PATL2 mutations affect human oocyte maternal mRNA homeostasis and protein interactions in cell cycle regulation

Authors: Yin-Li Zhang, Zhanhong Hu, Huifang Jiang, Jiamin Jin, Yan Zhou, Mengru Lai, Peipei Ren, Siya Liu, Ying-Yi Zhang, Yan Rong, Wei Zheng, Shen Zhang, Xiaomei Tong, Songying Zhang

Source: Cell & Bioscience, Vol 14, Iss 1, Pp 1-22 (2024)

Subject Terms: PATL2 mutation, TUT7, CDC23, mRNA storage, mRNA decay, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/eee8c35daf164d6ebddc6a832f6012e5

Identification of a novel mutation in PATL2 gene associated with the germinal vesicle arrest of oocytes

Authors: Aili Yu, Zhiqing Huang, Hang Shi, Yanying Lin, Xuefen Cai, Zhanghong Ke, Beihong Zheng, Yan Sun

Source: Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101886- (2024)

Subject Terms: Assisted reproductive technology, Oocyte maturation abnormality, Germinal vesicle arrest, PATL2, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405580824002504; https://doaj.org/toc/2405-5808

Access URL: https://doaj.org/article/3c273f6d53504f39bbc70c4b139c1c00

High carrier frequency of pathogenic PATL2 gene mutations predicted in population: a bioinformatics-based approach

Authors: Hao Zhou, Ye-Lan Cai, Qing Luo, Lian Zou, Yong-Xiang Yin, Ying Chen, Fang Xiong

Source: Frontiers in Genetics, Vol 14 (2023)

Subject Terms: infertility, PATL2 mutation, bioinformatic analysis, single nucleotide polymorphism, assisted reproductive technology, germinal vesicle, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2023.1097951/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/4af25d5b7cbc4c2ba5d80d9be7ef522b

Compound heterozygous variation of PATL2 causes oocyte maturation defect

Authors: HUO Ming-zhu, ZHANG Yi-le, XU Jia-wei, SHI Hao, LIU Yi-dong, NIU Wen-bin

Source: Jichu yixue yu linchuang, Vol 42, Iss 1, Pp 51-55 (2022)

Subject Terms: patl2 gene, oocyte maturation defect, Medicine

File Description: electronic resource

Relation: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-51.pdf; https://doaj.org/toc/1001-6325

Access URL: https://doaj.org/article/305837e9e3a043fd839ee3de1fd155fc

Identification and characterization of a novel homozygous splice site variant of PATL2 causing female infertility due to oocyte germinal vesicle arrest

Authors: Liwei Sun, Keya Tong, Weiwei Liu, Yin Tian, Sheng Yang, Danni Zhou, Dongyun Liu, Guoning Huang, Jingyu Li

Source: Frontiers in Genetics, Vol 13 (2022)

Subject Terms: female infertility, germinal vesicle arrest, PATL2, novel variant, aberrant splicing, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2022.967288/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/1395c4fc81024df7835054ec12affb13

The Recurrent Mutation in PATL2 Inhibits Its Degradation Thus Causing Female Infertility Characterized by Oocyte Maturation Defect Through Regulation of the Mos-MAPK Pathway

Authors: Qiqi Cao, Chun Zhao, Congjing Wang, Lingbo Cai, Meng Xia, Xiaolan Zhang, Jian Han, Yangyang Xu, Junqiang Zhang, Xiufeng Ling, Xiang Ma, Ran Huo

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: meiotic maturation, PATL2 mutation, ART, MAPK, female infertility, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.628649/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/7d7942606be842458d2f9721ca147ade

PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice

Authors: Marie Christou‐Kent, Zine‐Eddine Kherraf, Amir Amiri‐Yekta, Emilie Le Blévec, Thomas Karaouzène, Béatrice Conne, Jessica Escoffier, Said Assou, Audrey Guttin, Emeline Lambert, Guillaume Martinez, Magalie Boguenet, Selima Fourati Ben Mustapha, Isabelle Cedrin Durnerin, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Charles Coutton, Nicolas Thierry‐Mieg, Serge Nef, Serge P Bottari, Raoudha Zouari, Jean Paul Issartel, Pierre F Ray, Christophe Arnoult

Source: EMBO Molecular Medicine, Vol 10, Iss 5, Pp 1-24 (2018)

Subject Terms: female sterility, oocyte developmental competence, oocyte maturation arrest, oocyte maturation failure, Patl2, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/2a2704a3d4124064a7b9b19a154a9916

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