Efficacy and Safety of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting Transforming Growth Factor-β and Programmed Death-Ligand 1, Plus Chemotherapy in Patients With Stage IV NSCLC

Authors: Rolfo, Christian ^{a, b, ∗}, Greillier, Laurent ^c, Veillon, Remi ^d, Badin, Firas ^e, Ghiringhelli, Francois ^f, Isambert, Nicolas ^g, Paulus, Astrid ^h, Chaudhary, Surendra Pal ⁱ, Vugmeyster, Yulia ⁱ, Sato, Masashi ^j, Hiret, Sandrine ^k

Source: In JTO Clinical and Research Reports January 2025 6(1)

Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection

Authors: Calmes, Doriane, Graff, Sophie, Maes, Nathalie, Frix, Anne-Noëlle, Thys, Marie, Bonhomme, Olivier, Berg, Julien, Debruche, Mathieu, Gester, Fanny, Henket, Monique, Paulus, Virginie, Duysinx, Bernard, Heinen, Vincent, Dang, Delphine Nguyen, Paulus, Astrid, Quaedvlieg, Valérie, Vaillant, Frederique, Van Cauwenberge, Hélène, Malaise, Michel, Gilbert, Alisson, Ghuysen, Alexandre, Gillet, Pierre, Moutschen, Michel, Misset, Benoit, Sibille, Anne, Guiot, Julien, Corhay, Jean-Louis, Louis, Renaud, Schleich, Florence

Source: In The Journal of Allergy and Clinical Immunology: In Practice January 2021 9(1):160-169

Pooled safety analysis and management of sotorasib-related adverse events in KRAS G12C-mutated advanced non-small cell lung cancer.

Authors: Skoulidis, Ferdinandos, Li, Bob T, Hochmair, Maximilian, Govindan, Ramaswamy, Vincent, Mark, Wekken, Anthonie J van der, Aransay, Noemi Reguart, O'Byrne, Kenneth J, Girard, Nicolas, Griesinger, Frank, Nishio, Makoto, Häfliger, Simon, Lindsay, Colin, Reinmuth, Niels, Paulus, Astrid, Papakotoulas, Pavlos, Kim, Sang-We, Ferreira, Carlos Gil, Pasello, Giulia, Duruisseaux, Michael

Source: Oncologist; Jan2025, Vol. 30 Issue 1, p1-10, 10p

Subject Terms: DIARRHEA, PNEUMONIA, PATIENT safety, RESEARCH funding, DRUG side effects, HEPATOTOXICOLOGY, LONG QT syndrome, ANTINEOPLASTIC agents, ASPARTATE aminotransferase, CANCER patients, INTERSTITIAL lung diseases, CAUSES of death, ALANINE aminotransferase, LUNG cancer, GENETIC mutation, DISEASE incidence, NAUSEA, DISEASE progression

Radiomics and Delta-Radiomics Signatures to Predict Response and Survival in Patients with Non-Small-Cell Lung Cancer Treated with Immune Checkpoint Inhibitors.

Authors: Cousin, François, Louis, Thomas, Dheur, Sophie, Aboubakar, Frank, Ghaye, Benoit, Occhipinti, Mariaelena, Vos, Wim, Bottari, Fabio, Paulus, Astrid, Sibille, Anne, Vaillant, Frédérique, Duysinx, Bernard, Guiot, Julien, Hustinx, Roland

Source: Cancers; Apr2023, Vol. 15 Issue 7, p1968, 14p

Subject Terms: LUNG cancer, SURVIVAL, IMMUNE checkpoint inhibitors, PROGRAMMED death-ligand 1, CONFIDENCE intervals, RETROSPECTIVE studies, CONTRAST media, RANDOM forest algorithms, DESCRIPTIVE statistics, COMPUTED tomography, DATA analysis software, IMMUNOTHERAPY, PROPORTIONAL hazards models

Oncological patients' reactions to COVID‐19 pandemic: A single institution prospective study.

Authors: Onesti, Concetta Elisa, Schroeder, Hélène, Rorive, Andrée, Sautois, Brieuc, Lecocq, Marie, Goffin, Marie, Gonne, Elodie, Collinge, Astrid, Nicolaers, Laurence, Wéra, Odile, Catot, Amandine, Loly, Catherine, Paulus, Astrid, Sibille, Anne, Lousberg, Laurence, Troisfontaine, Florence, Collignon, Joëlle, Gennigens, Christine, Frères, Pierre, Polus, Marc

Source: Cancer Reports; Oct2022, Vol. 5 Issue 10, p1-9, 9p

Killing Two Birds With One Stone: Effective Control of Both Non-Small Cell Lung Cancer and Progressive Multifocal Leukoencephalopathy With Atezolizumab, A Case Report.

Authors: Lambert, Nicolas, El Moussaoui, Majdouline, Ritacco, Caroline, Moïse, Martin, Paulus, Astrid, Delvenne, Philippe, Baron, Frédéric, Sadzot, Bernard, Maquet, Pierre

Source: Frontiers in Immunology; 5/3/2022, Vol. 13, p1-6, 6p

Subject Terms: PROGRESSIVE multifocal leukoencephalopathy, NON-small-cell lung carcinoma, ATEZOLIZUMAB, IMMUNE checkpoint inhibitors, JOHN Cunningham virus, OPPORTUNISTIC infections, LEUKOENCEPHALOPATHIES

Efficacy and Safety of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting Transforming Growth Factor-β and Programmed Death-Ligand 1, Plus Chemotherapy in Patients With Stage IV NSCLC

Authors: Rolfo, Christian, Greillier, Laurent, Veillon, Remi, Badin, Firas, Ghiringhelli, Francois, Isambert, Nicolas, Paulus, Astrid, Chaudhary, Surendra Pal, Vugmeyster, Yulia, Sato, Masashi, Hiret, Sandrine

Source: JTO Clinical and Research Reports; 20240101, Issue: Preprints

Intracranial efficacy of sotorasib versus docetaxel in pretreated KRAS G12C-mutated advanced non-small cell lung cancer (NSCLC): Practice-informing data from a global, phase 3, randomized, controlled trial (RCT).

Authors: Dingemans, Anne-Marie C., Syrigos, Konstantinos, Livi, Lorenzo, Paulus, Astrid, Kim, Sang-We, Chen, Yuanbin, Felip, Enriqueta, Griesinger, Frank, Ohashi, Kadoaki, Zalcman, Gerard, Hughes, Brett Gordon Maxwell, Sorensen, Jens Benn, Blais, Normand, Ferreira, Carlos G. M., Lindsay, Colin R, Dziadziuszko, Rafal, Ward, Patrick J., Obiozor, Cynthia Chinedu, Wang, Yang, Peters, Solange

Source: Journal of Clinical Oncology; 6/10/2023 Supplement17, Vol. 41, pLBA9016-LBA9016, 1p

Safety, efficacy and biomarker data in patients with non-small cell lung cancer treated with the anti-IL1RAP antibody nadunolimab in combination with platinum doublet.

Authors: Paz-Ares, Luis G., Paulus, Astrid, Zemaitis, Marius, Cicenas, Saulius, Zvirbule, Zanete, Felip, Enriqueta, Sanfridson, Annika, Rydberg-Millrud, Camilla, Magnusson, Susanne, Losic, Nedjad, Garcia-Ribas, Ignacio

Source: Journal of Clinical Oncology; 2023 Supplement 16, Vol. 41, p9089-9089, 1p

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