Decreased expression of P-glycoprotein in the placenta of women with autoimmune disease

Authors: Pollinzi, Angela ¹, Mirdamadi, Kamelia ¹, Karimian Pour, Navaz ¹, Asthana-Nijjar, Rashi ¹, Lee, Dennis ², Nevo, Ori ², Piquette-Miller, Micheline ^{1, ∗}

Source: In Drug Metabolism and Disposition February 2025 53(2)

Altered Expression of BCRP Impacts Fetal Accumulation of Rosuvastatin in a Rat Model of Preeclampsia.

Authors: Dai, Wanying¹ (AUTHOR) wanying.dai@mail.utoronto.ca, Piquette-Miller, Micheline¹ (AUTHOR) m.piquette.miller@utoronto.ca

Source: Pharmaceutics. Jul2024, Vol. 16 Issue 7, p884. 11p.

Subject Terms: *PRENATAL drug exposure, *LABORATORY rats, *FETAL tissues, *ANIMAL disease models, *BREAST cancer, *PREECLAMPSIA

The Effect of Tobacco Use on the Expression of Placental Transporters in Alaska Native Women

Authors: McColl, Eliza R., Kwok, Jacinda, Benowitz, Neal L., Patten, Christi A., Hughes, Christine A., Koller, Kathryn R., Flanagan, Christie A., Thomas, Timothy K., Hiratsuka, Vanessa Y., Tyndale, Rachel F., Piquette‐Miller, Micheline

Source: Clinical pharmacology & therapeutics. 113(3):634-642

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175813743.0x000001&indx=1&recIds=ETOCvdc_100175813743.0x000001

Use of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of Preeclampsia

Authors: Dai, Wanying, Pollinzi, Angela, Piquette-Miller, Micheline ^*

Source: In Drug Metabolism and Disposition October 2023 51(10):1308-1315

COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics

Authors: McColl, Eliza R. ¹, Croyle, Maria A. ¹, Zamboni, William C. ¹, Honer, William G. ¹, Heise, Mark, Piquette-Miller, Micheline, Goralski, Kerry B. ^*

Source: In Drug Metabolism and Disposition January 2023 51(1):130-141

Regulation of Drug Transport Proteins—From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium

Authors: Brouwer, Kim L.R., Evers, Raymond, Hayden, Elizabeth, Hu, Shuiying, Li, Cindy Yanfei, Meyer zu Schwabedissen, Henriette E., Neuhoff, Sibylle, Oswald, Stefan, Piquette‐Miller, Micheline, Saran, Chitra, Sjöstedt, Noora, Sprowl, Jason A., Stahl, Simone H., Yue, Wei

Source: Clinical pharmacology & therapeutics. 112(3):461-484

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158381727.0x000001&indx=1&recIds=ETOCvdc_100158381727.0x000001

Impact of Inflammation and Infection on the Expression of Amino Acid Transporters in the Placenta: A Minireview

Authors: McColl, Eliza R., Hurtarte, Milena, Piquette-Miller, Micheline ^*

Source: In Drug Metabolism and Disposition September 2022 50(9):1251-1258

Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats

Authors: McColl, Eliza R., Piquette-Miller, Micheline

Source: In Placenta 1 September 2021 112:36-44

Dysregulation of renal transporters in a rodent model of viral Infection

Authors: Karimian Pour, Navaz, Piquette-Miller, Micheline

Source: In International Immunopharmacology March 2020 80

Essential role of STAT-3 dependent NF-κB activation on IL-6-mediated downregulation of hepatic transporters

Authors: Abualsunun, Walaa A., Sahin, Cigdem, Cummins, Carolyn L., Piquette-Miller, Micheline

Source: In European Journal of Pharmaceutical Sciences 15 February 2020 143

SLC Neurotransmitter Transporters as Therapeutic Targets for Alcohol Use Disorder: A Narrative Review

Authors: McColl, Eliza R., Piquette‐Miller, Micheline

Source: Alcoholism. 44(10):1965-1976

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108317876.0x000001&indx=1&recIds=ETOCvdc_100108317876.0x000001

Role of Elevated SFLT‐1 on the Regulation of Placental Transporters in Women With Pre‐Eclampsia

Authors: Kojovic, Dea, V. Workewych, Natalie, Piquette‐Miller, Micheline

Source: Clinical and translational science. 13(3):580-588

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107089656.0x000001&indx=1&recIds=ETOCvdc_100107089656.0x000001

Neurobiological Mechanisms of Chemotherapy-induced Cognitive Impairment in a Transgenic Model of Breast Cancer

Authors: Winocur, Gordon, Berman, Hal, Nguyen, Mary, Binns, Malcolm A., Henkelman, Mark, van Eede, Matthijs, Piquette-Miller, Micheline, Sekeres, Melanie J., Wojtowicz, J. Martin, Yu, Johnson, Zhang, Haibo, Tannock, Ian F.

Source: In Neuroscience 15 January 2018 369:51-65

The Age of Omics‐Driven Precision Medicine

Authors: McColl, Eliza R., Asthana, Rashi, Paine, Mary F., Piquette‐Miller, Micheline

Source: Clinical pharmacology & therapeutics. 106(3):477-481

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100109303972.0x000001&indx=1&recIds=ETOCvdc_100109303972.0x000001

Infection During Pregnancy Downregulates the Expression of Amino Acid Transporters in Rat and Human Placentas

Authors: McColl, Eliza R., Piquette‐Miller, Micheline

Source: FASEB journal. 36

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196490956.0x000001&indx=1&recIds=ETOCvdc_100196490956.0x000001

Downregulation of BCRP (ABCG2) in Placenta of Rat Model of Preeclampsia

Authors: Dai, Wanying, Piquette‐Miller, Micheline

Source: FASEB journal. 36

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196491062.0x000001&indx=1&recIds=ETOCvdc_100196491062.0x000001

Involvement of Nuclear Factor κB, not Pregnane X Receptor, in Inflammation-Mediated Regulation of Hepatic Transporters

Authors: Abualsunun, Walaa A., Piquette-Miller, Micheline ^*

Source: In Drug Metabolism and Disposition October 2017 45(10):1077-1083

Impact of endotoxin on the expression of drug transporters in the placenta of HIV-1 transgenic (HIV-Tg) rats

Authors: Ghoneim, Ragia H., Kojovic, Dea, Piquette-Miller, Micheline

Source: In European Journal of Pharmaceutical Sciences 1 May 2017 102:94-102

BRCA Status Does Not Predict Synergism of a Carboplatin and Olaparib Combination in High-Grade Serous Ovarian Cancer Cell Lines

Authors: Shen, Yen Ting, Evans, James C., Zafarana, Gaetano, Allen, Christine, Piquette-Miller, Micheline

Source: Molecular pharmaceutics. 15(7):2742-2753

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN616675252&indx=1&recIds=ETOCRN616675252

Ratio-Dependent Synergism of a Doxorubicin and Olaparib Combination in 2D and Spheroid Models of Ovarian Cancer

Authors: Eetezadi, Sina, Evans, James C., Shen, Yen-Ting, De Souza, Raquel, Piquette-Miller, Micheline, Allen, Christine

Source: Molecular pharmaceutics. 15(2):472-485

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN614835370&indx=1&recIds=ETOCRN614835370