Generating suspension-adapted human mesenchymal stromal cells (S-hMSCs) for the scalable manufacture of extracellular vesicles

Authors: Silva Couto, Pedro, Stibbs, Dale J., Sanchez, Braulio Carrillo, Khalife, Rana, Panagopoulou, Theano I., Barnes, Benjamin, George, Vaques, Taghizadeh, Rouzbeh R., Rafiq, Qasim A.

Source: In Cytotherapy December 2024 26(12):1532-1546

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions

Authors: Guitart, Amelie V., Panagopoulou, Theano I., Villacreces, Arnaud, Vukovic, Milica, Sepulveda, Catarina, Allen, Lewis, Carter, Roderick N., van de Lagemaat, Louie N., Morgan, Marcos, Giles, Peter

Source: Journal of experimental medicine. 214(3):719-736

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN610320440&indx=1&recIds=ETOCRN610320440

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance

Authors: Vukovic, Milica, Guitart, Amelie V., Sepulveda, Catarina, Villacreces, Arnaud, O Duibhir, Eoghan, Panagopoulou, Theano I., Ivens, Alasdair, Menendez-Gonzalez, Juan, Iglesias, Juan Manuel, Allen, Lewis

Source: Journal of experimental medicine. 212(13):2223-2234

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN604233328&indx=1&recIds=ETOCRN604233328

CAR-T immunotherapies: Biotechnological strategies to improve safety, efficacy and clinical outcome through CAR engineering

Authors: Panagopoulou, Theano I., Rafiq, Qasim A.

Source: Biotechnology advances. 37(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122012425.0x000001&indx=1&recIds=ETOCvdc_100122012425.0x000001

Adult hematopoietic stem cells lacking Hif-1α self-renew normally

Authors: Vukovic, Milica ^*, Sepulveda, Catarina ^*, Subramani, Chithra ^*, Guitart, Amélie V., Mohr, Jasmine, Allen, Lewis, Panagopoulou, Theano I., Paris, Jasmin, Lawson, Hannah, Villacreces, Arnaud, Armesilla-Diaz, Alejandro, Gezer, Deniz, Holyoake, Tessa L., Ratcliffe, Peter J., Kranc, Kamil R.

Source: In Blood 9 June 2016 127(23):2841-2846

CAR T cells targeting BAFF-R can overcome CD19 antigen loss in B cell malignancies.

Authors: Qin, Hong, Dong, Zhenyuan, Wang, Xiuli, Cheng, Wesley A., Wen, Feng, Xue, Weili, Sun, Han, Walter, Miriam, Wei, Guowei, Smith, D. Lynne, Sun, Xiuhua, Fei, Fan, Xie, Jianming, Panagopoulou, Theano I., Chen, Chun-Wei, Song, Joo Y., Aldoss, Ibrahim, Kayembe, Clarisse, Sarno, Luisa, Müschen, Markus

Source: Science Translational Medicine; 9/25/2019, Vol. 11 Issue 511, p1-11, 11p

Subject Terms: CD19 antigen, T cells, T cell receptors, B cells, RITUXIMAB, CHIMERIC antigen receptors, LYMPHOBLASTIC leukemia, ACUTE leukemia

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