Automated Insulin Delivery for Hypoglycemia Avoidance and Glucose Counterregulation in Long-Standing Type 1 Diabetes with Hypoglycemia Unawareness

Authors: Flatt, Anneliese J., Peleckis, Amy J., Dalton-Bakes, Cornelia, Nguyen, Huong-Lan, Ilany, Sarah, Matus, Austin, Malone, Susan K., Goel, Namni, Jang, Sooyong, Weimer, James, Lee, Insup, Rickels, Michael R.

Source: Diabetes technology & therapeutics. 25(5):302-314

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181325826.0x000001&indx=1&recIds=ETOCvdc_100181325826.0x000001

Validating and Establishing a Diagnostic Threshold for the Hypoglycemia Awareness Questionnaire Impaired Awareness Subscale

Authors: Matus, Austin, Flatt, Anneliese J., Peleckis, Amy J., Dalton-Bakes, Cornelia, Riegel, Barbara, Rickels, Michael R.

Source: In Endocrine Practice October 2023 29(10):762-769

Automated Insulin Delivery in Older Adults with Type 1 Diabetes.

Authors: Kudva, Yogish C., Henderson, Robert J., Kanapka, Lauren G., Weinstock, Ruth S., Rickels, Michael R., Pratley, Richard E., Chaytor, Naomi, Janess, Kamille, Desjardins, Donna, Pattan, Vishwanath, Peleckis, Amy J., Casu, Anna, Rizvi, Shafaq Raza, Bzdick, Suzan, Whitaker, Keri J., Jo Kamimoto, Jorge L., Miller, Kellee, Kollman, Craig, Beck, Roy W.

Source: NEJM Evidence; Jan2025, Vol. 4 Issue 1, p1-21, 21p

Subject Terms: GLYCOSYLATED hemoglobin, STATISTICAL sampling, INSULIN pumps, RANDOMIZED controlled trials, RESEARCH, CONTINUOUS glucose monitoring, AUTOMATION, CONFIDENCE intervals, DIABETES, HYPOGLYCEMIA, OLD age

Effect of Sitagliptin on Islet Function in Pancreatic Insufficient Cystic Fibrosis With Abnormal Glucose Tolerance

Authors: Kelly, Andrea, Sheikh, Saba, Stefanovski, Darko, Peleckis, Amy J, Nyirjesy, Sarah C, Eiel, Jack N, Sidhaye, Aniket, Localio, Russell, Gallop, Robert, De Leon, Diva D, Hadjiliadis, Denis, Rubenstein, Ronald C, Rickels, Michael R

Source: Journal of clinical endocrinology & metabolism. 106(9):2617-2634

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135804011.0x000001&indx=1&recIds=ETOCvdc_100135804011.0x000001

Prolonged Use of an Automated Insulin Delivery System Improves Sleep in Long-Standing Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia.

Authors: Malone, Susan Kohl, Matus, Austin M., Flatt, Anneliese J., Peleckis, Amy J., Grunin, Laura, Yu, Gary, Jang, Sooyong, Weimer, James, Lee, Insup, Rickels, Michael R., Goel, Namni

Source: Journal of Diabetes Science & Technology; Nov2024, Vol. 18 Issue 6, p1416-1423, 8p

α- or β-Adrenergic blockade does not affect transplanted islet cell responses to hypoglycemia in type 1 diabetes.

Authors: Rickels, Michael R., Bellin, Melena D., Stefanovski, Darko, Peleckis, Amy J., Dalton-Bakes, Cornelia, Markmann, Eileen, Nguyen, Huong-Lan, Townsend, Raymond R., Hering, Bernhard J., Naji, Ali

Source: American Journal of Physiology: Endocrinology & Metabolism; Sep2024, Vol. 327 Issue 3, pE290-E301, 12p

Subject Terms: TYPE 1 diabetes, FREE fatty acids, ADRENERGIC receptors, HYPOGLYCEMIA, ISLANDS of Langerhans, INSULIN, TACROLIMUS

Islet Hormone and Incretin Secretion in Cystic Fibrosis after Four Months of Ivacaftor Therapy

Authors: Kelly, Andrea, De Leon, Diva D., Sheikh, Saba, Camburn, Devaney, Kubrak, Christina, Peleckis, Amy J., Stefanovski, Darko, Hadjiliadis, Denis, Rickels, Michael R., Rubenstein, Ronald C.

Source: American journal of respiratory and critical care medicine. 199(3):342-351

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN618972912&indx=1&recIds=ETOCRN618972912

Preservation of β-cell Function in Pancreatic Insufficient Cystic Fibrosis With Highly Effective CFTR Modulator Therapy.

Authors: Flatt, Anneliese J, Sheikh, Saba, Peleckis, Amy J, Alvarado, Paola, Hadjiliadis, Denis, Stefanovski, Darko, Gallop, Robert J, Rubenstein, Ronald C, Kelly, Andrea, Rickels, Michael R

Source: Journal of Clinical Endocrinology & Metabolism; Jan2024, Vol. 109 Issue 1, p151-160, 10p

Subject Terms: CYSTIC fibrosis treatment, CYSTIC fibrosis transmembrane conductance regulator

Characterizing Glycemic Control and Sleep in Adults with Long-Standing Type 1 Diabetes and Hypoglycemia Unawareness Initiating Hybrid Closed Loop Insulin Delivery.

Authors: Malone, Susan Kohl¹ (AUTHOR), Peleckis, Amy J.² (AUTHOR), Grunin, Laura¹ (AUTHOR), Yu, Gary¹ (AUTHOR), Jang, Sooyong³ (AUTHOR), Weimer, James³ (AUTHOR), Lee, Insup³ (AUTHOR), Rickels, Michael R.² (AUTHOR), Goel, Namni⁴ (AUTHOR)

Source: Journal of Diabetes Research. 2/13/2021, p1-8. 8p.

Subject Terms: *TYPE 1 diabetes, *GLYCEMIC control, *HYPOGLYCEMIA, *INSULIN, *SLEEP, *TYPE 2 diabetes

Long-Term Improvement in Glucose Control and Counterregulation by Islet Transplantation for Type 1 Diabetes

Authors: Rickels, Michael R., Peleckis, Amy J., Markmann, Eileen, Dalton-Bakes, Cornelia, Kong, Stephanie M., Teff, Karen L., Naji, Ali

Source: Journal of clinical endocrinology and metabolism. 101(11):4421-4430

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608806591&indx=1&recIds=ETOCRN608806591

Effects of GLP-1 and GIP on Islet Function in Glucose-Intolerant, Pancreatic-Insufficient Cystic Fibrosis.

Authors: Nyirjesy, Sarah C., Peleckis, Amy J., Eiel, Jack N., Gallagher, Kathryn, Doliba, Andriana, Tami, Abigail, Flatt, Anneliese J., De Leon, Diva D., Hadjiliadis, Denis, Sheikh, Saba, Stefanovski, Darko, Gallop, Robert, D'Alessio, David A., Rubenstein, Ronald C., Kelly, Andrea kellya@email.chop.edu, Rickels, Michael R. kellya@email.chop.edu

Source: Diabetes. Oct2022, Vol. 71 Issue 10, p2153-2165. 13p.

Subject Terms: *RESEARCH, *GLUCAGON-like peptide 1, *RESEARCH methodology, *INCRETINS, *BLOOD sugar, *ARGININE, *EVALUATION research, *CYSTIC fibrosis, *INSULIN, *GLUCAGON, *COMPARATIVE studies, *RANDOMIZED controlled trials, *PROINSULIN, *RESEARCH funding, *GLUCOSE

Evaluation of Clinical Metrics for Identifying Defective Physiologic Responses to Hypoglycemia in Long-Standing Type 1 Diabetes.

Authors: Flatt, Anneliese J., Chen, Elizabeth, Peleckis, Amy J., Dalton-Bakes, Cornelia, Nguyen, Huong-Lan, Collins, Heather W., Millar, John S., Gallop, Robert J., Rickels, Michael R.

Source: Diabetes Technology & Therapeutics; Oct2022, Vol. 24 Issue 10, p737-748, 12p

306.1: Clinical Metrics Predict Defective Physiologic Responses to Hypoglycemia in Long-standing Type 1 Diabetes and May Facilitate Early Consideration of Referral for Beta-Cell Replacement Therapy

Authors: Flatt, Anneliese, Chen, Elizabeth, Peleckis, Amy J., Dalton-Bakes, Cornelia, Nguyen, Huong-Lan, Gallop, Robert, Rickels, Michael R.

Source: Transplantation. 105(12S1):S18-S18

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188374887.0x000001&indx=1&recIds=ETOCvdc_100188374887.0x000001

Erratum to: Effect of Sitagliptin on Islet Function in Pancreatic Insufficient Cystic Fibrosis With Abnormal Glucose Tolerance

Authors: Kelly, Andrea, Sheikh, Saba, Stefanovski, Darko, Peleckis, Amy J, Nyirjesy, Sarah C, Eiel, Jack N, Sidhaye, Aniket, Localio, Russell, Gallop, Robert, De Leon, Diva D, Hadjiliadis, Denis, Rubenstein, Ronald C, Rickels, Michael R

Source: Journal of clinical endocrinology & metabolism. 107(4):e1777-e1777

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152521366.0x000001&indx=1&recIds=ETOCvdc_100152521366.0x000001

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β‐Cell secretory defects are present in pancreatic insufficient cystic fibrosis with 1‐hour oral glucose tolerance test glucose ≥155 mg/dL.

Authors: Nyirjesy, Sarah C, Sheikh, Saba, Hadjiliadis, Denis, De Leon, Diva D, Peleckis, Amy J, Eiel, Jack N, Kubrak, Christina, Stefanovski, Darko, Rubenstein, Ronald C, Rickels, Michael R, Kelly, Andrea

Source: Pediatric Diabetes; Nov2018, Vol. 19 Issue 7, p1173-1182, 10p, 3 Charts, 3 Graphs

Subject Terms: CYSTIC fibrosis diagnosis, ARGININE, BLOOD sugar, C-peptide, GLUCOSE tolerance tests, HYPERGLYCEMIA, INGESTION, INSULIN, ISLANDS of Langerhans, PROINSULIN, SECRETION, CROSS-sectional method, GLUCOSE intolerance, GLUCOSE clamp technique

Geographic Terms: PENNSYLVANIA

Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance.

Authors: Sheikh, Saba, Gudipaty, Lalitha, De Leon, Diva D., Hadjiliadis, Denis, Kubrak, Christina, Rosenfeld, Nora K., Nyirjesy, Sarah C., Peleckis, Amy J., Malik, Saloni, Stefanovski, Darko, Cuchel, Marina, Rubenstein, Ronald C., Kelly, Andrea, Rickels, Michael R.

Source: Diabetes; Jan2017, Vol. 66 Issue 1, p134-144, 11p, 4 Charts, 3 Graphs

Subject Terms: HYPERGLYCEMIA, CYSTIC fibrosis, EXOCRINE pancreatic insufficiency, GLUCOSE tolerance tests, PANCREATIC beta cells, INSULIN regulation, GLUCAGON-like peptide 1, PATIENTS, PHYSIOLOGY, DISEASE risk factors