Scalable log-ratio lasso regression for enhanced microbial feature selection with FLORAL

Authors: Fei, Teng, Funnell, Tyler, Waters, Nicholas R., Raj, Sandeep S., Baichoo, Mirae, Sadeghi, Keimya, Dai, Anqi, Miltiadous, Oriana, Shouval, Roni, Lv, Meng, Peled, Jonathan U., Ponce, Doris M., Perales, Miguel-Angel, Gönen, Mithat, van den Brink, Marcel R.M.

Source: In Cell Reports Methods 18 November 2024 4(11)

Phase 2 trial of cyclosporine-A, mycophenolate mofetil, and tocilizumab GVHD prophylaxis in cord blood transplantation

Authors: Politikos, Ioannis ^{1, 2, ∗}, Brown, Samantha ³, Fein, Joshua A. ², Eng, Stephen ¹, Casem, Kristian ¹, Chinapen, Stephanie ¹, Quach, Sean ¹, Scaradavou, Andromachi ^{4, 5}, Cho, Christina ⁶, Dahi, Parastoo ^{1, 2}, Giralt, Sergio A. ^{1, 2}, Gyurkocza, Boglarka ^{1, 2}, Hanash, Alan M. ^{1, 2}, Jakubowski, Ann ^{1, 2}, Papadopoulos, Esperanza B. ^{1, 2}, Perales, Miguel-Angel ^{1, 2}, Ponce, Doris M. ^{1, 2}, Shaffer, Brian C. ^{1, 2}, Tamari, Roni ^{1, 2}, Young, James W. ^{1, 2}, Devlin, Sean ³, Peled, Jonathan U. ^{1, 2}, Barker, Juliet N. ²

Source: In Blood Advances November 2024

Circulating microbial cell–free DNA is increased during neutropenia after hematopoietic stem cell transplantation

Authors: Blair, Lily M., Akhund-Zade, Jamilla, Katsamakis, Zoe A., Smibert, Olivia C., Wolfe, Alex E., Giardina, Paul, Slingerland, John, Bercovici, Sivan, Perales, Miguel-Angel, Taur, Ying, van den Brink, Marcel R. M., Peled, Jonathan U., Markey, Kate A.

Source: In Blood Advances 14 November 2023 7(21):6744-6750

The TaxUMAP atlas: Efficient display of large clinical microbiome data reveals ecological competition in protection against bacteremia

Authors: Schluter, Jonas, Djukovic, Ana, Taylor, Bradford P., Yan, Jinyuan, Duan, Caichen, Hussey, Grant A., Liao, Chen, Sharma, Sneh, Fontana, Emily, Amoretti, Luigi A., Wright, Roberta J., Dai, Anqi, Peled, Jonathan U., Taur, Ying, Perales, Miguel-Angel, Siranosian, Benjamin A., Bhatt, Ami S., van den Brink, Marcel R.M., Pamer, Eric G., Xavier, Joao B.

Source: In Cell Host & Microbe 12 July 2023 31(7):1126-1139

High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients

Authors: Nguyen, Chi L., Markey, Kate A., Miltiadous, Oriana, Dai, Anqi, Waters, Nicholas, Sadeghi, Keimya, Fei, Teng, Shouval, Roni, Taylor, Bradford P., Liao, Chen, Slingerland, John B., Slingerland, Ann E., Clurman, Annelie G., Maloy, Molly A., Bohannon, Lauren, Giardina, Paul A., Brereton, Daniel G., Armijo, Gabriel K., Fontana, Emily, Gradissimo, Ana, Gyurkocza, Boglarka, Sung, Anthony D., Chao, Nelson J., Devlin, Sean M., Taur, Ying, Giralt, Sergio A., Perales, Miguel-Angel, Xavier, Joao B., Pamer, Eric G., Peled, Jonathan U., Gomes, Antonio L.C., van den Brink, Marcel R.M.

Source: In Cell 8 June 2023 186(12):2705-2718

A phase 2 study of interleukin-22 and systemic corticosteroids as initial treatment for acute GVHD of the lower GI tract

Authors: Ponce, Doris M. ^∗, Alousi, Amin M., Nakamura, Ryotaro, Slingerland, John, Calafiore, Marco, Sandhu, Karamjeet S., Barker, Juliet N., Devlin, Sean, Shia, Jinru, Giralt, Sergio, Perales, Miguel-Angel, Moore, Gillian, Fatmi, Samira, Soto, Cristina, Gomes, Antonio, Giardina, Paul, Marcello, LeeAnn, Yan, Xiaoqiang, Tang, Tom, Dreyer, Kevin, Chen, Jianmin, Daley, William L., Peled, Jonathan U., van den Brink, Marcel R. M., Hanash, Alan M.

Source: In Blood 23 March 2023 141(12):1389-1401

Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease

Authors: Burgos da Silva, Marina, Ponce, Doris M., Dai, Anqi, M. Devlin, Sean, Gomes, Antonio L. C., Moore, Gillian, Slingerland, John, Shouval, Roni, Armijo, Gabriel K., DeWolf, Susan, Fei, Teng, Clurman, Annelie, Fontana, Emily, Amoretti, Luigi A., Wright, Roberta J., Andrlova, Hana, Miltiadous, Oriana, Perales, Miguel-Angel, Taur, Ying, Peled, Jonathan U., van den Brink, Marcel R. M.

Source: In Blood 1 December 2022 140(22):2385-2397

A prospective study of dysgeusia and related symptoms in patients with multiple myeloma after autologous hematopoietic cell transplantation

Authors: Scordo, Michael, Shah, Gunjan L., Adintori, Peter A., Knezevic, Andrea, Devlin, Sean M., Buchan, Marissa L., Preston, Elaina V., Lin, Andrew P., Rodriguez, Natasia T., Carino, Caroline A., Nguyen, Linh K., Sitner, Nancy Cruz, Barasch, Andrei, Klang, Mark G., Maloy, Molly A., Mastrogiacomo, Brooke, Carlow, Dean C., Schofield, Ryan C., Slingerland, Ann E., Slingerland, John B., Stein‐Thoeringer, Christoph K., Lahoud, Oscar B., Landau, Heather J., Chung, David J., Brink, Marcel R.M., Peled, Jonathan U., Giralt, Sergio A.

Source: Cancer. 128(21):3850-3859

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185441582.0x000001&indx=1&recIds=ETOCvdc_100185441582.0x000001

Early intestinal microbial features are associated with CD4 T-cell recovery after allogeneic hematopoietic transplant

Authors: Miltiadous, Oriana, Waters, Nicholas R., Andrlová, Hana, Dai, Anqi, Nguyen, Chi L., Burgos da Silva, Marina, Lindner, Sarah, Slingerland, John, Giardina, Paul, Clurman, Annelie, Armijo, Gabriel K., Gomes, Antonio L.C., Lakkaraja, Madhavi, Maslak, Peter, Scordo, Michael, Shouval, Roni, Staffas, Anna, O'Reilly, Richard, Taur, Ying, Prockop, Susan, Boelens, Jaap Jan, Giralt, Sergio, Perales, Miguel-Angel, Devlin, Sean M., Peled, Jonathan U., Markey, Kate A., van den Brink, Marcel R.M.

Source: Blood. 139(18):2758-2769

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183251354.0x000001&indx=1&recIds=ETOCvdc_100183251354.0x000001

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease

Authors: Docampo, Melissa D., da Silva, Marina B., Lazrak, Amina, Nichols, Katherine B., Lieberman, Sophia R., Slingerland, Ann E., Armijo, Gabriel K., Shono, Yusuke, Nguyen, Chi, Monette, Sebastien, Dwomoh, Emmanuel, Lee, Nicole, Geary, Clair D., Perobelli, Suelen M., Smith, Melody, Markey, Kate A., Vardhana, Santosha A., Kousa, Anastasia I., Zamir, Eli, Greenfield, Itamar, Sun, Joseph C., Cross, Justin R., Peled, Jonathan U., Jenq, Robert R., Stein-Thoeringer, Christoph K., van den Brink, Marcel R.M.

Source: Blood. 139(15):2392-2405

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183251551.0x000001&indx=1&recIds=ETOCvdc_100183251551.0x000001

Fecal microbiota diversity disruption and clinical outcomes after auto-HCT: a multicenter observational study

Authors: Khan, Niloufer, Lindner, Sarah, Gomes, Antonio L.C., Devlin, Sean M., Shah, Gunjan L., Sung, Anthony D., Sauter, Craig S., Landau, Heather J., Dahi, Parastoo B., Perales, Miguel-Angel, Chung, David J., Lesokhin, Alexander M., Dai, Anqi, Clurman, Annelie, Slingerland, John B., Slingerland, Ann E., Brereton, Daniel G., Giardina, Paul A., Maloy, Molly, Armijo, Gabriel K., Rondon-Clavo, Carlos, Fontana, Emily, Bohannon, Lauren, Ramalingam, Sendhilnathan, Bush, Amy T., Lew, Meagan V., Messina, Julia A., Littmann, Eric, Taur, Ying, Jenq, Robert R., Chao, Nelson J., Giralt, Sergio, Markey, Kate A., Pamer, Eric G., van den Brink, Marcel R.M. ^*, Peled, Jonathan U. ^{*, *}

Source: In Blood 18 March 2021 137(11):1527-1537

High progression-free survival after intermediate intensity double unit cord blood transplantation in adults

Authors: Barker, Juliet N., Devlin, Sean M., Naputo, Kristine A., Skinner, Kelcey, Maloy, Molly A., Flynn, Lisa, Anagnostou, Theodora, Avecilla, Scott T., Scaradavou, Andromachi, Cho, Christina, Dahi, Parastoo B., Giralt, Sergio A., Gyurkocza, Boglarka, Hanash, Alan M., Hsu, Katharine, Jakubowski, Ann A., Papadopoulos, Esperanza B., Peled, Jonathan U., Perales, Miguel-Angel, Sauter, Craig S., Shah, Gunjan L., Shaffer, Brian C., Tamari, Roni, Young, James W., Roshal, Mikhail, O'Reilly, Richard J., Ponce, Doris M., Politikos, Ioannis

Source: In Blood Advances 8 December 2020 4(23):6064-6076

Profiling the Fungal Microbiome after Fecal Microbiota Transplantation for Graft-versus-Host Disease: Insights from a Phase 1 Interventional Study

Authors: van Lier, Yannouck F., Rolling, Thierry, Armijo, Gabriel K., Zhai, Bing, Haverkate, Nienke J.E., Meijer, Ellen, Nur, Erfan, Blom, Bianca, Peled, Jonathan U., van den Brink, Marcel R.M., Hohl, Tobias M., Hazenberg, Mette D., Markey, Kate A.

Source: Transplantation and Cellular Therapy. 29(1):63.e1-63.e5

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178512069.0x000001&indx=1&recIds=ETOCvdc_100178512069.0x000001

Minimal residual disease negativity in multiple myeloma is associated with intestinal microbiota composition

Authors: Pianko, Matthew J., Devlin, Sean M., Littmann, Eric R., Chansakul, Aisara, Mastey, Donna, Salcedo, Meghan, Fontana, Emily, Ling, Lilan, Tavitian, Elizabet, Slingerland, John B., Slingerland, Ann E., Clurman, Annelie, Gomes, Antonio L.C., Taur, Ying, Pamer, Eric G., Peled, Jonathan U., van den Brink, Marcel R.M., Landgren, Ola, Lesokhin, Alexander M.

Source: In Blood Advances 9 July 2019 3(13):2040-2044

An alpha‐defensin gene single nucleotide polymorphism modulates the gut microbiota and may alter the risk of acute graft‐versus‐host disease

Authors: Rashidi, Armin, Herman, Adam, Gomes, Antonio L. C., Peled, Jonathan U., Jenq, Robert R., Brereton, Daniel G., Staley, Christopher, Blazar, Bruce R., Weisdorf, Daniel J.

Source: British journal of haematology. 189(5):926-930

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120259482.0x000001&indx=1&recIds=ETOCvdc_100120259482.0x000001

Therapeutics Targeting the Gut Microbiome: Rigorous Pipelines for Drug Development

Authors: Markey, Kate A., van den Brink, Marcel R.M., Peled, Jonathan U.

Source: Cell host & microbe. 27(2):169-172

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099448366.0x000001&indx=1&recIds=ETOCvdc_100099448366.0x000001

Update in clinical and mouse microbiota research in allogeneic haematopoietic cell transplantation

Authors: Lindner, Sarah, Peled, Jonathan U.

Source: Current opinion in hematology. 27(6):360-367

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112492669.0x000001&indx=1&recIds=ETOCvdc_100112492669.0x000001

Pilot Trial of Homebound Hematopoietic Cell Transplantation

Authors: Landau, Heather J., Orlando, Evelyn, Rodriguez, Elizabeth S., Applebaum, Allison, Mitchell, Hannah-Rose, Peled, Jonathan U., Khan, Niloufer, Funnell, Tyler, Chung, David, Scordo, Michael, Shah, Gunjan L., LeStrange, Nicole J., Hambright, Katie A., McElrath, Courtney M., Cazeau, Naomi, Devlin, Sean M., Perales, Miguel-Angel, van den Brink, Marcel R.M., Giralt, Sergio A.

Source: In Transplantation and Cellular Therapy December 2022 28(12):832-832

Vitamin D Insufficiency and Clinical Outcomes with Chimeric Antigen Receptor T-Cell Therapy in Large B-cell Lymphoma

Authors: Nath, Karthik, Tomas, Ana Alarcon, Flynn, Jessica, Fein, Joshua A., Alperovich, Anna, Anagnostou, Theodora, Batlevi, Connie Lee, Dahi, Parastoo B., Fingrut, Warren B., Giralt, Sergio A., Lin, Richard J., Palomba, M. Lia, Peled, Jonathan U., Salles, Gilles, Sauter, Craig S., Scordo, Michael, Fraint, Ellen, Feuer, Elise, Shah, Nishi, Slingerland, John B., Devlin, Sean, Shah, Gunjan L., Gupta, Gaurav, Perales, Miguel-Angel, Shouval, Roni

Source: In Transplantation and Cellular Therapy November 2022 28(11):751-751

Impact of gut colonization with butyrate-producing microbiota on respiratory viral infection following allo-HCT

Authors: Haak, Bastiaan W., Littmann, Eric R., Chaubard, Jean-Luc, Pickard, Amanda J., Fontana, Emily, Adhi, Fatima, Gyaltshen, Yangtsho, Ling, Lilan, Morjaria, Sejal M., Peled, Jonathan U., van den Brink, Marcel R., Geyer, Alexander I., Cross, Justin R., Pamer, Eric G., Taur, Ying

Source: In Blood 28 June 2018 131(26):2978-2986