Novel Anti-Viral Properties of the Herbal Extract of Davallia mariesii against Influenza A Virus

Authors: Yu-Li Chen, Pei-Yu Chao, Chung-Fan Hsieh, Pei-Wen Hsieh, Jim-Tong Horng

Source: Viruses, Vol 16, Iss 4, p 523 (2024)

Subject Terms: Gu-Sui-Bu, Davallia mariesii, hemagglutination, influenza A virus, neuraminidase, Microbiology, QR1-502

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Relation: https://www.mdpi.com/1999-4915/16/4/523; https://doaj.org/toc/1999-4915

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Melastoma malabathricum L. Suppresses Neutrophil Extracellular Trap Formation Induced by Synthetic Analog of Viral Double-Stranded RNA Associated with SARS-CoV-2 Infection

Authors: Tse-Hung Huang, Pei-Wen Hsieh, Tsu-Jung Chen, Hui-Ju Tsai, Ju-Chien Cheng, Hsiang-Ruei Liao, Shun-Li Kuo, Ching-Ping Tseng

Source: Pathogens, Vol 12, Iss 2, p 341 (2023)

Subject Terms: double-stranded RNA, neutrophil extracellular trap, platelet aggregation, SARS-CoV-2 infection, traditional Chinese medicine, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/12/2/341; https://doaj.org/toc/2076-0817

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Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors

Authors: Chung-Fan Hsieh, Jia-Rong Jheng, Guan-Hua Lin, Yu-Li Chen, Jin-Yuan Ho, Chien-Jou Liu, Kuei-Yang Hsu, Yuan-Siao Chen, Yoke Fun Chan, Hui-Ming Yu, Pei-Wen Hsieh, Jyh-Haur Chern, Jim-Tong Horng

Source: Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1194-1205 (2020)

Subject Terms: Enterovirus A71, five-fold axis, heparan sulfate, P-selectin glycoprotein ligand-1, receptor, rosmarinic acid, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/b45d4f4b770747599437838685b96c2c

Mechanical Behavior Analysis of Excavation and Retaining Piles in Gravel Formation along Adjacent Railways: A Comparative 3D FEM Study with Monitoring Data

Authors: Yu-Lin Lee, Wen-Kuei Hsu, Pei-Wen Hsieh, Chi-Huang Ma, Ming-Yi Lin, Chi-Min Lee

Source: Applied Sciences, Vol 13, Iss 1, p 397 (2022)

Subject Terms: retaining piles, 3D finite element analysis, monitoring data, gravel formation, adjacent railway, mechanical behavior, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

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Relation: https://www.mdpi.com/2076-3417/13/1/397; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/5211878e0a47466db1610d79a032ef2a

Inverse Analysis for the Convergence-Confinement Method in Tunneling

Authors: Yu-Lin Lee, Wei-Cheng Kao, Chih-Sheng Chen, Chi-Huang Ma, Pei-Wen Hsieh, Chi-Min Lee

Source: Mathematics, Vol 10, Iss 8, p 1223 (2022)

Subject Terms: inverse problems, inverse calculation method, tunnel analysis, convergence-confinement method, support-ground interaction, Newton’s recursive method, Mathematics, QA1-939

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Relation: https://www.mdpi.com/2227-7390/10/8/1223; https://doaj.org/toc/2227-7390

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Verification and Comparison of Direct Calculation Method for the Analysis of Support–Ground Interaction of a Circular Tunnel Excavation

Authors: Yu-Lin Lee, Wen-Kuei Hsu, Po-Yu Chou, Pei-Wen Hsieh, Chi-Huang Ma, Wei-Cheng Kao

Source: Applied Sciences, Vol 12, Iss 4, p 1929 (2022)

Subject Terms: tunnel analysis, direct algorithmic process, support-ground interaction, confinement loss, Newton’s recursive method, convergence-confinement method, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/12/4/1929; https://doaj.org/toc/2076-3417

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Natural Product Isoliquiritigenin Activates GABAB Receptors to Decrease Voltage-Gate Ca2+ Channels and Glutamate Release in Rat Cerebrocortical Nerve Terminals

Authors: Tzu-Yu Lin, Cheng-Wei Lu, Pei-Wen Hsieh, Kuan-Ming Chiu, Ming-Yi Lee, Su-Jane Wang

Source: Biomolecules, Vol 11, Iss 10, p 1537 (2021)

Subject Terms: isoliquiritigenin, GABAB receptors, Gβγ, VGCCs, glutamate, cerebrocortical synaptosomes, Microbiology, QR1-502

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Relation: https://www.mdpi.com/2218-273X/11/10/1537; https://doaj.org/toc/2218-273X

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Polysaccharides from Kochia scoparia fruits protect mice from lipopolysaccharide-mediated acute lung injury by inhibiting neutrophil elastase

Authors: Yu-Li Chen, Tsong-Long Hwang, Jia-You Fang, Yu-Hsuan Lan, Kowit-Yu Chong, Pei-Wen Hsieh

Source: Journal of Functional Foods, Vol 38, Iss , Pp 582-590 (2017)

Subject Terms: Acute lung injury, Neutrophil elastase, Kochia scoparia fruits, Polysaccharide, Lipopolysaccharide (LPS), Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464617305844; https://doaj.org/toc/1756-4646

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HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases

Authors: Po-Hsiung Kung, Pei-Wen Hsieh, Ying-Ting Lin, Jia-Hau Lee, I-Hua Chen, Chin-Chung Wu

Source: Redox Biology, Vol 13, Iss C, Pp 266-277 (2017)

Subject Terms: HPW-RX40, Nitrostyrene, Protein disulfide isomerase, Platelets, Anti-thrombotic agents, Medicine (General), R5-920, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S221323171730246X; https://doaj.org/toc/2213-2317

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Identification of Potential Drug Targets of Broad-Spectrum Inhibitors with a Michael Acceptor Moiety Using Shotgun Proteomics

Authors: Hao-Wei Chu, Bidyadhar Sethy, Pei-Wen Hsieh, Jim-Tong Horng

Source: Viruses, Vol 13, Iss 9, p 1756 (2021)

Subject Terms: antiviral drug, influenza virus, itaconic acid, mass spectrometry, Michael addition, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/13/9/1756; https://doaj.org/toc/1999-4915

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Rosmarinic Acid, a Bioactive Phenolic Compound, Inhibits Glutamate Release from Rat Cerebrocortical Synaptosomes through GABAA Receptor Activation

Authors: Che-Chuan Wang, Pei-Wen Hsieh, Jinn-Rung Kuo, Su-Jane Wang

Source: Biomolecules, Vol 11, Iss 7, p 1029 (2021)

Subject Terms: rosmarinic acid, glutamate release, GABAA receptor, voltage-gated Ca2+ channel, CaMKII, synapsin I, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/11/7/1029; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/9b8a35a331004f86972d7b5e16d89807

A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction.

Authors: Nobuo Watanabe, Masako Kidokoro, Yusuke Suzuki, Makiko Tanaka, Shigeaki Inoue, Hideo Tsukamoto, Noriaki Hirayama, Pei-Wen Hsieh, Ching-Ping Tseng, Yoshihide Nakagawa, Sadaki Inokuchi

Source: PLoS ONE, Vol 14, Iss 9, p e0222331 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c54fab57e9d14e70b7d85211ec6bb248

Camptothecinoids from the seeds of Taiwanese Nothapodytes foetida

Authors: Yang-Chang Wu, Fang-Rong Chang, Tian-Shung Wu, Chi-Yu Lu, Shu-Li Chen, Chia-Lin Lee, Chin-Chung Wu, Pei-Wen Hsieh, Shou-Fang Wu

Source: Molecules, Vol 13, Iss 6, Pp 1361-1371 (2008)

Subject Terms: Nothapodytes foetida, 9-methoxy-18, 19-dehydrocamptothecin, 5-hydroxymappicine-mappicine-20-O-β-glucopyranoside, camptothecin, cytotoxicity, Organic chemistry, QD241-441

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Relation: http://www.mdpi.com/1420-3049/13/6/1361/; https://doaj.org/toc/1420-3049

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New Benzoyl Glucosides and Cytotoxic Pterosin Sesquiterpenes from Pteris ensiformis Burm.

Authors: Yang-Chang Wu, Ying-Chi Du, Ming-Jiuan Wu, Pei-Wen Hsieh, Mei-Chin Lu, Fang-Rong Chang, Yung-Husan Chen

Source: Molecules, Vol 13, Iss 2, Pp 255-266 (2008)

Subject Terms: Pteris ensiformis, pterosin B, human leukemia, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/13/2/255/; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/49a61151c11644b093bc08c0c90891de

The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.

Authors: Wen-Chin Chiu, Yi-Chen Lee, Yu-Han Su, Yen-Yun Wang, Chun-Hao Tsai, Yi-An Hou, Chie-Hong Wang, Ying-Fong Huang, Chih-Jen Huang, Shah-Hwa Chou, Pei-Wen Hsieh, Shyng-Shiou F Yuan

Source: PLoS ONE, Vol 11, Iss 11, p e0166453 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5119777?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e121801774df4aa7bf607344121f5790

Topical application of anthranilate derivatives ameliorates psoriatic inflammation in a mouse model by inhibiting keratinocyte-derived chemokine expression and neutrophil infiltration.

Authors: Zih-Chan Lin¹, Pei-Wen Hsieh^2,3,4,5, Tsong-Long Hwang^2,3,4,5,6, Chi-Yuan Chen^3,4,7,8, Sung, Calvin T.⁹, Jia-You Fang^2,3,4,5,6 fajy@mail.cgu.edu.tw

Source: FASEB Journal. Dec2018, Vol. 32 Issue 12, p6783-6795. 13p.

Design, synthesis & structure-activity relationships of a new class of antihuman enterovirus D68 & A71 agents.

Authors: Sethy, Bidyadhar, Chung-Fan Hsieh, Chieh Yeh, Jim-Tong Horng, Pei-Wen Hsieh

Source: Future Medicinal Chemistry; May2018, Vol. 10 Issue 11, p1333-1347, 15p

ß-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release.

Authors: Yao-Wen Chang, Ching-Ping Tseng, Chih-Hsun Lee, Tsong-Long Hwang, Yu-Li Chen, Mei-Tzu Su, Kowit-Yu Chong, Ying-Wei Lan, Chin-Chung Wu, Kung-Ju Chen, Fen-Hua Lu, Hsiang-Ruei Liao, Chuen Hsueh, Pei-Wen Hsieh

Source: American Journal of Physiology: Lung Cellular & Molecular Physiology; Apr2018, Vol. 314 Issue 4, pL654-L669, 16p, 2 Charts, 12 Graphs

CYT-Rx20 Inhibits Cervical Cancer Cell Growth and Migration Through Oxidative Stress-Induced DNA Damage, Cell Apoptosis, and Epithelial-to-Mesenchymal Transition Inhibition.

Authors: Yen-Yun Wang, Pei-Wen Hsieh, Yuk-Kwan Chen, Stephen Chu-Sung Hu, Ya-Ling Hsu, Chun-Hao Tsai, Yuan, Shyng-Shiou F.

Source: International Journal of Gynecological Cancer; Sep2017, Vol. 27 Issue 7, p1306-1317, 12p

Anti-melasma codrug of retinoic acid assists cutaneous absorption with attenuated skin irritation.

Authors: Pei-Wen Hsieh^1,2,3, Chi-Feng Hung⁴, Chih-Hung Lin⁵, Chang-Wei Huang⁶, Jia-You Fang^2,3,6,7 fajy@mail.cgu.edu.tw

Source: European Journal of Pharmaceutics & Biopharmaceutics. May2017, Vol. 114, p154-163. 10p.

Subject Terms: *MELANOSIS, *TRETINOIN, *SKIN absorption, *HYDROQUINONE, *DRUG side effects