Airway extracellular LTA4H concentrations are governed by release from liver hepatocytes and changes in lung vascular permeability

Authors: Mincham, Kyle T. ¹, Akthar, Samia ¹, Patel, Dhiren F. ^{1, 2}, Meyer, Garance F. ¹, Lloyd, Clare M. ¹, Gaggar, Amit ^{3, 4, 5, 6}, Blalock, James E. ^{3, 4, 5}, Snelgrove, Robert J. ^{1, 7, ∗}

Source: In Cell Reports 27 August 2024 43(8)

Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis

Authors: Turnbull, Andrew R., Pyle, Chloe J., Patel, Dhiren F., Jackson, Patricia L., Hilliard, Tom N., Regamey, Nicolas, Tan, Hui-Leng, Brown, Sarah, Thursfield, Rebecca, Short, Christopher, Mc Fie, Megan, Alton, Eric W.F.W., Gaggar, Amit, Blalock, J. Edwin, Lloyd, Clare M., Bush, Andrew, Davies, Jane C., Snelgrove, Robert J.

Source: In Journal of Cystic Fibrosis January 2020 19(1):40-48

Matrix Metalloproteinase-12 Supports Pulmonary B Cell Follicle Formation and Local Antibody Responses During Asthma.

Authors: Pyle, Chloe J., Patel, Dhiren F., Peir, Teresa, Joulia, Regis, Grabiec, Aleksander M., Hussell, Tracy

Source: American Journal of Respiratory & Critical Care Medicine; 12/1/2022, Vol. 206 Issue 11, p1424-1428, 5p

Zooming into the Matrix: Using Nonlinear Optical Microscopy to Visualize Collagen Remodeling in Asthmatic Airways

Authors: Snelgrove, Robert J., Patel, Dhiren F.

Source: American journal of respiratory and critical care medicine. 200(4):403-404

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621130820&indx=1&recIds=ETOCRN621130820

Differential Regulation of Allergic Airway Inflammation by Acetylcholine.

Authors: Roberts, Luke B., Berkachy, Rita, Wane, Madina, Patel, Dhiren F., Schnoeller, Corinna, Lord, Graham M., Gounaris, Kleoniki, Ryffel, Bernhard, Quesniaux, Valerie, Darby, Matthew, Horsnell, William G. C., Selkirk, Murray E.

Source: Frontiers in Immunology; 5/27/2022, Vol. 13, p1-13, 13p

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Response to Comment on "An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness".

Authors: Patel, Dhiren F., Gaggar, Amit, Blalock, J. Edwin, Gregory, Lisa G., Lloyd, Clare M., Snelgrove, Robert J.

Source: Science Translational Medicine; 6/19/2019, Vol. 11 Issue 497, p1-4, 4p

Subject Terms: EXTRACELLULAR matrix, EVIDENCE

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Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection.

Authors: Peiró, Teresa, Patel, Dhiren F., Akthar, Samia, Gregory, Lisa G., Pyle, Chloe J., Harker, James A., Birrell, Mark A., Lloyd, Clare M., Snelgrove, Robert J.

Source: Thorax; Jun2018, Vol. 73 Issue 6, p546-556, 11p, 5 Graphs

Subject Terms: NEUTROPHILS, RESPIRATORY infections, RESPIRATORY diseases, MACROPHAGES, VIRUS diseases, ANIMAL experimentation, COMPARATIVE studies, INTERLEUKIN-1, RESEARCH methodology, MEDICAL cooperation, MICE, PROTEINS, RESEARCH, RESEARCH funding, EVALUATION research

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The development of novel LTA4H modulators to selectively target LTB4 generation.

Authors: Low, Caroline M., Akthar, Samia, Patel, Dhiren F., Löser, Stephan, Wong, Chi-Tung, Jackson, Patricia L., Blalock, J. Edwin, Hare, Stephen A., Lloyd, Clare M., Snelgrove, Robert J.

Source: Scientific Reports; 3/17/2017, p44449, 1p