Ribes nigrum leaf extract downregulates pro-inflammatory gene expression and regulates redox balance in microglial cells

Authors: Alvard Minasyan, Vivien Pires, Catherine Gondcaille, Mikayel Ginovyan, Marika Mróz, Stéphane Savary, Mustapha Cherkaoui-Malki, Barbara Kusznierewicz, Agnieszka Bartoszek, Pierre Andreoletti, Naira Sahakyan

Source: BMC Complementary Medicine and Therapies, Vol 25, Iss 1, Pp 1-17 (2025)

Subject Terms: Oxidative stress, Armenian flora, Reactive oxygen species, Polyphenols, Neurodegenerative disorders, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/1f7854218b474227a32570fff04e1830

Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes

Authors: Ali Tawbeh, Catherine Gondcaille, Fatima-Ezzahra Saih, Quentin Raas, Damien Loichot, Yannick Hamon, Céline Keime, Alexandre Benani, Francesca Di Cara, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Stéphane Savary

Source: Frontiers in Molecular Neuroscience, Vol 18 (2025)

Subject Terms: neuroinflammation, peroxisome, microglia, oxidative stress, reactive oxygen species, nitric oxide, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2025.1542938/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/d22caaa2b6904199bda6872325260a1f

Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation

Authors: Ali Tawbeh, Quentin Raas, Mounia Tahri-Joutey, Céline Keime, Romain Kaiser, Doriane Trompier, Boubker Nasser, Emma Bellanger, Marie Dessard, Yannick Hamon, Alexandre Benani, Francesca Di Cara, Tânia Cunha Alves, Johannes Berger, Isabelle Weinhofer, Stéphane Mandard, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Catherine Gondcaille, Stéphane Savary

Source: Frontiers in Molecular Neuroscience, Vol 16 (2023)

Subject Terms: adrenoleukodystrophy, antigen presentation, immune response, inflammation, microglia, peroxisome, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2023.1299314/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/911be27ef95548c485aa7100b731715f

Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract

Authors: Mikayel Ginovyan, Agnieszka Bartoszek, Izabela Koss-Mikołajczyk, Barbara Kusznierewicz, Pierre Andreoletti, Mustapha Cherkaoui-Malki, Naira Sahakyan

Source: AIMS Biophysics, Vol 9, Iss 3, Pp 282-293 (2022)

Subject Terms: plant extract, armenian flora, cytotoxicity, microglia, human adenocarcinoma, breast cancer, Biology (General), QH301-705.5, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/2377-9098

Access URL: https://doaj.org/article/ee455e5e3e224717ac09f07c1599fb5c

The Potential Role of Major Argan Oil Compounds as Nrf2 Regulators and Their Antioxidant Effects

Authors: Riad El Kebbaj, Habiba Bouchab, Mounia Tahri-Joutey, Soufiane Rabbaa, Youness Limami, Boubker Nasser, Melford C. Egbujor, Paolo Tucci, Pierre Andreoletti, Luciano Saso, Mustapha Cherkaoui-Malki

Source: Antioxidants, Vol 13, Iss 3, p 344 (2024)

Subject Terms: argan oil, Nrf2, tocopherols, polyphenols, fatty acids, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/3/344; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/04afcec45d9a4e198d9572a62efd946b

Hypericum alpestre extract affects the activity of the key antioxidant enzymes in microglial BV-2 cellular models

Authors: Mikayel Ginovyan, Pierre Andreoletti, Mustapha Cherkaoui-Malki, Naira Sahakyan

Source: AIMS Biophysics, Vol 9, Iss 2, Pp 161-171 (2022)

Subject Terms: plant extract, armenian flora, total phenolic content, hypericaceae, antioxidant enzymes, microglia, Biology (General), QH301-705.5, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/2377-9098

Access URL: https://doaj.org/article/c3cd0634e18f41319866a634eb82cc2f

Peroxisomal defects in microglial cells induce a disease-associated microglial signature

Authors: Quentin Raas, Ali Tawbeh, Mounia Tahri-Joutey, Catherine Gondcaille, Céline Keime, Romain Kaiser, Doriane Trompier, Boubker Nasser, Valerio Leoni, Emma Bellanger, Maud Boussand, Yannick Hamon, Alexandre Benani, Francesca Di Cara, Caroline Truntzer, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Stéphane Savary

Source: Frontiers in Molecular Neuroscience, Vol 16 (2023)

Subject Terms: peroxisome, adrenoleukodystrophy (X-ALD), microglia, lysosome, lipid metabolism, autophagy, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2023.1170313/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/e61fd3afe1cd4f0d9a7144d4fea8bc3c

Antioxidant Effects of Argan Oil and Olive Oil against Iron-Induced Oxidative Stress: In Vivo and In Vitro Approaches

Authors: Habiba Bouchab, Soukaina Essadek, Soufiane El Kamouni, Khadija Moustaid, Abdelkhalid Essamadi, Pierre Andreoletti, Mustapha Cherkaoui-Malki, Riad El Kebbaj, Boubker Nasser

Source: Molecules, Vol 28, Iss 15, p 5924 (2023)

Subject Terms: oxidative stress, antioxidant enzymes, ferrous sulfate, argan oil, olive oil, brain, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/15/5924; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/a7dc31fd89254f2c9ae8e20a2e0ea061

Two Argan Oil Phytosterols, Schottenol and Spinasterol, Attenuate Oxidative Stress and Restore LPS-Dysregulated Peroxisomal Functions in Acox1−/− and Wild-Type BV-2 Microglial Cells

Authors: Soukaina Essadek, Catherine Gondcaille, Stéphane Savary, Mohammad Samadi, Joseph Vamecq, Gérard Lizard, Riad El Kebbaj, Norbert Latruffe, Alexandre Benani, Boubker Nasser, Mustapha Cherkaoui-Malki, Pierre Andreoletti

Source: Antioxidants, Vol 12, Iss 1, p 168 (2023)

Subject Terms: Acyl-CoA oxidase 1, argan oil, BV-2, catalase, inflammation, LPS, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/1/168; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/86aa25f10d78404b8c831e4bbfcb5f05

Cytoprotective organoselenium compounds for oligodendrocytes

Authors: Saad Shaaban, Amira Zarrouk, Dominique Vervandier-Fasseur, Yasair S.Al-Faiyz, Hany El-Sawy, Ismail Althagafi, Pierre Andreoletti, Mustapha Cherkaoui-Malki

Source: Arabian Journal of Chemistry, Vol 14, Iss 4, Pp 103051- (2021)

Subject Terms: Organoselenium, Ugi reaction, Tetrazole, Antioxidant, Oligodendrocytes, Cytoprotective, Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1878535221000666; https://doaj.org/toc/1878-5352

Access URL: https://doaj.org/article/09f95b8a70e54b9997e542b8e47f7b73

Effects of a Short-Term Lipopolysaccharides Challenge on Mouse Brain and Liver Peroxisomal Antioxidant and β-oxidative Functions: Protective Action of Argan Oil

Authors: Soukaina Essadek, Habiba Bouchab, Riad El Kebbaj, Catherine Gondcaille, Soufiane El Kamouni, Stéphane Savary, Joseph Vamecq, Abdelkhalid Essamadi, Mustapha Cherkaoui-Malki, Boubker Nasser, Pierre Andreoletti

Source: Pharmaceuticals, Vol 15, Iss 4, p 465 (2022)

Subject Terms: argan oil, antioxidant, Acyl-CoA oxidase 1, brain, beta-oxidation, catalase, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/4/465; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/1779c4e53f084d1caafb16a3c04b9d45

Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells

Authors: Fatiha Brahmi, Samia Hadj-Ahmed, Amira Zarrouk, Maryem Bezine, Thomas Nury, Khodir Madani, Mohamed Chibane, Anne Vejux, Pierre Andreoletti, Lila Boulekbache-Makhlouf, Gérard Lizard

Source: Pharmaceutical Biology, Vol 55, Iss 1, Pp 286-293 (2017)

Subject Terms: mentha spicata, mentha pulegium, mentha rotundifolia, mitochondria, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1388-0209; https://doaj.org/toc/1744-5116

Access URL: https://doaj.org/article/dde210eac01744b5bcda1cf4a5e478dd

Nopal Cactus (Opuntia ficus-indica) as a Source of Bioactive Compounds for Nutrition, Health and Disease

Authors: Karym El-Mostafa, Youssef El Kharrassi, Asmaa Badreddine, Pierre Andreoletti, Joseph Vamecq, M'Hammed Saïd El Kebbaj, Norbert Latruffe, Gérard Lizard, Boubker Nasser, Mustapha Cherkaoui-Malki

Source: Molecules, Vol 19, Iss 9, Pp 14879-14901 (2014)

Subject Terms: anti-inflammatory, antioxidants, cell signaling, Opuntia ficus-indica, polyphenols, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/19/9/14879; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/3c8db6b9f6774fc39e0f5c1146110f98

Cytoprotective and Antioxidants in Peroxisomal Neurodegenerative Diseases

Authors: Mustapha Cherkaoui-Malki, Saad Shaaban, Mounia Tahri-Joutey, Ahmed Elshobaky, Fatima-Ezzahra Saih, Dominique Vervandier-Fasseur, Claus Jacob, Boubker Nasser, Norbert Latruffe, Pierre Andreoletti

Source: Proceedings, Vol 11, Iss 1, p 33 (2019)

Subject Terms: antioxidant, leukodystrophy, organoselenides, peroxisome, resveratrol, General Works

File Description: electronic resource

Relation: https://www.mdpi.com/2504-3900/11/1/33; https://doaj.org/toc/2504-3900

Access URL: https://doaj.org/article/bde9011027b443fca655154d567b83cd

Sox17 regulates liver lipid metabolism and adaptation to fasting.

Authors: Samuel Rommelaere, Virginie Millet, Thien-Phong Vu Manh, Thomas Gensollen, Pierre Andreoletti, Mustapha Cherkaoui-Malki, Christophe Bourges, Bertrand Escalière, Xin Du, Yu Xia, Jean Imbert, Bruce Beutler, Yoshiakira Kanai, Bernard Malissen, Marie Malissen, Anne Tailleux, Bart Staels, Franck Galland, Philippe Naquet

Source: PLoS ONE, Vol 9, Iss 8, p e104925 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4139292?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3705feadd8e34ffe926cda44baea63d0

Protective Effect of Cactus Cladode Extracts on Peroxisomal Functions in Microglial BV-2 Cells Activated by Different Lipopolysaccharides

Authors: Fatima-Ezzahra Saih, Pierre Andreoletti, Stéphane Mandard, Norbert Latruffe, M’Hammed Saïd El Kebbaj, Gérard Lizard, Boubker Nasser, Mustapha Cherkaoui-Malki

Source: Molecules, Vol 22, Iss 1, p 102 (2017)

Subject Terms: acyl-CoA oxidase 1, catalase, β-oxidation, Escherichia coli, lipopolysaccharides, LPS, nitric oxide, Opuntia, peroxisomes, Salmonella minnesota, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/22/1/102; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/9d2f5adb166741c8b6577c75d889f462