High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis

Authors: Goedeke, Leigh ^{1, 2, 3, 8}, Strober, Jordan W. ^{1, 8}, Suh, Rebecca ¹, Paolella, Lauren M. ¹, Li, Xiruo ⁴, Rogers, Jillian C. ¹, Petersen, Max C. ^{4, 5}, Nasiri, Ali R. ¹, Casals, Gregori ¹, Kahn, Mario ¹, Cline, Gary W. ¹, Samuel, Varman T. ^{1, 6}, Shulman, Gerald I. ^{1, 4}, Vatner, Daniel F. ^{1, 6, 7, 9, ∗}

Source: In iScience 15 November 2024 27(11)

Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome

Authors: Adamson, Samantha E., Adak, Sangeeta, Petersen, Max C., Higgins, Dustin, Spears, Larry D., Zhang, Rong Mei, Cedeno, Andrea, McKee, Alexis, Kumar, Aswathi, Singh, Sudhir, Hsu, Fong-Fu, McGill, Janet B., Semenkovich, Clay F.

Source: In Journal of Lipid Research March 2024 65(3)

Dysfunctional adipose tissue and skeletal muscle insulin resistance: Cause and effect or two sides of the same coin?

Authors: Petersen, Max C., Mittendorfer, Bettina

Source: Obesity. 31(5):1185-1187

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180451950.0x000001&indx=1&recIds=ETOCvdc_100180451950.0x000001

Glucagon‐like peptide‐1, glucose‐dependent insulinotropic polypeptide, and glucagon receptor poly‐agonists: a new era in obesity pharmacotherapy

Authors: Malik, Is‐haq O., Petersen, Max C., Klein, Samuel

Source: Obesity. 30(9):1718-1721

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158441587.0x000001&indx=1&recIds=ETOCvdc_100158441587.0x000001

Effect of elexacaftor-tezacaftor-ivacaftor on body weight and metabolic parameters in adults with cystic fibrosis

Authors: Petersen, Max C., Begnel, Lauren, Wallendorf, Michael, Litvin, Marina

Source: Journal of cystic fibrosis. 21(2):265-271

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157669549.0x000001&indx=1&recIds=ETOCvdc_100157669549.0x000001

Effect of dapagliflozin on blood and breath ketones during supervised insulin withdrawal in adults with type 1 diabetes: A randomized crossover trial.

Authors: Petersen, Max C.¹ (AUTHOR) max.p@wustl.edu, Jones, Kai E.¹ (AUTHOR), Markov, Alexander M.¹ (AUTHOR), Salam, Maamoun¹ (AUTHOR), Krutilova, Petra¹ (AUTHOR), McKee, Alexis M.¹ (AUTHOR), Bohnert, Kathryn L.¹ (AUTHOR), Adamson, Samantha E.¹ (AUTHOR), McGill, Janet B.¹ (AUTHOR)

Source: Diabetes, Obesity & Metabolism. Mar2025, p1. 8p. 2 Illustrations.

Subject Terms: *TYPE 1 diabetes, *BLOOD sugar, *SODIUM-glucose cotransporter 2 inhibitors, *DAPAGLIFLOZIN, *KETONES

Metabolic control analysis of hepatic glycogen synthesis in vivo

Authors: Nozaki, Yuichi, Petersen, Max C., Zhang, Dongyan, Vatner, Daniel F., Perry, Rachel J., Abulizi, Abudukadier, Haedersdal, Sofie, Zhang, Xian-Man, Butrico, Gina M., Samuel, Varman T., Mason, Graeme F., Cline, Gary W., Petersen, Kitt F., Rothman, Douglas L., Shulman, Gerald I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Apr 01. 117(14), 8166-8176.

Access URL: https://www.jstor.org/stable/26929764

Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes.

Authors: Petersen, Max C.^1,2 (AUTHOR), Yoshino, Mihoko¹ (AUTHOR), Smith, Gordon I.¹ (AUTHOR), Gaspar, Rafael C.³ (AUTHOR), Kahn, Mario³ (AUTHOR), Samovski, Dmitri¹ (AUTHOR), Shulman, Gerald I.³ (AUTHOR), Klein, Samuel¹ (AUTHOR) sklein@wustl.edu

Source: Diabetes. 12/1/2024, Vol. 73 Issue 12, p2055-2064. 10p.

Subject Terms: *INSULIN sensitivity, *WEIGHT loss, *TYPE 2 diabetes, *SUBCELLULAR fractionation, *CERAMIDES

PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling

Authors: Gassaway, Brandon M., Petersen, Max C., Surovtseva, Yulia V., Barber, Karl W., Sheetz, Joshua B., Aerni, Hans R., Merkel, Jane S., Samuel, Varman T., Shulman, Gerald I., Rinehart, Jesse

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Sep . 115(38), E8996-E9005.

Access URL: https://www.jstor.org/stable/26531185

Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes

Authors: Habtemichael, Estifanos N., Li, Don T., Alcázar-Román, Abel, Westergaard, Xavier O., Li, Muyi, Petersen, Max C., Li, Hanbing, DeVries, Stephen G., Li, Eric, Julca-Zevallos, Omar, Wolenski, Joseph S. ^**, Bogan, Jonathan S.

Source: In Journal of Biological Chemistry 6 July 2018 293(27):10466-10486

Considering the Links Between Nonalcoholic Fatty Liver Disease and Insulin Resistance: Revisiting the Role of Protein Kinase C ε

Authors: Samuel, Varman T., Petersen, Max C., Gassaway, Brandon M., Vatner, Daniel F., Rinehart, Jesse, Shulman, Gerald I., Corey, Kathleen E., Malhi, Harmeet

Source: Hepatology. 70(6):2217-2220

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093622993.0x000001&indx=1&recIds=ETOCvdc_100093622993.0x000001

Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance

Authors: Petersen, Max C., Shulman, Gerald I.

Source: In Trends in Pharmacological Sciences July 2017 38(7):649-665

Impaired plasma glucose clearance is a key determinant of fasting hyperglycemia in people with obesity.

Authors: Mittendorfer, Bettina, van Vliet, Stephan, Smith, Gordon I., Petersen, Max C., Patterson, Bruce W., Klein, Samuel

Source: Obesity (19307381); Mar2024, Vol. 32 Issue 3, p540-546, 7p

Subject Terms: BLOOD sugar, HYPERGLYCEMIA, OBESITY, GLUCOSE

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Authors: Camporez, João-Paulo G., Petersen, Max C., Abudukadier, Abulizi, Moreira, Gabriela V., Jurczak, Michael J., Friedman, Glenn, Haqq, Christopher M., Petersen, Kitt Falk, Shulman, Gerald I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Feb . 113(8), 2212-2217.

Access URL: https://www.jstor.org/stable/26467832

ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content

Authors: Camporez, João Paulo G. ^*, Kanda, Shoichi ^*, Petersen, Max C. ^{*, †}, Jornayvaz, François R. ^*, Samuel, Varman T. ^*, Bhanot, Sanjay ^§, Petersen, Kitt Falk ^*, Jurczak, Michael J. ^*, Shulman, Gerald I. ^{*, †, **}

Source: In Journal of Lipid Research March 2015 56(3):526-536

Reply to Constantin-Teodosiu et al. : Mice with genetic PDH activation are not protected from high-fat diet–induced muscle insulin resistance

Authors: Petersen, Max C., Rahimi, Yasmeen, Camporez, Joao-Paulo G., Pesta, Dominik, Perry, Rachel J., Jurczak, Michael J., Cline, Gary W., Shulman, Gerald I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Feb . 112(8), E825-E825.

Access URL: https://www.jstor.org/stable/26461869

Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids

Authors: Vatner, Daniel F., Majumdar, Sachin K., Kumashiro, Naoki, Petersen, Max C., Rahimi, Yasmeen, Gattu, Arijeet K., Bears, Mitchell, Camporez, João-Paulo G., Cline, Gary W., Jurczak, Michael J., Samuel, Varman T., Shulman, Gerald I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Jan . 112(4), 1143-1148.

Access URL: https://www.jstor.org/stable/26454246

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance

Authors: Rahimi, Yasmeen, Camporez, João-Paulo G., Petersen, Max C., Pesta, Dominik, Perry, Rachel J., Jurczak, Michael J., Cline, Gary W., Shulman, Gerald I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2014 Nov . 111(46), 16508-16513.

Access URL: https://www.jstor.org/stable/43190253

Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production

Authors: Gassaway, Brandon M., Cardone, Rebecca L., Padyana, Anil K., Petersen, Max C., Judd, Evan T., Hayes, Sebastian, Tong, Shuilong, Barber, Karl W., Apostolidi, Maria, Abulizi, Abudukadier, Sheetz, Joshua B., Aerni, Hans R., Gross, Stefan, Kung, Charles, Samuel, Varman T., Shulman, Gerald I., Kibbey, Richard G., Rinehart, Jesse

Source: Cell reports. 29(11):3394-3404.e9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116720835.0x000001&indx=1&recIds=ETOCvdc_100116720835.0x000001

COMPLEX PHYSIOLOGY AND CLINICAL IMPLICATIONS OF TIME-RESTRICTED EATING.

Authors: Petersen, Max C.^1,2, Gallop, Molly R.³, Flores Ramos, Stephany⁴, Zarrinpar, Amir^4,5, Broussard, Josiane L.^6,7, Chondronikola, Maria^8,9, Chaix, Amandine³, Klein, Samuel¹ sklein@wustl.edu

Source: Physiological Reviews. Oct2022, Vol. 102 Issue 4, p1991-2034. 45p.

Subject Terms: *PATHOLOGICAL physiology, *INGESTION, *FOOD consumption, *BODY weight, *INTERMITTENT fasting