Restriction of C1-inhibitor activity in hereditary angioedema by dominant-negative effects of disease-associated SERPING1 gene variants

Authors: Ryø, Laura Barrett, Haslund, Didde, Rovsing, Anne Bruun, Pihl, Rasmus, Sanrattana, Wariya, de Maat, Steven, Palarasah, Yaseelan, Maas, Coen, Thiel, Steffen, Mikkelsen, Jacob Giehm

Source: In The Journal of Allergy and Clinical Immunology November 2023 152(5):1218-1236

Inter-α-inhibitor heavy chain H4 and sepsis-related coagulation disturbances: Another link between innate immunity and coagulation

Authors: Larsen, Julie Brogaard, Pihl, Rasmus, Aggerbeck, Mathies Appel, Larsen, Kim Michael, Hvas, Christine Lodberg, Johnsen, Nanna, Christensen, Mette G., Praetorius, Helle, Hvas, Anne-Mette, Thiel, Steffen

Source: In Research and Practice in Thrombosis and Haemostasis February 2023 7(2)

A potent complement factor C3–specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement

Authors: Jensen, Rasmus K., Pihl, Rasmus, Gadeberg, Trine A.F., Jensen, Jan K., Andersen, Kasper R., Thiel, Steffen, Laursen, Nick S., Andersen, Gregers R.

Source: In Journal of Biological Chemistry 27 April 2018 293(17):6269-6281

Analysis of Factor D Isoforms in Malpuech—Michels—Mingarelli—Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement

Authors: Pihl, Rasmus, Jensen, Lisbeth, Hansen, Annette G., Thøgersen, Ida B., Andres, Stephanie, Dagnæs-Hansen, Frederik, Oexle, Konrad, Enghild, Jan J., Thiel, Steffen

Source: Journal of immunology. 199(6):2158-2170

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612849503&indx=1&recIds=ETOCRN612849503

Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement

Authors: Jensen, Rasmus K., Pihl, Rasmus, Gadeberg, Trine A.F., Jensen, Jan K., Andersen, Kasper R., Thiel, Steffen, Laursen, Nick S., Andersen, Gregers R.

Source: In Journal of Biological Chemistry February 2023 299(2)

Nature-inspired protein ligation and its applications.

Authors: Pihl, Rasmus, Zheng, Qingfei, David, Yael

Source: Nature Reviews Chemistry; Apr2023, Vol. 7 Issue 4, p234-255, 22p

ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism.

Authors: Pihl, Rasmus¹, Jensen, Rasmus K.², Poulsen, Emil C.², Jensen, Lisbeth¹, Hansen, Annette G.¹, Thøgersen, Ida B.², Dobó, József³, Gál, Péter³, Andersen, Gregers R.², Enghild, Jan J.², Thiel, Steffen¹ st@biomed.au.dk

Source: Science Advances. Jan2021, Vol. 7 Issue 2, p1-17. 17p.

Subject Terms: *LECTINS, *PROTEASE inhibitors, *ELASTASES, *COMPLEMENT receptors, *BLOOD proteins

Protease inhibitor plasma concentrations associate with COVID-19 infection.

Authors: Medjeral-Thomas, Nicholas R, Troldborg, Anne, Hansen, Annette G, Pihl, Rasmus, Clarke, Candice L, Peters, James E, Thomas, David C, Willicombe, Michelle, Palarasah, Yaseelan, Botto, Marina, Pickering, Matthew C, Thiel, Steffen

Source: Oxford Open Immunology; 2021, Vol. 2 Issue 1, p1-7, 7p

Subject Terms: PROTEASE inhibitors, COVID-19, ATAZANAVIR, BLOOD proteins, C-reactive protein, HEMODIALYSIS patients

Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D.

Authors: Holers, V. Michael, Borodovsky, Anna, Scheinman, Robert I., Ho, Nhu, Ramirez, Joseline Ramos, Dobó, József, Gál, Péter, Lindenberger, Jared, Hansen, Annette G., Desai, Dhruv, Pihl, Rasmus, Thiel, Steffen, Banda, Nirmal K.

Source: Frontiers in Immunology; 2/21/2020, p1-18, 18p

Subject Terms: TRANSCRIPTION factors, SERINE proteinases, ARTHRITIS, PATHOLOGY, RHEUMATOID arthritis

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A novel nanobody inhibitor of the alternative pathway

Authors: Jensen, Rasmus Kjeldsen, Pihl, Rasmus, Laursen, Nick Stub, Thiel, Steffen, Andersen, Gregers Rom

Source: In Molecular Immunology September 2017 89:198-198

Analysis of Factor D isoforms in 3MC patients highlights the role of MASP-3 as a maturase in the alternative pathway of complement

Authors: Pihl, Rasmus, Jensen, Lisbeth, Hansen, Annette G., Thiel, Steffen

Source: In Molecular Immunology September 2017 89:144-144

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Investigation of the role of MASP-3 in the alternative pathway through a new technique for examining the conversion of pro-factor D to factor D

Authors: Pihl, Rasmus, Jensen, Lisbeth, Jensenius, Jens Christian, Thiel, Steffen

Source: In Immunobiology October 2016 221(10):1220-1220