TGFβ Inhibition Stimulates Collagen Maturation to Enhance Bone Repair and Fracture Resistance in a Murine Myeloma Model

Authors: Green, Alanna C, Lath, Darren, Hudson, Katie, Walkley, Brant, Down, Jennifer M, Owen, Robert, Evans, Holly R, Paton‐Hough, Julia, Reilly, Gwendolen C, Lawson, Michelle A, Chantry, Andrew D

Source: Journal of bone and mineral research. 34(12):2311-2326

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099962865.0x000001&indx=1&recIds=ETOCvdc_100099962865.0x000001

Preventing and Repairing Myeloma Bone Disease by Combining Conventional Antiresorptive Treatment With a Bone Anabolic Agent in Murine Models

Authors: Paton‐Hough, Julia, Tazzyman, Simon, Evans, Holly, Lath, Darren, Down, Jenny M, Green, Alanna C, Snowden, John A, Chantry, Andrew D, Lawson, Michelle A

Source: Journal of bone and mineral research. 34(5):783-796

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095083490.0x000001&indx=1&recIds=ETOCvdc_100095083490.0x000001

NOD/SCID-GAMMA Mice Are an Ideal Strain to Assess the Efficacy of Therapeutic Agents Used in the Treatment of Myeloma Bone Disease.

Authors: Lawson, Michelle A.^1,2 m.a.lawson@sheffield.ac.uk, Paton-Hough, Julia M.^1,2, Evans, Holly R.^1,2, Walker, Rebecca E.^1,2, Harris, William^1,2, Ratnabalan, Dharshi^1,2, Snowden, John A.^1,3, Chantry, Andrew D.^1,2,3

Source: PLoS ONE. Mar2015, Vol. 10 Issue 3, p1-13. 13p.

Subject Terms: *MULTIPLE myeloma treatment, *ANIMAL models in research, *ANTINEOPLASTIC agents, *LABORATORY mice, *CANCER cells, TREATMENT of bone diseases

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The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-α]Pyridin-3-yl)-Ethyl-Bisphosphonate).

Authors: Lawson, Michelle A, Chantry, Andrew D, Paton-Hough, Julia, Evans, Holly R, Lath, Darren, Tsoumpra, Maria K, Ebetino, Frank H, Russell, R Graham G, Mazur, Adam, Lundy, Mark W, Dobson, Roy LM, Quijano, Michael, Jeans, Gwyn, Kwaasi, Aaron A, Dunford, James E, Duan, Xuchen, Triffitt, James T

Source: Journal of Bone & Mineral Research; Sep2017, Vol. 32 Issue 9, p1860-1869, 10p