Cathinone metabolism and biliary excretion in an ex-vivo pig liver model: Example of 4-Cl-PVP and eutylone

Authors: Pelletier, Romain ^{a, b, ⁎}, Le Daré, Brendan ^{a, c}, Kerforne, Thomas ^{d, e}, Parvedy, Nicolas Patou ^{a, f}, Lemaitre, Florian ^g, Tron, Camille ^g, Maunand, Kevin ^{a, h}, Corlu, Anne ^a, Morel, Isabelle ^{a, b}, Rayar, Michel ^{a, i}, Gicquel, Thomas ^{a, b}

Source: In Food and Chemical Toxicology February 2025 196

Role of CYP2D6 polymorphisms in tramadol metabolism in a context of co-medications and overweight

Authors: Ferron, Pierre-Jean ^a, Pelletier, Romain ^{a, b}, Massart, Julie ^a, Narjoz, Celine ^c, Tran, Vinh-Hoang-Lan Julie ^c, Loriot, Marie-Anne ^{c, d}, Kernalleguen, Angéline ^a, Zins, Marie ^{d, e}, Kab, Sofiane ^e, Morel, Isabelle ^{a, b}, Clément, Bruno ^a, Gicquel, Thomas ^{a, b}, Le Daré, Brendan ^{a, f, ⁎}

Source: In Food and Chemical Toxicology February 2025 196

Pediatric cannabis intoxication in France and Belgium: A 3-year retrospective study

Authors: Arbouche, Nadia, Gheddar, Laurie, Guyon, Joris, Matheux, Alice, Becam, Jenny, Boland, Lidvine, Bruno, Clément, Descoeur, Juliette, van Den Eede, Nele, Lelong, Jeremy, Bellouard, Marie, Mernissi, Touria, Pelletier, Romain, Thiebot, Pauline, Willeman, Théo, Ameline, Alice, Fabresse, Nicolas

Source: In Toxicologie Analytique et Clinique December 2023 35(4):284-292

Avoiding falsely low creatinine concentrations measured in patients treated with N-acetylcysteine for acetaminophen intoxication using enzymo-amperometric method – An in vitro and in vivo study

Authors: Lefèvre, Charles R., Le Divenah, Felipe, Collet, Nicolas, Pelletier, Romain, Robert, Eric, Ropert, Martine, Pawlowski, Maxime, Gicquel, Thomas, Bendavid, Claude

Source: In Clinica Chimica Acta 1 November 2023 551

Étude nationale du phénomène du chemsex en France : une collaboration interlaboratoire sous l’égide de la Société française de toxicologie analytique (SFTA)

Alternate Title: Chemsex in France: A national study through interlaboratory collaboration under the auspices of the French Society of Analytical Toxicology (SFTA) (English)

Authors: Larabi, Islam Amine, Ghish, Alexandr, Kintz, Pascal, Marillier, Maude, Fabresse, Nicolas, Pelletier, Romain, Knapp, Adeline, Ameline, Alice, Willeman, Théo, Barguil, Yann, Aknouche, Frédéric, Mathieu, Olivier, Chèze, Marjorie, Lelong-Boulouard, Véronique, Matheux, Alice, Le Carpentier, Edouard Charles, Brunet, Bertrand, Gambier, Nicolas, Edel, Yves, Cartiser, Nathalie, Dumestre-Toulet, Véronique, Cohen, Sabine, Lelièvre, Bénédicte, Gaulier, Jean-Michel, Alvarez, Jean-Claude, Pélissier, Anne-Laure

Source: In Toxicologie Analytique et Clinique September 2023 35(3):175-197

Principes et contributions de la mise en réseau moléculaire en toxicologie clinique et médico-légale

Alternate Title: Principles and contributions of molecular networking in clinical and forensic toxicology (English)

Authors: Pelletier, Romain, Le Daré, Brendan, Bourdais, Alexis, Morel, Isabelle, Gicquel, Thomas

Source: In Toxicologie Analytique et Clinique September 2023 35(3):225-234

Multilayer spectrum of intratumoral heterogeneity in basal bladder cancer

Authors: Sirab, Nanor, Drubay, Damien, Maillé, Pascale, Popova, Tatiana, Ngo, Carine, Gentien, David, Moktefi, Anissa, Soyeux‐Porte, Pascale, Pelletier, Romain, Reyes, Cécile, Henry, Emilie, Pouessel, Damien, Vordos, Dimitri, Lebret, Thierry, Reyniès, Aurélien, Paoletti, Xavier, Radvanyi, François, Allory, Yves

Source: Journal of pathology. 256(1):108-118

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139524337.0x000001&indx=1&recIds=ETOCvdc_100139524337.0x000001

Metabolite elucidation of 2‐fluoro‐deschloroketamine (2F‐DCK) using molecular networking across three complementary in vitro and in vivo models

Authors: Gicquel, Thomas, Pelletier, Romain, Richeval, Camille, Gish, Alexandr, Hakim, Florian, Ferron, Pierre‐Jean, Mesli, Vadim, Allorge, Delphine, Morel, Isabelle, Gaulier, Jean‐michel

Source: Drug testing and analysis. 14(1):144-153

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139505192.0x000001&indx=1&recIds=ETOCvdc_100139505192.0x000001

New psychoactive substance cocktail in an intensive care intoxication case elucidated by molecular networking

Authors: Pelletier, Romain, Le Daré, Brendan, Grandin, Loic, Couette, Aurélien, Ferron, Pierre-Jean, Morel, Isabelle, Gicquel, Thomas

Source: Clinical toxicology. 60(1):122-125

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172686190.0x000001&indx=1&recIds=ETOCvdc_100172686190.0x000001

Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study

Authors: Gangneux, Jean-Pierre, Dannaoui, Eric, Fekkar, Arnaud, Luyt, Charles-Edouard, Botterel, Françoise, De Prost, Nicolas, Tadié, Jean-Marc, Reizine, Florian, Houzé, Sandrine, Timsit, Jean-François, Iriart, Xavier, Riu-Poulenc, Béatrice, Sendid, Boualem, Nseir, Saad, Persat, Florence, Wallet, Florent, Le Pape, Patrice, Canet, Emmanuel, Novara, Ana, Manai, Melek, Cateau, Estelle, Thille, Arnaud W, Brun, Sophie, Cohen, Yves, Alanio, Alexandre, Mégarbane, Bruno, Cornet, Muriel, Terzi, Nicolas, Lamhaut, Lionel, Sabourin, Estelle, Desoubeaux, Guillaume, Ehrmann, Stephan, Hennequin, Christophe, Voiriot, Guillaume, Nevez, Gilles, Aubron, Cécile, Letscher-Bru, Valérie, Meziani, Ferhat, Blaize, Marion, Mayaux, Julien, Monsel, Antoine, Boquel, Frédérique, Robert-Gangneux, Florence, Le Tulzo, Yves, Seguin, Philippe, Guegan, Hélène, Autier, Brice, Lesouhaitier, Matthieu, Pelletier, Romain, Belaz, Sorya, Bonnal, Christine, Berry, Antoine, Leroy, Jordan, François, Nadine, Richard, Jean-Christophe, Paulus, Sylvie, Argaud, Laurent, Dupont, Damien, Menotti, Jean, Morio, Florent, Soulié, Marie, Schwebel, Carole, Garnaud, Cécile, Guitard, Juliette, Le Gal, Solène, Quinio, Dorothée, Morcet, Jeff, Laviolle, Bruno, Zahar, Jean-Ralph, Bougnoux, Marie-Elisabeth

Source: Lancet.Respiratory medicine. 10(2):180-190

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154752805.0x000001&indx=1&recIds=ETOCvdc_100154752805.0x000001

Evidence of intoxication by ingestion of toxic fungi: experience at the Rennes University Hospital

Authors: Le Daré, Brendan, Couette, Aurélien, Pelletier, Romain, Morel, Isabelle, Gicquel, Thomas

Source: Annales de biologie clinique. 80(2):141-147

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629426411&indx=1&recIds=ETOCRN629426411

Suitability of high-resolution mass spectrometry in analytical toxicology: Focus on drugs of abuse

Authors: Goncalves, Ruben, Pelletier, Romain, Couette, Aurélien, Gicquel, Thomas, Le Daré, Brendan

Source: In Toxicologie Analytique et Clinique January 2022 34(1) Supplement:29-41

Troponin T cardiac analysis: clinical cases of the limits of its cardiospecificity

Authors: Coirier, Valentin, Pelletier, Romain, Sébillot, Martine, Lefèvre, Charles R., Peltier, Lucas, Collet, Nicolas, Bendavid, Claude, Jégo, Patrick, Moreau, Caroline

Source: Annales de biologie clinique. 79(2):176-180

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626482204&indx=1&recIds=ETOCRN626482204

Reports of the Match 180 seconds from the French-speaking Days of Medical Biology

Authors: Tournoys, Marie-Hélène, Bastide, Mathilda, Delassasseigne, Céline, Despinasse, Quentin, Lacape, Geneviève, Laurelli, Damien, Lefèvre, Charles, Ouaziz, Khadija, Pelletier, Romain, Ruiz, Pablo

Source: Annales de biologie clinique. 79(1):104-111

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626122059&indx=1&recIds=ETOCRN626122059

Arylcyclohexylamine Derivatives: Pharmacokinetic, Pharmacodynamic, Clinical and Forensic Aspects.

Authors: Pelletier, Romain^1,2 (AUTHOR) romain.pelletier@chu-rennes.fr, Le Daré, Brendan^1,3 (AUTHOR), Le Bouëdec, Diane² (AUTHOR), Kernalléguen, Angéline¹ (AUTHOR), Ferron, Pierre-Jean¹ (AUTHOR), Morel, Isabelle^1,2 (AUTHOR), Gicquel, Thomas^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 24, p15574. 19p.

Subject Terms: *KETAMINE, *PHARMACOKINETICS, *METHYL aspartate receptors, *PHENCYCLIDINE, *MIND & body

Geographic Terms: ASIA

A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline.

Authors: Pelletier, Romain^1,2 (AUTHOR), Gicquel, Thomas^1,2 (AUTHOR), Simoes Eugenio, Mélanie^3,4 (AUTHOR), Ferron, Pierre-Jean¹ (AUTHOR), Morel, Isabelle^1,2 (AUTHOR), Delehouzé, Claire⁴ (AUTHOR), Dimanche-Boitrel, Marie-Thérèse^3,4 (AUTHOR), Rousselot, Morgane⁴ (AUTHOR), Le Daré, Brendan^1,5 (AUTHOR) brendan.le.dare@chu-rennes.fr

Source: Pharmaceutics. Dec2022, Vol. 14 Issue 12, p2665. 15p.

Subject Terms: *PROTEIN kinase inhibitors, *RECEPTOR-interacting proteins, *TANDEM mass spectrometry, *PROTEIN receptors, *METABOLIC models

Multiple Ways to Detect IDH2 Mutations in Angioimmunoblastic T-Cell Lymphoma from Immunohistochemistry to Next-Generation Sequencing

Authors: Dupuy, Aurélie, Lemonnier, François, Fataccioli, Virginie, Martin-Garcia, Nadine, Robe, Cyrielle, Pelletier, Romain, Poullot, Elsa, Moktefi, Anissa, Mokhtari, Karima, Rousselet, Marie C., Traverse-Glehen, Alexandra, Delarue, Richard, Tournilhac, Olivier, Delfau-Larue, Marie H., Haioun, Corinne, Ortonne, Nicolas, Copie-Bergman, Christiane, de Leval, Laurence, Pujals, Anaïs, Gaulard, Philippe

Source: In The Journal of Molecular Diagnostics September 2018 20(5):677-685

Severe 25E-NBOH intoxication associated with MDPHP intake: a case report, metabolism study, and literature review.

Authors: Pelletier, Romain^1,2 (AUTHOR) romain.pelletier@chu-rennes.fr, Gicquel, Thomas^1,2 (AUTHOR), Carvelli, Julien³ (AUTHOR), Balaz, Pierre⁴ (AUTHOR), Pelissier-Alicot, Anne-Laure⁵ (AUTHOR), Morel, Isabelle^1,2 (AUTHOR), Bottinelli, Charline⁶ (AUTHOR), Solas, Caroline⁷ (AUTHOR), Le Daré, Brendan^1,8 (AUTHOR), Fabresse, Nicolas^7,9 (AUTHOR)

Source: International Journal of Legal Medicine. May2024, Vol. 138 Issue 3, p815-822. 8p.

Subject Terms: *LIQUID chromatography-mass spectrometry, *SEROTONIN syndrome, *LOSS of consciousness, *METABOLISM, *REFERENCE sources

The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development

Authors: Lemonnier, François, Cairns, Rob A., Inoue, Satoshi, Li, Wanda Y., Dupuy, Aurelie, Broutin, Sophie, Martin, Nadine, Fataccioli, Virginie, Pelletier, Romain, Wakeham, Andrew, Snow, Bryan E., de Leval, Laurence, Pujals, Anais, Haioun, Corinne, Paci, Angelo, Tobin, Erica R., Narayanaswamy, Rohini, Yen, Katherine, Jin, Shengfang, Gaulard, Philippe, Mak, Tak W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Dec . 113(52), 15084-15089.

Access URL: https://www.jstor.org/stable/26473032

In vitro assessment of isopropanol leakage from antiseptic barrier caps into commonly used needleless connectors

Authors: Boissière, Camille, Bacle, Astrid, Pelletier, Romain, Le Bouedec, Diane, Gicquel, Thomas, Lurton, Yves, Le Daré, Brendan

Source: Infection Control & Hospital Epidemiology; May 2024, Vol. 45 Issue: 5 p576-582, 7p