Dynamics of SERPINA3 in response to anthracycline treatment and cardiovascular dysfunction

Authors: Hanne M. Boen, Lobke L. Pype, Konstantinos Papadimitriou, Sevilay Altintas, Laure-Anne Teuwen, Sébastien Anguille, Kirsten Saevels, Anke Verlinden, Leen Delrue, Ward A. Heggermont, Matthias Bosman, Pieter-Jan Guns, Hein Heidbuchel, Caroline M. Van De Heyning, Emeline M. Van Craenenbroeck, Constantijn Franssen

Source: Cardio-Oncology, Vol 11, Iss 1, Pp 1-13 (2025)

Subject Terms: Cancer therapy-related cardiac dysfunction (CTRCD), SERPINA3, Cardiotoxicity, Biomarker, Anthracycline, Breast cancer, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/7df43c30a7364c1a9910cb12320980e9

Acute vascular and cardiac effects of lenvatinib in mice

Authors: Dustin N. Krüger, Patrizia Pannucci, Callan D. Wesley, Cedric H. G. Neutel, Wim Martinet, Guido R. Y. De Meyer, Stephen J. Hill, Jeanette Woolard, Constantijn Franssen, Pieter-Jan Guns

Source: Cardio-Oncology, Vol 11, Iss 1, Pp 1-13 (2025)

Subject Terms: Hypertension, TKIs, VEGFR, Cardiovascular toxicity, ATP, Lenvatinib, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/2533ec81903c47099ce5dabc57f622c5

Calciprotein particles induce arterial stiffening ex vivo and impair vascular cell function

Authors: Cédric H. G. Neutel, Callan D. Wesley, Cindy van Loo, Céline Civati, Freke Mertens, Michelle Zurek, Anja Verhulst, Isabel Pintelon, Winnok H. De Vos, Bart Spronck, Lynn Roth, Guido R. Y. De Meyer, Wim Martinet, Pieter-Jan Guns

Source: Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/ec219c4be4484da5ac08fecee8cd9237

Dexrazoxane prevents vascular toxicity in doxorubicin-treated mice

Authors: Dustin N. Krüger, Matthias Bosman, Emeline M. Van Craenenbroeck, Guido R. Y. De Meyer, Constantijn Franssen, Pieter-Jan Guns

Source: Cardio-Oncology, Vol 10, Iss 1, Pp 1-11 (2024)

Subject Terms: Doxorubicin, Dexrazoxane, Vascular toxicity, Endothelial cell dysfunction, SERPINA3, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/56a98f05017b45b4b30d87d48e86a2eb

Unravelling the impact of active and passive contributors to arterial stiffness in male mice and their role in vascular aging

Authors: Callan D. Wesley, Cedric H. G. Neutel, Guido R. Y. De Meyer, Wim Martinet, Pieter-Jan Guns

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8d61bd1c723b4cf8931c209ee6c633a5

The influence of endurance exercise training on myocardial fibrosis and arrhythmogenesis in a coxsackievirus B3 myocarditis mouse model

Authors: Kasper Favere, Manon Van Hecke, Sander Eens, Matthias Bosman, Peter L. Delputte, Johan De Sutter, Erik Fransen, Tania Roskams, Pieter-Jan Guns, Hein Heidbuchel

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)

Subject Terms: Viral myocarditis, Exercise, Myocardial fibrosis, Scarring, Inflammation, Arrhythmogenesis, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a3aa50b2b3c344d78c2eef5c5072f2b5

Characterization of systolic and diastolic function, alongside proteomic profiling, in doxorubicin-induced cardiovascular toxicity in mice

Authors: Dustin N. Krüger, Matthias Bosman, Charles X.L. Van Assche, Callan D. Wesley, Berta Cillero-Pastor, Leen Delrue, Ward Heggermont, Jozef Bartunek, Guido R. Y. De Meyer, Emeline M. Van Craenenbroeck, Pieter-Jan Guns, Constantijn Franssen

Source: Cardio-Oncology, Vol 10, Iss 1, Pp 1-17 (2024)

Subject Terms: Doxorubicin, Cardiovascular toxicity, Serpina3, Diastolic dysfunction, Heart failure, Biomarker, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/be96370b15b24456a6a68e11cd636233

Short-Term Proteasome Inhibition: Assessment of the Effects of Carfilzomib and Bortezomib on Cardiac Function, Arterial Stiffness, and Vascular Reactivity

Authors: Callan D. Wesley, Annarita Sansonetti, Cedric H. G. Neutel, Dustin N. Krüger, Guido R. Y. De Meyer, Wim Martinet, Pieter-Jan Guns

Source: Biology, Vol 13, Iss 10, p 844 (2024)

Subject Terms: arterial stiffness, vascular reactivity, cardiac function, proteasome inhibitors, bortezomib, carfilzomib, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/13/10/844; https://doaj.org/toc/2079-7737

Access URL: https://doaj.org/article/47630c895e1d4d558ebbda20a048bc49

Increasing pulse pressure ex vivo, mimicking acute physical exercise, induces smooth muscle cell-mediated de-stiffening of murine aortic segments

Authors: Cédric H. G. Neutel, Anne-Sophie Weyns, Arthur Leloup, Sofie De Moudt, Pieter-Jan Guns, Paul Fransen

Source: Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/c6d9b715d9b64dafb0ef9713c76d8557

Endurance Exercise Does Not Exacerbate Cardiac Inflammation in BALB/c Mice Following mRNA COVID-19 Vaccination

Authors: Sander Eens, Manon Van Hecke, Siel Van den Bogaert, Kasper Favere, Nathalie Cools, Erik Fransen, Tania Roskams, Hein Heidbuchel, Pieter-Jan Guns

Source: Vaccines, Vol 12, Iss 9, p 966 (2024)

Subject Terms: myocarditis, myopericarditis, mRNA vaccine, BNT162b2, endurance exercise, exercise, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/9/966; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/838b2e3215fa4ad4a9323250be1bd9b8

Molecular mechanisms of post‐burn muscle wasting and the therapeutic potential of physical exercise

Authors: Dorien Dombrecht, Ulrike Van Daele, Birgit Van Asbroeck, David Schieffelers, Pieter‐Jan Guns, Nick Gebruers, Jill Meirte, Eric vanBreda

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 758-770 (2023)

Subject Terms: Burns, Muscle wasting, Cachexia, Exercise, Signalling pathways, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/f5f0f5bf22ec4608a1674396f653015d

Addendum: B-cell lymphoblastic lymphoma following intravenous BNT162b2 mRNA booster in a BALB/c mouse: a case report

Authors: Sander Eens, Manon Van Hecke, Kasper Favere, Thomas Tousseyn, Pieter-Jan Guns, Tania Roskams, Hein Heidbuchel

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: lymphoma, B-cell, lymphoblastic, COVID-19, mRNA vaccine, BNT162b2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1267904/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/2a1efb8ea41b44a7a11de01b418af35b

The effect of cyclic stretch on aortic viscoelasticity and the putative role of smooth muscle focal adhesion

Authors: Cédric H. G. Neutel, Callan D. Wesley, Guido R. Y. De Meyer, Wim Martinet, Pieter-Jan Guns

Source: Frontiers in Physiology, Vol 14 (2023)

Subject Terms: viscoelasticity, aorta, vascular smooth muscle cell, focal adhesion, cyclic stretch, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2023.1218924/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/683eb2058dc74387803314d873822cd9

B-cell lymphoblastic lymphoma following intravenous BNT162b2 mRNA booster in a BALB/c mouse: A case report

Authors: Sander Eens, Manon Van Hecke, Kasper Favere, Thomas Tousseyn, Pieter-Jan Guns, Tania Roskams, Hein Heidbuchel

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: lymphoma, B-cell, lymphoblastic, COVID-19, mRNA vaccine, BNT162b2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1158124/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/0a16c51941f0409cb28c346b1eb41c3d

Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?

Authors: Magy Sallam, Mohammed Abderrafi Benotmane, Sarah Baatout, Pieter-Jan Guns, An Aerts

Source: Epigenetics, Vol 17, Iss 1, Pp 59-80 (2022)

Subject Terms: radiation, cardiovascular disease, epigenetics, dna methylation, breast cancer, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/4dd9a80ac1d04828aabed22c25998ae7

Dexrazoxane does not mitigate early vascular toxicity induced by doxorubicin in mice

Authors: Matthias Bosman, Dustin N. Krüger, Kasper Favere, Guido R. Y. De Meyer, Constantijn Franssen, Emeline M. Van Craenenbroeck, Pieter-Jan Guns

Source: PLoS ONE, Vol 18, Iss 11 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684076/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/da5c8b0dd0294d69a5b2258ec791f609

High Pulsatile Load Decreases Arterial Stiffness: An ex vivo Study

Authors: Cédric H. G. Neutel, Giulia Corradin, Pauline Puylaert, Guido R. Y. De Meyer, Wim Martinet, Pieter-Jan Guns

Source: Frontiers in Physiology, Vol 12 (2021)

Subject Terms: pulse pressure, arterial stiffness, biomechanics, infrarenal aorta, thoracic descending aorta, VSMC, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.741346/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/4057e966492e45248f6631ee68eb6d21

Harmonization of Brain Diffusion MRI: Concepts and Methods

Authors: Maíra Siqueira Pinto, Roberto Paolella, Thibo Billiet, Pieter Van Dyck, Pieter-Jan Guns, Ben Jeurissen, Annemie Ribbens, Arnold J. den Dekker, Jan Sijbers

Source: Frontiers in Neuroscience, Vol 14 (2020)

Subject Terms: harmonization, normalization, diffusion MRI, multi-site, inter-scanner, review, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnins.2020.00396/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/9ded15a2b14147b3a575ce833d8a7b27

Gasdermin D Deficiency Limits the Transition of Atherosclerotic Plaques to an Inflammatory Phenotype in ApoE Knock-Out Mice

Authors: Pauline Puylaert, Melissa Van Praet, Frederik Vaes, Cédric H. G. Neutel, Lynn Roth, Pieter-Jan Guns, Guido R. Y. De Meyer, Wim Martinet

Source: Biomedicines, Vol 10, Iss 5, p 1171 (2022)

Subject Terms: gasdermin D, pyroptosis, inflammation, atherosclerosis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/5/1171; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/18ea2978b0f34161b7e274ce89d7fbfe

The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach

Authors: Pauline Puylaert, Isabelle Coornaert, Cédric H. G. Neutel, Yves Dondelinger, Tom Delanghe, Mathieu J. M. Bertrand, Pieter-Jan Guns, Guido R. Y. De Meyer, Wim Martinet

Source: Biomedicines, Vol 10, Iss 5, p 1016 (2022)

Subject Terms: RIPK1, atherosclerosis, necroptosis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/5/1016; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/6ae2ec87e37a4839b532198be7d67cc8