Negative regulation of miR‐1275 by H3K27me3 is critical for glial induction of glioblastoma cells

Authors: Jialuo Mai, Jiayu Gu, Ying Liu, Xincheng Liu, Ke Sai, Zhijie Chen, Wanjun Lu, Xiaozhi Yang, Jingyi Wang, Cui Guo, Shuxin Sun, Fan Xing, Longxiang Sheng, Bingzheng Lu, Zhu Zhu, Hongjiaqi Sun, Dongdong Xue, Yuan Lin, Jing Cai, Yaqian Tan, Chuntao Li, Wei Yin, Lin Cao, Ying Ou‐yang, Pengxin Qiu, Xingwen Su, Guangmei Yan, Jiankai Liang, Wenbo Zhu

Source: Molecular Oncology, Vol 13, Iss 7, Pp 1589-1604 (2019)

Subject Terms: cAMP, differentiation therapy, GBM, H3K27me3, miR‐1275, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/d7ddbd73683b41da8f7ee1aaf43eb0cc

DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage

Authors: Xiao Xiao, Jiankai Liang, Chunlong Huang, Kai Li, Fan Xing, Wenbo Zhu, Ziqing Lin, Wencang Xu, Guangen Wu, Jifu Zhang, Xi Lin, Yaqian Tan, Jing Cai, Jun Hu, Xueqin Chen, Youwei Huang, Zixi Qin, Pengxin Qiu, Xingwen Su, Lijun Chen, Yuan Lin, Haipeng Zhang, Guangmei Yan

Source: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/dbf1917a6c734ba89788a062a0d2b470

Inhibition of the mevalonate pathway enhances cancer cell oncolysis mediated by M1 virus

Authors: Jiankai Liang, Li Guo, Kai Li, Xiao Xiao, Wenbo Zhu, Xiaoke Zheng, Jun Hu, Haipeng Zhang, Jing Cai, Yaya Yu, Yaqian Tan, Chuntao Li, Xincheng Liu, Cheng Hu, Ying Liu, Pengxin Qiu, Xingwen Su, Songmin He, Yuan Lin, Guangmei Yan

Source: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/eedd8026eda94f72a09d4f75de768ad5

The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes

Authors: Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan, Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao, Pengxin Qiu, Xingwen Su, Wei Yin, Jun Hu, Zhongping Chen, Ke Sai, Jing Wang, Furong Chen, Yinsheng Chen, Shida Zhu, Dongbing Liu, Shiyuan Cheng, Zhi Xie, Wenbo Zhu, Guangmei Yan

Source: Cell Reports, Vol 18, Iss 2, Pp 468-481 (2017)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716317429; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/3968fd8bebf440b692cae7ea5b0da112

The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes

Authors: Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan, Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao, Pengxin Qiu, Xingwen Su, Wei Yin, Jun Hu, Zhongping Chen, Ke Sai, Jing Wang, Furong Chen, Yinsheng Chen, Shida Zhu, Dongbing Liu, Shiyuan Cheng, Zhi Xie, Wenbo Zhu, Guangmei Yan

Source: Cell Reports, Vol 23, Iss 9, Pp 2832-2833 (2018)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124718308209; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/40b43ec9dddd49d687e552cf48854352

A catalog for transcripts in the venom gland of the Agkistrodon acutus: Identification of the toxins potentially involved in coagulopathy

Authors: Qinghua, Liu, Xiaowei, Zhang, Wei, Yin, Chenji, Li, Yijun, Huang, Pengxin, Qiu, Xingwen, Su, Songnian, Hu, Guangmei, Yan

Source: In Biochemical and Biophysical Research Communications 2006 341(2):522-531

Purification and biochemical characterization of F II a, a fibrinolytic enzyme from Agkistrodon acutus venom

Authors: Xiuxia, Liang ^*, Jiashu, Chen, Yingna, Zhou, Pengxin, Qiu, Guangmei, Yan

Source: In Toxicon 2001 39(8):1133-1139

Targeting VCP enhances anticancer activity of oncolytic virus M1 in hepatocellular carcinoma.

Authors: Haipeng Zhang, Kai Li, Yuan Lin, Fan Xing, Xiao Xiao, Jing Cai, Wenbo Zhu, Jiankai Liang, Yaqian Tan, Liwu Fu, Fang Wang, Wei Yin, Bingzheng Lu, Pengxin Qiu, Xingwen Su, Shoufang Gong, Xuetao Bai, Jun Hu, Guangmei Yan

Source: Science Translational Medicine; 8/23/2017, Vol. 9 Issue 404, p1-12, 12p

Subject Terms: CLINICAL trials, LIVER cancer patients, LIVER cancer, PRIMATES, ANTINEOPLASTIC agents

Naturally Existing Oncolytic Virus M1 Is Nonpathogenic for the Nonhuman Primates After Multiple Rounds of Repeated Intravenous Injections.

Authors: Haipeng Zhang, Yuan Lin, Kai Li, Jiankai Liang, Xiao Xiao, Jing Cai, Yaqian Tan, Fan Xing, Jialuo Mai, Yuan Li, Wenli Chen, Longxiang Sheng, Jiayu Gu, Wenbo Zhu, Wei Yin, Pengxin Qiu, Xingwen Su, Bingzheng Lu, Xuyan Tian, Jinhui Liu

Source: Human Gene Therapy; Sep2016, Vol. 27 Issue 9, p700-711, 12p

Effect of glutamate on lysosomal membrane permeabilization in primary cultured cortical neurons.

Authors: MIN YAN, WENBO ZHU, XIAOKE ZHENG, YUAN LI, LIPENG TANG, BINGZHENG LU, WENLI CHEN, PENGXIN QIU, TIANDONG LENG, SUIZHEN LIN, GUANGMEI YAN, WEI YIN

Source: Molecular Medicine Reports; 2016, Vol. 13 Issue 3, p2499-2505, 7p

Subject Terms: LYSOSOMAL storage diseases, PERMEABILITY measurement, GLUTAMIC acid, NERVE cell culture, RECEPTOR antibodies

The Major Cholesterol Metabolite Cholestane-3β,5α,6β- Triol Functions as an Endogenous Neuroprotectant.

Authors: Haiyan Hu, Yuehan Zhou, Tiandong Leng, Ailing Liu, Youqiong Wang, Xiuhua You, Jingkao Chen, Lipeng Tang, Wenli Chen, Pengxin Qiu, Wei Yin, Yijun Huang, Jingxia Zhang, Liwei Wang, Hanfei Sang, Guangmei Yan

Source: Journal of Neuroscience; 8/20/2014, Vol. 34 Issue 34, p11426-11438, 13p

Subject Terms: METHYL aspartate receptors, CEREBRAL ischemia, CHOLESTANES, CENTRAL nervous system, LABORATORY rabbits, NEUROPROTECTIVE agents

Pregnenolone, a cholesterol metabolite, induces glioma cell apoptosis via activating extrinsic and intrinsic apoptotic pathways.

Authors: XIAO XIAO, LIJUN CHEN, YING OUYANG, WENBO ZHU, PENGXIN QIU, XINWEN SU, YUNLING DOU, LIPENG TANG, MIN YAN, HAIPENG ZHANG, XIAOXIAO YANG, DONG XU, GUANGMEI YAN

Source: Oncology Letters; 2014, Vol. 8 Issue 2, p645-650, 6p

Subject Terms: GLIOMA treatment, PREGNENOLONE, CANCER cell physiology, APOPTOSIS, CELL lines, STEROID hormones, THERAPEUTICS

Cholera toxin, a typical protein kinase A activator, induces G1 phase growth arrest in human bladder transitional cell carcinoma cells via inhibiting the c-Raf/MEK/ERK signaling pathway.

Authors: XIAOKE ZHENG, YANQIU OU, MINFENG SHU, YOUQIONG WANG, YUXI ZHOU, XINGWEN SU, WENBO ZHU, WEI YIN, SHIFENG LI, PENGXIN QIU, GUANGMEI YAN, JINGXIA ZHANG, JUN HU, DONG XU

Source: Molecular Medicine Reports; 2014, Vol. 9 Issue 5, p1773-1779, 7p

Subject Terms: CHOLERA toxin, CYCLIC-AMP-dependent protein kinase, TRANSITIONAL cell carcinoma, NEOPLASTIC cell transformation, BLADDER tumors, CELLULAR signal transduction, CELL proliferation

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Crystallization and preliminary X-ray studies of a non-haemorrhagic fibrin(ogen)olytic metalloproteinase from the venom of Agkistrodon acutus.

Authors: Ping Hou, Ming Li, Jiashu Chen, Pengxin Qiu, Xiuxia Liang, Zhiyong Lou, Rao, Zihe, Guangmei Yana

Source: Acta Crystallographica: Section F (Wiley-Blackwell); Apr2005, Vol. 61 Issue 4, p355-358, 4p

Subject Terms: METALLOPROTEINASES, CRYSTALLIZATION, X-rays, FIBRINOLYTIC agents, AGKISTRODON acutus, VENOM

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