The effect of intermittent mixing on the rate of drying of L-threonine in an agitated filter dryer

Authors: Chaksmithanont, Prin ^{a, b}, Alves, Marcella R. ^a, Khinast, Johannes G. ^c, Papageorgiou, Charles D. ^d, Mitchell, Christopher ^d, Quon, Justin L. ^d, Glasser, Benjamin J. ^{a, ⁎}

Source: In Advanced Powder Technology January 2025 36(1)

Machine Learning-Derived Correlations for Scale-Up and Technology Transfer of Primary Nucleation Kinetics

Authors: Yerdelen, Stephanie, Yang, Yihui, Quon, Justin L., Papageorgiou, Charles D., Mitchell, Chris, Houson, Ian, Sefcik, Jan, Horst, Joop H. ter, Florence, Alastair J., Brown, Cameron J.

Source: Crystal growth & design. 23(2):681-693

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631675413&indx=1&recIds=ETOCRN631675413

The effect of intermittent mixing on particle heat transfer in an agitated dryer

Authors: Chaksmithanont, Prin, McEntee, Gabrielle, Hartmanshenn, Clara, Leung, Carlin, Khinast, Johannes G., Papageorgiou, Charles D., Mitchell, Christopher, Quon, Justin L., Glasser, Benjamin J.

Source: In Powder Technology 15 May 2023 422

Optimization-based digital design of a commercial pharmaceutical crystallization process for size and shape control
European symposium on computer aided process engineering

Authors: Eren, Ayşe, Szilagyi, Botond, Quon, Justin L., Papageorgiou, Charles D., Nagy, Zoltan K.

Source: Computer-aided chemical engineering. 50(2):1143-1148

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN607097871&indx=1&recIds=ETOCCN607097871

Use of Wet Milling Combined with Temperature Cycling to Minimize Crystal Agglomeration in a Sequential Antisolvent—Cooling Crystallization

Authors: Sun, Zhuang, Quon, Justin L., Papageorgiou, Charles D., Benyahia, Brahim, Rielly, Chris D.

Source: Crystal growth & design. 22(8):4730-4744

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632116687&indx=1&recIds=ETOCRN632116687

Digital Design of the Crystallization of an Active Pharmaceutical Ingredient Using a Population Balance Model with a Novel Size Dependent Growth Rate Expression. From Development of a Digital Twin to In Silico Optimization and Experimental Validation

Authors: Szilágyi, Botond, Eren, Ayşe, Quon, Justin L., Papageorgiou, Charles D., Nagy, Zoltán K.

Source: Crystal growth & design. 22(1):497-512

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632112372&indx=1&recIds=ETOCRN632112372

Monitoring and digital design of the cooling crystallization of a high-aspect ratio anticancer drug using a two-dimensional population balance model

Authors: Szilágyi, Botond, Eren, Ayşe, Quon, Justin L., Papageorgiou, Charles D., Nagy, Zoltán K.

Source: In Chemical Engineering Science 10 August 2022 257

Scale-up of granular material flow in an agitated filter dryer

Authors: Chaksmithanont, Prin, Milman, Felix, Leung, Carlin, Khinast, Johannes G., Papageorgiou, Charles D., Mitchell, Christopher, Quon, Justin L., Glasser, Benjamin J.

Source: In Powder Technology July 2022 407

Scale up of heat transfer for dry granular material in a cylindrical bladed mixer

Authors: Hartmanshenn, Clara, Halota, Madeline, Chaksmithanont, Prin, Leung, Carlin, Khinast, Johannes G., Papageorgiou, Charles D., Mitchell, Christopher, Quon, Justin L., Glasser, Benjamin J.

Source: In Powder Technology June 2021 385:336-347

Investigation of Wet Milling and Indirect Ultrasound as Means for Controlling Nucleation in the Continuous Crystallization of an Active Pharmaceutical Ingredient

Authors: Yang, Yihui, Ahmed, Bilal, Mitchell, Christopher, Quon, Justin L., Siddique, Humera, Houson, Ian, Florence, Alastair J., Papageorgiou, Charles D.

Source: Organic process research & development. 25(9):2119-2132

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627663400&indx=1&recIds=ETOCRN627663400

Experimental Investigation of an Integrated Crystallization and Wet-Milling System with Temperature Cycling to Control the Size and Aspect Ratio of Needle-Shaped Pharmaceutical Crystals

Authors: Eren, Ayse, Szilagyi, Botond, Quon, Justin L., Papageorgiou, Charles D., Nagy, Zoltan K.

Source: Crystal growth & design. 21(7):3981-3993

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632061119&indx=1&recIds=ETOCRN632061119

Development of a Novel Screening Methodology for the Assessment of the Risk of Particle Size Attrition during Agitated Drying

Authors: Papageorgiou, Charles D., Mitchell, Christopher, Quon, Justin L., Langston, Marianne, Borg, Suzanna, Hicks, Frederick, Ende, David am, Breault, Mark

Source: Organic process research & development. 24(2):242-254

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623689874&indx=1&recIds=ETOCRN623689874

Application of Model-Free and Model-Based Quality-by-Control (QbC) for the Efficient Design of Pharmaceutical Crystallization Processes

Authors: Szilagyi, Botond, Eren, Ayse, Quon, Justin L., Papageorgiou, Charles D., Nagy, Zoltan K.

Source: Crystal growth & design. 20(6):3979-3996

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631966649&indx=1&recIds=ETOCRN631966649

Infrared temperature measurements and DEM simulations of heat transfer in a bladed mixer.

Authors: Hartmanshenn, Clara¹, Chaksmithanont, Prin¹, Leung, Carlin¹, Ghare, Digvijay V.¹, Chakraborty, Nabaneeta¹, Patel, Sagar¹, Halota, Madeline¹, Khinast, Johannes G.², Papageorgiou, Charles D.³, Mitchell, Chris³, Quon, Justin L.³, Glasser, Benjamin J.¹, bglasser@rutgers.edu

Source: AIChE Journal; Jul2022, Vol. 68 Issue 7, p1-16, 16p

Multi-objective reinforcement learning for self-optimization of flow chemistry

Authors: Yewale, Ashish ^a, Yang, Yihui ^b, Nazemifard, Neda ^b, Papageorgiou, Charles D. ^b, Rielly, Chris D. ^a, Benyahia, Brahim ^a

Source: In Computer Aided Chemical Engineering 2024 53:3031-3036

Development and Scale-Up of a Crystallization Process To Improve an API's Physiochemical and Bulk Powder Properties

Authors: Durak, Landon, Kennedy, Miriam, Langston, Marianne, Mitchell, Christopher, Morris, Gary, Perlman, Michael E., Wendl, Kaitlyn, Hicks, Frederick, Papageorgiou, Charles D.

Source: Organic process research & development. 22(3):296-305

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN615297562&indx=1&recIds=ETOCRN615297562

Development and Scale-up of a Flow Chemistry Lithiation—Borylation Route to a Key Boronic Acid Starting Material

Authors: Usutani, Hirotsugu, Nihei, Takashi, Papageorgiou, Charles D., Cork, David G.

Source: Organic process research & development. 21(4):669-673

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN611001597&indx=1&recIds=ETOCRN611001597

The Enabling Technologies Consortium (ETC): Fostering Precompetitive Collaborations on New Enabling Technologies for Pharmaceutical Research and Development

Authors: Welch, Christopher J., Faul, Margaret M., Tummala, Srinivas, Papageorgiou, Charles D., Hicks, Frederick, Hawkins, Joel M., Thomson, Nicholas, Cote, Aaron, Bordawekar, Shailendra, Wittenberger, Steven J.

Source: Organic process research & development. 21(3):414-419

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN610513011&indx=1&recIds=ETOCRN610513011

Heat transfer of dry granular materials in a bladed mixer:Effect of thermal properties and agitation rate.

Authors: Hartmanshenn, Clara¹, Khinast, Johannes G.², Papageorgiou, Charles D.³, Mitchell, Chris³, Quon, Justin³, Glasser, Benjamin J.¹, bglasser@rutgers.edu

Source: AIChE Journal; Apr2020, Vol. 66 Issue 4, p1-15, 15p

Development of Screening Methodology for the Assessment of the Agglomeration Potential of APIs

Authors: Papageorgiou, Charles D., Langston, Marianne, Hicks, Frederick, Ende, David am, Martin, Eric, Rothstein, Sarah, Salan, Jerry, Muir, Robert

Source: Organic process research & development. 20(8):1500-1508

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN607710260&indx=1&recIds=ETOCRN607710260