Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants

Authors: Arias, Angelo D., Benaglio, Paola, Berggren, W. Travis, Borja, Victor, Cook, Megan, DeBoever, Christopher, Diffenderfer, Kenneth E., Donovan, Margaret K.R., Farnam, KathyJean, Fujita, Kyohei, Garcia, Melvin, Harismendy, Olivier, Jakubosky, David, Jepsen, Kristen, Joshua, Isaac, Li, He, Matsui, Hiroko, McCarron, Angelina, Nariai, Naoki, O’Connor, Daniel T., Okubo, Jonathan, Rao, Fengwen, Reyna, Joaquin, Aguiar, Lana Ribeiro, Salgado, Bianca M., Silva, Nayara, Smith, Erin N., Sohmer, Josh, Yost, Shawn, Young Greenwald, William W., Arthur, Timothy D. ^{1, 2, 11}, Nguyen, Jennifer P. ^{2, 3, 11}, Henson, Benjamin A. ⁴, D'Antonio-Chronowska, Agnieszka ⁵, Jaureguy, Jeffrey ^{3, 6}, Panopoulos, Athanasia D. ^{8, 9}, Izpisua Belmonte, Juan Carlos ¹⁰, D’Antonio, Matteo ², McVicker, Graham ⁶, Frazer, Kelly A. ^{4, 7, 12, ∗}

Source: In Cell Genomics 12 March 2025 5(3)

A nanotherapeutic approach to selectively eliminate metastatic breast cancer cells by targeting cell surface GRP78Electronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3nr00800b

Authors: Shin, Jaeho, Kim, Baksun, Lager, Tyson W., Mejia, Franklin, Guldner, Ian, Conner, Clay, Zhang, Siyuan, Panopoulos, Athanasia D., Bilgicer, Basar

Source: Nanoscale. 15(32):13322-13334

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190362948.0x000001&indx=1&recIds=ETOCvdc_100190362948.0x000001

Generation of three induced pluripotent stem cell lines from a patient with Kabuki syndrome carrying the KMT2D p.R4198X mutation

Authors: Lager, Tyson W., Zuo, Junjun, Alam, Md Suhail, Calhoun, Barbara, Haldar, Kasturi, Panopoulos, Athanasia D.

Source: Stem cell research. 62

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188122202.0x000001&indx=1&recIds=ETOCvdc_100188122202.0x000001

iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types

Authors: Panopoulos, Athanasia D., D'Antonio, Matteo, Benaglio, Paola, Williams, Roy, Hashem, Sherin I., Schuldt, Bernhard M., DeBoever, Christopher, Arias, Angelo D., Garcia, Melvin, Nelson, Bradley C., Harismendy, Olivier, Jakubosky, David A., Donovan, Margaret K.R., Greenwald, William W., Farnam, KathyJean, Cook, Megan, Borja, Victor, Miller, Carl A., Grinstein, Jonathan D., Drees, Frauke, Okubo, Jonathan, Diffenderfer, Kenneth E., Hishida, Yuriko, Modesto, Veronica, Dargitz, Carl T., Feiring, Rachel, Zhao, Chang, Aguirre, Aitor, McGarry, Thomas J., Matsui, Hiroko, Li, He, Reyna, Joaquin, Rao, Fangwen, O'Connor, Daniel T., Yeo, Gene W., Evans, Sylvia M., Chi, Neil C., Jepsen, Kristen, Nariai, Naoki, Müller, Franz-Josef, Goldstein, Lawrence S.B., Izpisua Belmonte, Juan Carlos, Adler, Eric, Loring, Jeanne F., Berggren, W. Travis, D'Antonio-Chronowska, Agnieszka, Smith, Erin N., Frazer, Kelly A.

Source: In Stem Cell Reports 11 April 2017 8(4):1086-1100

High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells

Authors: D'Antonio, Matteo, Woodruff, Grace, Nathanson, Jason L., D'Antonio-Chronowska, Agnieszka, Arias, Angelo, Matsui, Hiroko, Williams, Roy, Herrera, Cheryl, Reyna, Sol M., Yeo, Gene W., Goldstein, Lawrence S.B., Panopoulos, Athanasia D., Frazer, Kelly A.

Source: In Stem Cell Reports 11 April 2017 8(4):1101-1111

An iPSC line derived from a human acute myeloid leukemia cell line (HL-60-iPSC) retains leukemic abnormalities and displays myeloid differentiation defects

Authors: Yamasaki, Amanda E., Warshaw, Jane N., Kyalwazi, Beverly L., Matsui, Hiroko, Jepsen, Kristen, Panopoulos, Athanasia D.

Source: Stem cell research. 49

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193464208.0x000001&indx=1&recIds=ETOCvdc_100193464208.0x000001

Cell surface GRP78 promotes stemness in normal and neoplastic cells

Authors: Conner, Clay, Lager, Tyson W., Guldner, Ian H., Wu, Min-Zu, Hishida, Yuriko, Hishida, Tomoaki, Ruiz, Sergio, Yamasaki, Amanda E., Gilson, Robert C., Belmonte, Juan Carlos Izpisua, Gray, Peter C., Kelber, Jonathan A., Zhang, Siyuan, Panopoulos, Athanasia D.

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164212981.0x000001&indx=1&recIds=ETOCvdc_100164212981.0x000001

Generation of a Drug-inducible Reporter System to Study Cell Reprogramming in Human Cells

Authors: Ruiz, Sergio, Panopoulos, Athanasia D., Montserrat, Nuria, Multon, Marie-Christine, Daury, Aurélie, Rocher, Corinne, Spanakis, Emmanuel, Batchelder, Erika M., Orsini, Cécile, Deleuze, Jean-François, Izpisua Belmonte, Juan Carlos

Source: In Journal of Biological Chemistry 23 November 2012 287(48):40767-40778

Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells

Authors: Ruiz, Sergio, Diep, Dinh, Gore, Athurva, Panopoulos, Athanasia D., Montserrat, Nuria, Plongthongkum, Nongluk, Kumar, Sachin, Fung, Ho-Lim, Giorgetti, Alessandra, Bilic, Josipa, Batchelder, Erika M., Zaehres, Holm, Kan, Natalia G., Schöler, Hans Robert, Mercola, Mark, Zhang, Kun, Belmonte, Juan Carlos Izpisua

Source: Proceedings of the National Academy of Sciences of the United States of America, 2012 Oct 01. 109(40), 16196-16201.

Access URL: https://www.jstor.org/stable/41763225

Two iPSC lines generated from the bone marrow of a relapsed/refractory AML patient display normal karyotypes and myeloid differentiation potential

Authors: Yamasaki, Amanda E., King, Nicholas E., Matsui, Hiroko, Jepsen, Kristen, Panopoulos, Athanasia D.

Source: Stem cell research. 41

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096492026.0x000001&indx=1&recIds=ETOCvdc_100096492026.0x000001

STAT3 controls myeloid progenitor growth during emergency granulopoiesis

Authors: Zhang, Huiyuan, Nguyen-Jackson, Hoainam, Panopoulos, Athanasia D., Li, Haiyan S., Murray, Peter J., Watowich, Stephanie S. ^*

Source: In Blood 7 October 2010 116(14):2462-2471

STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF–induced CXCR2 expression and via modulation of CXCR2 signal transduction

Authors: Nguyen-Jackson, Hoainam, Panopoulos, Athanasia D., Zhang, Huiyuan, Li, Haiyan S., Watowich, Stephanie S. ^*

Source: In Blood 22 April 2010 115(16):3354-3363

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

Authors: Yang, Xuexian O., Pappu, Bhanu P., Nurieva, Roza, Akimzhanov, Askar, Kang, Hong Soon, Chung, Yeonseok, Ma, Li, Shah, Bhavin, Panopoulos, Athanasia D., Schluns, Kimberly S., Watowich, Stephanie S., Tian, Qiang, Jetten, Anton M., Dong, Chen

Source: In Immunity 2008 28(1):29-39

Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and ‘emergency’ hematopoiesis

Authors: Panopoulos, Athanasia D., Watowich, Stephanie S.

Source: In Cytokine 2008 42(3):277-288

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

Authors: Kile, Benjamin T. ^*, Panopoulos, Athanasia D., Stirzaker, Roslynn A., Hacking, Douglas F., Tahtamouni, Lubna H., Willson, Tracy A., Mielke, Lisa A., Henley, Katya J., Zhang, Jian-Guo, Wicks, Ian P., Stevenson, William S., Nurden, Paquita, Watowich, Stephanie S., Justice, Monica J.

Source: In Blood 1 October 2007 110(7):2371-2380

STAT3 Regulates Cytokine-mediated Generation of Inflammatory Helper T Cells

Authors: Yang, Xuexian O., Panopoulos, Athanasia D., Nurieva, Roza, Chang, Seon Hee, Wang, Demin, Watowich, Stephanie S., Dong, Chen

Source: In Journal of Biological Chemistry 30 March 2007 282(13):9358-9363

STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils

Authors: Panopoulos, Athanasia D., Zhang, Ling, Snow, Jonathan W., Jones, Daniel M., Smith, Amber M., El Kasmi, Karim C., Liu, Fulu, Goldsmith, Mark A., Link, Daniel C., Murray, Peter J., Watowich, Stephanie S.

Source: In Blood 1 December 2006 108(12):3682-3690

Aberrant DNA Methylation in Human iPSCs Associates with MYC-Binding Motifs in a Clone-Specific Manner Independent of Genetics

Authors: Panopoulos, Athanasia D., Smith, Erin N., Arias, Angelo D., Shepard, Peter J., Hishida, Yuriko, Modesto, Veronica, Diffenderfer, Kenneth E., Conner, Clay, Biggs, William, Sandoval, Efren, D’Antonio-Chronowska, Agnieszka, Berggren, W. Travis, Izpisua Belmonte, Juan Carlos, Frazer, Kelly A.

Source: Cell stem cell. 20(4):505-517.e6

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100052461645.0x000001&indx=1&recIds=ETOCvdc_100052461645.0x000001

Control of Myeloid-specific Integrin αMβ2 (CD11b/CD18) Expression by Cytokines Is Regulated by Stat3-dependent Activation of PU.1

Authors: Panopoulos, Athanasia D., Bartos, David, Zhang, Ling, Watowich, Stephanie S. ^‡

Source: In Journal of Biological Chemistry 24 May 2002 277(21):19001-19007

iPSCs: Induced Back to Controversy

Authors: Panopoulos, Athanasia D., Ruiz, Sergio, Belmonte, Juan Carlos Izpisua

Source: In Cell Stem Cell 2011 8(4):347-348