IDH2 Inhibitors Gain a Wildcard Status in the Cancer Therapeutics Competition.

Authors: Piva, Roberto^1,2 (AUTHOR) nariman.gharari@unito.it, Gharari, Nariman¹ (AUTHOR) maria.labradorgranados@unito.it, Labrador, Maria¹ (AUTHOR), Mader, Sylvie³ (AUTHOR) sylvie.mader@umontreal.ca

Source: Cancers. Oct2024, Vol. 16 Issue 19, p3280. 10p.

Subject Terms: *THERAPEUTIC use of antineoplastic agents, *T cells, *BREAST tumors, *IMMUNOTHERAPY, *APOPTOSIS, *IMMUNE system, *CELL differentiation, *GENETICS, *CELL receptors, BREAST tumor prevention

Unlocking the Therapeutic Potential of Algae-Derived Compounds in Hematological Malignancies.

Authors: Vujović, Tamara, Paradžik, Tina, Babić Brčić, Sanja, Piva, Roberto

Source: Cancers; Jan2025, Vol. 17 Issue 2, p318, 29p

Subject Terms: HEMATOLOGIC malignancies, ALGAE, LYMPHOMAS, PLANT extracts, CELL lines, LEUKEMIA, MOLECULAR structure, DRUG synergism

Biomimetic mesoporous vectors enabling the efficient inhibition of wild-type isocitrate dehydrogenase in multiple myeloma cells

Authors: Cauda, Valentina, Xu, Teng Teng, Nunes, Inês, Mereu, Elisabetta, Villata, Simona, Bergaggio, Elisa, Labrador, María, Limongi, Tania, Susa, Francesca, Chiodoni, Angelica, Cumerlato, Michela, Rosso, Giada, Stefania, Rachele, Piva, Roberto

Source: In Microporous and Mesoporous Materials October 2021 325

Gelsius: A Literature-Based Workflow for Determining Quantitative Associations between Genes and Biological Processes

Authors: Abate, Francesco, Acquaviva, Andrea, Ficarra, Elisa, Piva, Roberto, Macii, Enrico

Source: IEEE/ACM Transactions on Computational Biology and Bioinformatics IEEE/ACM Trans. Comput. Biol. and Bioinf. Computational Biology and Bioinformatics, IEEE/ACM Transactions on. 10(3):619-631 May, 2013

Next Generation Sequencing (NGS) Strategies for Genetic Testing of Cerebral Cavernous Malformation (CCM) Disease

Authors: Benedetti, Valerio, Pellegrino, Elisa, Brusco, Alfredo, Piva, Roberto, Retta, Saverio Francesco

Source: Methods in molecular biology. 2152:59-76

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624459853&indx=1&recIds=ETOCRN624459853

IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies

Authors: Bergaggio, Elisa, Riganti, Chiara, Garaffo, Giulia, Vitale, Nicoletta, Mereu, Elisabetta, Bandini, Cecilia, Pellegrino, Elisa, Pullano, Verdiana, Omedè, Paola, Todoerti, Katia, Cascione, Luciano, Audrito, Valentina, Riccio, Anna, Rossi, Antonio, Bertoni, Francesco, Deaglio, Silvia, Neri, Antonino, Palumbo, Antonio, Piva, Roberto ^*

Source: In Blood 10 January 2019 133(2):156-167

Wiskott–Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma

Authors: Menotti, Matteo, Ambrogio, Chiara, Cheong, Taek-Chin, Pighi, Chiara, Mota, Ines, Cassel, Seth, Compagno, Mara, Wang, Qi, Dall'Olio, Riccardo, Minero, Valerio, Poggio, Teresa, Sharma, Geeta, Patrucco, Enrico, Mastini, Cristina, Choudhari, Ramesh, Pich, Achille, Zamo, Alberto, Piva, Roberto, Giliani, Silvia, Mologni, Luca, Collings, Clayton, Kadoch, Cigall, Gambacorti-Passerini, Carlo, Notarangelo, Luigi, Anton, Ines, Voena, Claudia, Chiarle, Roberto

Source: Nature medicine. 25(1):130-140

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100102162154.0x000001&indx=1&recIds=ETOCvdc_100102162154.0x000001

Integration of transcriptional and mutational data simplifies the stratification of peripheral T‐cell lymphoma

Authors: Maura, Francesco, Agnelli, Luca, Leongamornlert, Daniel, Bolli, Niccolò, Chan, Wing C., Dodero, Anna, Carniti, Cristiana, Heavican, Tayla B., Pellegrinelli, Alessio, Pruneri, Giancarlo, Butler, Adam, Bhosle, Shriram G., Chiappella, Annalisa, Di Rocco, Alice, Zinzani, Pier Luigi, Zaja, Francesco, Piva, Roberto, Inghirami, Giorgio, Wang, Wenyi, Palomero, Teresa, Iqbal, Javeed, Neri, Antonino, Campbell, Peter J., Corradini, Paolo

Source: American journal of hematology. 94(6):628-634

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083651063.0x000001&indx=1&recIds=ETOCvdc_100083651063.0x000001

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma

Authors: Schleussner, Nikolai, Merkel, Olaf, Costanza, Mariantonia, Liang, Huan-Chang, Hummel, Franziska, Romagnani, Chiara, Durek, Pawel, Anagnostopoulos, Ioannis, Hummel, Michael, Jöhrens, Korinna, Niedobitek, Antonia, Griffin, Patrick, Piva, Roberto, Sczakiel, Henrike, Woessmann, Wilhelm, Damm-Welk, Christine, Hinze, Christian, Stoiber, Dagmar, Gillissen, Bernd, Turner, Suzanne, Kaergel, Eva, von Hoff, Linda, Grau, Michael, Lenz, Georg, Dörken, Bernd, Scheidereit, Claus, Kenner, Lukas, Janz, Martin, Mathas, Stephan

Source: Leukemia. 32(9):1994-2007

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129124484.0x000001&indx=1&recIds=ETOCvdc_100129124484.0x000001

Transposable elements: The enemies within

Authors: Scarfò, Irene, Pellegrino, Elisa, Mereu, Elisabetta, Inghirami, Giorgio, Piva, Roberto

Source: In Experimental Hematology October 2016 44(10):913-916

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

Authors: Scarfò, Irene ^*, Pellegrino, Elisa ^*, Mereu, Elisabetta ^*, Kwee, Ivo, Agnelli, Luca, Bergaggio, Elisa, Garaffo, Giulia, Vitale, Nicoletta, Caputo, Manuel, Machiorlatti, Rodolfo, Circosta, Paola, Abate, Francesco, Barreca, Antonella, Novero, Domenico, Mathew, Susan, Rinaldi, Andrea, Tiacci, Enrico, Serra, Sara, Deaglio, Silvia, Neri, Antonino, Falini, Brunangelo, Rabadan, Raul, Bertoni, Francesco, Inghirami, Giorgio, Piva, Roberto ^*

Source: In Blood 14 January 2016 127(2):221-232

Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma

Authors: Crescenzo, Ramona, Abate, Francesco, Lasorsa, Elena, Tabbo’, Fabrizio, Gaudiano, Marcello, Chiesa, Nicoletta, Di Giacomo, Filomena, Spaccarotella, Elisa, Barbarossa, Luigi, Ercole, Elisabetta, Todaro, Maria, Boi, Michela, Acquaviva, Andrea, Ficarra, Elisa, Novero, Domenico, Rinaldi, Andrea, Tousseyn, Thomas, Rosenwald, Andreas, Kenner, Lukas, Cerroni, Lorenzo, Tzankov, Alexander, Ponzoni, Maurilio, Paulli, Marco, Weisenburger, Dennis, Chan, Wing C., Iqbal, Javeed, Piris, Miguel A., Zamo’, Alberto, Ciardullo, Carmela, Rossi, Davide, Gaidano, Gianluca, Pileri, Stefano, Tiacci, Enrico, Falini, Brunangelo, Shultz, Leonard D., Mevellec, Laurence, Vialard, Jorge E., Piva, Roberto, Bertoni, Francesco, Rabadan, Raul, Inghirami, Giorgio

Source: In Cancer Cell 13 April 2015 27(4):516-532

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

Authors: Boi, Michela, Rinaldi, Andrea, Kwee, Ivo, Bonetti, Paola, Todaro, Maria, Tabbò, Fabrizio, Piva, Roberto, Rancoita, Paola M.V., Matolcsy, András, Timar, Botond, Tousseyn, Thomas, Rodríguez-Pinilla, Socorro Maria, Piris, Miguel A., Beà, Sílvia, Campo, Elias, Bhagat, Govind, Swerdlow, Steven H., Rosenwald, Andreas, Ponzoni, Maurilio, Young, Ken H., Piccaluga, Pier Paolo, Dummer, Reinhard, Pileri, Stefano, Zucca, Emanuele, Inghirami, Giorgio ^*, Bertoni, Francesco ^*

Source: In Blood 10 October 2013 122(15):2683-2693

Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma

Authors: Bonetti, Paola, Testoni, Monica, Scandurra, Marta, Ponzoni, Maurilio, Piva, Roberto, Mensah, Afua A., Rinaldi, Andrea, Kwee, Ivo, Tibiletti, Maria Grazia, Iqbal, Javeed, Greiner, Timothy C., Chan, Wing-Chung, Gaidano, Gianluca, Piris, Miguel A., Cavalli, Franco, Zucca, Emanuele, Inghirami, Giorgio, Bertoni, Francesco ^*

Source: In Blood 26 September 2013 122(13):2233-2241

microRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

Authors: Liu, Cuiling, Iqbal, Javeed, Teruya-Feldstein, Julie, Shen, Yulei, Dabrowska, Magdalena Julia, Dybkaer, Karen, Lim, Megan S., Piva, Roberto, Barreca, Antonella, Pellegrino, Elisa, Spaccarotella, Elisa, Lachel, Cynthia M., Kucuk, Can, Jiang, Chun-Sun, Hu, Xiaozhou, Bhagavathi, Sharathkumar, Greiner, Timothy C., Weisenburger, Dennis D., Aoun, Patricia, Perkins, Sherrie L., McKeithan, Timothy W., Inghirami, Giorgio, Chan, Wing C. ^*

Source: In Blood 19 September 2013 122(12):2083-2092

Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

Authors: Sindi, Hebah A., Russomanno, Giusy, Satta, Sandro, Abdul-Salam, Vahitha B., Jo, Kyeong Beom, Qazi-Chaudhry, Basma, Ainscough, Alexander J., Szulcek, Robert, Jan Bogaard, Harm, Morgan, Claire C., Pullamsetti, Soni S., Alzaydi, Mai M., Rhodes, Christopher J., Piva, Roberto, Eichstaedt, Christina A., Grünig, Ekkehard, Wilkins, Martin R., Wojciak-Stothard, Beata

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174626956.0x000001&indx=1&recIds=ETOCvdc_100174626956.0x000001

Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

Authors: Sindi, Hebah A., Russomanno, Giusy, Satta, Sandro, Abdul-Salam, Vahitha B., Jo, Kyeong Beom, Qazi-Chaudhry, Basma, Ainscough, Alexander J., Szulcek, Robert, Bogaard, Harm Jan, Morgan, Claire C., Pullamsetti, Soni S., Alzaydi, Mai M., Rhodes, Christopher J., Piva, Roberto, Eichstaedt, Christina A., Grünig, Ekkehard, Wilkins, Martin R., Wojciak-Stothard, Beata

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174569073.0x000001&indx=1&recIds=ETOCvdc_100174569073.0x000001

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

Authors: Agnelli, Luca ^*, Mereu, Elisabetta ^*, Pellegrino, Elisa, Limongi, Tania, Kwee, Ivo, Bergaggio, Elisa, Ponzoni, Maurilio, Zamò, Alberto, Iqbal, Javeed, Piccaluga, Pier Paolo, Neri, Antonino, Chan, Wing C., Pileri, Stefano, Bertoni, Francesco, Inghirami, Giorgio, Piva, Roberto

Source: In Blood 9 August 2012 120(6):1274-1281

Lentiviral vectors carrying enhancer elements of Hb9 promoter drive selective transgene expression in mouse spinal cord motor neurons

Authors: Peviani, Marco, Kurosaki, Mami, Terao, Mineko, Lidonnici, Dario, Gensano, Francesco, Battaglia, Elisa, Tortarolo, Massimo, Piva, Roberto, Bendotti, Caterina

Source: In Journal of Neuroscience Methods 30 March 2012 205(1):139-147

Essential Role of PDK1 in Regulating Endothelial Cell Migration

Authors: Primo, Luca, di Blasio, Laura, Roca, Cristina, Droetto, Sara, Piva, Roberto, Schaffhausen, Brian, Bussolino, Federico

Source: The Journal of Cell Biology, 2007 Mar . 176(7), 1035-1047.

Access URL: https://www.jstor.org/stable/30049839