Influence of Maceration Solvent on Chemical Composition of Gemmotherapy Macerates—A Case Study on Olea europaea Young Shoots

Authors: Dimitri Bréard, Hélène Esselin, Lucie Bugeia, Séverine Boisard, David Guilet, Pascal Richomme, Anne-Marie Le Ray, Christophe Ripoll

Source: Nutraceuticals, Vol 3, Iss 4, Pp 574-590 (2023)

Subject Terms: gemmotherapy, bud, Olea europaea, phytochemical analysis, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://www.mdpi.com/1661-3821/3/4/41; https://doaj.org/toc/1661-3821

Access URL: https://doaj.org/article/4e679ac0080048fe9f82e602fd6ebbc5

Implementation of a MS/MS database for isoquinoline alkaloids and other annonaceous metabolites

Authors: Salemon Akpa Agnès, Timothée Okpekon, Yvette Affoué Kouadio, Adrien Jagora, Dimitri Bréard, Emmanoel V. Costa, Felipe M. A. da Silva, Hector H. F. Koolen, Anne-Marie Le Ray-Richomme, Pascal Richomme, Pierre Champy, Mehdi A. Beniddir, Pierre Le Pogam

Source: Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2052-4463

Access URL: https://doaj.org/article/9fbfc2ffadcf4c189937bd256058039a

Oxostephanine, Thalmiculine, and Thaliphyline—Three Isoquinoleine Alkaloids That Inhibit L-Type Voltage-Gated Ca2+ Channels

Authors: Jacinthe Frangieh, Claire Legendre, Dimitri Bréard, Pascal Richomme, Daniel Henrion, Ziad Fajloun, César Mattei, Anne-Marie Le Ray, Christian Legros

Source: Future Pharmacology, Vol 2, Iss 3, Pp 238-255 (2022)

Subject Terms: isoquinoline alkaloids, L-type voltage-gated Ca2+ channels, intracellular Ca2+ measurement, Fura-2 fluorescent probe, GH3b6 cells, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2673-9879/2/3/16; https://doaj.org/toc/2673-9879

Access URL: https://doaj.org/article/43c57006fac940fa92c0ad04aeb47dbd

Screening an In-House Isoquinoline Alkaloids Library for New Blockers of Voltage-Gated Na+ Channels Using Voltage Sensor Fluorescent Probes: Hits and Biases

Authors: Quentin Coquerel, Claire Legendre, Jacinthe Frangieh, Stephan De Waard, Jérôme Montnach, Leos Cmarko, Joseph Khoury, Charifat Said Hassane, Dimitri Bréard, Benjamin Siegler, Ziad Fajloun, Harold De Pomyers, Kamel Mabrouk, Norbert Weiss, Daniel Henrion, Pascal Richomme, César Mattei, Michel De Waard, Anne-Marie Le Ray, Christian Legros

Source: Molecules, Vol 27, Iss 13, p 4133 (2022)

Subject Terms: voltage-gated sodium channel, isoquinoline alkaloids, oxoaporphine, voltage sensor probes, Na+ fluorescent probe ANG-2, GH3b6 cells, Organic chemistry, QD241-441

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Relation: https://www.mdpi.com/1420-3049/27/13/4133; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/3c3824003c5c472796fb3122b1c94452

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase

Authors: Helmut Pein, Alexia Ville, Simona Pace, Veronika Temml, Ulrike Garscha, Martin Raasch, Khaled Alsabil, Guillaume Viault, Chau-Phi Dinh, David Guilet, Fabiana Troisi, Konstantin Neukirch, Stefanie König, Rosella Bilancia, Birgit Waltenberger, Hermann Stuppner, Maria Wallert, Stefan Lorkowski, Christina Weinigel, Silke Rummler, Marc Birringer, Fiorentina Roviezzo, Lidia Sautebin, Jean-Jacques Helesbeux, Denis Séraphin, Alexander S. Mosig, Daniela Schuster, Antonietta Rossi, Pascal Richomme, Oliver Werz, Andreas Koeberle

Source: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8f5b1e43017943509f14b4b68fe07ec5

A Descriptive Chemical Composition of Concentrated Bud Macerates through an Optimized SPE-HPLC-UV-MS2 Method—Application to Alnus glutinosa, Ribes nigrum, Rosa canina, Rosmarinus officinalis and Tilia tomentosa

Authors: Thomas Charpentier, Séverine Boisard, Anne-Marie Le Ray, Dimitri Bréard, Amélie Chabrier, Hélène Esselin, David Guilet, Christophe Ripoll, Pascal Richomme

Source: Plants, Vol 11, Iss 2, p 144 (2022)

Subject Terms: concentrated bud macerates, HPLC-UV-MS, flavonoid content, antioxidant activity, Botany, QK1-989

File Description: electronic resource

Relation: https://www.mdpi.com/2223-7747/11/2/144; https://doaj.org/toc/2223-7747

Access URL: https://doaj.org/article/e15927b05c11444393f87f6d46e69068

Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3

Authors: Gabriele Möller, Veronika Temml, Antonio Cala Peralta, Océane Gruet, Pascal Richomme, Denis Séraphin, Guillaume Viault, Luisa Kraus, Petra Huber-Cantonati, Elisabeth Schopfhauser, Johanna Pachmayr, Janina Tokarz, Daniela Schuster, Jean-Jacques Helesbeux, Kenneth Allen Dyar

Source: Metabolites, Vol 12, Iss 2, p 99 (2022)

Subject Terms: chalcone, aldo-keto reductase, cancer, AKR1C3, 17β-hydroxysteroid dehydrogenase, 3α-hydroxysteroid dehydrogenase, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/12/2/99; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/2ab68851bb2c41d1830b279e836dcadf

Behavioral and Antennal Responses of Tribolium confusum to Varronia globosa Essential Oil and Its Main Constituents: Perspective for Their Use as Repellent

Authors: Cesar Auguste Badji, Jean Dorland, Lynda Kheloul, Dimitri Bréard, Pascal Richomme, Abdellah Kellouche, Claudio Roberto Azevedo de Souza, Antônio Lourenço Bezerra, Sylvia Anton

Source: Molecules, Vol 26, Iss 15, p 4393 (2021)

Subject Terms: stored insect pest, caatinga plant, olfactometry, electroantennogram, alternative pest control, essential oil, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/15/4393; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/97593fe07a944ff9bf1b2afb58f8336b

Identification and Quantification of a Phytotoxic Metabolite from Alternaria dauci

Authors: Martha Leyte-Lugo, Pascal Richomme, Pascal Poupard, Luis M. Peña-Rodriguez

Source: Molecules, Vol 25, Iss 17, p 4003 (2020)

Subject Terms: phytotoxins, Alternaria leaf blight, Daucus carota, p-hydroxybenzoic acid, α-acetylorcinol, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/17/4003; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/2a95b70250b8411e8d9bbadbcdf77152

Targeting MHC Regulation Using Polycyclic Polyprenylated Acylphloroglucinols Isolated from Garcinia bancana

Authors: Chloé Coste, Nathalie Gérard, Chau Phi Dinh, Antoine Bruguière, Caroline Rouger, Sow Tein Leong, Khalijah Awang, Pascal Richomme, Séverine Derbré, Béatrice Charreau

Source: Biomolecules, Vol 10, Iss 9, p 1266 (2020)

Subject Terms: endothelium, Clusiaceae, Garcinia bancana, guttiferone F, guttiferone J, major histocompatibility complex, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/10/9/1266; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/7c0e07486d374a92b245df481ad81dbf

Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters

Authors: Jérémie Babonneau, Dimitri Bréard, Marie-Line Reynaert, Estelle Marion, David Guilet, Jean-Paul Saint André, Anne Croué, Priscille Brodin, Pascal Richomme, Laurent Marsollier

Source: Frontiers in Pharmacology, Vol 10 (2019)

Subject Terms: Mycobacterium ulcerans, mycolactone, analgesia, bioavailability, biological action, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00378/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/6b1ea27f92414b5a88533395166bdb01

Aldaulactone – An Original Phytotoxic Secondary Metabolite Involved in the Aggressiveness of Alternaria dauci on Carrot

Authors: Julia Courtial, Latifa Hamama, Jean-Jacques Helesbeux, Mickaël Lecomte, Yann Renaux, Esteban Guichard, Linda Voisine, Claire Yovanopoulos, Bruno Hamon, Laurent Ogé, Pascal Richomme, Mathilde Briard, Tristan Boureau, Séverine Gagné, Pascal Poupard, Romain Berruyer

Source: Frontiers in Plant Science, Vol 9 (2018)

Subject Terms: Alternaria leaf blight, aggressiveness, fungal pathogenicity, in vitro culture, phytotoxin, quantitative disease resistance, Plant culture, SB1-1110

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fpls.2018.00502/full; https://doaj.org/toc/1664-462X

Access URL: https://doaj.org/article/a989e3dc681543daa5384270e2a1f9e0

Identification of Minor Benzoylated 4-Phenylcoumarins from a Mammea neurophylla Bark Extract

Authors: Bach Tai Dang, Caroline Rouger, Marc Litaudon, Pascal Richomme, Denis Séraphin, Séverine Derbré

Source: Molecules, Vol 20, Iss 10, Pp 17735-17746 (2015)

Subject Terms: 4-(1-acetoxypropyl)coumarins, benzoylcoumarins, Calophyllaceae, dereplication analysis, 4-phenylcoumarins, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/20/10/17735; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/126032d2fc7c47cb932d7dea2fd5d926

Monitoring the Secretory Behavior of the Rat Adrenal Medulla by High-Performance Liquid Chromatography-Based Catecholamine Assay from Slice Supernatants

Authors: Frédéric De Nardi, Claudie Lefort, Dimitri Bréard, Pascal Richomme, Christian Legros, Nathalie C. Guérineau

Source: Frontiers in Endocrinology, Vol 8 (2017)

Subject Terms: high-performance liquid chromatography, catecholamine release, fluorescence derivatization, stimulus-secretion coupling, acute adrenal slice, medullary tissue, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

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Relation: http://journal.frontiersin.org/article/10.3389/fendo.2017.00248/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/2fbc5a2ff17d443fbc013e4ad542648f

Absolute Configuration of Mycosporine-Like Amino Acids, Their Wound Healing Properties and In Vitro Anti-Aging Effects

Authors: Maria Orfanoudaki, Anja Hartmann, Mostafa Alilou, Thomas Gelbrich, Patricia Planchenault, Séverine Derbré, Andreas Schinkovitz, Pascal Richomme, Andreas Hensel, Markus Ganzera

Source: Marine Drugs, Vol 18, Iss 1, p 35 (2019)

Subject Terms: mycosporine-like amino acids, stereochemistry, x-ray crystallography, ecd, anti-aging, wound healing, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1660-3397/18/1/35; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/a6cee07b5a19446ab2abe254cf14e696

Tuning a 96-Well Microtiter Plate Fluorescence-Based Assay to Identify AGE Inhibitors in Crude Plant Extracts

Authors: Luc Séro, Lionel Sanguinet, Patricia Blanchard, Bach Tai Dang, Sylvie Morel, Pascal Richomme, Denis Séraphin, Séverine Derbré

Source: Molecules, Vol 18, Iss 11, Pp 14320-14339 (2013)

Subject Terms: advanced glycation end-products, automation, fluorescence, natural products, pentosidine, plant extract screening, vesperlysines, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/18/11/14320; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/24c63052d3da4bed9534b7dc2901bd3c

Comparison of Two Methods, UHPLC-UV and UHPLC-MS/MS, for the Quantification of Polyphenols in Cider Apple Juices

Authors: Ingrid Freuze, Pascal Richomme, François Laurens, David Guilet, Cindy F. Verdu, Julia Gatto

Source: Molecules, Vol 18, Iss 9, Pp 10213-10227 (2013)

Subject Terms: Malus x domestica, LC-UV, LC-MSn, phenolic compounds, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/18/9/10213; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/f2b1a64612414517859938c850ecbe11

Triazolobithiophene Light Absorbing Self-Assembled Monolayers: Synthesis and Mass Spectrometry Applications

Authors: Denis Séraphin, Pascal Richomme, Eric Levillain, Jean-Jacques Helesbeux, Marylène Dias, Séverine Derbré, Kamal Elouarzaki, Suresh Babu, Andreas Schinkovitz, Ghislain Tsague Kenfack

Source: Molecules, Vol 16, Iss 10, Pp 8758-8774 (2011)

Subject Terms: light absorbing SAMs, DIAMS MS, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/16/10/8758/; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/037364cc2e7643b59301a6d956f69215

Isoquinolines from the Roots of Thalictrum flavum L. and Their Evaluation as Antiparasitic Compounds

Authors: Pascal Richomme, Jacqueline Ropivia, Fabrice Pagniez, Patrice Le Pape, Séverine Derbré, Caroline Rouger

Source: Molecules, Vol 15, Iss 9, Pp 6476-6484 (2010)

Subject Terms: Antiparasitic, bisbenzylisoquinolines, isoquinoline alkaloids, Ranunculaceae, Thalictrum flavum, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/15/9/6476/; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/0f913c7ee20241e88ef24f9746a2bf73

Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells.

Authors: Caroline Rouger, Sylvain Pagie, Séverine Derbré, Anne-Marie Le Ray, Pascal Richomme, Béatrice Charreau

Source: PLoS ONE, Vol 11, Iss 12, p e0167361 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5131938?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a654bafce3fa48e9a9805063bd31b94d