Development and Validation of a Deep-Learning Model for Differential Treatment Benefit Prediction for Adults with Major Depressive Disorder Deployed in the Artificial Intelligence in Depression Medication Enhancement (AIDME) Study

Authors: Benrimoh, David, Armstrong, Caitrin, Mehltretter, Joseph, Fratila, Robert, Perlman, Kelly, Israel, Sonia, Kapelner, Adam, Parikh, Sagar V., Karp, Jordan F., Heller, Katherine, Turecki, Gustavo

Subject Terms: Quantitative Biology - Neurons and Cognition, Computer Science - Machine Learning

Access URL: http://arxiv.org/abs/2406.04993

Change in neurocognitive functioning in patients with treatment-resistant depression with serial intravenous ketamine infusions: The Bio-K multicenter trial

Authors: Singh, Balwinder, Parikh, Sagar V., Voort, Jennifer L. Vande, Pazdernik, Vanessa K., Achtyes, Eric D., Goes, Fernando S., Yocum, Anastasia K., Nykamp, Louis, Becerra, Alexis, Smart, LeAnn, Greden, John F., Bobo, William V., Frye, Mark A., Burdick, Katherine E., Ryan, Kelly A.

Source: In Psychiatry Research May 2024 335

Clinical outcomes in the biomarkers of ketamine (Bio-K) study of open-label IV ketamine for refractory depression

Authors: Parikh, Sagar V., Vande Voort, Jennifer L., Yocum, Anastasia K., Achtyes, Eric, Goes, Fernando S., Nykamp, Louis, Singh, Balwinder, Lopez-Vives, Daniela, Sera, Cortney E., Maixner, Daniel, Tarnal, Vijay, Severe, Jennifer, Bartek, Steven, Tye, Susannah J., Rico, Jose, Stoppel, Cynthia J., Becerra, Alexis, Smart, LeAnn, Miller, Christina R., Frye, Mark A., Greden, John F., Bobo, William V.

Source: In Journal of Affective Disorders 1 March 2024 348:143-151

ABCB1 Gene Variants and Antidepressant Treatment Outcomes: A Systematic Review and Meta‐Analysis Including Results from the CAN‐BIND‐1 Study

Authors: Magarbeh, Leen, Hassel, Claudia, Choi, Maximilian, Islam, Farhana, Marshe, Victoria S., Zai, Clement C., Zuberi, Rayyan, Gammal, Roseann S., Men, Xiaoyu, Scherf‐Clavel, Maike, Enko, Dietmar, Frey, Benicio N., Milev, Roumen, Soares, Claudio N., Parikh, Sagar V., Placenza, Franca, Strother, Stephen C., Hassel, Stefanie, Taylor, Valerie H., Leri, Francesco, Blier, Pierre, Farzan, Faranak, Lam, Raymond W., Turecki, Gustavo, Foster, Jane A., Rotzinger, Susan, Kloiber, Stefan, Kennedy, James L., Kennedy, Sidney H., Bousman, Chad A., Müller, Daniel J.

Source: Clinical pharmacology & therapeutics. 114(1):88-117

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195125619.0x000001&indx=1&recIds=ETOCvdc_100195125619.0x000001

The Differential Relation of Emotional, Physical, and Sexual Abuse Histories to Antidepressant Treament Remission and Persistence of Anhedonia in Major Depression: A CAN-BIND-I Report

Authors: Harkness, Kate L., Chakrabarty, Trisha, Rizvi, Sakina J., Mazurka, Raegan, Quilty, Lena, Uher, Rudolf, Milev, Roumen V., Frey, Benicio N., Parikh, Sagar V., Foster, Jane A.

Source: Canadian journal of psychiatry. 68(8):586-595

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633424822&indx=1&recIds=ETOCRN633424822

Patients' recovery and non-recovery narratives after intravenous ketamine for treatment-resistant depression

Authors: Lapidos, Adrienne, Lopez-Vives, Daniela, Sera, Cortney E., Ahearn, Elizabeth, Vest, Erica, Senic, Ivana, Vande Voort, Jennifer L., Frye, Mark, Goes, Fernando S., Achtyes, Eric, Greden, John, Parikh, Sagar V.

Source: Journal of affective disorders. 323:534-539

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190948936.0x000001&indx=1&recIds=ETOCvdc_100190948936.0x000001

The Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Report: Serotonergic Psychedelic Treatments for Major Depressive Disorder

Authors: Rosenblat, Joshua D., Husain, M. Ishrat, Lee, Yena, McIntyre, Roger S., Mansur, Rodrigo B., Castle, David, Offman, Hilary, Parikh, Sagar V., Frey, Benicio N., Schaffer, Ayal

Source: Canadian journal of psychiatry. 68(1):5-21

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630906532&indx=1&recIds=ETOCRN630906532

A mixed-methods feasibility study of a novel AI-enabled, web-based, clinical decision support system for the treatment of major depression in adults

Authors: Qassim, Sabrina, Golden, Grace, Slowey, Dominique, Sarfas, Mary, Whitmore, Kate, Perez, Tamara, Strong, Elizabeth, Lundrigan, Eryn, Fradette, Marie-Jeanne, Baxter, Jacob, Desormeau, Bennet, Tanguay-Sela, Myriam, Popescu, Christina, Israel, Sonia, Perlman, Kelly, Armstrong, Caitrin, Fratila, Robert, Mehltretter, Joseph, Looper, Karl, Steiner, Warren, Rej, Soham, Karp, Jordan F., Heller, Katherine, Parikh, Sagar V., McGuire-Snieckus, Rebecca, Ferrari, Manuela, Margolese, Howard, Benrimoh, David

Source: In Journal of Affective Disorders Reports December 2023 14

The course of insomnia symptoms during the acute treatment of major depressive disorder: A CAN-BIND-1 report

Authors: Dama, Manish, Wu, Michelle, Tassone, Vanessa K., Demchenko, Ilya, Frey, Benicio N., Milev, Roumen V., Ravindran, Arun V., Parikh, Sagar V., Rotzinger, Susan, Lou, Wendy, Lam, Raymond W., Kennedy, Sidney H., Bhat, Venkat

Source: In Psychiatry Research July 2023 325

Response Inhibition and Predicting Response to Pharmacological and Cognitive Behavioral Therapy Treatments for Major Depressive Disorder: A Canadian Biomarker Integration Network for Depression Study

Authors: Dhami, Prabhjot, Quilty, Lena C., Schwartzmann, Benjamin, Uher, Rudolf, Allen, Timothy A., Kloiber, Stefan, Lam, Raymond W., MacQueen, Glenda, Frey, Benicio N., Milev, Roumen, Müller, Daniel J., Strother, Stephen C., Blier, Pierre, Soares, Claudio N., Parikh, Sagar V., Turecki, Gustavo, Foster, Jane A., Rotzinger, Susan, Kennedy, Sidney H., Farzan, Faranak

Source: In Biological Psychiatry: Cognitive Neuroscience and Neuroimaging February 2023 8(2):162-170

Clinical and demographic factors associated with delayed diagnosis of bipolar disorder: Data from Health Outcomes and Patient Evaluations in Bipolar Disorder (HOPE-BD) study

Authors: Keramatian, Kamyar, Pinto, Jairo V, Schaffer, Ayal, Sharma, Verinder, Beaulieu, Serge, Parikh, Sagar V, Yatham, Lakshmi N

Source: Journal of affective disorders. 296:506-513

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Baseline anxiety, and early anxiety/depression improvement in anxious depression predicts treatment outcomes with escitalopram: A CAN-BIND-1 study report

Authors: Khoo, Yuelee, Demchenko, Ilya, Frey, Benicio N., Milev, Roumen V., Ravindran, Arun V., Parikh, Sagar V., Ho, Keith, Rotzinger, Susan, Lou, Wendy, Lam, Raymond W., Kennedy, Sidney H., Bhat, Venkat

Source: Journal of affective disorders. 300:50-58

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155128196.0x000001&indx=1&recIds=ETOCvdc_100155128196.0x000001

Electroconvulsive Therapy in Canada During the First Wave of COVID-19

Authors: Demchenko, Ilya, Blumberger, Daniel M., Flint, Alastair J., Anderson, Melanie, Daskalakis, Zafiris J., Foley, Karen, Karkouti, Keyvan, Kennedy, Sidney H., Ladha, Karim S., Robertson, Jamie, Vaisman, Alon, Koczerginski, David, Parikh, Sagar V., Bhat, Venkat

Source: Journal of ECT. 38(1):52-59

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146578886.0x000001&indx=1&recIds=ETOCvdc_100146578886.0x000001

Combinatorial pharmacogenomic algorithm is predictive of sertraline metabolism in patients with major depressive disorder

Authors: Parikh, Sagar V., Law, Rebecca A., Hain, Daniel T., Rothschild, Anthony J., Thase, Michael E., Dunlop, Boadie W., DeBattista, Charles, Forester, Brent P., Shelton, Richard C., Macaluso, Matthew, Cogan, Elizabeth S., Brown, Krystal, Lewis, David J., Jablonski, Michael R., Greden, John F.

Source: In Psychiatry Research February 2022 308

Evaluating the perceived utility of an artificial intelligence-powered clinical decision support system for depression treatment using a simulation center

Authors: Tanguay-Sela, Myriam, Benrimoh, David, Popescu, Christina, Perez, Tamara, Rollins, Colleen, Snook, Emily, Lundrigan, Eryn, Armstrong, Caitrin, Perlman, Kelly, Fratila, Robert, Mehltretter, Joseph, Israel, Sonia, Champagne, Monique, Williams, Jérôme, Simard, Jade, Parikh, Sagar V., Karp, Jordan F., Heller, Katherine, Linnaranta, Outi, Cardona, Liliana Gomez, Turecki, Gustavo, Margolese, Howard C.

Source: In Psychiatry Research February 2022 308

Hypothalamus volume and DNA methylation of stress axis genes in major depressive disorder: A CAN-BIND study report

Authors: Suh, Jee Su, Fiori, Laura M., Ali, Mohammad, Harkness, Kate L., Ramonas, Milita, Minuzzi, Luciano, Hassel, Stefanie, Strother, Stephen C., Zamyadi, Mojdeh, Arnott, Stephen R., Farzan, Faranak, Foster, Jane A., Lam, Raymond W., MacQueen, Glenda M., Milev, Roumen, Müller, Daniel J., Parikh, Sagar V., Rotzinger, Susan, Sassi, Roberto B., Soares, Claudio N., Uher, Rudolf, Kennedy, Sidney H., Turecki, Gustavo, Frey, Benicio N.

Source: In Psychoneuroendocrinology October 2021 132

Clinical validation of combinatorial pharmacogenomic testing and single-gene guidelines in predicting psychotropic medication blood levels and clinical outcomes in patients with depression

Authors: Rothschild, Anthony J., Parikh, Sagar V., Hain, Daniel, Law, Rebecca, Thase, Michael E., Dunlop, Boadie W., DeBattista, Charles, Conway, Charles R., Forester, Brent P., Shelton, Richard C., Macaluso, Matthew, Brown, Krystal, Lewis, David, Gutin, Alexander, Jablonski, Michael R., Greden, John F.

Source: In Psychiatry Research February 2021 296

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) recommendations for the management of patients with bipolar disorder with mixed presentations

Authors: Yatham, Lakshmi N., Chakrabarty, Trisha, Bond, David J., Schaffer, Ayal, Beaulieu, Serge, Parikh, Sagar V., McIntyre, Roger S., Milev, Roumen V., Alda, Martin, Vazquez, Gustavo, Ravindran, Arun V., Frey, Benicio N., Sharma, Verinder, Goldstein, Benjamin I., Rej, Soham, O'Donovan, Claire, Tourjman, Valerie, Kozicky, Jan‐Marie, Kauer‐Sant'Anna, Marcia, Malhi, Gin, Suppes, Trisha, Vieta, Eduard, Kapczinski, Flavio, Kanba, Shigenobu, Lam, Raymond W., Kennedy, Sidney H., Calabrese, Joseph, Berk, Michael, Post, Robert

Source: Bipolar disorders. 23(8):767-788

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Teaching psychiatric pharmacogenomics effectively: Evaluation of a novel interprofessional online course

Authors: Ward, Kristen M., Taubman, Danielle S., Pasternak, Amy L., Burghardt, Kyle J., Ellingrod, Vicki L., Parikh, Sagar V.

Source: Journal of the American College of Clinical Pharmacy. 4(2):176-183

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120781186.0x000001&indx=1&recIds=ETOCvdc_100120781186.0x000001

Modulation of neural oscillations in escitalopram treatment: a Canadian biomarker integration network in depression study.

Authors: Schwartzmann, Benjamin, Chatterjee, Raaj, Vaghei, Yasaman, Quilty, Lena C., Allen, Timothy A., Arnott, Stephen R., Atluri, Sravya, Blier, Pierre, Dhami, Prabhjot, Foster, Jane A., Frey, Benicio N., Kloiber, Stefan, Lam, Raymond W., Milev, Roumen, Müller, Daniel J., Soares, Claudio N., Stengel, Chloe, Parikh, Sagar V., Turecki, Gustavo, Uher, Rudolf

Source: Translational Psychiatry; 10/12/2024, Vol. 14 Issue 1, p1-11, 11p