Alternative mRNA splicing events and regulators in epidermal differentiation

Authors: Takashima, Shota ^{1, 4}, Sun, Wujianan ^{2, 4}, Otten, Auke B.C. ¹, Cai, Pengfei ², Peng, Shaohong Isaac ¹, Tong, Elton ¹, Bui, Jolina ¹, Mai, McKenzie ¹, Amarbayar, Oyumergen ¹, Cheng, Binbin ¹, Odango, Rowen Jane ¹, Li, Zongkai ², Qu, Kun ², Sun, Bryan K. ^{1, 3, 5, ∗}

Source: In Cell Reports 26 March 2024 43(3)

A peptide inhibitor that rescues polyglutamine-induced synaptic defects and cell death through suppressing RNA and protein toxicities

Authors: Peng, Shaohong Isaac, Leong, Lok I, Sun, Jacquelyne Ka-Li, Chen, Zhefan Stephen, Chow, Hei-Man, Chan, Ho Yin Edwin

Source: In Molecular Therapy - Nucleic Acids 13 September 2022 29:102-115

Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD.

Authors: Chen, Zhefan Stephen, Ou, Mingxi, Taylor, Stephanie, Dafinca, Ruxandra, Peng, Shaohong Isaac, Talbot, Kevin, Chan, Ho Yin Edwin

Source: Nature Communications; 12/21/2023, Vol. 14 Issue 1, p1-19, 19p

Subject Terms: WNT signal transduction, AMYOTROPHIC lateral sclerosis, RNA, CELL polarity, FRONTOTEMPORAL dementia, ZINC-finger proteins