Mechanism of action and impact of thiol homeostasis on efficacy of an enzyme replacement therapy for classical homocystinuria

Authors: Philipp, Thilo Magnus, Bottiglieri, Teodoro, Clapper, Wilmelenne, Liu, Kai, Rodems, Steve, Szabo, Csaba, Majtan, Tomas

Source: In Redox Biology November 2024 77

Selenium-binding protein 1 (SELENBP1) is a copper-dependent thiol oxidase

Authors: Philipp, Thilo Magnus, Gernoth, Leon, Will, Andreas, Schwarz, Maria, Ohse, Verena Alexia, Kipp, Anna Patricia, Steinbrenner, Holger, Klotz, Lars-Oliver

Source: In Redox Biology September 2023 65

SEMO‐1, a novel methanethiol oxidase in Caenorhabditis elegans, is a pro‐aging factor conferring selective stress resistance

Authors: Philipp, Thilo Magnus, Gong, Weiye, Köhnlein, Karl, Ohse, Verena Alexia, Müller, Frederike Iris, Priebs, Josephine, Steinbrenner, Holger, Klotz, Lars‐Oliver

Source: BioFactors. 48(3):699-706

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153623786.0x000001&indx=1&recIds=ETOCvdc_100153623786.0x000001

A coupled enzyme assay for detection of selenium-binding protein 1 (SELENBP1) methanethiol oxidase (MTO) activity in mature enterocytes

Authors: Philipp, Thilo Magnus, Will, Andreas, Richter, Hannes, Winterhalter, Patrick Rainer, Pohnert, Georg, Steinbrenner, Holger, Klotz, Lars-Oliver

Source: In Redox Biology July 2021 43

Methanethiol: A Scent Mark of Dysregulated Sulfur Metabolism in Cancer.

Authors: Philipp, Thilo Magnus, Scheller, Anne Sophie, Krafczyk, Niklas, Klotz, Lars-Oliver, Steinbrenner, Holger

Source: Antioxidants; Sep2023, Vol. 12 Issue 9, p1780, 12p

Subject Terms: SULFUR metabolism, TERRITORIAL marking (Animals), METHANETHIOL, GUT microbiome, VOLATILE organic compounds, SULFUR compounds

SELENBP1 and SEMO-1: copper-dependent H2S -generating enzymes in humans and in the model organism C. elegans

Authors: Steinbrenner, Holger, Philipp, Thilo Magnus, Schwarz, Maria, Ohse, Verena, Kipp, Anna Patricia, Klotz, Lars-Oliver

Source: In Free Radical Biology and Medicine 20 August 2022 189 Supplement 1

Altered Capacity for H 2 S Production during the Spontaneous Differentiation of Caco-2 Cells to Colonocytes Due to Reciprocal Regulation of CBS and SELENBP1.

Authors: Scheller, Anne Sophie, Philipp, Thilo Magnus, Klotz, Lars-Oliver, Steinbrenner, Holger

Source: Antioxidants; Oct2022, Vol. 11 Issue 10, pN.PAG-N.PAG, 14p

Subject Terms: CELL differentiation, BUTYRATES, METHANETHIOL, HYDROGEN sulfide, CYSTATHIONINE, COLORECTAL cancer

Identification of SELENBP1 as a hydrogen sulfide source in intestinal epithelial cells through a novel methanethiol oxidase assay

Authors: Philipp, Thilo Magnus, Will, Andreas, Köhnlein, Karl, Steinbrenner, Holger, Klotz, Lars-Oliver

Source: In Free Radical Biology and Medicine March 2021 165 Supplement 1:17-17