A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.

Authors: Goldberg, Joel A., Kumar, Vijay, Spencer, Elizabeth J., Hoyer, Denton, Marshall, Steven H., Hujer, Andrea M., Hujer, Kristine M., Bethel, Christopher R., Papp-Wallace, Krisztina M., Perez, Federico, Jacobs, Michael R., van Duin, David, Kreiswirth, Barry N., van den Akker, Focco, Plummer, Mark S., Bonomo, Robert A.

Source: In European Journal of Medicinal Chemistry 5 August 2021 220

Frameshift Mutations in Genes Encoding PBP3 and PBP4 Trigger an Unusual, Extreme β‑Lactam Resistance Phenotype in Burkholderia multivorans.

Authors: Mojica, Maria F., Nukaga, Michiyoshi, Becka, Scott A., Zeiser, Elise T., Hoshino, Tyuji, LiPuma, John J., Papp-Wallace, Krisztina M.

Source: ACS Infectious Diseases; 11/8/2024, Vol. 10 Issue 11, p3810-3820, 11p

Resistance to Novel β-Lactam–β-Lactamase Inhibitor Combinations: The “Price of Progress”

Authors: Papp-Wallace, Krisztina M., Mack, Andrew R., Taracila, Magdalena A., Bonomo, Robert A.

Source: In Infectious Disease Clinics of North America December 2020 34(4):773-819

Ceftazidime-Avibactam in Combination With Fosfomycin : A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa

Authors: Papp-Wallace, Krisztina M., Zeiser, Elise T., Becka, Scott A., Park, Steven, Wilson, Brigid M., Winkler, Marisa L., D’Souza, Roshan, Singh, Indresh, Sutton, Granger, Fouts, Derrick E., Chen, Liang, Kreiswirth, Barry N., Ellis-Grosse, Evelyn J., Drusano, George L., Perlin, David S., Bonomo, Robert A.

Source: The Journal of Infectious Diseases, 2019 Aug . 220(4), 666-676.

Access URL: https://www.jstor.org/stable/26758754

The latest advances in β-lactam/β-lactamase inhibitor combinations for the treatment of Gram-negative bacterial infections

Authors: Papp-Wallace, Krisztina M.

Source: Expert opinion on pharmacotherapy. 20(17):2169-2184

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091981980.0x000001&indx=1&recIds=ETOCvdc_100091981980.0x000001

A 17-Year Nationwide Study of Burkholderia cepacia Complex Bloodstream Infections Among Patients in the United States Veterans Health Administration

Authors: El Chakhtoura, Nadim G., Saade, Elie, Wilson, Brigid M., Perez, Federico, Papp-Wallace, Krisztina M., Bonomo, Robert A.

Source: Clinical Infectious Diseases, 2017 Oct . 65(8), 1327-1334.

Access URL: https://www.jstor.org/stable/26375756

Sequence heterogeneity of the PenA carbapenemase in clinical isolates of Burkholderia multivorans

Authors: Becka, Scott A., Zeiser, Elise T., Marshall, Steven H., Gatta, Julian A., Nguyen, Kevin, Singh, Indresh, Greco, Chris, Sutton, Granger G., Fouts, Derrick E., LiPuma, John J., Papp-Wallace, Krisztina M.

Source: Diagnostic microbiology and infectious disease. 92(3):253-258

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100068119920.0x000001&indx=1&recIds=ETOCvdc_100068119920.0x000001

New β-Lactamase Inhibitors in the Clinic

Authors: Papp-Wallace, Krisztina M., Bonomo, Robert A.

Source: In Infectious Disease Clinics of North America June 2016 30(2):441-464

Treatment options for infections caused by carbapenem-resistant Enterobacteriaceae: can we apply 'precision medicine' to antimicrobial chemotherapy?

Authors: Perez, Federico, El Chakhtoura, Nadim G., Papp-Wallace, Krisztina M., Wilson, Brigid M., Bonomo, Robert A.

Source: Expert opinion on pharmacotherapy. 17(6):761-781

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106467787.0x000001&indx=1&recIds=ETOCvdc_100106467787.0x000001

Insights into β-Lactamases from Burkholderia Species, Two Phylogenetically Related yet Distinct Resistance Determinants

Authors: Papp-Wallace, Krisztina M., Taracila, Magdalena A., Gatta, Julian A., Ohuchi, Nozomi, Bonomo, Robert A. ^**, Nukaga, Michiyoshi

Source: In Journal of Biological Chemistry 28 June 2013 288(26):19090-19102

Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-β-lactamases

Authors: Mojica, Maria F., Mahler, S. Graciela, Bethel, Christopher R., Taracila, Magdalena A., Kosmopoulou, Magda, Papp-Wallace, Krisztina M., Llarrull, Leticia I., Wilson, Brigid M., Marshall, Steven H., Wallace, Christopher J.

Source: Biochemistry. 54(20):3183-3196

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN601297508&indx=1&recIds=ETOCRN601297508

Exploring the Role of a Conserved Class A Residue in the Ω-Loop of KPC-2 β-Lactamase: A MECHANISM FOR CEFTAZIDIME HYDROLYSIS

Authors: Levitt, Peter S., Papp-Wallace, Krisztina M., Taracila, Magdalena A., Hujer, Andrea M., Winkler, Marisa L., Smith, Kerri M. ^**, Xu, Yan ^**, Harris, Michael E., Bonomo, Robert A.

Source: In Journal of Biological Chemistry 14 September 2012 287(38):31783-31793

Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone

Authors: Papp-Wallace, Krisztina M., Bethel, Christopher R., Gootz, Thomas D., Shang, Wenchi, Stroh, Justin, Lau, William, McLeod, Dale, Price, Loren, Marfat, Anthony, Distler, Anne, Drawz, Sarah M., Chen, Hansong, Harry, Emily, Nottingham, Micheal, Carey, Paul R., Buynak, John D., Bonomo, Robert A.

Source: In Biochemical Pharmacology 2012 83(4):462-471

Human pleural fluid triggers global changes in the transcriptional landscape of Acinetobacter baumannii as an adaptive response to stress

Authors: Martinez, Jasmine, Fernandez, Jennifer S., Liu, Christine, Hoard, Amparo, Mendoza, Anthony, Nakanouchi, Jun, Rodman, Nyah, Courville, Robert, Tuttobene, Marisel R., Lopez, Carolina, Gonzalez, Lisandro J., Shahrestani, Parvin, Papp-Wallace, Krisztina M., Vila, Alejandro J., Tolmasky, Marcelo E., Bonomo, Robert A., Sieira, Rodrigo, Ramirez, Maria Soledad

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131409183.0x000001&indx=1&recIds=ETOCvdc_100131409183.0x000001

Durlobactam, a Broad-Spectrum Serine β-lactamase Inhibitor, Restores Sulbactam Activity Against Acinetobacter Species.

Authors: Papp-Wallace, Krisztina M^1,2 krisztina.papp@va.gov, McLeod, Sarah M³, Miller, Alita A³ krisztina.papp@va.gov

Source: Clinical Infectious Diseases. 2023 Supplement, Vol. 76, pS194-S201. 8p.

Subject Terms: *ACINETOBACTER infections, *PENICILLIN, *BETA lactamases, *GRAM-negative aerobic bacteria, *MICROBIAL sensitivity tests

The Effectiveness of Imipenem–Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase.

Authors: Papp-Wallace, Krisztina M., Barnes, Melissa D., Taracila, Magdalena A., Bethel, Christopher R., Rutter, Joseph D., Zeiser, Elise T., Young, Katherine, Bonomo, Robert A.

Source: Antibiotics (2079-6382); May2023, Vol. 12 Issue 5, p892, 11p

Subject Terms: MOLECULAR models, DEACYLATION, IMIPENEM, CEFTAZIDIME, AMINO acids

Company/Entity: UNITED States. Food & Drug Administration

698. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Multidrug-Resistant Gram-Negative Bacilli

Authors: Goldberg, Joel, Bethel, Christopher, Hujer, Andrea M, Hujer, Kristine, Marshall, Steven, Papp-Wallace, Krisztina M, Perez, Federico, Spencer, Elizabeth, Hoyer, Denton, Plummer, Mark, Bonomo, Robert A

Source: Open forum infectious diseases. 6(Supplement 2):S315-S316

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100049893.0x000001&indx=1&recIds=ETOCvdc_100100049893.0x000001

Regulation of CorA Mg2+ Channel Function Affects the Virulence of Salmonella enterica Serovar Typhimurium.

Authors: Papp-Wallace, Krisztina M., Maguire, Michael E.

Source: Journal of Bacteriology; October 2008, Vol. 190 Issue 19, p6509-6516, 8p

The CorA Mg2+ Channel Is Required for the Virulence of Salmonella enterica Serovar Typhimurium.

Authors: Papp-Wallace, Krisztina M., Nartea, Margaret, Kehres, David G.

Source: Journal of Bacteriology; October 2008, Vol. 190 Issue 19, p6517-6523, 7p

Manganese Transport and the Role of Manganese in Virulence.

Authors: Papp-Wallace, Krisztina M., Maguire, Michael E.

Source: Annual Review of Microbiology; 2006, Vol. 60, p187-209, 23p