First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

Authors: Smit, Merel J, Sander, Adam F, Ariaans, Maud B P A, Fougeroux, Cyrielle, Heinzel, Constanze, Fendel, Rolf, Esen, Meral, Kremsner, Peter G, ter Heine, Rob, Wertheim, Heiman F, Idorn, Manja, Riis Paludan, Søren, Underwood, Alexander P, Binderup, Alekxander, Ramirez, Santseharay, Bukh, Jens, Soegaard, Max, Erdogan, Sayit M, Gustavsson, Tobias, Clemmensen, Stine, Theander, Thor G, Salanti, Ali, Hamborg, Mette, de Jongh, Willem A, McCall, Matthew B B, Nielsen, Morten A, Mordmüller, Benjamin G, Dagil, Robert, Goksøyr, Louise, Hulen, Thomas M, Janitzek, Christoph, Jensen, Daniel S, Justesen, Sune, Khalifé, Paul K, Kreidenweiss, Andrea, Lança, Telma, Lie-Andersen, Olivia, Teelen, Karina, Vidal-Calvo, Elena, Paludan, Søren Riis

Source: In The Lancet Microbe March 2023 4(3):e140-e148

The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice.

Authors: Ben Abdallah, Hakim, Marino, Giorgia, Idorn, Manja, S. Reinert, Line, Bregnhøj, Anne, Paludan, Søren Riis, Johansen, Claus

Source: PLoS ONE; 9/26/2024, Vol. 19 Issue 9, p1-13, 13p

Subject Terms: SARS-CoV-2, CORONAVIRUS disease treatment, COVID-19, VIRUS diseases, COVID-19 treatment

Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death

Authors: Reimer, Lasse, Vesterager, Louise Buur, Betzer, Cristine, Zheng, Jin, Nielsen, Lærke Dalsgaard, Kofoed, Rikke Hahn, Lassen, Louise Berkhoudt, Bølcho, Ulrik, Paludan, Søren Riis, Fog, Karina, Jensen, Poul Henning

Source: In Neurobiology of Disease July 2018 115:17-28

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication

Authors: Mauthe, Mario, Langereis, Martijn, Jung, Jennifer, Zhou, Xingdong, Jones, Alex, Omta, Wienand, Tooze, Sharon A., Stork, Björn, Paludan, Søren Riis, Ahola, Tero

Source: Journal of cell biology. 214(5):619-635

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN607712220&indx=1&recIds=ETOCRN607712220

Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages.

Authors: Andersen, Line Lykke, Huang, Yiqi, Urban, Christian, Oubraham, Lila, Winheim, Elena, Stafford, Che, Nagl, Dennis, O'Duill, Fionan, Ebert, Thomas, Engleitner, Thomas, Paludan, Søren Riis, Krug, Anne, Rad, Roland, Hornung, Veit, Pichlmair, Andreas

Source: EMBO Journal; Dec2023, Vol. 42 Issue 23, p1-19, 19p

Subject Terms: IMMUNOMODULATORS, CYTOKINE receptors, CELL receptors, VIRAL replication, AP-1 transcription factor, SEMLIKI Forest virus, ADENINE

Corona's new coat: SARS-CoV-2 in Danish minks and implications for travel medicine

Authors: Larsen, Carsten Schade, Paludan, Søren Riis

Source: Travel medicine and infectious disease. 38

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117061557.0x000001&indx=1&recIds=ETOCvdc_100117061557.0x000001

Pattern recognition receptor responses in children with chronic hepatitis B virus infection

Authors: Heiberg, Ida Louise, Winther, Thilde Nordmann, Paludan, Søren Riis, Hogh, Birthe

Source: In Journal of Clinical Virology July 2012 54(3):229-234

HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0

Authors: Hensel, Niko, Raker, Verena, Förthmann, Benjamin, Detering, Nora Tula, Kubinski, Sabrina, Buch, Anna, Katzilieris-Petras, Georgios, Spanier, Julia, Gudi, Viktoria, Wagenknecht, Sylvia, Kopfnagel, Verena, Werfel, Thomas Andreas, Stangel, Martin, Beineke, Andreas, Kalinke, Ulrich, Paludan, Søren Riis, Sodeik, Beate, Claus, Peter

Source: Journal of neuroinflammation. 16(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192949909.0x000001&indx=1&recIds=ETOCvdc_100192949909.0x000001

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