Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection

Authors: Koenecke, Allison, Powell, Michael, Xiong, Ruoxuan, Shen, Zhu, Fischer, Nicole, Huq, Sakibul, Khalafallah, Adham M., Trevisan, Marco, Sparen, Pär, Carrero, Juan J, Nishimura, Akihiko, Caffo, Brian, Stuart, Elizabeth A., Bai, Renyuan, Staedtke, Verena, Thomas, David L., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin, Bettegowda, Chetan, Konig, Maximilian F., Mensh, Brett, Vogelstein, Joshua T., Athey, Susan

Source: Elife 10 (2021): e61700

Subject Terms: Quantitative Biology - Tissues and Organs, Quantitative Biology - Quantitative Methods

Access URL: http://arxiv.org/abs/2004.10117

Multicancer early detection test: Preclinical, translational, and clinical evidence–generation plan and provocative questions

Authors: Kisiel, John B., Papadopoulos, Nickolas, Liu, Minetta C., Crosby, David, Srivastava, Sudhir, Hawk, Ernest T.

Source: Cancer. 128:861-874

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140390283.0x000001&indx=1&recIds=ETOCvdc_100140390283.0x000001

Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape.

Authors: Cook, Ashley L., Sur, Surojit, Dobbyn, Laura, Watson, Evangeline, Cohen, Joshua D., Ptak, Blair, Bum Seok Lee, Paul, Suman, Hsiue, Emily, Popoli, Maria, Vogelstein, Bert, Papadopoulos, Nickolas, Bettegowda, Chetan, Gabrielson, Kathy, Zhou, Shibin, Kinzler, Kenneth W., Wyhs, Nicolas

Source: eLife; 2/17/2025, p1-32, 32p

Taming Lynch Syndrome: The Remarkable Power of Prevention for One Family.

Authors: Yurgelun, Matthew B., Rhees, Jennifer, Papadopoulos, Nickolas, Vogelstein, Bert, Boland, C. Richard

Source: Gastroenterology (0016-5085); Feb2025, Vol. 168 Issue 2, p195-199, 5p

Targeting loss of heterozygosity for cancer-specific immunotherapy

Authors: Hwang, Michael S., Mog, Brian J., Douglass, Jacqueline, Pearlman, Alexander H., Hsiue, Emily Han-Chung, Paul, Suman, DiNapoli, Sarah R., Konig, Maximilian F., Pardoll, Drew M., Gabelli, Sandra B., Bettegowda, Chetan, Papadopoulos, Nickolas, Vogelstein, Bert, Zhou, Shibin, Kinzler, Kenneth W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(12), 1-10.

Access URL: https://www.jstor.org/stable/27039563

Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer: 5-year outcomes of the randomized DYNAMIC trial

Authors: Tie, Jeanne, Wang, Yuxuan, Lo, Serigne N., Lahouel, Kamel, Cohen, Joshua D., Wong, Rachel, Shapiro, Jeremy D., Harris, Samuel J., Khattak, Adnan, Burge, Matthew E., Lee, Margaret, Harris, Marion, McLachlan, Sue-Anne, Horvath, Lisa, Karapetis, Christos, Shannon, Jenny, Singh, Madhu, Yip, Desmond, Ananda, Sumitra, Underhill, Craig, Ptak, Janine, Silliman, Natalie, Dobbyn, Lisa, Popoli, Maria, Papadopoulos, Nickolas, Tomasetti, Cristian, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter

Source: Nature Medicine; 20250101, Issue: Preprints p1-10, 10p

Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett’s Esophagus

Authors: Douville, Christopher, Moinova, Helen R., Thota, Prashanthi N., Shaheen, Nicholas J., Iyer, Prasad G., Canto, Marcia Irene, Wang, Jean S., Dumot, John A., Faulx, Ashley, Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert, Markowitz, Sanford D., Bettegowda, Chetan, Willis, Joseph E., Chak, Amitabh

Source: In Gastroenterology May 2021 160(6):2043-2054

Ultrasensitive detection of tumor‐specific mutations in saliva of patients with oral cavity squamous cell carcinoma

Authors: Shanmugam, Ashwini, Hariharan, Arun K., Hasina, Rifat, Nair, Jayalakshmi R., Katragadda, Shanmukh, Irusappan, Sivaraj, Ravichandran, Aarthi, Veeramachaneni, Vamsi, Bettadapura, Radhakrishna, Bhati, Muddasir, Ramaswamy, Veena, Rao, Vishal U. S., Bagadia, Ritvi K., Manjunath, Ashwini, Manjunath, N. M. L., Solomon, Monica Charlotte, Maji, Shiuli, Bahadur, Urvashi, Bettegowda, Chetan, Papadopoulos, Nickolas, Lingen, Mark W., Hariharan, Ramesh, Gupta, Vaijayanti, Agrawal, Nishant, Izumchenko, Evgeny

Source: Cancer. 127(10):1576-1589

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121032596.0x000001&indx=1&recIds=ETOCvdc_100121032596.0x000001

Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies

Authors: Tie, Jeanne, Cohen, Joshua D., Lo, Serigne N., Wang, Yuxuan, Li, Lu, Christie, Michael, Lee, Margaret, Wong, Rachel, Kosmider, Suzanne, Skinner, Iain, Wong, Hui Li, Lee, Belinda, Burge, Matthew E., Yip, Desmond, Karapetis, Christos S., Price, Timothy J., Tebbutt, Niall C., Haydon, Andrew M., Ptak, Janine, Schaeffer, Mary J., Silliman, Natalie, Dobbyn, Lisa, Popoli, Maria, Tomasetti, Cristian, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter

Source: International journal of cancer. 148(4):1014-1026

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111853847.0x000001&indx=1&recIds=ETOCvdc_100111853847.0x000001

Pre-malignant conditions diagnosed following a positive cancer signal from a multi-cancer early detection test.

Authors: Choudhry, Omair A., Kharge, Angana B., Rego, Seema P., Elias, Paul Z., Buchanan, Adam H., Lennon, Anne Marie, Papadopoulos, Nickolas, Diehl, Frank, Beer, Tomasz M.

Source: Frontiers in Oncology; 2024, p1-6, 6p

Subject Terms: POSITRON emission tomography computed tomography, ELECTRONIC health records, PRECANCEROUS conditions, BLOOD collection, BLOOD testing, CYSTADENOMA

Assessing aneuploidy with repetitive element sequencing

Authors: Douville, Christopher, Cohen, Joshua D., Ptak, Janine, Popoli, Maria, Schaefer, Joy, Silliman, Natalie, Dobbyn, Lisa, Schoen, Robert E., Tie, Jeanne, Gibbs, Peter, Goggins, Michael, Wolfgang, Christopher L., Wang, Tian-Li, Shih, Ie-Ming, Karchin, Rachel, Lennon, Anne Marie, Hruban, Ralph H., Tomasetti, Cristian, Bettegowda, Chetan, Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Mar 01. 117(9), 4858-4863.

Access URL: https://www.jstor.org/stable/26929182

An engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation

Authors: Miller, Michelle S., Douglass, Jacqueline, Hwang, Michael S., Skora, Andrew D., Murphy, Michael, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin, Gabelli, Sandra B. ^**

Source: In Journal of Biological Chemistry 13 December 2019 294(50):19322-19334

Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma

Authors: Eich, Marie-Lisa, Rodriguez Pena, Maria Del Carmen, Springer, Simeon U., Taheri, Diana, Tregnago, Aline C., Salles, Daniela C., Bezerra, Stephania Martins, Cunha, Isabela W., Fujita, Kazutoshi, Ertoy, Dilek, Bivalacqua, Trinity J., Tomasetti, Cristian, Papadopoulos, Nickolas, Kinzler, Ken W., Vogelstein, Bert, Netto, George J.

Source: In Modern Pathology October 2019 32(10):1544-1550

Pathophysiology of ctDNA Release into the Circulation and Its Characteristics: What Is Important for Clinical Applications

Authors: Papadopoulos, Nickolas

Source: Recent results in cancer research. 215:163-180

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621946400&indx=1&recIds=ETOCRN621946400

Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology

Authors: Rodriguez Pena, Maria Del Carmen, Springer, Simeon U., Taheri, Diana, Li, Lu, Tregnago, Aline C., Eich, Marie-Lisa, Eltoum, Isam-Eldin A., VandenBussche, Christopher J., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Netto, George J.

Source: Virchows Archiv. 476(3):423-429

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168023055.0x000001&indx=1&recIds=ETOCvdc_100168023055.0x000001

Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations

Authors: Palsgrove, Doreen N., Taheri, Diana, Springer, Simeon U., Cowan, Morgan, Guner, Gunes, Mendoza Rodriguez, Maria A., Rodriguez Pena, Maria Del Carmen, Wang, Yuxuan, Kinde, Isaac, Ricardo, Bernardo F.P., Cunha, Isabela, Fujita, Kazutoshi, Ertoy, Dilek, Kinzler, Kenneth W., Bivalacqua, Trinity J., Papadopoulos, Nickolas, Vogelstein, Bert, Netto, George J.

Source: In Human Pathology March 2019 85:1-9

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Authors: Smith, Kellie, Llosa, Nicolas, Cottrell, Tricia, Siegel, Nicholas, Fan, Hongni, Suri, Prerna, Chan, Hok, Guo, Haidan, Oke, Teniola, Awan, Anas, Verde, Franco, Danilova, Ludmila, Anagnostou, Valsamo, Tam, Ada, Luber, Brandon, Bartlett, Bjarne, Aulakh, Laveet, Sidhom, John-William, Zhu, Qingfeng, Sears, Cynthia, Cope, Leslie, Sharfman, William H., Thompson, Elizabeth D., Riemer, Joanne, Marrone, Kristen, Naidoo, Jarushka, Velculescu, Victor, Forde, Patrick, Vogelstein, Bert, Kinzler, Kenneth, Papadopoulos, Nickolas, Durham, Jennifer, Wang, Hao, Le, Dung, Justesen, Sune, Taube, Janis, Diaz, Luis, Brahmer, Julie, Pardoll, Drew, Anders, Robert, Housseau, Franck

Source: Journal for immunotherapy of cancer. 7(1):1-8

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186497122.0x000001&indx=1&recIds=ETOCvdc_100186497122.0x000001

The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with nonspecific findings on standard investigations

Authors: Wong, Rachel, Tie, Jeanne, Lee, Margaret, Cohen, Joshua, Wang, Yuxuan, Li, Lu, Ma, Stephen, Christie, Michael, Kosmider, Suzanne, Tomasetti, Cristian, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter

Source: International journal of cancer. 145(2):540-547

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083714351.0x000001&indx=1&recIds=ETOCvdc_100083714351.0x000001

Detection and localization of surgically resectable cancers with a multi-analyte blood test

Authors: Cohen, Joshua D., Li, Lu, Wang, Yuxuan, Thoburn, Christopher, Afsari, Bahman, Danilova, Ludmila, Douville, Christopher, Javed, Ammar A., Wong, Fay, Mattox, Austin, Hruban, Ralph. H., Wolfgang, Christopher L., Goggins, Michael G., Dal Molin, Marco, Wang, Tian-Li, Roden, Richard, Klein, Alison P., Ptak, Janine, Dobbyn, Lisa, Schaefer, Joy, Silliman, Natalie, Popoli, Maria, Vogelstein, Joshua T., Browne, James D., Schoen, Robert E., Brand, Randall E., Tie, Jeanne, Gibbs, Peter, Wong, Hui-Li, Mansfield, Aaron S., Jen, Jin, Hanash, Samir M., Falconi, Massimo, Allen, Peter J., Zhou, Shibin, Bettegowda, Chetan, Diaz, Luis A., Tomasetti, Cristian, Kinzler, Kenneth W., Vogelstein, Bert, Lennon, Anne Marie, Papadopoulos, Nickolas

Source: Science, 2018 Feb . 359(6378), 926-930.

Access URL: https://www.jstor.org/stable/26401546

Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs)

Authors: Douville, Christopher, Springer, Simeon, Kinde, Isaac, Cohen, Joshua D., Hruban, Ralph H., Lennon, Anne Marie, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Karchin, Rachel

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Feb . 115(8), 1871-1876.

Access URL: https://www.jstor.org/stable/26507573