A deep learning approach predicting the activity of COVID-19 therapeutics and vaccines against emerging variants.

Authors: Matson, Robert P., Comba, Isin Y., Silvert, Eli, Niesen, Michiel J. M., Murugadoss, Karthik, Patwardhan, Dhruti, Suratekar, Rohit, Goel, Elizabeth-Grace, Poelaert, Brittany J., Wan, Kanny K., Brimacombe, Kyle R., Venkatakrishnan, AJ, Soundararajan, Venky

Source: NPJ Systems Biology & Applications; 11/27/2024, Vol. 10 Issue 1, p1-10, 10p

Subject Terms: SARS-CoV-2 Omicron variant, DEEP learning, PROJECT method in teaching, SARS-CoV-2, COVID-19 vaccines

Nanoformulation of CCL21 greatly increases its effectiveness as an immunotherapy for neuroblastoma

Authors: Poelaert, Brittany J., Romanova, Svetlana, Knoche, Shelby M., Olson, Madeline T., Sliker, Bailee H., Smits, Kaitlin, Dickey, Brittney L., Moffitt-Holida, Alexandra E.J., Goetz, Benjamin T., Khan, Nuzhat, Smith, Lynette, Band, Hamid, Mohs, Aaron M., Coulter, Donald W., Bronich, Tatiana K., Solheim, Joyce C.

Source: In Journal of Controlled Release 10 November 2020 327:266-283

Beta 2-microglobulin regulates amyloid precursor-like protein 2 expression and the migration of pancreatic cancer cells

Authors: Sliker, Bailee H., Goetz, Benjamin T., Peters, Haley L., Poelaert, Brittany J., Borgstahl, Gloria E. O., Solheim, Joyce C.

Source: Cancer biology & therapy. 20(6):931-940

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110824357.0x000001&indx=1&recIds=ETOCvdc_100110824357.0x000001

The role of tumor heterogeneity in immune-tumor interactions.

Authors: Knoche, Shelby M., Larson, Alaina C., Sliker, Bailee H., Poelaert, Brittany J., Solheim, Joyce C.

Source: Cancer & Metastasis Reviews; Jun2021, Vol. 40 Issue 2, p377-389, 13p

Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer.

Authors: Poelaert, Brittany J.¹ (AUTHOR) bpoelaert@georgiamune.com, Knoche, Shelby M.¹ (AUTHOR) shelby.knoche@unmc.edu, Larson, Alaina C.¹ (AUTHOR) alaina.larson@unmc.edu, Pandey, Poomy¹ (AUTHOR) poomy.pandey@ki.se, Seshacharyulu, Parthasarathy² (AUTHOR) p.seshacharyulu@unmc.edu, Khan, Nuzhat¹ (AUTHOR) nuzkhan75@gmail.com, Maurer, H. Carlo³ (AUTHOR) carlo.maurer@tum.de, Olive, Kenneth P.³ (AUTHOR) kpo2104@cumc.columbia.edu, Sheinin, Yuri⁴ (AUTHOR) ysheinin@mcw.edu, Ahmad, Rizwan² (AUTHOR) rizwan.ahmad@unmc.edu, Singh, Amar B.² (AUTHOR) amar.singh@unmc.edu, Batra, Surinder K.² (AUTHOR) sbatra@unmc.edu, Rachagani, Satyanarayana² (AUTHOR) srachagani@unmc.edu, Solheim, Joyce C.^1,2 (AUTHOR) jsolheim@unmc.edu, Sahni, Sumit (AUTHOR), Mittal, Anubhav (AUTHOR), Samra, Jaswinder (AUTHOR)

Source: Cancers. Apr2021, Vol. 13 Issue 7, p1535-1535. 1p.

Subject Terms: *PANCREATIC tumors, *THERAPEUTICS, *SURVIVAL, *BIOLOGICAL models, *DISEASE progression, *ANIMAL experimentation, *IMMUNOHISTOCHEMISTRY, *PROTEIN precursors, *METASTASIS, *GENE expression, *EPITHELIUM, *DUCTAL carcinoma, *EPITHELIAL cells, *MICE

Geographic Terms: UNITED States