PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis

Authors: Jokl, Elliot, Mullan, Aoibheann F., Simpson, Kara, Birchall, Lindsay, Pearmain, Laurence, Martin, Katherine, Pritchett, James, Raza, Sayyid, Shah, Rajesh, Hodson, Nigel W., Williams, Craig J., Camacho, Elizabeth, Zeef, Leo, Donaldson, Ian, Athwal, Varinder S., Hanley, Neil A., Piper Hanley, Karen

Source: In Cell Reports 28 November 2023 42(11)

P058 Persistence of neutrophil abnormalities in COVID-19 convalescence

Authors: Williams, Thomas O, Kästele, Verena, Mann, Elizabeth R, Knight, Sean B, Menon, Madhvi, Jagger, Christopher, Khan, Saba, Konkel, Joanne E, Shaw, Tovah N, Rattray, Magnus, Pearmain, Laurence, Horsley, Alexander, Ustianowski, Andrew, Prise, Ian, Bakerly, Nawar D, Dark, Paul M, Lord, Graham M, Simpson, Angela, Felton, Timothy, Ho, Ling-Pei, Feldmann, Marc, Bruce, Ian, Grainger, John R, Hussell, Tracy

Source: Rheumatology. 60(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144644584.0x000001&indx=1&recIds=ETOCvdc_100144644584.0x000001

Add-on therapy for pulmonary fibrosis, a forthcoming era with implications for practice: the BI 101550 and RELIEF trials.

Authors: Planas-Cerezales, Lurdes, Fabbri, Laura, Pearmain, Laurence

Source: Breathe; Sep2023, Vol. 19 Issue 3, p1-9, 9p

Rapid Generation of Pulmonary Organoids from Induced Pluripotent Stem Cells by Co-Culturing Endodermal and Mesodermal Progenitors for Pulmonary Disease Modelling.

Authors: Mitchell, Adam, Yu, Chaowen, Zhao, Xiangjun, Pearmain, Laurence, Shah, Rajesh, Hanley, Karen Piper, Felton, Timothy, Wang, Tao

Source: Biomedicines; May2023, Vol. 11 Issue 5, p1476, 17p

Subject Terms: INDUCED pluripotent stem cells, LUNG diseases, ORGANOIDS, EPIBLAST

Alterations in T and B cell function persist in convalescent COVID-19 patients

Authors: Ahmed, Rohan, Avery, Miriam, Birchall, Katharine, Charsley, Evelyn, Chenery, Alistair, Chew, Christine, Clark, Richard, Connolly, Emma, Connolly, Karen, Dawson, Simon, Durrans, Laura, Durrington, Hannah, Egan, Jasmine, Filbey, Kara, Fox, Claire, Francis, Helen, Franklin, Miriam, Glasgow, Susannah, Godfrey, Nicola, Gray, Kathryn J., Grundy, Seamus, Guerin, Jacinta, Hackney, Pamela, Hayes, Chantelle, Hardy, Emma, Harris, Jade, John, Anu, Jolly, Bethany, Kästele, Verena, Kerry, Gina, Lui, Sylvia, Lin, Lijing, Mathioudakis, Alex G., Mitchell, Joanne, Moizer, Clare, Moore, Katrina, Moss, Stuart, Baker, Syed Murtuza, Oliver, Rob, Padden, Grace, Parkinson, Christina, Phuycharoen, Michael, Saha, Ananya, Salcman, Barbora, Scott, Nicholas A., Sharma, Seema, Shaw, Jane, Shaw, Joanne, Shepley, Elizabeth, Smith, Lara, Stephan, Simon, Stephens, Ruth, Tavernier, Gael, Tudge, Rhys, Wareing, Louis, Warren, Roanna, Williams, Thomas, Willmore, Lisa, Younas, Mehwish, Shuwa, Halima A., Shaw, Tovah N., Knight, Sean B., Wemyss, Kelly, McClure, Flora A., Pearmain, Laurence, Prise, Ian, Jagger, Christopher, Morgan, David J., Khan, Saba, Brand, Oliver, Mann, Elizabeth R., Ustianowski, Andrew, Bakerly, Nawar Diar, Dark, Paul, Brightling, Christopher E., Brij, Seema, Felton, Timothy, Simpson, Angela, Grainger, John R., Hussell, Tracy, Konkel, Joanne E., Menon, Madhvi

Source: In Med 11 June 2021 2(6):720-735

Lessons of the month 1: Salbutamol induced lactic acidosis: clinically recognised but often forgotten.

Authors: Pearmain, Laurence^1,2,3 laurencepearmain@nhs.net, Gupta, Ravi⁴, Bright-Thomas, Rowland J.^5,6

Source: Clinical Medicine. Jan2020, Vol. 20 Issue 1, p101-104. 4p.

Subject Terms: *ALBUTEROL, *ASTHMA, *COUGH, *DYSPNEA, *LACTATES, *RESPIRATORY organ sounds, *COMORBIDITY, *LACTIC acidosis, *POLYPHARMACY

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Persistent air leak after pulmonary transplantation.

Authors: Pearmain, Laurence, Krysiak, Piotr, Blaikley, John, Alaloul, Mohamed

Source: BMJ Case Reports; 7/27/2017, Vol. 2017, p1-3, 3p, 2 Color Photographs, 1 Black and White Photograph

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Alterations in T and B cell function persist in convalescent COVID-19 patients

Authors: Shuwa, Halima A., Shaw, Tovah N., Knight, Sean B., Wemyss, Kelly, McClure, Flora A., Pearmain, Laurence, Prise, Ian, Jagger, Christopher, Morgan, David.J., Khan, Saba, Brand, Oliver, Mann, Elizabeth R., Ustianowski, Andrew, Bakerly, Nawar Diar, Dark, Paul, Brightling, Christopher E., Brij, Seema, Felton, Timothy, Simpson, Angela, Grainger, John R., Hussell, Tracy, Konkel, Joanne E., Menon, Madhvi

Source: Med; 20210101, Issue: Preprints