Emerging strategies for the prediction of behaviour, growth, and treatment response in vestibular schwannoma.

Authors: Lewis, Daniel, Li, Ka-loh, Djoukhadar, Ibrahim, Hannan, Cathal J., Pathmanaban, Omar N., Coope, David J., King, Andrew T.

Source: Acta Neurochirurgica; 4/22/2025, Vol. 167 Issue 1, p1-11, 11p

Subject Terms: ACOUSTIC neuroma, MEDICAL sciences, TRANSIENTS (Dynamics), PATIENT selection, TREATMENT failure, STEREOTACTIC radiosurgery

Spatial mapping of immune cell environments in NF2-related schwannomatosis vestibular schwannoma.

Authors: Jones, Adam P., Haley, Michael J., Meadows, Miriam H., Gregory, Grace E., Hannan, Cathal J., Simmons, Ana K., Bere, Leoma D., Lewis, Daniel G., Oliveira, Pedro, Smith, Miriam J., King, Andrew T., Evans, D. Gareth R., Paszek, Pawel, Brough, David, Pathmanaban, Omar N., Couper, Kevin N.

Source: Nature Communications; 3/26/2025, Vol. 16 Issue 1, p1-18, 18p

Subject Terms: MYELOID cells, CELL populations, SCHWANN cells, ACOUSTIC neuroma, CYTOMETRY

Translabyrinthine Resection of Collision Tumors and Facial Nerve Reconstruction.

Authors: Drosos, Evangelos¹ (AUTHOR), Pathmanaban, Omar N.¹ (AUTHOR), Hammerbeck-Ward, Charlotte¹ (AUTHOR), King, Andrew T.¹ (AUTHOR), Lloyd, Simon K.² (AUTHOR), Freeman, Simon² (AUTHOR), McClenaghan, Fiona² (AUTHOR), Evans, Gareth D.³ (AUTHOR), Rutherford, Scott¹ (AUTHOR)

Source: Journal of Neurological Surgery. Part B. Skull Base. 2025 Supplement 1, Vol. 86, pS1-S576. 576p.

Subject Terms: *CARCINOSARCOMAS, *ACOUSTIC neuroma, *NERVE grafting, *NEUROFIBROMATOSIS, TUMOR surgery

Multidisciplinary Management of Spheno-Orbital Meningiomas.

Authors: Drosos, Evangelos, Hammerbeck-Ward, Charlotte, King, Andrew T., Pathmanaban, Omar N., Attaulah, Saj, Cannon, Paul S., Laybourne, James, Koutropoulou, Nikolitsa, Wadeson, Andrea, Entwistle, Helen, Rutherford, Scott

Source: Journal of Neurological Surgery. Part B. Skull Base; 2025 Supplement 1, Vol. 86, pS1-S576, 576p

Subject Terms: SURGICAL site infections, EXTERNAL beam radiotherapy, OPHTHALMIC plastic surgery, CAVERNOUS sinus, CEREBROSPINAL fluid leak, DECOMPRESSION (Physiology)

Incidence of mosaicism in 1055 de novo NF2 cases: much higher than previous estimates with high utility of next-generation sequencing

Authors: Evans, D. Gareth, Hartley, Claire L., Smith, Philip T., King, Andrew T., Bowers, Naomi L., Tobi, Simon, Wallace, Andrew J., Perry, Mary, Anup, Raji, Lloyd, Simon K.W., Rutherford, Scott A., Hammerbeck-Ward, Charlotte, Pathmanaban, Omar N., Stapleton, Emma, Freeman, Simon R., Kellett, Mark, Halliday, Dorothy, Parry, Allyson, Gair, Juliette J., Axon, Patrick, Laitt, Roger, Thomas, Owen, Afridi, Shazia K., Obholzer, Rupert, Duff, Chris, Stivaros, Stavros M., Vassallo, Grace, Harkness, Elaine F., Smith, Miriam J.

Source: In Genetics in Medicine January 2020 22(1):53-59

Identifying the deficiencies of current diagnostic criteria for neurofibromatosis 2 using databases of 2777 individuals with molecular testing

Authors: Evans, D. Gareth, King, Andrew T., Bowers, Naomi L., Tobi, Simon, Wallace, Andrew J., Perry, Mary, Anup, Raji, Lloyd, Simon K.L., Rutherford, Scott A., Hammerbeck-Ward, Charlotte, Pathmanaban, Omar N., Stapleton, Emma, Freeman, Simon R., Kellett, Mark, Halliday, Dorothy, Parry, Allyson, Gair, Juliette J., Axon, Patrick, Laitt, Roger, Thomas, Owen, Afridi, Shazia, Ferner, Rosalie E., Harkness, Elaine F., Smith, Miriam J.

Source: In Genetics in Medicine July 2019 21(7):1525-1533

Alternatively activated macrophages are associated with faster growth rate in vestibular schwannoma.

Authors: Gregory, Grace E, Haley, Michael J, Jones, Adam P, Hannan, Cathal J, Evans, D Gareth, King, Andrew T, Paszek, Pawel, Pathmanaban, Omar N, Couper, Kevin N, Brough, David

Source: Brain Communications; 2024, Vol. 6 Issue 6, p1-14, 14p

Genetic findings in people with schwannomas who do not meet clinical diagnostic criteria for NF2-related schwannomatosis.

Authors: Smith, Miriam J., Perez-Becerril, Cristina, van der Meer, Mwee, Burghel, George J., Waller, Sarah J., Carney, Megan, Bunstone, Sancha, Fryer, Katherine, Bowers, Naomi L., Hartley, Claire L., Smith, Philip T., Rutherford, Scott A., Freeman, Simon R., Lloyd, Simon K. W., Pathmanaban, Omar N., King, Andrew Thomas, Halliday, Dorothy, Duff, Chris, Evans, D. Gareth

Source: Journal of Medical Genetics; Nov2024, Vol. 61 Issue 11, p1011-1015, 5p

NF2- related schwannomatosis and other schwannomatosis: an updated genetic and epidemiological study.

Authors: Forde, Claire, Smith, Miriam J., Burghel, George J., Bowers, Naomi, Roberts, Nicola, Lavin, Tim, Halliday, Jane, King, Andrew Thomas, Rutherford, Scott, Pathmanaban, Omar N., Lloyd, Simon, Freeman, Simon, Halliday, Dorothy

Source: Journal of Medical Genetics; Sep2024, Vol. 61 Issue 9, p856-860, 5p

Safety of Superior Petrosal Vein Sacrifice During Microvascular Decompression of the Trigeminal Nerve

Authors: Pathmanaban, Omar. N., O'Brien, Frazer, Al-Tamimi, Yahia Z., Hammerbeck-Ward, Charlotte L., Rutherford, Scott A., King, Andrew T.

Source: In World Neurosurgery July 2017 103:84-87

A watch, wait, and rescan approach for incidental benign-appearing notochordal lesions of the skull base.

Authors: Usher, Inga E., Drosos, Evangelos, Morsy, Abdalla, Wadeson, Andrea, Laitt, Roger, Abdulla, Sarah, Madhavan, Aparna, Halliday, Jane, Rutherford, Scott, King, Andrew T., Pathmanaban, Omar N.

Source: Neurosurgical Focus; May2024, Vol. 56 Issue 5, p1-4, 4p

Venous thromboembolism chemical prophylaxis after skull base surgery.

Authors: Waqar, Mueez, Yaseen, Omar, Chadwick, Annabel, Lee, Jing Xian, Khan, Ghazn, Evans, D. Gareth, Horner, Daniel, Jaiswal, Archana, Freeman, Simon, Bhalla, Rajiv, Lloyd, Simon, Hammerbeck-Ward, Charlotte, Rutherford, Scott A., King, Andrew T., Pathmanaban, Omar N.

Source: Acta Neurochirurgica; 4/3/2024, Vol. 166 Issue 1, p1-10, 10p

Subject Terms: SKULL base, SKULL surgery, THROMBOEMBOLISM, VENOUS thrombosis, PROPENSITY score matching

Low-dose GBCA administration for brain tumour dynamic contrast enhanced MRI: a feasibility study.

Authors: Lewis, Daniel, Li, Ka-Loh, Waqar, Mueez, Coope, David J., Pathmanaban, Omar N., King, Andrew T., Djoukhadar, Ibrahim, Zhao, Sha, Cootes, Timothy F., Jackson, Alan, Zhu, Xiaoping

Source: Scientific Reports; 2/28/2024, Vol. 14 Issue 1, p1-14, 14p

Subject Terms: BRAIN tumors, FEASIBILITY studies, MAGNETIC resonance imaging, KINETIC resolution, CONTRAST media

Evidence for inflammation in normal-appearing brain regions in patients with growing sporadic vestibular schwannoma: A PET study.

Authors: Alfaifi, Bandar, Hinz, Rainer, Jackson, Alan, Wadeson, Andrea, Pathmanaban, Omar N, Hammerbeck-Ward, Charlotte, Rutherford, Scott A, King, Andrew T, Lewis, Daniel, Coope, David J

Source: Neuro-Oncology Advances; Jan-Dec2024, Vol. 6 Issue 1, p1-11, 11p

Does tumoral cavernous carotid stenosis predict an increased risk of future stroke in skull base meningiomas?

Authors: Macarthur, Joshua I., O'Brien, Frazer, Hannan, Cathal John, Hammerbeck-Ward, Charlotte, Pathmanaban, Omar N., Rutherford, Scott A., Siripurapu, Rekha, King, Andrew T., Wayne Ng

Source: Journal of Neurosurgery; Dec2023, Vol. 139 Issue 6, p1613-1618, 6p

Increased neural progenitors in vascular dementia

Authors: Ekonomou, Antigoni, Ballard, Clive G., Pathmanaban, Omar N., Perry, Robert H., Perry, Elaine K., Kalaria, Raj N., Minger, Stephen L.

Source: In Neurobiology of Aging 2011 32(12):2152-2161

Novel Dural-Splitting Operative Technique for Excision of Ventrally Located Spinal Meningiomas

Authors: Okura, Hidehiro, Pathmanaban, Omar N., Munoz, David G., Cusimano, Michael D.

Source: In World Neurosurgery January 2022 157:48-53

Genome-wide association analysis identifies a susceptibility locus for sporadic vestibular schwannoma at 9p21.

Authors: Sadler, Katherine V^1,2, Bowes, John³, Rowlands, Charlie F⁴, Perez-Becerril, Cristina^1,2, Meer, C Mwee van der², King, Andrew T⁵, Rutherford, Scott A⁵, Pathmanaban, Omar N⁵, Hammerbeck-Ward, Charlotte⁵, Lloyd, Simon K W^6,7, Freeman, Simon R⁶, Williams, Ricky⁸, Hannan, Cathal John^5,9, Lewis, Daniel⁵, Eyre, Steve¹⁰, Evans, D Gareth^1,2, Smith, Miriam J^1,2, miriam.smith@manchester.ac.uk

Source: Brain: A Journal of Neurology; Jul2023, Vol. 146 Issue 7, p2861-2868, 8p

The comparable tumour microenvironment in sporadic and NF2-related schwannomatosis vestibular schwannoma.

Authors: Gregory, Grace E., Jones, Adam Paul, Haley, Michael J., Hoyle, Christopher, Zeef, Leo A. H., Lin, I.-Hsuan, Coope, David J., King, Andrew T., Evans, D. Gareth, Paszek, Pawel, Couper, Kevin N., Brough, David, Pathmanaban, Omar N.

Source: Brain Communications; 2023, Vol. 5 Issue 4, p1-15, 15p

The clinical, genetic, and immune landscape of meningioma in patients with NF2-schwannomatosis.

Authors: Gregory, Grace E., Islim, Abdurrahman I., Hannan, Cathal John, Jones, Adam P., Hammerbeck-Ward, Charlotte, Rutherford, Scott A., Freeman, Simon R., Lloyd, Simon, Kalamarides, Michel, Smith, Miriam J., Couper, Kevin, McBain, Catherine A., Jenkinson, Michael D., Brough, David, King, Andrew T., Evans, D. Gareth, Pathmanaban, Omar N.

Source: Neuro-Oncology Advances; 2023 Supplement, Vol. 5, pi94-i104, 11p