VEXAS, Chediak–Higashi syndrome and Danon disease: myeloid cell endo-lysosomal pathway dysfunction as a common denominator?

Authors: Coline Savy, Maxence Bourgoin, Thomas Cluzeau, Arnaud Jacquel, Guillaume Robert, Patrick Auberger

Source: Cellular & Molecular Biology Letters, Vol 30, Iss 1, Pp 1-14 (2025)

Subject Terms: VEXAS, Chediak–Higashi disease, Danon disease, Lysosomes, pH, Neutrophiles, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1689-1392

Access URL: https://doaj.org/article/dd8ae773e8d64cb0861c28808b5281ed

PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression

Authors: Marion Haas, Sabrina Cherfa, Léa Nguyen, Maxence Bourgoin, Gersende Caron, Elise Dessauge, Tony Marchand, Laurent Delpy, Patrick Auberger, Jérôme Moreaux, Arnaud Jacquel, Thierry Fest

Source: Nature Communications, Vol 16, Iss 1, Pp 1-20 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/33d5135d0b5e45fe979dee3641915203

Emerging role of glutathione peroxidase 4 in myeloid cell lineage development and acute myeloid leukemia

Authors: Patrick Auberger, Cécile Favreau, Coline Savy, Arnaud Jacquel, Guillaume Robert

Source: Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-15 (2024)

Subject Terms: GPX4, Ferroptosis, Myeloid differentiation, Myeloid leukemia, AML, Small molecule inhibitors, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1689-1392

Access URL: https://doaj.org/article/13144bc4693b42e1967ff459c25f9d24

Unveiling CXCR2 as a promising therapeutic target in renal cell carcinoma: exploring the immunotherapeutic paradigm shift through its inhibition by RCT001

Authors: Christopher Montemagno, Arnaud Jacquel, Charlotte Pandiani, Olivia Rastoin, Rosie Dawaliby, Thomas Schmitt, Maxence Bourgoin, Héliciane Palenzuela, Anne-Laure Rossi, Damien Ambrosetti, Jerome Durivault, Frederic Luciano, Delphine Borchiellini, Julie Le Du, Leticia Christina Pires Gonçalves, Patrick Auberger, Rachid Benhida, Lisa Kinget, Benoit Beuselinck, Cyril Ronco, Gilles Pagès, Maeva Dufies

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)

Subject Terms: Renal Cell Carcinoma, M2 tumor associated macrophages, Immunotherapies resistance, CXCR2 inhibitors, Nivolumab, Ipilimumab, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/2ff8f539d4e9454cb864905303b22e6e

Real‐life challenges using personalized prognostic scoring systems in acute myeloid leukemia

Authors: Anne Calleja, Michael Loschi, Laurent Bailly, Adeline Morisot, Alice Marceau, Lionel Mannone, Guillaume Robert, Patrick Auberger, Claude Preudhomme, Sophie Raynaud, Fabien Subtil, Pierre Sujobert, Thomas Cluzeau

Source: Cancer Medicine, Vol 12, Iss 5, Pp 5656-5660 (2023)

Subject Terms: acute myeloid leukemia, mutations, personalized medicine, prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/d992efe825594a8d9a57c31cda98a4ed

The generation, activation, and polarization of monocyte-derived macrophages in human malignancies

Authors: Paul Chaintreuil, Emeline Kerreneur, Maxence Bourgoin, Coline Savy, Cécile Favreau, Guillaume Robert, Arnaud Jacquel, Patrick Auberger

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: monocyte-derived macrophages, CSF-1, differentiation, polarization, TAM, LAM, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178337/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f5d1ea3aaa86476ab6e66bd573b42a17

Plk1, upregulated by HIF-2, mediates metastasis and drug resistance of clear cell renal cell carcinoma

Authors: Maeva Dufies, Annelies Verbiest, Lindsay S. Cooley, Papa Diogop Ndiaye, Xingkang He, Nicolas Nottet, Wilfried Souleyreau, Anais Hagege, Stephanie Torrino, Julien Parola, Sandy Giuliano, Delphine Borchiellini, Renaud Schiappa, Baharia Mograbi, Jessica Zucman-Rossi, Karim Bensalah, Alain Ravaud, Patrick Auberger, Andréas Bikfalvi, Emmanuel Chamorey, Nathalie Rioux-Leclercq, Nathalie M. Mazure, Benoit Beuselinck, Yihai Cao, Jean Christophe Bernhard, Damien Ambrosetti, Gilles Pagès

Source: Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/9cd5ec5c631f454a824bec657b006c8d

A new ChEMBL dataset for the similarity-based target fishing engine FastTargetPred: Annotation of an exhaustive list of linear tetrapeptides

Authors: Shivalika Tanwar, Patrick Auberger, Germain Gillet, Mario DiPaola, Katya Tsaioun, Bruno O. Villoutreix

Source: Data in Brief, Vol 42, Iss , Pp 108159- (2022)

Subject Terms: Peptide, Virtual screening, Drug discovery, Target prediction, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352340922003638; https://doaj.org/toc/2352-3409

Access URL: https://doaj.org/article/6e535296d326447eb4efea2ac8a595bb

Reprogramming monocyte-derived macrophages through caspase inhibition

Authors: Paul Chaintreuil, Lucie Laplane, Florian Esnault, Victoria Ghesquier, Coline Savy, Nathan Furstoss, Marie-Laure Arcangeli, Thomas Cluzeau, Guillaume Robert, Nathalie Droin, Eric Solary, Patrick Auberger, Arnaud Jacquel

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: primary monocyte, monocyte-derived macrophages, differentiation, polarization, csf-1, caspases, emricasan, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/2e4cff75610744d89d531509ca632a79

Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies

Authors: Aicha Talha, Cécile Favreau, Maxence Bourgoin, Guillaume Robert, Patrick Auberger, Lahcen EL Ammari, Mohamed Saadi, Rachid Benhida, Anthony R. Martin, Khalid Bougrin

Source: Ultrasonics Sonochemistry, Vol 78, Iss , Pp 105748- (2021)

Subject Terms: Sulfonamides-Isoxazolines, One-pot synthesis, Radical processes, Ultrasound, Hematological Malignancies, Chemistry, QD1-999, Acoustics. Sound, QC221-246

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S135041772100290X; https://doaj.org/toc/1350-4177

Access URL: https://doaj.org/article/0a11e89dc26241afa4ec9f48c62888db

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms

Authors: Manon Viaud, Omar Abdel-Wahab, Julie Gall, Stoyan Ivanov, Rodolphe Guinamard, Sophie Sore, Johanna Merlin, Marion Ayrault, Emma Guilbaud, Arnaud Jacquel, Patrick Auberger, Nan Wang, Ross L. Levine, Alan R. Tall, Laurent Yvan-Charvet

Source: Cell Reports, Vol 30, Iss 10, Pp 3397-3410.e5 (2020)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720302242; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/6234ceb8aff4431da1d62fbef1854efd

Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes

Authors: Thomas Cluzeau, Kathy L. McGraw, Brittany Irvine, Erico Masala, Lionel Ades, Ashley A. Basiorka, Jaroslaw Maciejewski, Patrick Auberger, Sheng Wei, Pierre Fenaux, Valeria Santini, Alan List

Source: Haematologica, Vol 102, Iss 12 (2017)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8279; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/2427373ff50e41a9a337710595716baf

Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies

Authors: Guillaume Robert, Arnaud Jacquel, Patrick Auberger

Source: Cells, Vol 8, Iss 10, p 1260 (2019)

Subject Terms: chaperone mediated autophagy, hematological malignancies, lysosome, protein degradation, cma targeting molecules, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/8/10/1260; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/cba21319bf354afa8fada8bc6d121619

Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.

Authors: Patrick Auberger, Philippe Amade, Mohamed Mehiri, Jean Vacelet, Vincent Guérineau, Maeva Dufies, Nathalie Legrave, Souhir Hamrouni-Buonomo

Source: Marine Drugs, Vol 11, Iss 7, Pp 2282-2292 (2013)

Subject Terms: marine natural products, highly oxygenated polyacetylenes, marine sponges, Porifera, Haplosclerida, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.mdpi.com/1660-3397/11/7/2282; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/0f37ead6ef9742358f1171529986444d

A New Hydroxylated Nonaprenylhydroquinone from the Mediterranean Marine Sponge Sarcotragus spinosulus

Authors: Mohamed Mehiri, Guillaume Robert, Vincent Guérineau, Jean Vacelet, Philippe Amade, Patrick Auberger, Maeva Dufies, Charline Abed, Nathalie Legrave

Source: Marine Drugs, Vol 9, Iss 7, Pp 1210-1219 (2011)

Subject Terms: ponges, Sarcotragus spinosulus, marine natural products, hydroxylated polyprenylhydroquinone, bioactivity, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.mdpi.com/1660-3397/9/7/1210/; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/7fd9acc0117a4406a897f521615704d6

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia.

Authors: Mamady Diabate, Patrick Munro, Elsa Garcia, Arnaud Jacquel, Gregory Michel, Sandrine Obba, Diogo Goncalves, Carmelo Luci, Sandrine Marchetti, Dieter Demon, Clara Degos, Yassina Bechah, Jean-Louis Mege, Mohamed Lamkanfi, Patrick Auberger, Jean-Pierre Gorvel, Lynda Maria Stuart, Luce Landraud, Emmanuel Lemichez, Laurent Boyer

Source: PLoS Pathogens, Vol 11, Iss 3, p e1004732 (2015)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/61c90a57fdb742158261c4643d18b7cb

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation

Authors: Frederic Peyrade, Daniel Re, Clemence Ginet, Lauris Gastaud, Maryline Allegra, Robert Ballotti, Antoine Thyss, Thorsten Zenz, Patrick Auberger, Guillaume Robert

Source: Haematologica, Vol 98, Iss 2 (2013)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/6575; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/38a1c03fc9eb4530a7a00eae88a3d0de

Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling.

Authors: Nathalie Belhacéne, Parvati Gamas, Diogo Gonçalvès, Marie Jacquin, Marie Beneteau, Arnaud Jacquel, Pascal Colosetti, Jean-Ehrland Ricci, Abdellilah Wakkach, Patrick Auberger, Sandrine Marchetti

Source: PLoS ONE, Vol 7, Iss 10, p e47321 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23071785/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fb568eaa08fd49bfa4c9ddadfe6c7f54

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy

Authors: Benoist Pruvot, Arnaud Jacquel, Nathalie Droin, Patrick Auberger, Didier Bouscary, Jérome Tamburini, Marc Muller, Michaela Fontenay, Johanna Chluba, Eric Solary

Source: Haematologica, Vol 96, Iss 4 (2011)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/5942; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/9fe3cb130659416bbe993e78da9b66f1

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death.

Authors: Guillaume Robert, Issam Ben Sahra, Alexandre Puissant, Pascal Colosetti, Nathalie Belhacene, Pierre Gounon, Paul Hofman, Fréderic Bost, Jill-Patrice Cassuto, Patrick Auberger

Source: PLoS ONE, Vol 4, Iss 11, p e7889 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19924252/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fdb62ae3eb444b589d2b79bad894e00c