Upregulation of keratin 15 is required for varicella-zoster virus replication in keratinocytes and is attenuated in the live attenuated vOka vaccine strain

Authors: Cristina Tommasi, Ohad Yogev, Michael B. Yee, Andriani Drousioti, Meleri Jones, Alice Ring, Manuraj Singh, Inga Dry, Oscar Atkins, Aishath S. Naeem, Nisha Kriplani, Arne N. Akbar, Jürgen G. Haas, Edel A. O’Toole, Paul R. Kinchington, Judith Breuer

Source: Virology Journal, Vol 21, Iss 1, Pp 1-11 (2024)

Subject Terms: VZV, KRT15, IE62, vOka vaccine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1743-422X

Access URL: https://doaj.org/article/09112decde4b4fc2923182d25e256520

Viral modulation of type II interferon increases T cell adhesion and virus spread

Authors: Carina Jacobsen, Nina Plückebaum, George Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A. Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R. Kinchington, Nico Lachmann, Daniel P. Depledge, Thomas Krey, Abel Viejo-Borbolla

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0569487febc14ccf86b8f547b6011d69

Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2

Authors: James McNulty, Chanti Babu-Dokuburra, Jon Scattolon, Carlos Zepeda-Velazquez, Maribeth A. Wesesky, Jill K. Caldwell, Wenxiao Zheng, Jadranka Milosevic, Paul R. Kinchington, David C. Bloom, Vishwajit L. Nimgaonkar, Leonardo D’Aiuto

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/27af499616bc42268d26cedeb59add2c

Sex Differences in the Role of Neurexin 3α in Zoster Associated Pain

Authors: Phillip R. Kramer, Mikhail Umorin, Rebecca Hornung, M. Douglas Benson, Paul R. Kinchington

Source: Frontiers in Integrative Neuroscience, Vol 16 (2022)

Subject Terms: orofacial, zoster, shingles, GABA, GABAergic, post-herpetic neuralgia, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnint.2022.915797/full; https://doaj.org/toc/1662-5145

Access URL: https://doaj.org/article/41ae63a624cd4ddb9e5e160e03683021

The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids

Authors: Leonardo D’Aiuto, Jill K. Caldwell, Callen T. Wallace, Tristan R. Grams, Maribeth A. Wesesky, Joel A. Wood, Simon C. Watkins, Paul R. Kinchington, David C. Bloom, Vishwajit L. Nimgaonkar

Source: Cells, Vol 11, Iss 22, p 3539 (2022)

Subject Terms: brain organoids, herpes simplex virus (HSV), human induced pluripotent stem cells (hiPSCs), neural rosettes, neonatal herpes encephalitis, acyclovir resistance, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/22/3539; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/3e1e0d48f52b43589d053a8362073025

Local Immune Control of Latent Herpes Simplex Virus Type 1 in Ganglia of Mice and Man

Authors: Anthony J. St. Leger, David M. Koelle, Paul R. Kinchington, Georges Michel G. M. Verjans

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: HSV-1, latency, ganglion, mouse, human, intrinsic immunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.723809/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/0e199e00dce443458b977777b454dded

Studies of Infection and Experimental Reactivation by Recombinant VZV with Mutations in Virally-Encoded Small Non-Coding RNA

Authors: Punam Bisht, Biswajit Das, Tatiana Borodianskiy-Shteinberg, Paul R. Kinchington, Ronald S. Goldstein

Source: Viruses, Vol 14, Iss 5, p 1015 (2022)

Subject Terms: varicella zoster virus, latency, reactivation, human neuron culture, non-coding RNA, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/5/1015; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/a3837512b64f4d74a5f7249c15a7f320

Development of Robust Varicella Zoster Virus Luciferase Reporter Viruses for In Vivo Monitoring of Virus Growth and Its Antiviral Inhibition in Culture, Skin, and Humanized Mice

Authors: Megan G. Lloyd, Michael B. Yee, Joseph S. Flot, Dongmei Liu, Brittany W. Geiler, Paul R. Kinchington, Jennifer F. Moffat

Source: Viruses, Vol 14, Iss 4, p 826 (2022)

Subject Terms: varicella-zoster virus, antiviral drugs, bacterial artificial chromosome, luciferase, bioluminescence imaging, skin organ culture, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/4/826; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/396dff2fd53c4aea84767c2f6dc1fa9a

Antiviral Targeting of Varicella Zoster Virus Replication and Neuronal Reactivation Using CRISPR/Cas9 Cleavage of the Duplicated Open Reading Frames 62/71

Authors: Betty W. Wu, Michael B. Yee, Ronald S. Goldstein, Paul R. Kinchington

Source: Viruses, Vol 14, Iss 2, p 378 (2022)

Subject Terms: varicella zoster virus, latency, reactivation, genome cleavage, CRISPR/Cas9, AAV, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/2/378; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/b43893a0df5845f99ea92527408609eb

Sex differences underlying orofacial varicella zoster associated pain in rats

Authors: Crystal Stinson, Mohong Deng, Michael B Yee, Larry L. Bellinger, Paul R. Kinchington, Phillip R. Kramer

Source: BMC Neurology, Vol 17, Iss 1, Pp 1-15 (2017)

Subject Terms: Post-herpetic neuralgia, Shingles, Chickenpox, Trigeminal ganglia, Orofacial, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12883-017-0882-6; https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/1e32af60f9524c45a8df1f5d2a5f6fe4

Virus-Mediated Suppression of the Antigen Presentation Molecule MR1

Authors: Brian P. McSharry, Carolyn Samer, Hamish E.G. McWilliam, Caroline L. Ashley, Michael B. Yee, Megan Steain, Ligong Liu, David P. Fairlie, Paul R. Kinchington, James McCluskey, Allison Abendroth, Jose A. Villadangos, Jamie Rossjohn, Barry Slobedman

Source: Cell Reports, Vol 30, Iss 9, Pp 2948-2962.e4 (2020)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720301716; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/8166c32232ce4ae29169a6ca737613b4

Modeling Varicella Zoster Virus Persistence and Reactivation – Closer to Resolving a Perplexing Persistent State

Authors: Lillian Laemmle, Ronald S. Goldstein, Paul R. Kinchington

Source: Frontiers in Microbiology, Vol 10 (2019)

Subject Terms: varicella zoster virus, latency, reactivation, animal models, human neuron culture models, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2019.01634/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/a3eeace1a12a46fb911de33ed14766c2

Corrigendum: Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus

Authors: Phillip R. Kramer, Mahesh Rao, Crystal Stinson, Larry L. Bellinger, Paul R. Kinchington, Michael B. Yee

Source: Frontiers in Integrative Neuroscience, Vol 12 (2019)

Subject Terms: orofacial, herpes zoster, neuralgia, shingles, pain, estrogen, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnint.2018.00066/full; https://doaj.org/toc/1662-5145

Access URL: https://doaj.org/article/cbeb1124bcfe45e19f7d1186b9bc00f7

Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus

Authors: Phillip R. Kramer, Mahesh Rao, Crystal Stinson, Larry L. Bellinger, Paul R. Kinchington, Michael B. Yee

Source: Frontiers in Integrative Neuroscience, Vol 12 (2018)

Subject Terms: orofacial, herpes zostr, neuralgia, shingles, pain, estrogen, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnint.2018.00046/full; https://doaj.org/toc/1662-5145

Access URL: https://doaj.org/article/5104101c44a04e9583a69eaf1b401d12

Role for the Ventral Posterior Medial/Posterior Lateral Thalamus and Anterior Cingulate Cortex in Affective/Motivation Pain Induced by Varicella Zoster Virus

Authors: Phillip R. Kramer, Jennifer Strand, Crystal Stinson, Larry L. Bellinger, Paul R. Kinchington, Michael B. Yee, Mikhail Umorin, Yuan B. Peng

Source: Frontiers in Integrative Neuroscience, Vol 11 (2017)

Subject Terms: ventral posterolateral nucleus, ventral posteromedial nucleus, anterior cingulate cortex, orofacial pain, varicella zoster virus, shingles, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fnint.2017.00027/full; https://doaj.org/toc/1662-5145

Access URL: https://doaj.org/article/4573bbc08dfe4d74b6dd651d9af38ffb

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Immune Control of HSV-1 Latency.

Authors: Vilma Decman, Michael L. Freeman, Paul R. Kinchington, Robert L. Hendricks

Source: Viral Immunology; Fall2005, Vol. 18 Issue 3, p466-473, 8p

Prospects for adenovirus antivirals.

Authors: Paul R. Kinchington, Eric G. Romanowski, Y. Jerold Gordon

Source: Journal of Antimicrobial Chemotherapy (JAC); Apr2005, Vol. 55 Issue 4, p424-429, 6p

Subject Terms: COMMUNICABLE diseases, GASTROINTESTINAL system, KERATOCONJUNCTIVITIS, IMMUNE system

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