Deep generative AI models analyzing circulating orphan non-coding RNAs enable detection of early-stage lung cancer

Authors: Mehran Karimzadeh, Amir Momen-Roknabadi, Taylor B. Cavazos, Yuqi Fang, Nae-Chyun Chen, Michael Multhaup, Jennifer Yen, Jeremy Ku, Jieyang Wang, Xuan Zhao, Philip Murzynowski, Kathleen Wang, Rose Hanna, Alice Huang, Diana Corti, Dang Nguyen, Ti Lam, Seda Kilinc, Patrick Arensdorf, Kimberly H. Chau, Anna Hartwig, Lisa Fish, Helen Li, Babak Behsaz, Olivier Elemento, James Zou, Fereydoun Hormozdiari, Babak Alipanahi, Hani Goodarzi

Source: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/bfa41ff610b944e99ea17c73581fe401

A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation

Authors: Xiao-Long Cui, Ji Nie, Jeremy Ku, Urszula Dougherty, Diana C. West-Szymanski, Francois Collin, Christopher K. Ellison, Laura Sieh, Yuhong Ning, Zifeng Deng, Carolyn W. T. Zhao, Anna Bergamaschi, Joel Pekow, Jiangbo Wei, Alana V. Beadell, Zhou Zhang, Geeta Sharma, Raman Talwar, Patrick Arensdorf, Jason Karpus, Ajay Goel, Marc Bissonnette, Wei Zhang, Samuel Levy, Chuan He

Source: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/422a834f9ee54a78aa65900aafeb0d8b