Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

Authors: Javier Ibanez, Rolf Fendel, Freia-Raphaella Lorenz, Patricia Granados-Bayon, Sina Brückner, Meral Esen, Mihály Sulyok, Zita Sulyok, Steffen Borrmann, Petra Bacher, Alexander Scheffold, Stephen L. Hoffman, Peter G. Kremsner, Benjamin Mordmüller

Source: npj Vaccines, Vol 7, Iss 1, Pp 1-11 (2022)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/557ad6c72b20435e92085c01ea4d8799

Proliferative activity of antigen-specific CD154+ T cells against bacterial and fungal respiratory pathogens in cystic fibrosis decreases after initiation of highly effective CFTR modulator therapy

Authors: Patience N. Eschenhagen, Petra Bacher, Claudia Grehn, Jochen G. Mainz, Alexander Scheffold, Carsten Schwarz

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: cystic fibrosis, antigen-specific T cells, Ki-67, Pseudomonas aeruginosa, Aspergillus fumigatus, total IgE, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1180826/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/09cb2c66fa0b4caa98b0e6a7897dbe5a

Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins

Authors: Hesham ElAbd, Petra Bacher, Andreas Tholey, Tobias L. Lenz, Andre Franke

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: HLA-II & autoimmunity, immunogenicitiy, TCR - T cell receptor, mass-spectrometry (MS) based immunopeptidomics, neoantigen, immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1107266/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/56154be4d93845189cf476223e6cf212

Antigen specificity and cross-reactivity drive functionally diverse anti–Aspergillus fumigatus T cell responses in cystic fibrosis

Authors: Carsten Schwarz, Patience Eschenhagen, Henrijette Schmidt, Thordis Hohnstein, Christina Iwert, Claudia Grehn, Jobst Roehmel, Eva Steinke, Mirjam Stahl, Laura Lozza, Ekaterina Tikhonova, Elisa Rosati, Ulrik Stervbo, Nina Babel, Jochen G. Mainz, Hilmar Wisplinghoff, Frank Ebel, Lei-Jie Jia, Matthew G. Blango, Peter Hortschansky, Sascha Brunke, Bernhard Hube, Axel A. Brakhage, Olaf Kniemeyer, Alexander Scheffold, Petra Bacher

Source: The Journal of Clinical Investigation, Vol 133, Iss 5 (2023)

Subject Terms: Immunology, Pulmonology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/952a35bb46204b4d99016140937e7c30

Malassezia restricta promotes alcohol-induced liver injury

Authors: Suling Zeng, Phillipp Hartmann, Minji Park, Yi Duan, Sonja Lang, Cristina Llorente, Yanhan Wang, Noemí Cabré, Derrick E. Fouts, Petra Bacher, Won Hee Jung, Peter Stärkel, Bernd Schnabl

Source: Hepatology Communications, Vol 7, Iss 2, Pp e0029-e0029 (2023)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HC9.0000000000000029; https://doaj.org/toc/2471-254X

Access URL: https://doaj.org/article/eae067cfc72d464bbe56818bec781709

Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data

Authors: Hesham ElAbd, Frauke Degenhardt, Tomas Koudelka, Ann-Kristin Kamps, Andreas Tholey, Petra Bacher, Tobias L. Lenz, Andre Franke, Mareike Wendorff

Source: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-18 (2021)

Subject Terms: HLA, Immunopeptidomics, Antigen processing and presentation, Computational immunology, Interactive data analysis, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/d574fffae21e41428bede1cb6f4dcb3f

Adoptive Cell Transfer of Allogeneic Epstein–Barr Virus-Specific T Lymphocytes for Treatment of Refractory EBV-Associated Posttransplant Smooth Muscle Tumors: A Case Report

Authors: Bjoern-Thore Hansen, Petra Bacher, Britta Eiz-Vesper, Steffen M. Heckl, Wolfram Klapper, Karoline Koch, Britta Maecker-Kolhoff, Claudia D. Baldus, Lars Fransecky

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: posttransplant smooth muscle tumors, PTSMT, smooth muscle tumor, adoptive cell transfer, virus-specific T cells, alloCELL, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.727814/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/97c4af580f24497e83d1ad8348d91f77

Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones

Authors: Anastasia A Minervina, Mikhail V Pogorelyy, Ekaterina A Komech, Vadim K Karnaukhov, Petra Bacher, Elisa Rosati, Andre Franke, Dmitriy M Chudakov, Ilgar Z Mamedov, Yuri B Lebedev, Thierry Mora, Aleksandra M Walczak

Source: eLife, Vol 9 (2020)

Subject Terms: yellow fever, TCR, single-cell, vaccination, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/53704; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/be440afc27fe45aeb9cbe3fd0dd9c7d1

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus

Authors: Vera Voltersen, Matthew G. Blango, Sahra Herrmann, Franziska Schmidt, Thorsten Heinekamp, Maria Strassburger, Thomas Krüger, Petra Bacher, Jasmin Lother, Esther Weiss, Kerstin Hünniger, Hong Liu, Peter Hortschansky, Alexander Scheffold, Jürgen Löffler, Sven Krappmann, Sandor Nietzsche, Oliver Kurzai, Hermann Einsele, Olaf Kniemeyer, Scott G. Filler, Utz Reichard, Axel A. Brakhage

Source: mBio, Vol 9, Iss 5 (2018)

Subject Terms: Aspergillus fumigatus, CcpA, T cells, dendritic cell, epithelial cell, immune response, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/9fe5a0ecbee347959685d1702c23f58a

Candida-Reactive T Cells for the Diagnosis of Invasive Candida Infection—A Prospective Pilot Study

Authors: Felix C. Koehler, Oliver A. Cornely, Hilmar Wisplinghoff, Astrid C. Schauss, Jon Salmanton-Garcia, Helmut Ostermann, Maren Ziegler, Petra Bacher, Alexander Scheffold, Regina Alex, Anne Richter, Philipp Koehler

Source: Frontiers in Microbiology, Vol 9 (2018)

Subject Terms: invasive candidiasis, candidemia, hepatosplenic candidiasis, flow cytometry, fungus-reactive T cells, CD154, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2018.01381/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/129e6ff20e884ba58a0b8ebfe802a62e

CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

Authors: Anna Nowak, Dominik Lock, Petra Bacher, Thordis Hohnstein, Katrin Vogt, Judith Gottfreund, Pascal Giehr, Julia K. Polansky, Birgit Sawitzki, Andrew Kaiser, Jörn Walter, Alexander Scheffold

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: regulatory T cells, chimeric antigen receptor, adoptive regulatory T cell therapy, regulatory T cell stability, regulatory T cell expansion, regulatory T cell signaling, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2018.00199/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e7874dcbe1cb4db2b548ec313aecd489

Fecal Microbiota Transplantation, Commensal Escherichia coli and Lactobacillus johnsonii Strains Differentially Restore Intestinal and Systemic Adaptive Immune Cell Populations Following Broad-spectrum Antibiotic Treatment

Authors: Ira Ekmekciu, Eliane von Klitzing, Christian Neumann, Petra Bacher, Alexander Scheffold, Stefan Bereswill, Markus M. Heimesaat

Source: Frontiers in Microbiology, Vol 8 (2017)

Subject Terms: commensal intestinal microbiota, Escherichia coli, Lactobacillus johnsonii, fecal microbiota transplantation, secondary abiotic (gnotobiotic) mice, intestinal mucosal and peripheral and central immunity, Microbiology, QR1-502

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fmicb.2017.02430/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/9f570a6a5e1641588b16f6ff8469aeec

The Probiotic Compound VSL#3 Modulates Mucosal, Peripheral, and Systemic Immunity Following Murine Broad-Spectrum Antibiotic Treatment

Authors: Ira Ekmekciu, Eliane von Klitzing, Ulrike Fiebiger, Christian Neumann, Petra Bacher, Alexander Scheffold, Stefan Bereswill, Markus M. Heimesaat

Source: Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)

Subject Terms: probiotics, antibiotics, innate and adaptive immunity, microbiota, fecal microbiota transplantation, secondary abiotic (gnotobiotic) mice, Microbiology, QR1-502

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fcimb.2017.00167/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/d0b775873520400eb5f0025740a03867