Early, precise, and safe clinical evaluation of the pharmacodynamic effects of novel agents in the intact human tumor microenvironment

Authors: Kenneth R. Gundle, Karthik Rajasekaran, Jeffrey Houlton, Gary B. Deutsch, Thomas J. Ow, Robert G. Maki, John Pang, Cherie-Ann O. Nathan, Daniel Clayburgh, Jason G. Newman, Elyse Brinkmann, Michael J. Wagner, Seth M. Pollack, Matthew J. Thompson, Ryan J. Li, Vikas Mehta, Bradley A. Schiff, Barry I. Wenig, Paul L. Swiecicki, Alice L. Tang, Jessica L. Davis, Annemieke van Zante, Jessica A. Bertout, Wendy Jenkins, Atticus Turner, Marc Grenley, Connor Burns, Jason P. Frazier, Angela Merrell, Kimberly H. W. Sottero, Jonathan M. J. Derry, Kate C. Gillespie, Bre Mills, Richard A. Klinghoffer

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: phase 0, intratumoral microdosing, spatial profiling, multidrug analyses, pharmacodynamics, tumor microenvironment, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1367581/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/df356ddd88154387999a5c867f337370

Imaging response assessment for predicting outcomes after bioselection chemotherapy in larynx cancer: A secondary analysis of two prospective trials

Authors: Laila A. Gharzai, Julia Pakela, Elizabeth M. Jaworski, Issam El Naqa, Jennifer Shah, Peter G. Hawkins, Matthew E. Spector, Carol R. Bradford, Steven B. Chinn, Kelly Malloy, Robbi Kupfer, Andrew Shuman, Robert Morrison, Chaz L. Stucken, Andrew Rosko, Mark E. Prince, Keith Casper, Avraham Eisbruch, Gregory Wolf, Paul L. Swiecicki, Francis Worden, Michelle L. Mierzwa

Source: Clinical and Translational Radiation Oncology, Vol 33, Iss , Pp 30-36 (2022)

Subject Terms: Locally advanced laryngeal cancer, Bioselection imaging, Chemoradiation, Laryngectomy, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405630821001051; https://doaj.org/toc/2405-6308

Access URL: https://doaj.org/article/36489a02909c47fdb394460ab8d41d1e

Trans-Renal Cell-Free Tumor DNA for Urine-Based Liquid Biopsy of Cancer

Authors: Sarah M. Dermody, Chandan Bhambhani, Paul L. Swiecicki, J. Chad Brenner, Muneesh Tewari

Source: Frontiers in Genetics, Vol 13 (2022)

Subject Terms: trans-renal, liquid biopsy, cell-free DNA, circulating tumor DNA, ctDNA, urine, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2022.879108/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/e181a5e91acf4b5293f3aa981760392d

Patient and Provider Perspectives on Enrollment in Precision Oncology Research: Qualitative Ethical Analysis

Authors: Kayte Spector-Bagdady, Madison Kent, Chris D Krenz, Collin Brummel, Paul L Swiecicki, J Chad Brenner, Andrew G Shuman

Source: JMIR Cancer, Vol 8, Iss 2, p e35033 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://cancer.jmir.org/2022/2/e35033; https://doaj.org/toc/2369-1999

Access URL: https://doaj.org/article/259028fd7d794d15bd441ee986744e24