanasaka, Yasufumi, Min, Kyung-Duk, Chavkin, Nicholas, Polizio, Ariel H., Ogawa, Hayato, Horitani, Keita, Doviak, Heather, Evans, Megan A., Sano, Miho, Wang, Ying, Boroviak, Katharina, Philippos, George, Domingues, Ana Filipa, Vassiliou, George, Sano, Soichi, Walsh, Kenneth

Source: Circulation research. 129(6):684-698

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190156269.0x000001&indx=1&recIds=ETOCvdc_100190156269.0x000001

Tet2 -mediated clonal hematopoiesis modestly improves neurological deficits and is associated with inflammation resolution in the subacute phase of experimental stroke.

Authors: Evans, Megan A., Chavkin, Nicholas W., Sano, Soichi, Sun, Hanna, Sardana, Taneesha, Ravi, Ramya, Doviak, Heather, Wang, Ying, Yura, Yoshimitsu, Polizio, Ariel H., Horitani, Keita, Ogawa, Hayato, Hirschi, Karen K., Walsh, Kenneth

Source: Frontiers in Cellular Neuroscience; 2024, p1-12, 12p

Subject Terms: ENCEPHALITIS, ISCHEMIC stroke, STROKE, CEREBRAL ischemia, CARDIOVASCULAR diseases

Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism.

Authors: Polizio, Ariel H., Marino, Lucila, Kyung-Duk Min, Yoshimitsu Yura, Rolauer, Luca, Cochran, Jesse D., Evans, Megan A., Park, Eunbee, Doviak, Heather, Miura-Yura, Emiri, Good, Miranda E., Wolpe, Abigail G., Grandoch, Maria, Isakson, Brant E., Walsh, Kenneth

Source: Circulation Research; 10/11/2024, Vol. 135 Issue 9, p933-950, 18p

Clonal Hematopoiesis Increases Hypertension and Sympathetic Activity and Is Reversed by Renal Denervation.

Authors: Polizio, Ariel H., Marino, Lucila, Rolauer, Luca, Doviak, Heather, Grandoch, Maria, Toldo, Stefano, Walsh, Kenneth

Source: Hypertension (0194911X); Mar2025, Vol. 82 Issue 3, pe28-e30, 3p

Factors influencing hepatic metabolism of antihypertensive drugs: impact on clinical response

Authors: Höcht, Christian, Bertera, Facundo M., Santander Plantamura, Yanina, Parola, Luciano, Del Mauro, Julieta S., Polizio, Ariel H.

Source: Expert opinion on drug metabolism and toxicology. 15(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106462043.0x000001&indx=1&recIds=ETOCvdc_100106462043.0x000001

Fructose increases corticosterone production in association with NADPH metabolism alterations in rat epididymal white adipose tissue

Authors: Prince, Paula D., Santander, Yanina A., Gerez, Estefania M., Höcht, Christian, Polizio, Ariel H., Mayer, Marcos A., Taira, Carlos A., Fraga, Cesar G., Galleano, Monica, Carranza, Andrea

Source: In The Journal of Nutritional Biochemistry August 2017 46:109-116

An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular Effects.

Authors: Martinez Naya, Nadia, Kelly, Jazmin, Corna, Giuliana, Golino, Michele, Polizio, Ariel H., Abbate, Antonio, Toldo, Stefano, Mezzaroma, Eleonora

Source: Molecules; Jan2024, Vol. 29 Issue 2, p473, 25p

Subject Terms: CANNABIDIOL, PHARMACOKINETICS, ION channels, INFLAMMATION, CONOTOXINS, IMMUNE system

What is the Real Efficacy of Beta-Blockers for the Treatment of Essential Hypertension?

Authors: Hocht, Christian, Bertera, Facundo M., Del Mauro, Julieta S., Santander Plantamura, Yanina, Taira, Carlos A., Polizio, Ariel H

Source: Current pharmaceutical design. 23(31):4658-4677

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100077939812.0x000001&indx=1&recIds=ETOCvdc_100077939812.0x000001

Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction.

Authors: Cochran, Jesse D., Yoshimitsu Yura, Thel, Mark C., Doviak, Heather, Polizio, Ariel H., Arai, Yuka, Arai, Yohei, Horitani, Keita, Park, Eunbee, Chavkin, Nicholas W., Kour, Anupreet, Sano, Soichi, Mahajan, Nitin, Evans, Megan, Huba, Mahalia, Martinez Naya, Nadia, Sun, Hanna, Young Ho Ban, Hirschi, Karen K., Toldo, Stefano

Source: Circulation; 10/10/2023, Vol. 148 Issue 15, p1165-1178, 14p

Heterotrimeric Gi Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

Authors: Polizio, Ariel H., Chinchilla, Pilar, Chen, Xiaole, Kim, Sangbumn, Manning, David R., Riobo, Natalia A.

Source: In Journal of Biological Chemistry 3 June 2011 286(22):19589-19596

Nitric oxide synthase-like dependent NO production enhances heme oxygenase up-regulation in ultraviolet-B-irradiated soybean plants

Authors: Santa-Cruz, Diego M., Pacienza, Natalia A., Polizio, Ariel H., Balestrasse, Karina B., Tomaro, Maria L., Yannarelli, Gustavo G.

Source: In Phytochemistry 2010 71(14):1700-1707

Losartan exerts renoprotection through NAD(P)H oxidase downregulation in a renovascular model of hypertension

Authors: Polizio, Ariel H., Balestrasse, Karina B., Gornalusse, German G., Gorzalczany, Susana B., Santa-Cruz, Diego M., Yannarelli, Gustavo G., Peña, Clara, Tomaro, María L.

Source: In Regulatory Peptides 2009 156(1):28-33

Clonal Hematopoiesis: Connecting Aging and Inflammation in Atherosclerosis.

Authors: Polizio, Ariel H., Park, Eunbee, Walsh, Kenneth

Source: Current Atherosclerosis Reports; Mar2023, Vol. 25 Issue 3, p105-111, 7p

Heme oxygenase up-regulation under salt stress protects nitrogen metabolism in nodules of soybean plants

Authors: Zilli, Carla G., Balestrasse, Karina B., Yannarelli, Gustavo G., Polizio, Ariel H., Santa-Cruz, Diego M., Tomaro, María L.

Source: In Environmental and Experimental Botany 2008 64(1):83-89

Experimental -Mediated Clonal Hematopoiesis Promotes Inflammation and Accelerates Heart Failure.

Authors: Kyung-Duk Min, Polizio, Ariel H., Kour, Anupreet, Thel, Mark C., Walsh, Kenneth, Min, Kyung-Duk

Source: Journal of the American Heart Association; 10/4/2022, Vol. 11 Issue 19, p1-3, 3p

Nebivolol is more effective than atenolol for blood pressure variability attenuation and target organ damage prevention in L-NAME hypertensive rats.

Authors: Del Mauro, Julieta S., Prince, Paula D., Santander Plantamura, Yanina, Allo, Miguel A., Parola, Luciano, Fernandez Machulsky, Nahuel, Morettón, Marcela A., Bin, Eliana P., González, Germán E., Bertera, Facundo M., Carranza, Andrea, Berg, Gabriela, Taira, Carlos A., Donato, Martín, Chiappetta, Diego A., Polizio, Ariel H., Höcht, Christian

Source: Hypertension Research; Jul2021, Vol. 44 Issue 7, p791-802, 12p

BEHAVIOUR OF THE ANTI-OXIDANT DEFENCE SYSTEM AND HEME OXYGENASE-1 PROTEIN EXPRESSION IN FRUCTOSE-HYPERTENSIVE RATS.

Authors: Polizio, Ariel H¹, Gonzales, Soledad¹, Muñoz, Marina C¹, Peña, Clara¹, Tomaro, María L¹ ptomaro@ffyb.uba.ar

Source: Clinical & Experimental Pharmacology & Physiology. Aug2006, Vol. 33 Issue 8, p734-739. 6p. 4 Charts, 3 Graphs.

Subject Terms: *FRUCTOSE in human nutrition, *CARDIOVASCULAR diseases, *LABORATORY rats, *OXIDATIVE stress, *HEME oxygenase, *PEROXIDATION

Effects of third-generation β-blockers, atenolol or amlodipine on blood pressure variability and target organ damage in spontaneously hypertensive rats.

Authors: Del Mauro, Julieta S., Prince, Paula D., Allo, Miguel A., Plantamura, Yanina Santander, Morettón, Marcela A., González, Germán E., Bertera, Facundo M., Carranza, Andrea, Gorzalczany, Susana B., Chiappetta, Diego A., Morales, Celina, Gelpi, Ricardo J., Taira, Carlos A., Polizio, Ariel H., Donato, Martín, Höcht, Christian, Santander Plantamura, Yanina

Source: Journal of Hypertension; Mar2020, Vol. 38 Issue 3, p536-545, 10p

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