Ex Vivo and In Vitro Proteomic Approach to Elucidate the Relevance of IL‐4 and IL‐10 in Intervertebral Disc Pathophysiology

Authors: Paola Bermudez‐Lekerika, Sofia Tseranidou, Exarchos Kanelis, Andrea Nüesch, Katherine B. Crump, Leonidas G. Alexopoulos, Karin Wuertz‐Kozak, Jérôme Noailly, Christine L. Le Maitre, Benjamin Gantenbein

Source: JOR Spine, Vol 8, Iss 1, Pp n/a-n/a (2025)

Subject Terms: immunohistochemistry, interleukin‐10, interleukin‐4, intervertebral disc, low back pain, secretome proteomics, Orthopedic surgery, RD701-811

File Description: electronic resource

Relation: https://doaj.org/toc/2572-1143

Access URL: https://doaj.org/article/1b80e9c4ae7c4d7ea34f1b3eb33a1a1a

Correction: Bermudez-Lekerika et al. Sulfated Hydrogels as Primary Intervertebral Disc Cell Culture Systems. Gels 2024, 10, 330

Authors: Paola Bermudez-Lekerika, Katherine B. Crump, Karin Wuertz-Kozak, Christine L. Le Maitre, Benjamin Gantenbein

Source: Gels, Vol 10, Iss 10, p 612 (2024)

Subject Terms: n/a, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/10/10/612; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/65243cd8c9fa4c1db4b2cdddd98384fe

Cartilaginous endplates: A comprehensive review on a neglected structure in intervertebral disc research

Authors: Katherine B. Crump, Ahmad Alminnawi, Paola Bermudez‐Lekerika, Roger Compte, Francesco Gualdi, Terence McSweeney, Estefano Muñoz‐Moya, Andrea Nüesch, Liesbet Geris, Stefan Dudli, Jaro Karppinen, Jérôme Noailly, Christine Le Maitre, Benjamin Gantenbein

Source: JOR Spine, Vol 6, Iss 4, Pp n/a-n/a (2023)

Subject Terms: biologic therapies, biomechanics, degeneration, pre‐clinical models, Orthopedic surgery, RD701-811

File Description: electronic resource

Relation: https://doaj.org/toc/2572-1143

Access URL: https://doaj.org/article/5b4478ce19fc4886978a62ecc9211dac

Sulfated Hydrogels as Primary Intervertebral Disc Cell Culture Systems

Authors: Paola Bermudez-Lekerika, Katherine B. Crump, Karin Wuertz-Kozak, Christine L. Le Maitre, Benjamin Gantenbein

Source: Gels, Vol 10, Iss 5, p 330 (2024)

Subject Terms: intervertebral disc, sulfation alginate, 3D culture, qPCR, cell viability, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/10/5/330; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/c95ae15b2486494a9b2f2f801f5f3806

The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance

Authors: Sophia N. Verouti, Jonai Pujol-Giménez, Paola Bermudez-Lekerika, Laeticia Scherler, Rajesh Bhardwaj, Aurélien Thomas, Sébastien Lenglet, Mark Siegrist, Willy Hofstetter, Daniel G. Fuster, Matthias A. Hediger, Geneviève Escher, Bruno Vogt

Source: Frontiers in Physiology, Vol 13 (2022)

Subject Terms: ZIP8, blood pressure, glucose, SLC39A8, rs13107325, divalent metal ions, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.912277/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/4dd0962652ae49ec91bde16de4444a7d

Immuno-Modulatory Effects of Intervertebral Disc Cells

Authors: Paola Bermudez-Lekerika, Katherine B. Crump, Sofia Tseranidou, Andrea Nüesch, Exarchos Kanelis, Ahmad Alminnawi, Laura Baumgartner, Estefano Muñoz-Moya, Roger Compte, Francesco Gualdi, Leonidas G. Alexopoulos, Liesbet Geris, Karin Wuertz-Kozak, Christine L. Le Maitre, Jérôme Noailly, Benjamin Gantenbein

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: intervertebral disc degeneration, low back pain, inflammation, catabolism, immune-privileged microenvironment, GWAS, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.924692/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/15f20c230e9b49f080b2b6b86432f7e5

Sulfated Hydrogels in Intervertebral Disc and Cartilage Research

Authors: Emily Lazarus, Paola Bermudez-Lekerika, Daniel Farchione, Taylor Schofield, Sloan Howard, Iskender Mambetkadyrov, Mikkael Lamoca, Iris V. Rivero, Benjamin Gantenbein, Christopher L. Lewis, Karin Wuertz-Kozak

Source: Cells, Vol 10, Iss 12, p 3568 (2021)

Subject Terms: chondroitin sulfate, heparan sulfate, sulfated hyaluronan, sulfated alginate, sustained release of growth factors, chondrogenic phenotype, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/12/3568; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/1cbb8cdbd4f24414965564e6452d657b

Establishment of a Novel Method for Spinal Discectomy Surgery in Elderly Rats in an In Vivo Spinal Fusion Model

Authors: Katharina A. C. Oswald, Sebastian F. Bigdon, Andreas S. Croft, Paola Bermudez-Lekerika, Alessandra Bergadano, Benjamin Gantenbein, Christoph E. Albers

Source: Methods and Protocols, Vol 4, Iss 4, p 79 (2021)

Subject Terms: spine, spinal fusion, rat, animal experiment, rat anaesthesia, rat surgery, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2409-9279/4/4/79; https://doaj.org/toc/2409-9279

Access URL: https://doaj.org/article/42405a8db17d4a95980d82664c6f5b3f

EGR2, IGF1 and IL6 Expression Are Elevated in the Intervertebral Disc of Patients Suffering from Diffuse Idiopathic Skeletal Hyperostosis (DISH) Compared to Degenerative or Trauma Discs

Authors: Benjamin Gantenbein, Rahel D. May, Paola Bermudez-Lekerika, Katharina A. C. Oswald, Lorin M. Benneker, Christoph E. Albers

Source: Applied Sciences, Vol 11, Iss 9, p 4072 (2021)

Subject Terms: low back pain, diffuse idiopathic skeletal hyperostosis, RNA extraction, qPCR, TGFβ-pathway, immune-histochemistry, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/11/9/4072; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/1b4a12e6f7d649208276b6cc805e6575