Thiopurine 6TG treatment increases tumor immunogenicity and response to immune checkpoint blockade

Authors: Loulieta Nazerai, Shona Caroline Willis, Patricio Yankilevich, Luca Di Leo, Francesca Maria Bosisio, Alex Frias, Corine Bertolotto, Jacob Nersting, Maria Thastrup, Soren Buus, Allan Randrup Thomsen, Morten Nielsen, Kristoffer Staal Rohrberg, Kjeld Schmiegelow, Daniela De Zio

Source: OncoImmunology, Vol 12, Iss 1 (2023)

Subject Terms: Thiopurine, 6TG, immune checkpoint inhibitors, melanoma, mouse model, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/4dfe4b677ec94c7b9323ef328b78f448

Retraction Note: Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy

Authors: María C. Díaz Flaqué, Natalia M. Galigniana, Wendy Béguelin, Rocío Vicario, Cecilia J. Proietti, Rosalía Cordo Russo, Martín A. Rivas, Mercedes Tkach, Pablo Guzmán, Juan C. Roa, Esteban Maronna, Viviana Pineda, Sergio Muñoz, María Florencia Mercogliano, Eduardo H. Charreau, Patricio Yankilevich, Roxana Schillaci, Patricia V. Elizalde

Source: Breast Cancer Research, Vol 25, Iss 1, Pp 1-2 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1465-542X

Access URL: https://doaj.org/article/291557641cce44d291680059236d5d3c

Gene function prediction in five model eukaryotes exclusively based on gene relative location through machine learning

Authors: Flavio Pazos Obregón, Diego Silvera, Pablo Soto, Patricio Yankilevich, Gustavo Guerberoff, Rafael Cantera

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/aa2beb56cd7547488d1f889b69977730

An improved catalogue of putative synaptic genes defined exclusively by temporal transcription profiles through an ensemble machine learning approach

Authors: Flavio Pazos Obregón, Martín Palazzo, Pablo Soto, Gustavo Guerberoff, Patricio Yankilevich, Rafael Cantera

Source: BMC Genomics, Vol 20, Iss 1, Pp 1-8 (2019)

Subject Terms: Synaptic genes, Machine learning, Temporal transcription profiles, Gene function prediction, Drosophila melanogaster, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/7a614cebbe91412a84dee9f1c9f22d52

A pan-cancer somatic mutation embedding using autoencoders

Authors: Martin Palazzo, Pierre Beauseroy, Patricio Yankilevich

Source: BMC Bioinformatics, Vol 20, Iss 1, Pp 1-10 (2019)

Subject Terms: Autoencoder, Kernel learning, Cancer genomics, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/0764c22fc7c14c33a54de37d3fb320b1

miRNome profiling of LSC-enriched CD34+CD38−CD26+ fraction in Ph+ CML-CP samples from Argentinean patients: a potential new pharmacogenomic tool

Authors: María Sol Ruiz, María Belén Sánchez, Simone Bonecker, Carolina Furtado, Daniel Koile, Patricio Yankilevich, Santiago Cranco, María del Rosario Custidiano, Josefina Freitas, Beatriz Moiraghi, Mariel Ana Pérez, Carolina Pavlovsky, Ana Inés Varela, Verónica Ventriglia, Julio César Sánchez Ávalos, Irene Larripa, Ilana Zalcberg, José Mordoh, Peter Valent, Michele Bianchini

Source: Frontiers in Pharmacology, Vol 11 (2021)

Subject Terms: microRNAs, metabolism, leukemic stem cell, leukemia, CD26, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2020.612573/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/6c0cae11e6044816982a5967d272e02b

Evaluation of T-Cell Responses Against Shared Melanoma Associated Antigens and Predicted Neoantigens in Cutaneous Melanoma Patients Treated With the CSF-470 Allogeneic Cell Vaccine Plus BCG and GM-CSF

Authors: Enrique Podaza, Ibel Carri, Mariana Aris, Erika von Euw, Alicia Inés Bravo, Paula Blanco, Juan Manuel Ortiz Wilczyñski, Daniel Koile, Patricio Yankilevich, Morten Nielsen, José Mordoh, María Marcela Barrio

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: cutaneous melanoma, CSF-470 allogeneic cell vaccine, neoantigens, tumor associated antigens, melanoma immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01147/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8566c44582ab4163a12b6169f269e3dc

GenIO: a phenotype-genotype analysis web server for clinical genomics of rare diseases

Authors: Daniel Koile, Marta Cordoba, Maximiliano de Sousa Serro, Marcelo Andres Kauffman, Patricio Yankilevich

Source: BMC Bioinformatics, Vol 19, Iss 1, Pp 1-6 (2018)

Subject Terms: Rare disease, Exome sequencing, Genome sequencing, Clinical informatics, Variant analysis, Bioinformatics, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12859-018-2027-3; https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/2a1dc40835964f878efb83ef83333bbc

Changes in the TCRβ Repertoire and Tumor Immune Signature From a Cutaneous Melanoma Patient Immunized With the CSF-470 Vaccine: A Case Report

Authors: Mariana Aris, Alicia Inés Bravo, María Betina Pampena, Paula Alejandra Blanco, Ibel Carri, Daniel Koile, Patricio Yankilevich, Estrella Mariel Levy, María Marcela Barrio, José Mordoh

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: cutaneous melanoma, CSF-470 vaccine, T-cell receptor β immune repertoire, cancer immunogram, tumor immune infiltration, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2018.00955/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4d1040ed2d6845afb7bb57100dae5ff0

RETRACTED ARTICLE: Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy

Authors: María C Díaz Flaqué, Natalia M Galigniana, Wendy Béguelin, Rocío Vicario, Cecilia J Proietti, Rosalía Cordo Russo, Martín A Rivas, Mercedes Tkach, Pablo Guzmán, Juan C Roa, Esteban Maronna, Viviana Pineda, Sergio Muñoz, María Florencia Mercogliano, Eduardo H Charreau, Patricio Yankilevich, Roxana Schillaci, Patricia V Elizalde

Source: Breast Cancer Research, Vol 15, Iss 6, Pp 1-24 (2013)

Subject Terms: Progesterone Receptor, Progestin, T47D Cell, BT474 Cell, Proximity Ligation Assay, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1465-542X

Access URL: https://doaj.org/article/97467e939197489fb4e4a743f410f448

Asterias: A Parallelized Web-based Suite for the Analysis of Expression and aCGH Data

Authors: Ramón Díaz-Uriarte, Patricio Yankilevich, David Casado, Oscar M. Rueda, Andrés Cañada, Edward R. Morrissey, Andreu Alibés

Source: Cancer Informatics, Vol 3, Pp 1-9 (2007)

Subject Terms: microarray, aCGH, classification, prediction, parallel computing, web-based application, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://la-press.com/article.php?article_id=42; https://doaj.org/toc/1176-9351

Access URL: https://doaj.org/article/323025d0090e4f3a84d786984da5c286

Asterias: A Parallelized Web-based Suite for the Analysis of Expression and aCGH Data

Authors: Andreu Alibés, Edward R. Morrissey, Andrés Cañada, Oscar M. Rueda, David Casado, Patricio Yankilevich, Ramón Díaz-Uriarte

Source: Cancer Informatics, Vol 3 (2007)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1176-9351

Access URL: https://doaj.org/article/e491f83429204672a14fcd8b55daf5e3