HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor

Authors: Paredes, Felipe, Parra, Valentina, Torrealba, Natalia, Navarro-Marquez, Mario, Gatica, Damian, Bravo-Sagua, Roberto, Troncoso, Rodrigo, Pennanen, Christian, Quiroga, Clara, Chiong, Mario, Caesar, Christa, Taylor, W. Robert, Molgó, Jordi, San Martin, Alejandra, Jaimovich, Enrique, Lavandero, Sergio

Source: In Free Radical Biology and Medicine January 2016 90:206-218

FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes

Authors: Oyarzún, Alejandra P., Westermeier, Francisco, Pennanen, Christian, López-Crisosto, Camila, Parra, Valentina, Sotomayor-Flores, Cristian, Sánchez, Gina, Pedrozo, Zully, Troncoso, Rodrigo, Lavandero, Sergio

Source: In Biochemical Pharmacology 1 November 2015 98(1):92-101

Organelle communication: Signaling crossroads between homeostasis and disease

Authors: Bravo-Sagua, Roberto, Torrealba, Natalia, Paredes, Felipe, Morales, Pablo E., Pennanen, Christian, López-Crisosto, Camila, Troncoso, Rodrigo, Criollo, Alfredo, Chiong, Mario, Hill, Joseph A., Simmen, Thomas, Quest, Andrew F., Lavandero, Sergio

Source: In International Journal of Biochemistry and Cell Biology May 2014 50:55-59

Mitochondrial Dynamics: a Potential New Therapeutic Target for Heart Failure

Alternate Title: Dinámica mitocondrial: un potencial nuevo blanco terapéutico para la insuficiencia cardiaca (Spanish; Castilian)

Authors: Kuzmicic, Jovan, del Campo, Andrea, López-Crisosto, Camila, Morales, Pablo E., Pennanen, Christian, Bravo-Sagua, Roberto, Hechenleitner, Jonathan, Zepeda, Ramiro, Castro, Pablo F., Verdejo, Hugo E., Parra, Valentina, Chiong, Mario, Lavandero, Sergio

Source: In Revista Española de Cardiología (English Edition) 2011 64(10):916-923

Dinámica mitocondrial: un potencial nuevo blanco terapéutico para la insuficiencia cardiaca

Alternate Title: Mitochondrial Dynamics: a Potential New Therapeutic Target for Heart Failure (English)

Authors: Kuzmicic, Jovan, del Campo, Andrea, López-Crisosto, Camila, Morales, Pablo E., Pennanen, Christian, Bravo-Sagua, Roberto, Hechenleitner, Jonathan, Zepeda, Ramiro, Castro, Pablo F., Verdejo, Hugo E., Parra, Valentina, Chiong, Mario, Lavandero, Sergio

Source: In Revista Española de Cardiología 2011 64(10):916-923

Drp1 Loss-of-function Reduces Cardiomyocyte Oxygen Dependence Protecting the Heart From Ischemia-reperfusion Injury

Authors: Zepeda, Ramiro, Kuzmicic, Jovan, Parra, Valentina, Troncoso, Rodrigo, Pennanen, Christian, Riquelme, Jaime A., Pedrozo, Zully, Chiong, Mario, Sánchez, Gina, Lavandero, Sergio

Source: Journal of cardiovascular pharmacology. 63(6):477-487

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100031026326.0x000001&indx=1&recIds=ETOCvdc_100031026326.0x000001

(TTA)n Polymorphism in 3-Hydroxy-3-Methylglutaryl-Coenzyme A and Response to Atorvastatin in Coronary Artery Disease Patients.

Authors: Noriega, Viviana^1,2, Pennanen, Christian^1,2, Sánchez, María Pilar², Chiong, Mario^1,2, Llancaqueo, Marcelo³, Lavandero, Sergio^1,2,4 slavander@uchile.cl, Prieto, Juan Carlos^3,4 jprieto@med.uchile.cl

Source: Basic & Clinical Pharmacology & Toxicology. Mar2009, Vol. 104 Issue 3, p211-215. 5p. 2 Charts, 2 Graphs.

Subject Terms: *GENETIC polymorphisms, *LOW density lipoproteins, *GENETICS, *CHOLESTEROL, *STATINS (Cardiovascular agents), *CORONARY disease

Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway

Authors: Sotomayor-Flores, Cristian, Rivera-Mejías, Pablo, Vásquez-Trincado, César, López-Crisosto, Camila, Morales, Pablo E., Pennanen, Christian, Polakovicova, Iva, Aliaga-Tobar, Víctor, García, Lorena, Roa, Juan Carlos, Rothermel, Beverly A., Maracaja-Coutinho, Vinicius, Ho-Xuan, Hung, Meister, Gunter, Chiong, Mario, Ocaranza, María Paz, Corvalán, Alejandro H., Parra, Valentina, Lavandero, Sergio

Source: Cell Death and Differentiation; September 2020, Vol. 27 Issue: 9 p2586-2604, 19p

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Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca²⁺-calcineurin signaling pathway.

Authors: Pennanen, Christian, Parra, Valentina, López-Crisosto, Camila, Morales, Pablo E., Campo, Andrea del, Gutierrez, Tomás, Rivera-Mejías, Pablo, Kuzmicic, Jovan, Chiong, Mario, Zorzano, Antonio, Rothermel, Beverly A., Lavandero, Sergio

Source: Journal of Cell Science; 6/15/2014, Vol. 127 Issue 12, following p2659-2671, 19p

Subject Terms: MITOCHONDRIAL physiology, MITOCHONDRIAL dynamics, HEART cells, CELL size, CALCINEURIN, CELLULAR signal transduction

Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 Signaling Pathway.

Authors: Parra, Valentina, Verdejo, Hugo E., Iglewski, Myriam, del Campo, Andrea, Troncoso, Rodrigo, Jones, Deborah, Yi Zhu, Kuzmicic, Jovan, Pennanen, Christian, Lopez-Crisosto, Camila, Jaña, Fabián, Ferreira, Jorge, Noguera, Eduard, Chiong, Mario, Bernlohr, David A., Klip, Amira, Hill, Joseph A., Rothermel, Beverly A., Abel, Evan Dale, Zorzano, Antonio

Source: Diabetes; Jan2014, Vol. 63 Issue 1, p75-88, 14p, 1 Color Photograph, 4 Graphs

Subject Terms: MITOCHONDRIA, HEART metabolism, HEART cells, INSULIN research, DIABETES