PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing

Authors: Alyssa N. Obermayer, Darwin Chang, Gabrielle Nobles, Mingxiang Teng, Aik-Choon Tan, Xuefeng Wang, Y. Ann Chen, Steven Eschrich, Paulo C. Rodriguez, G. Daniel Grass, Soheil Meshinchi, Ahmad Tarhini, Dung-tsa Chen, Timothy I. Shaw

Source: BMC Bioinformatics, Vol 24, Iss 1, Pp 1-14 (2023)

Subject Terms: Pathway-level survival analysis, R Shiny app, Hazard ratio GSEA, Pathway clustering, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/a8a184167ea846a0a4bc7b36d14d1a13

Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer

Authors: Nada H. Eisa, Vincent M. Crowley, Asif Elahi, Vamsi Krishna Kommalapati, Michael A. Serwetnyk, Taoufik Llbiyi, Sumin Lu, Kashish Kainth, Yasmeen Jilani, Daniela Marasco, Abdeljabar El Andaloussi, Sukyeong Lee, Francis T.F. Tsai, Paulo C. Rodriguez, David Munn, Esteban Celis, Hasan Korkaya, Abdessamad Debbab, Brian Blagg, Ahmed Chadli

Source: iScience, Vol 26, Iss 12, Pp 108308- (2023)

Subject Terms: Microenvironment, Biological sciences, Molecular biology, Cancer, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223023854; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/f4ba062b1eb84919b99e30fb877c3d61

Increased inflammatory low-density neutrophils in severe obesity and effect of bariatric surgery: Results from case-control and prospective cohort studies

Authors: Maria Dulfary Sanchez-Pino, William S. Richardson, Jovanny Zabaleta, Ramesh Thylur Puttalingaiah, Andrew G. Chapple, Jiao Liu, Yonghyan Kim, Michelle Ponder, Randi DeArmitt, Lyndsey Buckner Baiamonte, Dorota Wyczechowska, Liqin Zheng, Amir A. Al-Khami, Jone Garai, Rachel Martini, Melissa Davis, Jessica Koller Gorham, James B. Wooldridge, Paulo C. Rodriguez, Lucio Miele, Augusto C. Ochoa

Source: EBioMedicine, Vol 77, Iss , Pp 103910- (2022)

Subject Terms: Obesity, Bariatric surgery, Low-density neutrophils, LDN, Inflammation, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396422000949; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/4873f6cb4f564de8931064266165af9b

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

Authors: Miao Yu, Gang Guo, Lei Huang, Libin Deng, Chang-Sheng Chang, Bhagelu R. Achyut, Madison Canning, Ningchun Xu, Ali S. Arbab, Roni J. Bollag, Paulo C. Rodriguez, Andrew L. Mellor, Huidong Shi, David H. Munn, Yan Cui

Source: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3a939ed9e1ba46adb3d1e889423e5b4d

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Authors: Yu Cao, Jimena Trillo-Tinoco, Rosa A. Sierra, Carmen Anadon, Wenjie Dai, Eslam Mohamed, Ling Cen, Tara L. Costich, Anthony Magliocco, Douglas Marchion, Richard Klar, Sven Michel, Frank Jaschinski, Richard R. Reich, Shikhar Mehrotra, Juan R. Cubillos-Ruiz, David H. Munn, Jose R. Conejo-Garcia, Paulo C. Rodriguez

Source: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f05c7d9780cc4100b5638fc324c1bb21

Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

Authors: Claudia Sorrentino, Fokhrul Hossain, Paulo C. Rodriguez, Rosa A. Sierra, Antonio Pannuti, Stephen Hatfield, Barbara A. Osborne, Lisa M. Minter, Lucio Miele, Silvana Morello

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: adenosine, A2A adenosine receptor (A2AR), Notch1, CD8+T-cells, immunosuppression, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00935/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/241eb176dc6b4d0f96316fe01988e3c4

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

Authors: Vincenzo Bronte, Sven Brandau, Shu-Hsia Chen, Mario P. Colombo, Alan B. Frey, Tim F. Greten, Susanna Mandruzzato, Peter J. Murray, Augusto Ochoa, Suzanne Ostrand-Rosenberg, Paulo C. Rodriguez, Antonio Sica, Viktor Umansky, Robert H. Vonderheide, Dmitry I. Gabrilovich

Source: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7c32c093ca484097b5efdfd00dee7e64

Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

Authors: Claudia Sorrentino, Fokhrul Hossain, Paulo C. Rodriguez, Rosa A. Sierra, Antonio Pannuti, Stephen Hatfield, Barbara A. Osborne, Lisa M. Minter, Lucio Miele, Silvana Morello

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: adenosine, A2A adenosine receptor (A2AR), Notch1, CD8+T-cells, immunosuppression, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00162/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/03798900c2a24384a59550c33bc67f4b

Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity

Authors: Brian C. Betts, Frederick L. Locke, Elizabeth M. Sagatys, Joseph Pidala, Kelly Walton, Meghan Menges, Jordan Reff, Asim Saha, Julie Y. Djeu, John V. Kiluk, Marie C. Lee, Jongphil Kim, Chang Won Kang, Chih-Hang Anthony Tang, Jeremy Frieling, Conor C. Lynch, Alan List, Paulo C. Rodriguez, Bruce R. Blazar, Jose R. Conejo-Garcia, Juan R. Del Valle, Chih-Chi Andrew Hu, Claudio Anasetti

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: GvHD, GvL, er stress, XBP-1S, dendritic cell (DC), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.02887/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/d7d53dab35a0449b90de1bf45bb8064e

Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses

Authors: Fokhrul Hossain, Samarpan Majumder, Deniz A. Ucar, Paulo C. Rodriguez, Todd E. Golde, Lisa M. Minter, Barbara A. Osborne, Lucio Miele

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: Notch, cancer, immunity, cellular, inflammation, myeloid cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01288/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/43007cad3d39406fad720a3813534bd6

Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells

Authors: Amir A. Al-Khami, Liqin Zheng, Luis Del Valle, Fokhrul Hossain, Dorota Wyczechowska, Jovanny Zabaleta, Maria D. Sanchez, Matthew J. Dean, Paulo C. Rodriguez, Augusto C. Ochoa

Source: OncoImmunology, Vol 6, Iss 10 (2017)

Subject Terms: immunometabolism, immune suppression, lipids, mdsc, tumor microenvironment, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/97ed5a14467f44df9489ae61540b1637

Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Authors: Yu Cao, Jimena Trillo-Tinoco, Rosa A. Sierra, Carmen Anadon, Wenjie Dai, Eslam Mohamed, Ling Cen, Tara L. Costich, Anthony Magliocco, Douglas Marchion, Richard Klar, Sven Michel, Frank Jaschinski, Richard R. Reich, Shikhar Mehrotra, Juan R. Cubillos-Ruiz, David H. Munn, Jose R. Conejo-Garcia, Paulo C. Rodriguez

Source: Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/abe981cf7a3943d19915317c7bf25947

Implementing the Computer-Supported Collaborative Learning and Teaching in a Statistics Class for the Engineering Students.

Authors: Rohmatul Fajriyah, Paulo C. Rodriguez

Source: Journal of Physics: Conference Series; 2018, Vol. 1028 Issue 1, p1-1, 1p

Differential requirements for CD4+ T cells in the efficacy of the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain metastasis models

Authors: Paulo C Rodriguez, Zhihua Chen, Y Ann Chen, Lilit Karapetyan, Jiannong Li, Manali S Phadke, Jessica K Mandula, Peter A Forsyth, Keiran S M Smalley

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/11/12/e007239.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/4d56c2e227884da39b33d1663c170b41

151 Genetic heterogeneity between paired primary and metastatic solid tumors and implications for neoantigen-based personalized cancer vaccines

Authors: Xuefeng Wang, Igor Puzanov, Abdul Rafeh Naqash, Paulo C Rodriguez, George J Weiner, Jose Conejo-Garcia, Jamie Teer, Xiaoqing Yu, Margaret E Gatti-Mays, William Dalton, Howard Colman, Aik Choon Tan, Timothy I Shaw, Darwin Chang, Alyssa Obermayer, Dale Hedges, Aakrosh Ratan, Martin D McCarter, John Carpten, Susanne M Arnold, Michelle Churchman

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/0258ce1216ab4d38926536bfebfd3189