Cyclin-dependent kinases and rare developmental disorders

Authors: Pierre Colas

Source: Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-14 (2020)

Subject Terms: CDKs, Cyclins, Developmental disorders, Regulatory networks, Interaction profiling, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13023-020-01472-y; https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/de154202240d42908abbe8b4b447c5fd

Functional characterization of CDK10 and cyclin M truncated variants causing severe developmental disorders

Authors: Thomas Robert, Anne‐Catherine Dock‐Bregeon, Pierre Colas

Source: Molecular Genetics & Genomic Medicine, Vol 9, Iss 10, Pp n/a-n/a (2021)

Subject Terms: Al Kaissi syndrome, CDK10, cyclin M, interaction profiling, protein kinase, STAR syndrome, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/a9b71a335ec247d798d8c68cdf527e63

Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors

Authors: Thomas Robert, Jared L. Johnson, Roxane Guichaoua, Tomer M. Yaron, Stéphane Bach, Lewis C. Cantley, Pierre Colas

Source: Frontiers in Chemistry, Vol 8 (2020)

Subject Terms: CDK10, Cyclin M, CDK10tide, screening assay, kinase inhibitors, NVP-2, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fchem.2020.00147/full; https://doaj.org/toc/2296-2646

Access URL: https://doaj.org/article/035492ef7e2b4e65b050f4fe659638a0

Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi

Authors: Thi-Ngoc-Dung Nguyen, Omid Feizbakhsh, Estelle Sfecci, Blandine Baratte, Claire Delehouzé, Adrien Garcia, Corentin Moulin, Pierre Colas, Sandrine Ruchaud, Mohamed Mehiri, Stéphane Bach

Source: Marine Drugs, Vol 17, Iss 10, p 569 (2019)

Subject Terms: screening, kinase inhibition, regulated cell death, rip1-independent cell death, marine natural products, crambe tailliezi, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1660-3397/17/10/569; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/efe9d9089528481dabd378f52d0fc097

A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death.

Authors: Perayot Pamonsinlapatham, Réda Hadj-Slimane, Françoise Raynaud, Marc Bickle, Claudine Corneloup, Audrey Barthelaix, Yves Lepelletier, Perrine Mercier, Matthieu Schapira, Jérôme Samson, Anne-Laure Mathieu, Nicolas Hugo, Olivier Moncorgé, Ivan Mikaelian, Sylvie Dufour, Christiane Garbay, Pierre Colas

Source: PLoS ONE, Vol 3, Iss 8, p e2902 (2008)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2483412?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e97a2dabf7aa4f3a9ac24b82b69a64bb

Pyrazolo[1,5-a]-1,3,5-triazine as a Purine Bioisostere: Access to Potent Cyclin-Dependent Kinase Inhibitor (R)-Roscovitine Analogue.

Authors: Florence Popowycz, Guy Fournet, Cédric Schneider, Karima Bettayeb, Yoan Ferandin, Cyrile Lamigeon, Oscar M. Tirado, Silvia Mateo-Lozano, Vicente Notario, Pierre Colas, Philippe Bernard, Laurent Meijer, Benoît Joseph

Source: Journal of Medicinal Chemistry; Feb2009, Vol. 52 Issue 3, p655-663, 9p