Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3

Authors: Oldoni, Federico, Palmen, Jutta, Giambartolomei, Claudia, Howard, Philip, Drenos, Fotios, Plagnol, Vincent, Humphries, Steve E., Talmud, Philippa J., Smith, Andrew J.P.

Source: In Atherosclerosis March 2016 246:193-201

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

Authors: Swerdlow, Daniel I, Preiss, David, Kuchenbaecker, Karoline B, Holmes, Michael V, Engmann, Jorgen E L, Shah, Tina, Sofat, Reecha, Stender, Stefan, Johnson, Paul C D, Scott, Robert A, Leusink, Maarten, Verweij, Niek, Sharp, Stephen J, Guo, Yiran, Giambartolomei, Claudia, Chung, Christina, Peasey, Anne, Amuzu, Antoinette, Li, KaWah, Palmen, Jutta, Howard, Philip, Cooper, Jackie A, Drenos, Fotios, Li, Yun R, Lowe, Gordon, Gallacher, John, Stewart, Marlene C W, Tzoulaki, Ioanna, Buxbaum, Sarah G, van der A, Daphne L, Forouhi, Nita G, Onland-Moret, N Charlotte, van der Schouw, Yvonne T, Schnabel, Renate B, Hubacek, Jaroslav A, Kubinova, Ruzena, Baceviciene, Migle, Tamosiunas, Abdonas, Pajak, Andrzej, Topor-Madry, Romanvan, Stepaniak, Urszula, Malyutina, Sofia, Baldassarre, Damiano, Sennblad, Bengt, Tremoli, Elena, de Faire, Ulf, Veglia, Fabrizio, Ford, Ian, Jukema, J Wouter, Westendorp, Rudi G J, de Borst, Gert Jan, de Jong, Pim A, Algra, Ale, Spiering, Wilko, der Zee, Anke H Maitland-van, Klungel, Olaf H, de Boer, Anthonius, Doevendans, Pieter A, Eaton, Charles B, Robinson, Jennifer G, Duggan, David, Kjekshus, John, Downs, John R, Gotto, Antonio M, Keech, Anthony C, Marchioli, Roberto, Tognoni, Gianni, Sever, Peter S, Poulter, Neil R, Waters, David D, Pedersen, Terje R, Amarenco, Pierre, Nakamura, Haruo, McMurray, John J V, Lewsey, James D, Chasman, Daniel I, Ridker, Paul M, Maggioni, Aldo P, Tavazzi, Luigi, Ray, Kausik K, Seshasai, Sreenivasa Rao Kondapally, Manson, JoAnn E, Price, Jackie F, Whincup, Peter H, Morris, Richard W, Lawlor, Debbie A, Smith, George Davey, Ben-Shlomo, Yoav, Schreiner, Pamela J, Fornage, Myriam, Siscovick, David S, Cushman, Mary, Kumari, Meena, Wareham, Nick J, Verschuren, W M Monique, Redline, Susan, Patel, Sanjay R, Whittaker, John C, Hamsten, Anders, Delaney, Joseph A, Dale, Caroline, Gaunt, Tom R, Wong, Andrew, Kuh, Diana, Hardy, Rebecca, Kathiresan, Sekar, Castillo, Berta A, van der Harst, Pim, Brunner, Eric J, Tybjaerg-Hansen, Anne, Marmot, Michael G, Krauss, Ronald M, Tsai, Michael, Coresh, Josef, Hoogeveen, Ronald C, Psaty, Bruce M, Lange, Leslie A, Hakonarson, Hakon, Dudbridge, Frank, Humphries, Steve E, Talmud, Philippa J, Kivimäki, Mika, Timpson, Nicholas J, Langenberg, Claudia, Asselbergs, Folkert W, Voevoda, Mikhail, Bobak, Martin, Pikhart, Hynek, Wilson, James G, Reiner, Alex P, Keating, Brendan J, Hingorani, Aroon D, Sattar, Naveed

Source: In The Lancet 24-30 January 2015 385(9965):351-361

A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease

Authors: Holmes, Michael V., Frikke-Schmidt, Ruth, Melis, Daniela, Luben, Robert, Asselbergs, Folkert W., Boer, Jolanda M.A., Cooper, Jackie, Palmen, Jutta, Horvat, Pia, Engmann, Jorgen, Li, Ka-Wah, Onland-Moret, N. Charlotte, Hofker, Marten H., Kumari, Meena, Keating, Brendan J., Hubacek, Jaroslav A., Adamkova, Vera, Kubinova, Ruzena, Bobak, Martin, Khaw, Kay-Tee, Nordestgaard, Børge G., Wareham, Nick, Humphries, Steve E., Langenberg, Claudia, Tybjaerg-Hansen, Anne, Talmud, Philippa J.

Source: In Atherosclerosis November 2014 237(1):5-12

Association between alcohol and cardiovascular disease : Mendelian randomisation analysis based on individual participant data

Authors: IMPROVE study group, The InterAct Consortium, Holmes, Michael V, Dale, Caroline E, Zuccolo, Luisa, Silverwood, Richard J, Guo, Yiran, Ye, Zheng, Prieto-Merino, David, Dehghan, Abbas, Trompet, Stella, Wong, Andrew, Cavadino, Alana, Drogan, Dagmar, Padmanabhan, Sandosh, Li, Shanshan, Yesupriya, Ajay, Leusink, Maarten, Sundstrom, Johan, Hubacek, Jaroslav A, Pikhart, Hynek, Swerdlow, Daniel I, Panayiotou, Andrie G, Borinskaya, Svetlana A, Finan, Chris, Shah, Sonia, Kuchenbaecker, Karoline B, Shah, Tina, Engmann, Jorgen, Folkersen, Lasse, Eriksson, Per, Ricceri, Fulvio, Melander, Olle, Sacerdote, Carlotta, Gamble, Dale M, Rayaprolu, Sruti, Ross, Owen A, McLachlan, Stela, Vikhireva, Olga, Sluijs, Ivonne, Scott, Robert A, Adamkova, Vera, Flicker, Leon, van Bockxmeer, Frank M, Power, Christine, Marques-Vidal, Pedro, Meade, Tom, Marmot, Michael G, Ferro, Jose M, Paulos-Pinheiro, Sofia, Humphries, Steve E, Talmud, Philippa J, Leach, Irene Mateo, Verweij, Niek, Linneberg, Allan, Skaaby, Tea, Doevendans, Pieter A, Cramer, Maarten J, van der Harst, Pim, Klungel, Olaf H, Dowling, Nicole F, Dominiczak, Anna F, Kumari, Meena, Nicolaides, Andrew N, Weikert, Cornelia, Boeing, Heiner, Ebrahim, Shah, Gaunt, Tom R, Price, Jackie F, Lannfelt, Lars, Peasey, Anne, Kubinova, Ruzena, Pajak, Andrzej, Malyutina, Sofia, Voevoda, Mikhail I, Tamosiunas, Abdonas, Maitland-vanderZee, Anke H, Norman, Paul E, Hankey, Graeme J, Bergmann, Manuela M, Hofman, Albert, Franco, Oscar H, Cooper, Jackie, Palmen, Jutta, Spiering, Wilko, de Jong, Pim A, Kuh, Diana, Hardy, Rebecca, Uitterlinden, Andre G, Ikram, M Arfan, Ford, Ian, Hyppönen, Elina, Almeida, Osvaldo P, Wareham, Nicholas J, Khaw, Kay-Tee, Hamsten, Anders, Husemoen, Lise Lotte N, Tjønneland, Anne, Tolstrup, Janne S, Rimm, Eric, Beulens, Joline W J, Verschuren, W M Monique, Onland-Moret, N Charlotte, Hofker, Marten H, Wannamethee, S Goya, Whincup, Peter H, Morris, Richard, Vicente, Astrid M, Watkins, Hugh, Farrall, Martin, Jukema, J Wouter, Meschia, James, Cupples, L Adrienne, Sharp, Stephen J, Fornage, Myriam, Kooperberg, Charles, LaCroix, Andrea Z, Dai, James Y, Lanktree, Matthew B, Siscovick, David S, Jorgenson, Eric, Spring, Bonnie, Coresh, Josef, Li, Yun R, Buxbaum, Sarah G, Schreiner, Pamela J, Curtis, R, Y Tsai, Michael, Patel, Sanjay R, Redline, Susan, Johnson, Andrew D, Hoogeveen, Ron C, Hakonarson, Hakon, Rotter, Jerome I, Boerwinkle, Eric, de Bakker, Paul I W, Kivimaki, Mika, Asselbergs, Folkert W, Sattar, Naveed, Lawlor, Debbie A, Whittaker, John, Smith, George Davey, Mukamal, Kenneth, Psaty, Bruce M, Wilson, James G, Lange, Leslie A, Hamidovic, Ajna, Hingorani, Aroon D, Nordestgaard, Børge G, Bobak, Martin, Leon, David A, Langenberg, Claudia, Palmer, Tom M, Reiner, Alex P, Keating, Brendan J, Dudbridge, Frank, Casas, Juan P

Source: BMJ: British Medical Journal, 2014 Jul 01. 349

Access URL: https://www.jstor.org/stable/26516453

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

Authors: Saxena, Richa, Elbers, Clara C., Guo, Yiran, Peter, Inga, Gaunt, Tom R., Mega, Jessica L., Lanktree, Matthew B., Tare, Archana, Castillo, Berta Almoguera, Li, Yun R., Johnson, Toby, Bruinenberg, Marcel, Gilbert-Diamond, Diane, Rajagopalan, Ramakrishnan, Voight, Benjamin F., Balasubramanyam, Ashok, Barnard, John, Bauer, Florianne, Baumert, Jens, Bhangale, Tushar, Böhm, Bernhard O., Braund, Peter S., Burton, Paul R., Chandrupatla, Hareesh R., Clarke, Robert, Cooper-DeHoff, Rhonda M., Crook, Errol D., Davey-Smith, George, Day, Ian N., de Boer, Anthonius, de Groot, Mark C.H., Drenos, Fotios, Ferguson, Jane, Fox, Caroline S., Furlong, Clement E., Gibson, Quince, Gieger, Christian, Gilhuijs-Pederson, Lisa A., Glessner, Joseph T., Goel, Anuj, Gong, Yan, Grant, Struan F.A., Grobbee, Diederick E., Hastie, Claire, Humphries, Steve E., Kim, Cecilia E., Kivimaki, Mika, Kleber, Marcus, Meisinger, Christa, Kumari, Meena, Langaee, Taimour Y., Lawlor, Debbie A., Li, Mingyao, Lobmeyer, Maximilian T., Maitland-van der Zee, Anke-Hilse, Meijs, Matthijs F.L., Molony, Cliona M., Morrow, David A., Murugesan, Gurunathan, Musani, Solomon K., Nelson, Christopher P., Newhouse, Stephen J., O'Connell, Jeffery R., Padmanabhan, Sandosh, Palmen, Jutta, Patel, Sanjey R., Pepine, Carl J., Pettinger, Mary, Price, Thomas S., Rafelt, Suzanne, Ranchalis, Jane, Rasheed, Asif, Rosenthal, Elisabeth, Ruczinski, Ingo, Shah, Sonia, Shen, Haiqing, Silbernagel, Günther, Smith, Erin N., Spijkerman, Annemieke W.M., Stanton, Alice, Steffes, Michael W., Thorand, Barbara, Trip, Mieke, van der Harst, Pim, van der A, Daphne L., van Iperen, Erik P.A., van Setten, Jessica, van Vliet-Ostaptchouk, Jana V., Verweij, Niek, Wolffenbuttel, Bruce H.R., Young, Taylor, Zafarmand, M. Hadi, Zmuda, Joseph M., Boehnke, Michael, Altshuler, David, McCarthy, Mark, Kao, W.H. Linda, Pankow, James S., Cappola, Thomas P., Sever, Peter, Poulter, Neil, Caulfield, Mark, Dominiczak, Anna, Shields, Denis C., Bhatt, Deepak L., Zhang, Li, Curtis, Sean P., Danesh, John, Casas, Juan P., van der Schouw, Yvonne T., Onland-Moret, N. Charlotte, Doevendans, Pieter A., Dorn, Gerald W., II, Farrall, Martin, FitzGerald, Garret A., Hamsten, Anders, Hegele, Robert, Hingorani, Aroon D., Hofker, Marten H., Huggins, Gordon S., Illig, Thomas, Jarvik, Gail P., Johnson, Julie A., Klungel, Olaf H., Knowler, William C., Koenig, Wolfgang, März, Winfried, Meigs, James B., Melander, Olle, Munroe, Patricia B., Mitchell, Braxton D., Bielinski, Susan J., Rader, Daniel J., Reilly, Muredach P., Rich, Stephen S., Rotter, Jerome I., Saleheen, Danish, Samani, Nilesh J., Schadt, Eric E., Shuldiner, Alan R., Silverstein, Roy, Kottke-Marchant, Kandice, Talmud, Philippa J., Watkins, Hugh, Asselbergs, Folkert W., de Bakker, Paul I.W., McCaffery, Jeanne, Wijmenga, Cisca, Sabatine, Marc S., Wilson, James G., Reiner, Alex, Bowden, Donald W., Hakonarson, Hakon, Siscovick, David S., Keating, Brendan J.

Source: In The American Journal of Human Genetics 9 March 2012 90(3):410-425

Blood Pressure Loci Identified with a Gene-Centric Array

Authors: Johnson, Toby, Gaunt, Tom R., Newhouse, Stephen J., Padmanabhan, Sandosh, Tomaszewski, Maciej, Kumari, Meena, Morris, Richard W., Tzoulaki, Ioanna, O'Brien, Eoin T., Poulter, Neil R., Sever, Peter, Shields, Denis C., Thom, Simon, Wannamethee, Sasiwarang G., Whincup, Peter H., Brown, Morris J., Connell, John M., Dobson, Richard J., Howard, Philip J., Mein, Charles A., Onipinla, Abiodun, Shaw-Hawkins, Sue, Zhang, Yun, Smith, George Davey, Day, Ian N.M., Lawlor, Debbie A., Goodall, Alison H., Fowkes, F. Gerald, Abecasis, Gonçalo R., Elliott, Paul, Gateva, Vesela, Braund, Peter S., Burton, Paul R., Nelson, Christopher P., Tobin, Martin D., van der Harst, Pim, Glorioso, Nicola, Neuvrith, Hani, Salvi, Erika, Staessen, Jan A., Stucchi, Andrea, Devos, Nabila, Jeunemaitre, Xavier, Plouin, Pierre-François, Tichet, Jean, Juhanson, Peeter, Org, Elin, Putku, Margus, Sõber, Siim, Veldre, Gudrun, Viigimaa, Margus, Levinsson, Anna, Rosengren, Annika, Thelle, Dag S., Hastie, Claire E., Hedner, Thomas, Lee, Wai K., Melander, Olle, Wahlstrand, Björn, Hardy, Rebecca, Wong, Andrew, Cooper, Jackie A., Palmen, Jutta, Chen, Li, Stewart, Alexandre F.R., Wells, George A., Westra, Harm-Jan, Wolfs, Marcel G.M., Clarke, Robert, Franzosi, Maria Grazia, Goel, Anuj, Hamsten, Anders, Lathrop, Mark, Peden, John F., Seedorf, Udo, Watkins, Hugh, Ouwehand, Willem H., Sambrook, Jennifer, Stephens, Jonathan, Casas, Juan-Pablo, Drenos, Fotios, Holmes, Michael V., Kivimaki, Mika, Shah, Sonia, Shah, Tina, Talmud, Philippa J., Whittaker, John, Wallace, Chris, Delles, Christian, Laan, Maris, Kuh, Diana, Humphries, Steve E., Nyberg, Fredrik, Cusi, Daniele, Roberts, Robert, Newton-Cheh, Christopher, Franke, Lude, Stanton, Alice V., Dominiczak, Anna F., Farrall, Martin, Hingorani, Aroon D., Samani, Nilesh J., Caulfield, Mark J., Munroe, Patricia B.

Source: In The American Journal of Human Genetics 9 December 2011 89(6):688-700

Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1

Authors: Bown, Matthew J., Jones, Gregory T., Harrison, Seamus C., Wright, Benjamin J., Bumpstead, Suzannah, Baas, Annette F., Gretarsdottir, Solveig, Badger, Stephen A., Bradley, Declan T., Burnand, Kevin, Child, Anne H., Clough, Rachel E., Cockerill, Gillian, Hafez, Hany, Scott, D. Julian A., Futers, Simon, Johnson, Anne, Sohrabi, Soroush, Smith, Alberto, Thompson, Matthew M., van Bockxmeer, Frank M., Waltham, Matthew, Matthiasson, Stefan E., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Blankensteijn, Jan D., Teijink, Joep A.W., Wijmenga, Cisca, de Graaf, Jacqueline, Kiemeney, Lambertus A., Assimes, Themistocles L., McPherson, Ruth, Folkersen, Lasse, Franco-Cereceda, Anders, Palmen, Jutta, Smith, Andrew J., Sylvius, Nicolas, Wild, John B., Refstrup, Mette, Edkins, Sarah, Gwilliam, Rhian, Hunt, Sarah E., Potter, Simon, Lindholt, Jes S., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Hughes, Anne E., Golledge, Jonathan, Norman, Paul E., van Rij, Andre, Powell, Janet T., Eriksson, Per, Stefansson, Kari, Thompson, John R., Humphries, Steve E., Sayers, Robert D., Deloukas, Panos, Samani, Nilesh J.

Source: In The American Journal of Human Genetics 11 November 2011 89(5):619-627

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Authors: Lanktree, Matthew B., Guo, Yiran, Murtaza, Muhammed, Glessner, Joseph T., Bailey, Swneke D., Onland-Moret, N. Charlotte, Lettre, Guillaume, Ongen, Halit, Rajagopalan, Ramakrishnan, Johnson, Toby, Shen, Haiqing, Nelson, Christopher P., Klopp, Norman, Baumert, Jens, Padmanabhan, Sandosh, Pankratz, Nathan, Pankow, James S., Shah, Sonia, Taylor, Kira, Barnard, John, Peters, Bas J., M. Maloney, Cliona, Lobmeyer, Maximilian T., Stanton, Alice, Zafarmand, M. Hadi, Romaine, Simon P.R., Mehta, Amar, van Iperen, Erik P.A., Gong, Yan, Price, Tom S., Smith, Erin N., Kim, Cecilia E., Li, Yun R., Asselbergs, Folkert W., Atwood, Larry D., Bailey, Kristian M., Bhatt, Deepak, Bauer, Florianne, Behr, Elijah R., Bhangale, Tushar, Boer, Jolanda M.A., Boehm, Bernhard O., Bradfield, Jonathan P., Brown, Morris, Braund, Peter S., Burton, Paul R., Carty, Cara, Chandrupatla, Hareesh R., Chen, Wei, Connell, John, Dalgeorgou, Chrysoula, Boer, Anthonius de, Drenos, Fotios, Elbers, Clara C., Fang, James C., Fox, Caroline S., Frackelton, Edward C., Fuchs, Barry, Furlong, Clement E., Gibson, Quince, Gieger, Christian, Goel, Anuj, Grobbee, Diederik E., Hastie, Claire, Howard, Philip J., Huang, Guan-Hua, Johnson, W. Craig, Li, Qing, Kleber, Marcus E., Klein, Barbara E.K., Klein, Ronald, Kooperberg, Charles, Ky, Bonnie, LaCroix, Andrea, Lanken, Paul, Lathrop, Mark, Li, Mingyao, Marshall, Vanessa, Melander, Olle, Mentch, Frank D., J. Meyer, Nuala, Monda, Keri L., Montpetit, Alexandre, Murugesan, Gurunathan, Nakayama, Karen, Nondahl, Dave, Onipinla, Abiodun, Rafelt, Suzanne, Newhouse, Stephen J., Otieno, F. George, Patel, Sanjey R., Putt, Mary E., Rodriguez, Santiago, Safa, Radwan N., Sawyer, Douglas B., Schreiner, Pamela J., Simpson, Claire, Sivapalaratnam, Suthesh, Srinivasan, Sathanur R., Suver, Christine, Swergold, Gary, Sweitzer, Nancy K., Thomas, Kelly A., Thorand, Barbara, Timpson, Nicholas J., Tischfield, Sam, Tobin, Martin, Tomaszweski, Maciej, Verschuren, W.M. Monique, Wallace, Chris, Winkelmann, Bernhard, Zhang, Haitao, Zheng, Dongling, Zhang, Li, Zmuda, Joseph M., Clarke, Robert, Balmforth, Anthony J., Danesh, John, Day, Ian N., Schork, Nicholas J., de Bakker, Paul I.W., Delles, Christian, Duggan, David, Hingorani, Aroon D., Hirschhorn, Joel N., Hofker, Marten H., Humphries, Steve E., Kivimaki, Mika, Lawlor, Debbie A., Kottke-Marchant, Kandice, Mega, Jessica L., Mitchell, Braxton D., Morrow, David A., Palmen, Jutta, Redline, Susan, Shields, Denis C., Shuldiner, Alan R., Sleiman, Patrick M., Smith, George Davey, Farrall, Martin, Jamshidi, Yalda, Christiani, David C., Casas, Juan P., Hall, Alistair S., Doevendans, Pieter A., D. Christie, Jason, Berenson, Gerald S., Murray, Sarah S., Illig, Thomas, Dorn, Gerald W., II, Cappola, Thomas P., Boerwinkle, Eric, Sever, Peter, Rader, Daniel J., Reilly, Muredach P., Caulfield, Mark, Talmud, Philippa J., Topol, Eric, Engert, James C., Wang, Kai, Dominiczak, Anna, Hamsten, Anders, Curtis, Sean P., Silverstein, Roy L., Lange, Leslie A., Sabatine, Marc S., Trip, Mieke, Saleheen, Danish, Peden, John F., Cruickshanks, Karen J., März, Winfried, O'Connell, Jeffrey R., Klungel, Olaf H., Wijmenga, Cisca, Maitland-van der Zee, Anke Hilse, Schadt, Eric E., Johnson, Julie A., Jarvik, Gail P., Papanicolaou, George J., Grant, Struan F.A., Munroe, Patricia B., North, Kari E., Samani, Nilesh J., Koenig, Wolfgang, Gaunt, Tom R., Anand, Sonia S., van der Schouw, Yvonne T., Soranzo, Nicole, FitzGerald, Garret A., Reiner, Alex, Hegele, Robert A., Hakonarson, Hakon, Keating, Brendan J.

Source: In The American Journal of Human Genetics 7 January 2011 88(1):6-18

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

Authors: Zabaneh, Delilah, Kumari, Meena, Sandhu, Manj, Wareham, Nick, Wainwright, Nick, Papamarkou, Theodore, Hopewell, Jemma, Clarke, Robert, Li, KaWah, Palmen, Jutta, Talmud, Philippa J., Kronenberg, Florian, Lamina, Claudia, Summerer, Monika, Paulweber, Bernhard, Price, Jackie, Fowkes, Gerry, Stewart, Marlene, Drenos, Fotios, Shah, Sonia, Shah, Tina, Casas, Juan-Pablo, Kivimaki, Mika, Whittaker, John, Hingorani, Aroon D., Humphries, Steve E.

Source: In Atherosclerosis 2011 217(2):447-451

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Authors: Talmud, Philippa J., Drenos, Fotios, Shah, Sonia, Shah, Tina, Palmen, Jutta, Verzilli, Claudio, Gaunt, Tom R., Pallas, Jacky, Lovering, Ruth, Li, Kawah, Casas, Juan Pablo, Sofat, Reecha, Kumari, Meena, Rodriguez, Santiago, Johnson, Toby, Newhouse, Stephen J., Dominiczak, Anna, Samani, Nilesh J., Caulfield, Mark, Sever, Peter, Stanton, Alice, Shields, Denis C., Padmanabhan, Sandosh, Melander, Olle, Hastie, Claire, Delles, Christian, Ebrahim, Shah, Marmot, Michael G., Smith, George Davey, Lawlor, Debbie A., Munroe, Patricia B., Day, Ian N., Kivimaki, Mika, Whittaker, John, Humphries, Steve E., Hingorani, Aroon D.

Source: In The American Journal of Human Genetics 13 November 2009 85(5):628-642

The functional interaction on in vitro gene expression of APOA5 SNPs, defining haplotype APOA5⁎2, and their paradoxical association with plasma triglyceride but not plasma apoAV levels

Authors: Palmen, Jutta, Smith, Andrew J.P., Dorfmeister, Birgit, Putt, Wendy, Humphries, Steve E., Talmud, Philippa J.

Source: In BBA - Molecular Basis of Disease 2008 1782(7):447-452

Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study

Authors: Vaessen, Stefan F.C. ^*, Schaap, Frank G., Kuivenhoven, Jan-Albert ^*, Groen, Albert K., Hutten, Barbara A., Boekholdt, S. Matthijs ^**, Hattori, Hiroaki, Sandhu, Manjinder S., Bingham, Sheila A. ^***, Luben, Robert, Palmen, Jutta A., Wareham, Nicholas J., Humphries, Steve E., Kastelein, John J.P. ^*, Talmud, Philippa J., Khaw, Kay-Tee

Source: In Journal of Lipid Research September 2006 47(9):2064-2070

Determination of the Functionality of Common APOA5 Polymorphisms

Authors: Talmud, Philippa J. ^{‡, §}, Palmen, Jutta ^‡, Putt, Wendy ^‡, Lins, Laurence ^¶, Humphries, Steve E. ^‡

Source: In Journal of Biological Chemistry 5 August 2005 280(31):28215-28220

Investigation into the role of the hormone sensitive lipase −60C > G promoter variant in morbid obesity

Authors: Talmud, Philippa J., Palmen, Jutta, Wolf, Anna M., Beisiegel, Ulrike

Source: In Nutrition, Metabolism and Cardiovascular Diseases 2005 15(1):31-35

Functional analysis of four LDLR 5′UTR and promoter variants in patients with familial hypercholesterolaemia.

Authors: Khamis, Amna¹, Palmen, Jutta¹, Lench, Nick², Taylor, Alison², Badmus, Ebele¹, Leigh, Sarah¹, Humphries, Steve E¹

Source: European Journal of Human Genetics. Jun2015, Vol. 23 Issue 6, p790-795. 6p.

Subject Terms: *FAMILIAL diseases, *LIPOPROTEIN lipase, *FAMILIAL hypophosphatemia, *LUCIFERASE genetics, *FUNCTIONAL analysis

Variation in the promoter of the human hormone sensitive lipase gene shows gender specific effects on insulin and lipid levels: results from the Ely study

Authors: Talmud, Philippa J ^*, Palmen, Jutta, Luan, Jian’an, Flavell, Dave, Byrne, Christopher D, Waterworth, Dawn M, Wareham, Nicholas J

Source: In BBA - Molecular Basis of Disease 2001 1537(3):239-244

Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform.

Authors: George, Marc J., Kleveland, Ola, Garcia-Hernandez, Jorge, Palmen, Jutta, Lovering, Ruth, Wiseth, Rune, Aukrust, Pål, Engmann, Jorgen, Damås, Jan Kristian, Hingorani, Aroon D., Gullestad, Lars, Casas, Juan P., Ueland, Thor

Source: Journal of the American Heart Association; 6/16/2020, Vol. 9 Issue 12, p1-21, 21p

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Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays.

Authors: Smith, Andrew J. P.¹, Andrew.J.P.Smith@ucl.ac.uk, Howard, Philip¹, Shah, Sonia², Eriksson, Per³, Stender, Stefan, Giambartolomei, Claudia², Folkersen, Lasse³, Tybjærg-Hansen, Anne^4,5, Kumari, Meena⁶, Hingorani, Aroon D.⁷, Talmud, Philippa J.¹, Humphries, Steve E.¹, Palmen, Jutta¹

Source: PLoS Genetics; Aug2012, Vol. 8 Issue 8, Special section p1-10, 10p, 1 Diagram, 4 Charts, 7 Graphs