Synthesis and biological evaluation of a new class of azole urea compounds as Akt inhibitors with promising anticancer activity in pancreatic cancer models

Authors: Pecoraro, Camilla ^a, Scianò, Fabio ^{a, b}, Carbone, Daniela ^a, Xu, Geng ^b, Deng, Juan ^b, Cascioferro, Stella ^{a, ⁎}, Giovannetti, Elisa ^{b, c, ⁎}, Diana, Patrizia ^a, Parrino, Barbara ^a

Source: In Bioorganic Chemistry December 2024 153

Triazole derivatives inhibit the VOR complex-mediated nuclear transport of extracellular particles: Potential application in cancer and HIV-1 infection

Authors: Carbone, Daniela, Santos, Mark F., Corbeil, Denis, Vistoli, Giulio, Parrino, Barbara, Karbanová, Jana, Cascioferro, Stella, Pecoraro, Camilla, Bauson, Jodi, Eliwat, Waleed, Aalam, Feryal, Cirrincione, Girolamo, Lorico, Aurelio, Diana, Patrizia

Source: In Bioorganic Chemistry September 2024 150

Multi or Single-Kinase Inhibitors to Counteract Drug Resistance in Cancer: What is New?

Authors: Pecoraro, Camilla, Carbone, Daniela, Cascioferro, Stella Maria, Parrino, Barbara, Diana, Patrizia

Source: Current medicinal chemistry. 30(7):776-782

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171042334.0x000001&indx=1&recIds=ETOCvdc_100171042334.0x000001

1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation

Authors: Pecoraro, Camilla ^{a, 1}, De Franco, Michele ^{b, 1}, Carbone, Daniela ^a, Bassani, Davide ^c, Pavan, Matteo ^c, Cascioferro, Stella ^a, Parrino, Barbara ^a, Cirrincione, Girolamo ^a, Dall’Acqua, Stefano ^b, Moro, Stefano ^c, Gandin, Valentina ^{b, ∗∗}, Diana, Patrizia ^{a, ∗}

Source: In European Journal of Medicinal Chemistry 5 March 2023 249

Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification

Authors: Carbone, Daniela, Vestuto, Vincenzo, Ferraro, Maria Rosalia, Ciaglia, Tania, Pecoraro, Camilla, Sommella, Eduardo, Cascioferro, Stella, Salviati, Emanuela, Novi, Sara, Tecce, Mario Felice, Amodio, Giuseppina, Iraci, Nunzio, Cirrincione, Girolamo, Campiglia, Pietro, Diana, Patrizia, Bertamino, Alessia, Parrino, Barbara, Ostacolo, Carmine

Source: In European Journal of Medicinal Chemistry 15 April 2022 234

CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin

Authors: Di Franco, Simone, Parrino, Barbara, Gaggianesi, Miriam, Pantina, Vincenzo Davide, Bianca, Paola, Nicotra, Annalisa, Mangiapane, Laura Rosa, Lo Iacono, Melania, Ganduscio, Gloria, Veschi, Veronica, Brancato, Ornella Roberta, Glaviano, Antonino, Turdo, Alice, Pillitteri, Irene, Colarossi, Lorenzo, Cascioferro, Stella, Carbone, Daniela, Pecoraro, Camilla, Fiori, Micol Eleonora, De Maria, Ruggero, Todaro, Matilde, Screpanti, Isabella, Cirrincione, Girolamo, Diana, Patrizia, Stassi, Giorgio

Source: In iScience 25 June 2021 24(6)

1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A

Authors: Parrino, Barbara, Carbone, Daniela, Cascioferro, Stella, Pecoraro, Camilla, Giovannetti, Elisa, Deng, Dongmei, Di Sarno, Veronica, Musella, Simona, Auriemma, Giulia, Cusimano, Maria Grazia, Schillaci, Domenico, Cirrincione, Girolamo, Diana, Patrizia

Source: In European Journal of Medicinal Chemistry 1 January 2021 209

1, 2, 4‐Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase

Authors: Carbone, Daniela, Parrino, Barbara, Cascioferro, Stella, Pecoraro, Camilla, Giovannetti, Elisa, Di Sarno, Veronica, Musella, Simona, Auriemma, Giulia, Cirrincione, Girolamo, Diana, Patrizia

Source: ChemMedChem. 16(3):537-554

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114351255.0x000001&indx=1&recIds=ETOCvdc_100114351255.0x000001

Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm‐Associated Infections

Authors: Cascioferro, Stella, Carbone, Daniela, Parrino, Barbara, Pecoraro, Camilla, Giovannetti, Elisa, Cirrincione, Girolamo, Diana, Patrizia

Source: ChemMedChem. 16(1):65-80

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114578871.0x000001&indx=1&recIds=ETOCvdc_100114578871.0x000001

Exploring the therapeutic potential of a novel series of imidazothiadiazoles targeting focal adhesion kinase (FAK) for pancreatic cancer treatment: synthesis, mechanistic insights and promising antitumor and safety profile.

Authors: Pecoraro, Camilla, Carbone, Daniela, Scianò, Fabio, Terrana, Francesca, Xu, Geng, Bergonzini, Cecilia, Roeten, Margot S. F., Cascioferro, Stella, Cirrincione, Girolamo, Diana, Patrizia, Giovannetti, Elisa, Parrino, Barbara

Source: Journal of Drug Targeting; Dec2024, Vol. 32 Issue 10, p1278-1294, 17p

Subject Terms: FOCAL adhesion kinase, PROTEIN-tyrosine kinases, PANCREATIC duct, CELL adhesion, KINASES

1, 2, 4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation

Authors: Pecoraro, Camilla, De Franco, Michele, Carbone, Daniela, Bassani, Davide, Pavan, Matteo, Cascioferro, Stella, Parrino, Barbara, Cirrincione, Girolamo, Dall'Acqua, Stefano, Moro, Stefano, Gandin, Valentina, Diana, Patrizia

Source: European journal of medicinal chemistry. 249

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183345792.0x000001&indx=1&recIds=ETOCvdc_100183345792.0x000001

Corrigendum to “Synthesis and biological evaluation of a new class of azole urea compounds as Akt inhibitors with promising anticancer activity in pancreatic cancer models” [Bioorg. Chem. 153 (2024) 107959]

Authors: Pecoraro, Camilla ^a, Scianò, Fabio ^{a, b}, Carbone, Daniela ^a, Xu, Geng ^b, Deng, Juan ^b, Cascioferro, Stella ^{a, ⁎}, Giovannetti, Elisa ^{b, c, ⁎}, Diana, Patrizia ^a, Parrino, Barbara ^a

Source: In Bioorganic Chemistry January 2025 154

Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells

Authors: Cascioferro, Stella, Petri, Giovanna Li, Parrino, Barbara, Carbone, Daniela, Funel, Niccola, Bergonzini, Cecilia, Mantini, Giulia, Dekker, Henk, Geerke, Daan, Peters, Godefridus J., Cirrincione, Girolamo, Giovannetti, Elisa, Diana, Patrizia

Source: In European Journal of Medicinal Chemistry 1 March 2020 189

Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation

Authors: Salviati, Emanuela, Ciaglia, Elena, Sommella, Eduardo, Montella, Francesco, Bertamino, Alessia, Ostacolo, Carmine, Parrino, Barbara, Rubino, Roberta, Vecchione, Carmine, Puca, Annibale, Novellino, Ettore, Campiglia, Pietro

Source: In Journal of Functional Foods October 2019 61

2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors

Authors: Cascioferro, Stella, Parrino, Barbara, Petri, Giovanna Li, Cusimano, Maria Grazia, Schillaci, Domenico, Di Sarno, Veronica, Musella, Simona, Giovannetti, Elisa, Cirrincione, Girolamo, Diana, Patrizia

Source: In European Journal of Medicinal Chemistry 1 April 2019 167:200-210

Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines

Authors: Frasson, Ilaria, Spanò, Virginia, Di Martino, Simona, Nadai, Matteo, Doria, Filippo, Parrino, Barbara, Carbone, Anna, Cascioferro, Stella Maria, Diana, Patrizia, Cirrincione, Girolamo, Freccero, Mauro, Barraja, Paola, Richter, Sara N., Montalbano, Alessandra

Source: In European Journal of Medicinal Chemistry 15 January 2019 162:176-193

Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance

Authors: Parrino, Barbara, Schillaci, Domenico, Carnevale, Ilaria, Giovannetti, Elisa, Diana, Patrizia, Cirrincione, Girolamo, Cascioferro, Stella

Source: In European Journal of Medicinal Chemistry 1 January 2019 161:154-178

Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity

Authors: Parrino, Barbara, Ullo, Salviana, Attanzio, Alessandro, Cascioferro, Stella, Spanò, Virginia, Carbone, Anna, Montalbano, Alessandra, Barraja, Paola, Cirrincione, Girolamo, Tesoriere, Luisa, Diana, Patrizia

Source: In European Journal of Medicinal Chemistry 5 October 2018 158:236-246

Novel strategies in the war against antibiotic resistance

Authors: Cascioferro, Stella, Parrino, Barbara, Carbone, Daniela, Pecoraro, Camilla, Diana, Patrizia

Source: Future medicinal chemistry. 13(6):529-531

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187373255.0x000001&indx=1&recIds=ETOCvdc_100187373255.0x000001

Synthesis and photocytotoxic activity of [1, 2, 3]triazolo[4, 5-h][1, 6]naphthyridines and [1, 3]oxazolo[5, 4-h][1, 6]naphthyridines

Authors: Frasson, Ilaria, Spanò, Virginia, Di Martino, Simona, Nadai, Matteo, Doria, Filippo, Parrino, Barbara, Carbone, Anna, Cascioferro, Stella Maria, Diana, Patrizia, Cirrincione, Girolamo, Freccero, Mauro, Barraja, Paola, Richter, Sara N., Montalbano, Alessandra

Source: European journal of medicinal chemistry. 162:176-193

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100119226119.0x000001&indx=1&recIds=ETOCvdc_100119226119.0x000001