Safety and immunogenicity of a modified mRNA-lipid nanoparticle vaccine candidate against COVID-19: Results from a phase 1, dose-escalation study

Authors: Brandon J. Essink, Craig Shapiro, Marie Grace Dawn Isidro, Paul Bradley, Antoinette Pragalos, Mark Bloch, Joel Santiaguel, Melchor Victor Frias, Spiros Miyakis, Margarida Alves de Mesquita, Stefano Berrè, Charlotte Servais, Natasha Waugh, Claudia Hoffmann, Emna Baba, Oliver Schönborn-Kellenberger, Olaf-Oliver Wolz, Sven D. Koch, Tapiwa Ganyani, Philippe Boutet, Philipp Mann, Stefan O. Mueller, Roshan Ramanathan, Martin Robert Gaudinski, Nicolas Vanhoutte

Source: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Subject Terms: COVID-19, mRNA vaccine, booster, SARS-CoV-2 variants, safety, immunogenicity, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/b801d4c67eeb429f80a7051c7f35eae6

Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19

Authors: Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Nathalie Charland, Aurélien Lorin, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, Robbert Van Der Most, François Roman, Maria Angeles Ceregido, Nathalie Landry, Marc-André D’Aoust, Brian J. Ward

Source: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/5f0bb8c08c0147bdb05f3296700f7ce0

Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities

Authors: Nathalie Charland, Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Annie Séguin, Alexander Makarkov, Gretchen Heizer, Kapil Bhutada, Asif Mahmood, Sonia Trépanier, Karen Hager, Julia Jiang-Wright, Judith Atkins, Pooja Saxena, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, François Roman, Robbert Van Der Most, Maria Angeles Ceregido, Marc Dionne, Guy Tellier, Jean-Sébastien Gauthier, Brandon Essink, Michael Libman, Jason Haffizulla, André Fréchette, Marc-André D’Aoust, Nathalie Landry, Brian J. Ward

Source: npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/b6a4cc5cfcb64d00803666e2639e3ffb

AS03-adjuvanted H7N9 inactivated split virion vaccines induce cross-reactive and protective responses in ferrets

Authors: Daniel Stadlbauer, Leon de Waal, Edith Beaulieu, Shirin Strohmeier, Edwin J. B. Veldhuis Kroeze, Philippe Boutet, Albert D. M. E. Osterhaus, Florian Krammer, Bruce L. Innis, Raffael Nachbagauer, Koert J. Stittelaar, Corey P. Mallett

Source: npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/1f961e1904734a6b881c4f9a5ecc6653

Influenza A(H7N9) Pandemic Preparedness: Assessment of the Breadth of Heterologous Antibody Responses to Emerging Viruses from Multiple Pre-Pandemic Vaccines and Population Immunity

Authors: Min Z. Levine, Crystal Holiday, Yaohui Bai, Weimin Zhong, Feng Liu, Stacie Jefferson, F. Liaini Gross, Wen-pin Tzeng, Louis Fries, Gale Smith, Philippe Boutet, Damien Friel, Bruce L. Innis, Corey P. Mallett, C. Todd Davis, David E. Wentworth, Ian A. York, James Stevens, Jacqueline M. Katz, Terrence Tumpey

Source: Vaccines, Vol 10, Iss 11, p 1856 (2022)

Subject Terms: A(H7N9) viruses, influenza vaccine, pandemic preparedness, population immunity, heterologous cross-reactivity, hemagglutination inhibition, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/10/11/1856; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/68771ddb6ca74390957381a38314d5b0

STAT5 is an ambivalent regulator of neutrophil homeostasis.

Authors: Laurence Fiévez, Christophe Desmet, Emmanuelle Henry, Bernard Pajak, Silke Hegenbarth, Virginie Garzé, Françoise Bex, Fabrice Jaspar, Philippe Boutet, Laurent Gillet, Alain Vanderplasschen, Percy A Knolle, Oberdan Leo, Muriel Moser, Pierre Lekeux, Fabrice Bureau

Source: PLoS ONE, Vol 2, Iss 8, p e727 (2007)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC1939728?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8786a0c1c15948e7af31c8dbcd2de5a3