Vaginal Lactobacillus fatty acid response mechanisms reveal a metabolite-targeted strategy for bacterial vaginosis treatment

Authors: Zhu, Meilin, Frank, Matthew W., Radka, Christopher D., Jeanfavre, Sarah, Xu, Jiawu, Tse, Megan W., Pacheco, Julian Avila, Kim, Jae Sun, Pierce, Kerry, Deik, Amy, Hussain, Fatima Aysha, Elsherbini, Joseph, Hussain, Salina, Xulu, Nondumiso, Khan, Nasreen, Pillay, Vanessa, Mitchell, Caroline M., Dong, Krista L., Ndung'u, Thumbi, Clish, Clary B., Rock, Charles O., Blainey, Paul C., Bloom, Seth M., Kwon, Douglas S.

Source: In Cell 19 September 2024 187(19):5413-5430

Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course

Authors: Schirmer, Melanie, Stražar, Martin, Avila-Pacheco, Julian, Rojas-Tapias, Daniel F., Brown, Eric M., Temple, Emily, Deik, Amy, Bullock, Kevin, Jeanfavre, Sarah, Pierce, Kerry, Jin, Shen, Invernizzi, Rachele, Pust, Marie-Madlen, Costliow, Zach, Mack, David R., Griffiths, Anne M., Walters, Thomas, Boyle, Brendan M., Kugathasan, Subra, Vlamakis, Hera, Hyams, Jeffrey, Denson, Lee, Clish, Clary B., Xavier, Ramnik J.

Source: In Cell Host & Microbe 14 February 2024 32(2):209-226

A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning

Authors: Vatanen, Tommi, Ang, Qi Yan, Siegwald, Léa, Sarker, Shafiqul Alam, Le Roy, Caroline I., Duboux, Stéphane, Delannoy-Bruno, Omar, Ngom-Bru, Catherine, Boulangé, Claire L., Stražar, Martin, Avila-Pacheco, Julian, Deik, Amy, Pierce, Kerry, Bullock, Kevin, Dennis, Courtney, Sultana, Shamima, Sayed, Sharika, Rahman, Mahbubar, Ahmed, Tahmeed, Modesto, Monica, Mattarelli, Paola, Clish, Clary B., Vlamakis, Hera, Plichta, Damian R., Sakwinska, Olga, Xavier, Ramnik J.

Source: In Cell 10 November 2022 185(23):4280-4297

Acetaminophen Use in Pregnancy: A Comparison of Self-Reported Intake with Maternal and Newborn Biomarker Measures.

Authors: Guo, Pengfei, Johnson, Caroline H, Yan, Hong, Xiao, Jingyuan, Dennis, Courtney, Pierce, Kerry A, DeWan, Andrew T, Liew, Zeyan

Source: Clinical Epidemiology; Jan2025, Vol. 17, p1-6, 6p

Tricarboxylic acid cycle related-metabolites and risk of atrial fibrillation and heart failure

Authors: Bulló, Mònica, Papandreou, Christopher, García-Gavilán, Jesus, Ruiz-Canela, Miguel, Li, Jun, Guasch-Ferré, Marta, Toledo, Estefanía, Clish, Clary, Corella, Dolores, Estruch, Ramon, Ros, Emilio, Fitó, Montserrat, Lee, Chih-Hao, Pierce, Kerry, Razquin, Cristina, Arós, Fernando, Serra-Majem, Lluís, Liang, Liming, Martínez-González, Miguel A., Hu, Frank B., Salas-Salvadó, Jordi

Source: In Metabolism December 2021 125

Metabolic modeling of single Th17 cells reveals regulators of autoimmunity

Authors: Wagner, Allon, Wang, Chao, Fessler, Johannes, DeTomaso, David, Avila-Pacheco, Julian, Kaminski, James, Zaghouani, Sarah, Christian, Elena, Thakore, Pratiksha, Schellhaass, Brandon, Akama-Garren, Elliot, Pierce, Kerry, Singh, Vasundhara, Ron-Harel, Noga, Douglas, Vivian Paraskevi, Bod, Lloyd, Schnell, Alexandra, Puleston, Daniel, Sobel, Raymond A., Haigis, Marcia, Pearce, Erika L., Soleimani, Manoocher, Clish, Clary, Regev, Aviv, Kuchroo, Vijay K., Yosef, Nir

Source: In Cell 5 August 2021 184(16):4168-4185

Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features

Authors: Madison, Jon M., Duong, Karen, Vieux, Ellen F., Udeshi, Namrata D., Iqbal, Sumaiya, Requadt, Elise, Fereshetian, Shaunt, Lewis, Michael C., Gomes, Antonio S., Pierce, Kerry A., Platt, Randall J., Zhang, Feng, Campbell, Arthur J., Lal, Dennis, Wagner, Florence F., Clish, Clary B., Carr, Steven A., Sheng, Morgan, Scolnick, Edward M., Cottrell, Jeffrey R.

Source: In iScience 22 January 2021 24(1)

Physical performance and plasma metabolic profile as potential prognostic factors in metastatic lung cancer patients.

Authors: das Neves, Willian, Alves, Christiano R. R., dos Santos, Gabriela, Alves, Maria‐Janieire N. N., Deik, Amy, Pierce, Kerry, Dennis, Courtney, Buckley, Lily, Clish, Clary B., Swoboda, Kathryn J., Brum, Patricia C., de Castro Junior, Gilberto

Source: European Journal of Clinical Investigation; Nov2024, Vol. 54 Issue 11, p1-13, 13p

Subject Terms: PHYSICAL mobility, BODY composition, OVERALL survival, MUSCLE metabolism, LUNG cancer

Glycolysis/gluconeogenesis- and tricarboxylic acid cycle–related metabolites, Mediterranean diet, and type 2 diabetes

Authors: Guasch-Ferré, Marta, Santos, José L, Martínez-González, Miguel A, Clish, Clary B, Razquin, Cristina, Wang, Dong, Liang, Liming, Li, Jun, Dennis, Courtney, Corella, Dolores, Muñoz-Bravo, Carlos, Romaguera, Dora, Estruch, Ramón, Santos-Lozano, José Manuel, Castañer, Olga, Alonso-Gómez, Angel, Serra-Majem, Luis, Ros, Emilio, Canudas, Sílvia, Asensio, Eva M, Fitó, Montserrat, Pierce, Kerry, Martínez, J Alfredo, Salas-Salvadó, Jordi, Toledo, Estefanía, Hu, Frank B, Ruiz-Canela, Miguel ^*

Source: In The American Journal of Clinical Nutrition April 2020 111(4):835-844

Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney

Authors: Simic, Petra, Kim, Wondong, Zhou, Wen, Pierce, Kerry A., Chang, Wenhan, Sykes, David B., Aziz, Najihah B., Elmariah, Sammy, Ngo, Debby, Pajevic, Paola Divieti

Source: Journal of clinical investigation. 130(3):1513-1526

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623253841&indx=1&recIds=ETOCRN623253841

Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community

Authors: Nayor, Matthew, Shah, Ravi V., Miller, Patricia E., Blodgett, Jasmine B., Tanguay, Melissa, Pico, Alexander R., Murthy, Venkatesh L., Malhotra, Rajeev, Houstis, Nicholas E., Deik, Amy, Pierce, Kerry A., Bullock, Kevin, Dailey, Lucas, Velagaleti, Raghava S., Moore, Stephanie A., Ho, Jennifer E., Baggish, Aaron L., Clish, Clary B., Larson, Martin G., Vasan, Ramachandran S., Lewis, Gregory D.

Source: Circulation. 142(20):1905-1924

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150445905.0x000001&indx=1&recIds=ETOCvdc_100150445905.0x000001

Commensal consortia decolonize Enterobacteriaceae via ecological control.

Authors: Furuichi, Munehiro, Kawaguchi, Takaaki, Pust, Marie-Madlen, Yasuma-Mitobe, Keiko, Plichta, Damian R., Hasegawa, Naomi, Ohya, Takashi, Bhattarai, Shakti K., Sasajima, Satoshi, Aoto, Yoshimasa, Tuganbaev, Timur, Yaginuma, Mizuki, Ueda, Masahiro, Okahashi, Nobuyuki, Amafuji, Kimiko, Kiridoshi, Yuko, Sugita, Kayoko, Stražar, Martin, Avila-Pacheco, Julian, Pierce, Kerry

Source: Nature; Sep2024, Vol. 633 Issue 8031, p878-886, 9p

Early loss of mitochondrial complex I and rewiring of glutathione metabolism in renal oncocytoma

Authors: Gopal, Raj K., Calvo, Sarah E., Shih, Angela R., Chaves, Frances L., McGuone, Declan, Mick, Eran, Pierce, Kerry A., Li, Yang, Garofalo, Andrea, Van Allen, Eliezer M., Clish, Clary B., Oliva, Esther, Mootha, Vamsi K.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Jul 01. 115(27), E6283-E6290.

Access URL: https://www.jstor.org/stable/26511106

The landscape of cancer cell line metabolism

Authors: Li, Haoxin, Ning, Shaoyang, Ghandi, Mahmoud, Kryukov, Gregory, Gopal, Shuba, Deik, Amy, Souza, Amanda, Pierce, Kerry, Keskula, Paula, Hernandez, Desiree, Ann, Julie, Shkoza, Dojna, Apfel, Verena, Zou, Yilong, Vazquez, Francisca, Barretina, Jordi, Pagliarini, Raymond, Galli, Giorgio, Root, David, Hahn, William, Tsherniak, Aviad, Giannakis, Marios, Schreiber, Stuart, Clish, Clary, Garraway, Levi, Sellers, William

Source: Nature medicine. 25(5):850-860

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138191782.0x000001&indx=1&recIds=ETOCvdc_100138191782.0x000001

Gut microbiome structure and metabolic activity in inflammatory bowel disease

Authors: Franzosa, Eric, Sirota-Madi, Alexandra, Avila-Pacheco, Julian, Fornelos, Nadine, Haiser, Henry, Reinker, Stefan, Vatanen, Tommi, Hall, A., Mallick, Himel, McIver, Lauren, Sauk, Jenny, Wilson, Robin, Stevens, Betsy, Scott, Justin, Pierce, Kerry, Deik, Amy, Bullock, Kevin, Imhann, Floris, Porter, Jeffrey, Zhernakova, Alexandra, Fu, Jingyuan, Weersma, Rinse, Wijmenga, Cisca, Clish, Clary, Vlamakis, Hera, Huttenhower, Curtis, Xavier, Ramnik

Source: Nature microbiology. 4(2):293-305

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130625507.0x000001&indx=1&recIds=ETOCvdc_100130625507.0x000001

Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies

Authors: Razquin, Cristina, Ruiz-Canela, Miguel, Clish, Clary, Li, Jun, Toledo, Estefania, Dennis, Courtney, Liang, Liming, Salas-Huetos, Albert, Pierce, Kerry, Guasch-Ferré, Marta, Corella, Dolores, Ros, Emilio, Estruch, Ramon, Gómez-Gracia, Enrique, Fitó, Montse, Lapetra, Jose, Romaguera, Dora, Alonso-Gómez, Angel, Serra-Majem, Lluis, Salas-Salvadó, Jordi, Hu, Frank, Martínez-González, Miguel

Source: Cardiovascular diabetology. 18(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190688868.0x000001&indx=1&recIds=ETOCvdc_100190688868.0x000001

Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults

Authors: Chou, Chih‐Hung, Mohanty, Subhasis, Kang, Heather A., Kong, Lingjia, Avila‐Pacheco, Julian, Joshi, Samit R., Ueda, Ikuyo, Devine, Lesley, Raddassi, Khadir, Pierce, Kerry, Jeanfavre, Sarah, Bullock, Kevin, Meng, Hailong, Clish, Clary, Santori, Fabio R., Shaw, Albert C., Xavier, Ramnik J.

Source: Aging cell. 21(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167118897.0x000001&indx=1&recIds=ETOCvdc_100167118897.0x000001

Involvement of a gut–retina axis in protection against dietary glycemia-induced age-related macular degeneration

Authors: Rowan, Sheldon, Jiang, Shuhong, Korem, Tal, Szymanski, Jedrzej, Chang, Min-Lee, Szelog, Jason, Cassalman, Christa, Dasuri, Kalavathi, McGuire, Christina, Nagai, Ryoji, Du, Xue-Liang, Brownlee, Michael, Rabbani, Naila, Thornalley, Paul J., Baleja, James D., Deik, Amy A., Pierce, Kerry A., Scott, Justin M., Clish, Clary B., Smith, Donald E., Weinberger, Adina, Avnit-Sagi, Tali, Lotan-Pompan, Maya, Segal, Eran, Taylor, Allen

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 May . 114(22), E4472-E4481.

Access URL: https://www.jstor.org/stable/26483405

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

Authors: Ng, Maggie C.Y., Shriner, Daniel, Chen, Brian H., Li, Jiang, Chen, Wei-Min, Guo, Xiuqing, Liu, Jiankang, Bielinski, Suzette J., Yanek, Lisa R., Nalls, Michael A., Comeau, Mary E., Rasmussen-Torvik, Laura J., Jensen, Richard A., Evans, Daniel S., Sun, Yan V., An, Ping, Patel, Sanjay R., Lu, Yingchang, Long, Jirong, Armstrong, Loren L., Wagenknecht, Lynne, Yang, Lingyao, Snively, Beverly M., Palmer, Nicholette D., Mudgal, Poorva, Langefeld, Carl D., Keene, Keith L., Freedman, Barry I., Mychaleckyj, Josyf C., Nayak, Uma, Raffel, Leslie J., Goodarzi, Mark O., Chen, Y-D Ida, Taylor, Herman A., Jr., Correa, Adolfo, Sims, Mario, Couper, David, Pankow, James S., Boerwinkle, Eric, Adeyemo, Adebowale, Doumatey, Ayo, Chen, Guanjie, Mathias, Rasika A., Vaidya, Dhananjay, Singleton, Andrew B., Zonderman, Alan B., Igo, Robert P., Jr., Sedor, John R., Kabagambe, Edmond K., Siscovick, David S., McKnight, Barbara, Rice, Kenneth, Liu, Yongmei, Hsueh, Wen-Chi, Zhao, Wei, Bielak, Lawrence F., Kraja, Aldi, Province, Michael A., Bottinger, Erwin P., Gottesman, Omri, Cai, Qiuyin, Zheng, Wei, Blot, William J., Lowe, William L., Pacheco, Jennifer A., Crawford, Dana C., Grundberg, Elin, Rich, Stephen S., Hayes, M. Geoffrey, Shu, Xiao-Ou, Loos, Ruth J.F., Borecki, Ingrid B., Peyser, Patricia A., Cummings, Steven R., Psaty, Bruce M., Fornage, Myriam, Iyengar, Sudha K., Evans, Michele K., Becker, Diane M., Kao, W.H. Linda, Wilson, James G., Rotter, Jerome I., Sale, Michèle M., Liu, Simin, Rotimi, Charles N., Bowden, Donald W., Mercader, Josep M., Huerta-Chagoya, Alicia, García-Ortiz, Humberto, Moreno-Macías, Hortensia, Manning, Alisa, Caulkins, Lizz, Burtt, Noël P., Flannick, Jason, Patterson, Nick, Aguilar-Salinas, Carlos A., Tusié-Luna, Teresa, Altshuler, David, Florez, Jose C., Martínez-Hernández, Angélica, Centeno-Cruz, Federico, Barajas-Olmos, Francisco Martin, Zerrweck, Carlos, Contreras-Cubas, Cecilia, Mendoza-Caamal, Elvia, Revilla-Monsalve, Cristina, Islas-Andrade, Sergio, Córdova, Emilio, Soberón, Xavier, Orozco, Lorena, González-Villalpando, Clicerio, González-Villalpando, María Elena, Haiman, Christopher A., Wilkens, Lynne, Le Marchand, Loic, Monroe, Kristine, Kolonel, Laurence, Arellano-Campos, Olimpia, Ordóñez-Sánchez, Maria L., Rodríguez-Torres, Maribel, Segura-Kato, Yayoi, Rodríguez-Guillén, Rosario, Cruz-Bautista, Ivette, Muñoz-Hernandez, Linda Liliana, Sáenz, Tamara, Gómez, Donají, Alvirde, Ulices, Almeda-Valdés, Paloma, Cortes, Maria L., Rusu, Victor, Hoch, Eitan, Tenen, Danielle E., Gymrek, Melissa, Hartigan, Christina R., DeRan, Michael, von Grotthuss, Marcin, Fontanillas, Pierre, Spooner, Alexandra, Guzman, Gaelen, Deik, Amy A., Pierce, Kerry A., Dennis, Courtney, Clish, Clary B., Carr, Steven A., Wagner, Bridget K., Schenone, Monica, Altshuler, David M., Schreiber, Stuart L., Jacobs, Suzanne B.R., Lander, Eric S.

Source: In Cell 29 June 2017 170(1):199-212

Gut microbiome structure and metabolic activity in inflammatory bowel disease

Authors: Franzosa, Eric A., Sirota-Madi, Alexandra, Avila-Pacheco, Julian, Fornelos, Nadine, Haiser, Henry J., Reinker, Stefan, Vatanen, Tommi, Hall, A. Brantley, Mallick, Himel, McIver, Lauren J., Sauk, Jenny S., Wilson, Robin G., Stevens, Betsy W., Scott, Justin M., Pierce, Kerry, Deik, Amy A., Bullock, Kevin, Imhann, Floris, Porter, Jeffrey A., Zhernakova, Alexandra, Fu, Jingyuan, Weersma, Rinse K., Wijmenga, Cisca, Clish, Clary B., Vlamakis, Hera, Huttenhower, Curtis, Xavier, Ramnik J.

Source: Nature microbiology. 4(2):293-305

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130017729.0x000001&indx=1&recIds=ETOCvdc_100130017729.0x000001