Plasma fractalkine contributes to systemic myeloid diversity and PD‐L1/PD‐1 blockade in lung cancer

Authors: Bocanegra, Ana, Fernández‐Hinojal, Gonzalo, Ajona, Daniel, Blanco, Ester, Zuazo, Miren, Garnica, Maider, Chocarro, Luisa, Alfaro‐Arnedo, Elvira, Piñeiro‐Hermida, Sergio, Morente, Pilar, Fernández, Leticia, Remirez, Ana, Echaide, Miriam, Martinez‐Aguillo, Maite, Morilla, Idoia, Tavira, Beatriz, Roncero, Alejandra, Gotera, Carolina, Ventura, Alfonso, Recalde, Nerea, Pichel, José G, Lasarte, Juan José, Montuenga, Luis, Vera, Ruth, Pio, Ruben, Escors, David, Kochan, Grazyna

Source: EMBO reports. 24(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196426764.0x000001&indx=1&recIds=ETOCvdc_100196426764.0x000001

Prominent release of lipoxygenase generated mediators in a murine house dust mite-induced asthma model

Authors: Kolmert, Johan, Piñeiro-Hermida, Sergio, Hamberg, Mats, Gregory, Joshua A., López, Icíar P., Fauland, Alexander, Wheelock, Craig E., Dahlén, Sven-Erik, Pichel, José G., Adner, Mikael

Source: In Prostaglandins and Other Lipid Mediators July 2018 137:20-29

Design and Synthesis of Metronidazole‐Based Photoswitches With Potential Biological Applications

Authors: Martínez‐López, David, García‐Iriepa, Cristina, Piñeiro‐Hermida, Sergio, López, Icíar P., Fernández‐Martínez, Diana, Alfaro‐Arnedo, Elvira, Pichel, José G., Campos, Pedro J., Sampedro, Diego

Source: ChemPhotoChem. 3(6):425-430

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084019428.0x000001&indx=1&recIds=ETOCvdc_100084019428.0x000001

Luminescent Cycloplatinated Complexes with Biologically Relevant Phosphine Ligands: Optical and Cytotoxic Properties

Authors: Millán, Gonzalo, Giménez, Nora, Lara, Rebeca, Berenguer, Jesús R., Moreno, M. Teresa, Lalinde, Elena, Alfaro-Arnedo, Elvira, López, Icíar P., Piñeiro-Hermida, Sergio, Pichel, José G.

Source: Inorganic chemistry. 58(2):1657-1673

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632817549&indx=1&recIds=ETOCRN632817549

Short and dysfunctional telomeres protect from allergen‐induced airway inflammation

Authors: Piñeiro‐Hermida, Sergio, Martínez, Paula, Blasco, Maria A.

Source: Aging cell. 20(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120809999.0x000001&indx=1&recIds=ETOCvdc_100120809999.0x000001

Leading Edge: Intratumor Delivery of Monoclonal Antibodies for the Treatment of Solid Tumors.

Authors: Blanco, Ester, Chocarro, Luisa, Fernández-Rubio, Leticia, Bocanegra, Ana, Arasanz, Hugo, Echaide, Miriam, Garnica, Maider, Piñeiro-Hermida, Sergio, Kochan, Grazyna, Escors, David

Source: International Journal of Molecular Sciences; Feb2023, Vol. 24 Issue 3, p2676, 21p

Subject Terms: MONOCLONAL antibodies, TUMOR treatment, IMMUNE checkpoint proteins, GENE therapy, TREATMENT effectiveness, NANOMEDICINE

Telomerase deficiency and dysfunctional telomeres in the lung tumor microenvironment impair tumor progression in NSCLC mouse models and patient-derived xenografts

Authors: Piñeiro-Hermida, Sergio, Bosso, Giuseppe, Sánchez-Vázquez, Raúl, Martínez, Paula, Blasco, Maria A.

Source: Cell Death and Differentiation; June 2023, Vol. 30 Issue: 6 p1585-1600, 16p

Cutting-Edge CAR Engineering: Beyond T Cells.

Authors: Chocarro, Luisa, Blanco, Ester, Fernández-Rubio, Leticia, Arasanz, Hugo, Bocanegra, Ana, Echaide, Miriam, Garnica, Maider, Ramos, Pablo, Piñeiro-Hermida, Sergio, Vera, Ruth, Kochan, Grazyna, Escors, David

Source: Biomedicines; Dec2022, Vol. 10 Issue 12, p3035, 17p

Subject Terms: T cells, CHIMERIC antigen receptors, TUMOR microenvironment, MYELOID cells, CELLULAR therapy

Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma.

Authors: Piñeiro-Hermida, Sergio¹, Alfaro-Arnedo, Elvira¹, Gregory, Joshua A.², Torrens, Raquel¹, Ruíz-Martínez, Carlos³, Adner, Mikael², López, Icíar P.¹, Pichel, José G.¹ jgpichel@riojasalud.es

Source: PLoS ONE. 12/22/2017, Vol. 12 Issue 12, p1-20. 20p.

Subject Terms: *ASTHMA treatment, *BRONCHIAL spasm, *INSULIN-like growth factor receptors, *HOUSE dust mites, *LABORATORY mice

IGF1R is a mediator of sex-specific metabolism in mice: Effects of age and high-fat diet.

Authors: Pérez-Matute, Patricia, López, Icíar P., Íñiguez, María, Recio-Fernández, Emma, Torrens, Raquel, Piñeiro-Hermida, Sergio, Alfaro-Arnedo, Elvira, Luong Chau, Walz, Christina, Hoeflich, Andreas, Oteo, José A., Piche, José G.

Source: Frontiers in Endocrinology; 10/25/2022, Vol. 13, p1-16, 16p

Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development.

Authors: Piñeiro-Hermida, Sergio, Martínez, Paula, Bosso, Giuseppe, Flores, Juana María, Saraswati, Sarita, Connor, Jane, Lemaire, Raphael, Blasco, Maria A.

Source: Nature Communications; 10/6/2022, Vol. 13 Issue 1, p1-18, 18p

Subject Terms: LUNGS, PULMONARY fibrosis, TELOMERES, FIBROBLASTS, CELL cycle, MYOFIBROBLASTS, PNEUMONIA

Immune Profiling Uncovers Memory T-Cell Responses with a Th17 Signature in Cancer Patients with Previous SARS-CoV-2 Infection Followed by mRNA Vaccination.

Authors: Echaide, Miriam, Labiano, Ibone, Delgado, Marina, Fernández de Lascoiti, Angela, Ochoa, Patricia, Garnica, Maider, Ramos, Pablo, Chocarro, Luisa, Fernández, Leticia, Arasanz, Hugo, Bocanegra, Ana, Blanco, Ester, Piñeiro-Hermida, Sergio, Morente, Pilar, Vera, Ruth, Alsina, Maria, Escors, David, Kochan, Grazyna

Source: Cancers; Sep2022, Vol. 14 Issue 18, pN.PAG-N.PAG, 17p

Subject Terms: COVID-19, IMMUNIZATION, CANCER patients, ANTIBODY formation, COMPARATIVE studies, MESSENGER RNA, IMMUNOPHENOTYPING, T cells, IMMUNOLOGIC memory, LONGITUDINAL method

How Can We Improve Vaccination Response in Old People? Part I: Targeting Immunosenescence of Innate Immunity Cells.

Authors: Aiello, Anna, Ligotti, Mattia Emanuela, Garnica, Maider, Accardi, Giulia, Calabrò, Anna, Pojero, Fanny, Arasanz, Hugo, Bocanegra, Ana, Blanco, Ester, Chocarro, Luisa, Echaide, Miriam, Fernandez-Rubio, Leticia, Ramos, Pablo, Piñeiro-Hermida, Sergio, Kochan, Grazyna, Zareian, Nahid, Farzaneh, Farzin, Escors, David, Caruso, Calogero, Candore, Giuseppina

Source: International Journal of Molecular Sciences; Sep2022, Vol. 23 Issue 17, p9880, 18p

Subject Terms: IMMUNOSENESCENCE, NATURAL immunity, OLDER people, KILLER cells, VACCINATION, VACCINE effectiveness, MONOCYTES

Circulating Low Density Neutrophils Are Associated with Resistance to First Line Anti-PD1/PDL1 Immunotherapy in Non-Small Cell Lung Cancer.

Authors: Arasanz, Hugo, Bocanegra, Ana Isabel, Morilla, Idoia, Fernández-Irigoyen, Joaquín, Martínez-Aguillo, Maite, Teijeira, Lucía, Garnica, Maider, Blanco, Ester, Chocarro, Luisa, Ausin, Karina, Zuazo, Miren, Fernández-Hinojal, Gonzalo, Echaide, Miriam, Fernández-Rubio, Leticia, Piñeiro-Hermida, Sergio, Ramos, Pablo, Mezquita, Laura, Escors, David, Vera, Ruth, Kochan, Grazyna

Source: Cancers; Aug2022, Vol. 14 Issue 16, p3846, 14p

Subject Terms: LUNG cancer treatment, NEUTROPHILS, IMMUNOTHERAPY

Cutting-Edge: Preclinical and Clinical Development of the First Approved Lag-3 Inhibitor.

Authors: Chocarro, Luisa, Bocanegra, Ana, Blanco, Ester, Fernández-Rubio, Leticia, Arasanz, Hugo, Echaide, Miriam, Garnica, Maider, Ramos, Pablo, Piñeiro-Hermida, Sergio, Vera, Ruth, Escors, David, Kochan, Grazyna

Source: Cells (2073-4409); Aug2022, Vol. 11 Issue 15, p2351-2351, 24p

Subject Terms: IMMUNE checkpoint proteins, IMMUNE checkpoint inhibitors, BISPECIFIC antibodies, MEDICAL practice, PROGRAMMED cell death 1 receptors, ANTINEOPLASTIC agents, PROGRESSION-free survival

Company/Entity: UNITED States. Food & Drug Administration

Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.

Authors: López, Icíar P.¹, Piñeiro-Hermida, Sergio¹, Pais, Rosete S.¹, Torrens, Raquel¹, Hoeflich, Andreas², Pichel, José G.¹ jgpichel@riojasalud.es

Source: PLoS ONE. 11/18/2016, Vol. 11 Issue 11, p1-32. 32p.

Subject Terms: *SOMATOMEDIN, *EPITHELIAL cells, *LUNG cancer, *PULMONARY fibrosis, *GENE expression, *LABORATORY mice

CAR-T Cells for the Treatment of Lung Cancer.

Authors: Chocarro, Luisa, Arasanz, Hugo, Fernández-Rubio, Leticia, Blanco, Ester, Echaide, Miriam, Bocanegra, Ana, Teijeira, Lucía, Garnica, Maider, Morilla, Idoia, Martínez-Aguillo, Maite, Piñeiro-Hermida, Sergio, Ramos, Pablo, Lasarte, Juan José, Vera, Ruth, Kochan, Grazyna, Escors, David

Source: Life (2075-1729); Apr2022, Vol. 12 Issue 4, pN.PAG-N.PAG, 15p

Subject Terms: LUNG cancer, CANCER treatment, CHIMERIC antigen receptors, CANCER cells, T cells, CELLULAR therapy, HEMATOLOGIC malignancies

Early differential responses elicited by BRAF^V600E in adult mouse models.

Authors: Bosso, Giuseppe, Lanuza-Gracia, Pablo, Piñeiro-Hermida, Sergio, Yilmaz, Merve, Serrano, Rosa, Blasco, Maria A.

Source: Cell Death & Disease; Feb2022, Vol. 13 Issue 2, p1-15, 15p

Telomerase treatment prevents lung profibrotic pathologies associated with physiological aging

Authors: Piñeiro-Hermida, Sergio, Autilio, Chiara, Martínez, Paula, Bosch, Fátima, Pérez-Gil, Jesús, Blasco, Maria A.

Source: Journal of cell biology. 219(10):e202002120-e202002120

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624825103&indx=1&recIds=ETOCRN624825103

IGF1R acts as a cancer-promoting factor in the tumor microenvironment facilitating lung metastasis implantation and progression

Authors: Alfaro-Arnedo, Elvira, López, Icíar P., Piñeiro-Hermida, Sergio, Canalejo, Marta, Gotera, Carolina, Sola, Jesús Javier, Roncero, Alejandra, Peces-Barba, Germán, Ruíz-Martínez, Carlos, Pichel, José G.

Source: Oncogene; 20220101, Issue: Preprints p1-15, 15p