The mutational spectrum of NRAS gene discovers a novel frameshift mutation (E49R) in Saudi colorectal cancer patients

Authors: Mahmood Rasool, Absarul Haque, Mohammed Alharthi, Abdulrahman Sibiany, Mohammed Saad Alamri, Samer Mohammed Hassan Alqarni, Irfan A. Rather, Adeel G. Chaudhary, Sajjad Karim, Peter Natesan Pushparaj

Source: Cancer Cell International, Vol 25, Iss 1, Pp 1-10 (2025)

Subject Terms: Colorectal cancer, NRAS gene, Novel mutation, Genetic landscape, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/f42b5955a33144e580b804d1b21bdfab

Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia

Authors: Hind A. Alkhatabi, Peter Natesan Pushparaj

Source: Heliyon, Vol 11, Iss 1, Pp e41266- (2025)

Subject Terms: Alzheimer's disease, Dementia, GREIN, ExpressAnalyst, RNA sequencing, Gene set enrichment analysis, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024172970; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/f43cc364ee79417d946eb73b65946187

The discovery and simulation analysis of a novel mutation c.40 G

Authors: Mahmood Rasool, Absarul Haque, Mohammed Alharthi, Abdulrahman Sibiany, Mohammed Saad Alamri, Samer Mohammed Hassan Alqarni, Irfan A. Rather, Adeel Gulzar Chaudhary, Peter Natesan Pushparaj, Sajjad Karim

Source: Journal of King Saud University: Science, Vol 36, Iss 10, Pp 103477- (2024)

Subject Terms: NRAS, V14F, Colorectal cancer, Novel mutation, 3D homology modeling, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1018364724003896; https://doaj.org/toc/1018-3647

Access URL: https://doaj.org/article/06fabca5c0ef4add91354cf17c34f193

Evaluation of serum biomarkers after intra-articular injection of rat bone marrow-derived mesenchymal stem cells in a rat model of knee osteoarthritis

Authors: Abdulwahab Noorwali, Fadwa Aljoud, Amani Alghamdi, Noora Sattami, Taghreed Bashah, Abdulsalam Noorwali, Peter Natesan Pushparaj, Kalamegam Gauthaman

Source: Heliyon, Vol 10, Iss 21, Pp e39940- (2024)

Subject Terms: Osteoarthritis, Biomarkers, Mesenchymal stem cells, Histomorphometry, Ingenuity pathway analysis, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024159713; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/37c709e0c4ff4e2eb2664a37708ff7fa

Deciphering gene expression signatures in liver metastasized colorectal cancer in stage IV colorectal cancer patients

Authors: Mahmood Rasool, Sajjad Karim, Absarul Haque, Mohammed Alharthi, Adeel G Chaudhary, Peter Natesan Pushparaj

Source: Journal of King Saud University: Science, Vol 36, Iss 9, Pp 103415- (2024)

Subject Terms: Colorectal cancer liver metastasis, Gene expression signature, Gene set enrichment analysis, Differentially expressed genes, Biomarkers, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1018364724003276; https://doaj.org/toc/1018-3647

Access URL: https://doaj.org/article/22de55fa872c4767a0178760a12c01b2

Discovery of a novel mutation F184S (c.551T>C) in GATA4 gene causing congenital heart disease in a consanguineous Saudi family

Authors: Mahmood Rasool, Peter Natesan Pushparaj, Absarul Haque, Ayat Mohammed Shorbaji, Loubna Siraj Mira, Sherin Bakhashab, Mohamed Nabil Alama, Muhammad Farooq, Sajjad Karim, Lars Allan Larsen

Source: Heliyon, Vol 10, Iss 17, Pp e37177- (2024)

Subject Terms: GATA4, F184S, Congenital heart disease, Whole exome sequencing, Homology modelling, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024132082; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/457a87b4a9304fe2848619c2131c0d6d

Interleukin-33 mediated regulation of microRNAs in human cord blood-derived mast cells: Implications for infection, immunity, and inflammation.

Authors: Sherin Bakhashab, Ghalya H Banafea, Farid Ahmed, Nadia Bagatian, Ohoud Subhi, Hans-Juergen Schulten, Peter Natesan Pushparaj

Source: PLoS ONE, Vol 19, Iss 11, p e0314446 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ff00169646ad48439f162cbdec21aecd

Acute and chronic impact of interleukin-33 stimulation on chemokines and growth factors in human cord blood-derived mast cells.

Authors: Sherin Bakhashab, Ghalya H Banafea, Farid Ahmed, Reem Alsolami, Hans-Juergen Schulten, Kalamegam Gauthaman, Muhammad Imran Naseer, Peter Natesan Pushparaj

Source: PLoS ONE, Vol 19, Iss 10, p e0311981 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/965af0eb16324161bc45ecfdea62677a

Immunoprofiling of cytokines, chemokines, and growth factors in female patients with systemic lupus erythematosus– a pilot study

Authors: Laila A. Damiati, Iuliana Denetiu, Sami Bahlas, Samar Damiati, Peter Natesan Pushparaj

Source: BMC Immunology, Vol 24, Iss 1, Pp 1-9 (2023)

Subject Terms: Systemic lupus erythematosus, cytokines, Chemokines, Growth factors, Luminex xMAP technology, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2172

Access URL: https://doaj.org/article/4c2fd6644e8941c8aeb0125478f29e02

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms

Authors: Sherin Bakhashab, Ghalya H. Banafea, Farid Ahmed, Haneen Alsehli, Huda F. AlShaibi, Nadia Bagatian, Ohoud Subhi, Kalamegam Gauthaman, Mahmood Rasool, Hans-Juergen Schulten, Peter Natesan Pushparaj

Source: Experimental and Molecular Pathology, Vol 132, Iss , Pp 104867- (2023)

Subject Terms: Mast cells, Innate immunity, Cord blood, CD117, Immunoglobulin E, Next generation knowledge discovery, Pathology, RB1-214

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0014480023000187; https://doaj.org/toc/1096-0945

Access URL: https://doaj.org/article/e9437a41ac7142348ac6e021b249765f

Thymoquinone (TQ) Inhibits Inflammation and Migration of THP-1 Macrophages: Mechanistic Insights into the Prevention of Atherosclerosis Using In-Vitro and In-Silico Analysis

Authors: Etimad Huwait, Nouf Al-Gharawi, Maryam A. Al-Ghamdi, Mamdooh Gari, Alexandre Prola, Peter Natesan Pushparaj, Gauthaman Kalamegam

Source: Current Issues in Molecular Biology, Vol 44, Iss 4, Pp 1740-1753 (2022)

Subject Terms: thymoquinone, atherosclerosis, THP-1 macrophages, IFN-γ, monocytes migration, cholesterol efflux, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/44/4/120; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/0602cf5c50a44e7ab2d68c8a3e11567b

Exploring the translational potential of clusterin as a biomarker of early osteoarthritis

Authors: Ursule Kalvaityte, Csaba Matta, Eiva Bernotiene, Peter Natesan Pushparaj, Ata M. Kiapour, Ali Mobasheri

Source: Journal of Orthopaedic Translation, Vol 32, Iss , Pp 77-84 (2022)

Subject Terms: Osteoarthritis (OA), Rheumatoid arthritis (RA), Translational biomarker, Clusterin (CLU), Inflammation, Apoptosis, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214031X21000760; https://doaj.org/toc/2214-031X

Access URL: https://doaj.org/article/2963aa86b34746b0af137c5aca96bde5

Corrigendum: Human Wharton’s Jelly stem cell (hWJSC) extracts inhibit ovarian cancer cell lines OVCAR3 and SKOV3 in vitro by inducing cell cycle arrest and apoptosis

Authors: Gauthaman Kalamegam, Khalid Hussein Wali Sait, Farid Ahmed, Roaa Kadam, Peter Natesan Pushparaj, Nisreen Anfinan, Mahmood Rasool, Mohammad Sarwar Jamal, Muhammed Abu-Elmagd, Mohammed Al-Qahtani

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: stem cells, cancer stem cells, cell cycle, cell migration, tumor spheres, gene expression, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1171430/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/b166d0fd12ad4941b72a86c668b992eb

The clusterin connectome: Emerging players in chondrocyte biology and putative exploratory biomarkers of osteoarthritis

Authors: Patrik Kovács, Peter Natesan Pushparaj, Roland Takács, Ali Mobasheri, Csaba Matta

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: clusterin, osteoarthritis, ingenuity pathway analysis, STRING, Cytoscape, connectome, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1103097/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/aebe0eeff2c6489e9706d6c0d02a1aa9

Highly Cited Articles in the Field of Male Infertility and Antioxidants: A Scientometric Analysis

Authors: Ashok Agarwal, Manesh Kumar Panner Selvam, Saradha Baskaran, Renata Finelli, Kristian Leisegang, Cătălina Barbăroșie, Peter Natesan Pushparaj, Kathy Amy Robert, Rafael F. Ambar, Concetta Iovine, Damayanthi Durairajanayagam, Ralf Henkel

Source: The World Journal of Men's Health, Vol 39, Iss 4, Pp 760-775 (2021)

Subject Terms: antioxidants, clinical trial, male infertility, publications, research, Medicine, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690

Access URL: https://doaj.org/article/97547c9a79ed429bbe40496d795a6eec

Editorial: Methods and application in integrative and regenerative pharmacology: 2021

Authors: Peter Natesan Pushparaj, Gauthaman Kalamegam, Seeram Ramakrishna

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: integrative and regenerative pharmacology, MiRNA-21, leptin, wound healing, intervertebral disc degeneration, biomaterials, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.1077352/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/7fb96bcb774a4ff7a3f470a9e0dcb9f0

An In-Depth Bibliometric Analysis and Current Perspective on Male infertility Research

Authors: Saradha Baskaran, Ashok Agarwal, Kristian Leisegang, Peter Natesan Pushparaj, Manesh Kumar Panner Selvam, Ralf Henkel

Source: The World Journal of Men's Health, Vol 39, Iss 2, Pp 302-314 (2021)

Subject Terms: bibliometric analysis, diagnosis, infertility, male, prognosis, publications, Medicine, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690

Access URL: https://doaj.org/article/758a40caffb5412296b388bcaab26f77

Alterations of Spermatozoa Proteomic Profile in Men with Hodgkin’s Disease Prior to Cancer Therapy

Authors: Ana D. Martins, Ashok Agarwal, Saradha Baskaran, Peter Natesan Pushparaj, Gulfam Ahmad, Manesh Kumar Panner Selvam

Source: The World Journal of Men's Health, Vol 38, Iss 4, Pp 521-534 (2020)

Subject Terms: hodgkin disease, infertility, mass spectrometry, proteomics, spermatozoa, transferrin, Medicine, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690

Access URL: https://doaj.org/article/e42a51e771a349bbbcd2ff2a1541e410

Whole-Exome Sequencing Identifies Novel SCN1A and CACNB4 Genes Mutations in the Cohort of Saudi Patients With Epilepsy

Authors: Muhammad Imran Naseer, Angham Abdulrhman Abdulkareem, Mahmood Rasool, Hussein Algahtani, Osama Yousef Muthaffar, Peter Natesan Pushparaj

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: Epilepsy, SCN1A, CACNB4, WES, Saudi patients, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.919996/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/e66c4fa4be3a4fad9252fa826794c6c7

Next-Generation Sequencing Reveals Novel Homozygous Missense Variant c.934T > C in POLR1C Gene Causing Leukodystrophy and Hypomyelinating Disease

Authors: Muhammad Imran Naseer, Angham Abdulrahman Abdulkareem, Peter Natesan Pushparaj, Samah Saharti, Osama Y. Muthaffar

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: POLR1C, intellectual developmental disorder, leukodystrophy, hypomyelinating disease, WES, Saudi family, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.862722/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/db3ec61e9bf844f9b1ab3e5227423a5e