Genomic Amplification of TBC1D31 Promotes Hepatocellular Carcinoma Through Reducing the Rab22A‐Mediated Endolysosomal Trafficking and Degradation of EGFR

Authors: Pengbo Cao, Hongxia Chen, Ying Zhang, Qi Zhang, Mengting Shi, Huihui Han, Xiaowen Wang, Liang Jin, Bingqian Guo, Rongjiao Hao, Xi Zhao, Yuanfeng Li, Chengming Gao, Xinyi Liu, Yahui Wang, Aiqing Yang, Chenning Yang, Anfeng Si, Hua Li, Qingfeng Song, Fuchu He, Gangqiao Zhou

Source: Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)

Subject Terms: 8q24.13 amplification, epidermal growth factor receptor (EGFR) trafficking, hepatocellular carcinomas (HCCs), lenvatinib, Rab22A, TBC1D31, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/06200141e7c7443e8bb6aaad1dcc7dc2

Integrative single-cell transcriptomic analyses reveal the cellular ontological and functional heterogeneities of primary and metastatic liver tumors

Authors: Menghui Gui, Shilin Huang, Shizhou Li, Yuying Chen, Furong Cheng, Yulin Liu, Ji-ao Wang, Yuting Wang, Rui Guo, Yiming Lu, Pengbo Cao, Gangqiao Zhou

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-23 (2024)

Subject Terms: Primary liver tumors, Metastatic liver tumors, Single-cell RNA sequencing, Tumor microenvironment, Ontological heterogeneity, Functional heterogeneity, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/2357bc9f32b04898a86c1e3ab7208f5e

The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50

Authors: Chengming Gao, Guangming Zhou, Jie Shi, Peipei Shi, Liang Jin, Yuanfeng Li, Xiaowen Wang, Song Liao, Han Yan, Junjie Wu, Yiming Lu, Yun Zhai, Jinxu Zhang, Haitao Zhang, Hongxing Zhang, Chenning Yang, Pengbo Cao, Shuqun Cheng, Gangqiao Zhou

Source: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)

Subject Terms: Intrahepatic cholangiocarcinoma, RNA editing, KPC1, p105, NF-κB pathway, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/f81ae5ca12934e8d8c4864e53bba5f09

A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma

Authors: Yiming Lu, Aiqing Yang, Cheng Quan, Yingwei Pan, Haoyun Zhang, Yuanfeng Li, Chengming Gao, Hao Lu, Xueting Wang, Pengbo Cao, Hongxia Chen, Shichun Lu, Gangqiao Zhou

Source: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f97323184c2e462c92d5104a0a98d688

Distinct role of histone chaperone Asf1a and Asf1b during fertilization and pre-implantation embryonic development in mice

Authors: Xuemei Wang, Lu Wang, Jie Dou, Tianjiao Yu, Pengbo Cao, Na Fan, Uyunbilig Borjigin, Buhe Nashun

Source: Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-14 (2021)

Subject Terms: Asf1a, Asf1b, Pre-implantation embryos, H3K56ac, Oct4, PCNA, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/9af0b1a1acdb491eb8487bce414b4c22

Hypoxic in vitro culture reduces histone lactylation and impairs pre-implantation embryonic development in mice

Authors: Wanting Yang, Peijun Wang, Pengbo Cao, Shuang Wang, Yuxiao Yang, Huimin Su, Buhe Nashun

Source: Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)

Subject Terms: Histone lactylation, H3K23la, H3K18la, Oxygen, Hypoxia, Pre-implantation embryo, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/b702d2f5d70b4286a662a08f4a46fac1

Genome-wide association study of COVID-19 severity among the Chinese population

Authors: Yuanfeng Li, Yuehua Ke, Xinyi Xia, Yahui Wang, Fanjun Cheng, Xinyi Liu, Xin Jin, Boan Li, Chengyong Xie, Siyang Liu, Weijun Chen, Chenning Yang, Yuguang Niu, Ruizhong Jia, Yong Chen, Xiong Liu, Zhihua Wang, Fang Zheng, Yan Jin, Zhen Li, Ning Yang, Pengbo Cao, Hongxia Chen, Jie Ping, Fuchu He, Changjun Wang, Gangqiao Zhou

Source: Cell Discovery, Vol 7, Iss 1, Pp 1-16 (2021)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2056-5968

Access URL: https://doaj.org/article/13b735a1e1ce47a79b7e5e6f35e163cd

Identification of senescence-associated long non-coding RNAs to predict prognosis and immune microenvironment in patients with hepatocellular carcinoma

Authors: Chengzhi Gao, Guangming Zhou, Min Cheng, Lan Feng, Pengbo Cao, Gangqiao Zhou

Source: Frontiers in Genetics, Vol 13 (2022)

Subject Terms: hepatocellular carcinoma, long noncoding RNA, prognostic signature, immune microenvironment, NRAV, oncogene-induced senescence, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2022.956094/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/419c213bc69f4d0d99b8bc256f699c8d

Emergent Myxobacterial Behaviors Arise from Reversal Suppression Induced by Kin Contacts

Authors: Rajesh Balagam, Pengbo Cao, Govind P. Sah, Zhaoyang Zhang, Kalpana Subedi, Daniel Wall, Oleg A. Igoshin

Source: mSystems, Vol 6, Iss 6 (2021)

Subject Terms: myxobacteria, pattern formation, self-organization, signaling, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/ca43289edc394db7b13d8a6f226fe59c

Direct visualization of a molecular handshake that governs kin recognition and tissue formation in myxobacteria

Authors: Pengbo Cao, Daniel Wall

Source: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f8f31434a85143cea7570956768e2a61

Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome

Authors: Pengbo Cao, Wanting Yang, Peijun Wang, Xihe Li, Buhe Nashun

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: PCOS, DNA methylation, miRNA, transcriptome, granulosa cells, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.664843/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/7d9cb5cff2c74f1f868bd353b0a48281

Characterization of DNA Methylation Patterns and Mining of Epigenetic Markers During Genomic Reprogramming in SCNT Embryos

Authors: Pengbo Cao, Hanshuang Li, Yongchun Zuo, Buhe Nashun

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Subject Terms: DNA methylation, SCNT, WGCNA, epigenetic reprogramming, ZGA, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fcell.2020.570107/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/c62d1f7dd54d4f3788cbb6033ac2a0b1

Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese

Authors: Yuanfeng Li, Lanlan Si, Yun Zhai, Yanling Hu, Zhibin Hu, Jin-Xin Bei, Bobo Xie, Qian Ren, Pengbo Cao, Fei Yang, Qingfeng Song, Zhiyu Bao, Haitao Zhang, Yuqing Han, Zhifu Wang, Xi Chen, Xia Xia, Hongbo Yan, Rui Wang, Ying Zhang, Chengming Gao, Jinfeng Meng, Xinyi Tu, Xinqiang Liang, Ying Cui, Ying Liu, Xiaopan Wu, Zhuo Li, Huifen Wang, Zhaoxia Li, Bo Hu, Minghui He, Zhibo Gao, Xiaobing Xu, Hongzan Ji, Chaohui Yu, Yi Sun, Baocai Xing, Xiaobo Yang, Haiying Zhang, Aihua Tan, Chunlei Wu, Weihua Jia, Shengping Li, Yi-Xin Zeng, Hongbing Shen, Fuchu He, Zengnan Mo, Hongxing Zhang, Gangqiao Zhou

Source: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c96b2ad71ac34492bddea1028cf80543

A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types within the Myxococcales Order

Authors: Pengbo Cao, Xueming Wei, Ram Prasad Awal, Rolf Müller, Daniel Wall

Source: mBio, Vol 10, Iss 1 (2019)

Subject Terms: cell surface, cellular transfer, kin recognition, myxobacteria, polymorphism, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/91e4c5cd49ee415e8cf2b0afcb9467ca

Association of common copy number variations with diseases

Authors: Fei, Yang, Pengbo, Cao, Gangqiao, Zhou

Source: Zhonghua yi xue yi chuan xue za zhi. 33(3):388-391

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN607144975&indx=1&recIds=ETOCRN607144975

Correction: Infectious polymorphic toxins delivered by outer membrane exchange discriminate kin in myxobacteria

Authors: Christopher Vassallo, Pengbo Cao, Austin Conklin, Hayley Finkelstein, Christopher Hayes, Daniel Wall

Source: eLife, Vol 7 (2018)

Subject Terms: Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/37049; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/3c32ccd2d83242b3aa908b0f637316c3

Infectious polymorphic toxins delivered by outer membrane exchange discriminate kin in myxobacteria

Authors: Christopher N Vassallo, Pengbo Cao, Austin Conklin, Hayley Finkelstein, Christopher S Hayes, Daniel Wall

Source: eLife, Vol 6 (2017)

Subject Terms: Myxococcus xanthus, toxins, infectious, myxobacteria, self-recognition, kin discrimination, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/29397; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/38a933023c034dc783a089412767700a

Combined effects of genetic variants of the PTEN, AKT1, MDM2 and p53 genes on the risk of nasopharyngeal carcinoma.

Authors: Xiaoai Zhang, Xi Chen, Yun Zhai, Ying Cui, Pengbo Cao, Hongxing Zhang, Zhihao Wu, Peiyao Li, Lixa Yu, Xia Xia, Fuchu He, Gangqiao Zhou

Source: PLoS ONE, Vol 9, Iss 3, p e92135 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3954877?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f31c8cf8b78546c5b608ff0f8e9d5402

Emergent Myxobacterial Behaviors Arise from Reversal Suppression Induced by Kin Contacts.

Authors: Balagam, Rajesh, Pengbo Cao, Sah, Govind P., Zhang, Zhaoyang, Subedi, Kalpana, Wall, Daniel, Igoshin, Oleg A.

Source: MSystems; Dec2021, Vol. 6 Issue 6, p1-16, 16p

Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.

Authors: Pengbo Cao¹, Aiqing Yang¹, Peiyao Li¹, Xia Xia¹, Yuqing Han¹, Guangming Zhou¹, Rui Wang¹, Fei Yang¹, Yuanfeng Li¹, Ying Zhang¹, Ying Cui², Hongzan Ji³, Lei Lu⁴, Fuchu He⁵ hefc@nic.bmi.ac.cn, Gangqiao Zhou^1,6,7,8 zhougq114@126.com

Source: Science Advances. 8/27/2021, Vol. 7 Issue 35, p1-17. 17p.

Subject Terms: *P53 protein, *P53 antioncogene, *RIBOSOMES, *HEPATOCELLULAR carcinoma, *BIOLOGICAL specimens, *MEDICAL sciences, *GENE expression, *CELL fractionation